Abstract: Replicated polymeric microstructures have been used in the fabrication of optofiber waveguide connections, with the intention of simplifying the production of such connections, and therewith greatly reduce manufacturing costs. Fabrication is commenced from a silicon chip in which there has been etched grooves whose cross-sectional shape has been adapted to accommodate waveguides, such as optofibers. Firstly, the silicon chip is replicated, by plating the silicon chip with nickel for instance. The replication then serves as a model for producing a plastic copy of the silicon chip. This method of manufacture is able to produce waveguide accommodating grooves (2), such as optofiber accommodating grooves, to a very high degree of accuracy. Furthermore, the method provides a high degree of freedom in the configuration of the grooves, and also enables branched grooves for receiving branched fibres to be produced.

Abstract: A method for the manufacture of a microstructure having a top face and a bottom face, at least one hole or cavity therein extending from the top face to the bottom face, and a polymer membrane which extends over a bottom opening of said hole or cavity, which method comprises the steps of: providing a substrate body having said top and bottom faces, optionally forming at least part of said at least one hole or cavity in the substrate body, providing a membrane support at the bottom face opening of said at least one hole or cavity, depositing a layer of polymer material onto the bottom face of said substrate body against said membrane support, if required, completing the formation of the at least one hole or cavity, and, if not done in this step, selectively removing said membrane support to bare said polymer membrane over the bottom opening of the at least one hole or cavity.

Abstract: A leakage-proof sealing means is provided in a microfluidic channel assembly of the type having first and second flat surface members which when pressed against each other define a microfluidic channel system between them, by recessing a sealing groove structure into the flat surface of the first member, and applying against the first member a counter mould surface having an aligned groove and/or ridge structure of smaller width than the sealing groove structure to define a mould cavity therewith, into which a fluid sealing material is introduced and hardened to form a resilient seal, the top part of which projects above the edges of the sealing groove structure while leaving sufficient space in the upper part thereof to permit complete accommodation of the top part of the resilient seal when compressed by the second assembly member.

Abstract: The microfluidic structure comprises first and second substantially planar form-stable base layers and an intermediate spacing layer of elastic material, said spacing layer being recessed to define a microcavity or channel system with at least one of said first and second base layers. The structure is produced by moulding the spacing layer, optionally applied to or integral with a first base layer, against a planar mould, and the microcavity or channel system is completed by applying a second base layer, and optionally said first base layer, to the spacing layer.