Patents by Inventor Paramjit S. Arora

Paramjit S. Arora has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITING INTERACTION BETWEEN THE HIF-1ALPHA AND p300/CBP WITH HYDROGEN BOND SURROGATE-BASED
    Publication number: 20110245175
    Abstract: The present invention relates to peptides having one or more stable, internally constrained ?-helices, and that include a sequence that mimics at least a portion of the C-terminal transactivation domain of HIF-1?. Also disclosed are pharmaceutical compositions containing these peptides and methods of using these peptides, for example to reduce gene transcription, treat or prevent disorders mediated by interaction of HIF-1? with CREB-binding protein and/or p300, reduce or prevent angiogenesis in a tissue, induce apoptosis, decrease cell survival and/or proliferation, and identify potential ligands of CREB-binding protein and/or p300.
    Type: Application
    Filed: September 18, 2009
    Publication date: October 6, 2011
    Applicants: New York University, The Arizona Board of Regents on behalf of the University of Arizona
    Inventors: Paramjit S. Arora, Bogdan Olenyuk, Ross N. Chapman, Laura Henchey, Katherine M. Block
  • Methods for preparing nonpeptidic oligomers from amino acids
    Patent number: 7834038
    Abstract: The present invention relates to nonpeptidic oligomers. Methods for preparing nonpeptidic oligomers from amino acids by replacing the amide bond with heterocyclic rings are also disclosed.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: November 16, 2010
    Assignee: New York University
    Inventors: Paramjit S. Arora, Nicholas G. Angelo
  • SYSTEM AND USES FOR GENERATING DATABASES OF PROTEIN SECONDARY STRUCTURES INVOLVED IN INTER-CHAIN PROTEIN INTERACTIONS
    Publication number: 20100281003
    Abstract: The present invention relates to methods and systems for generating a database of protein secondary structures that are at an interface of a two-chain inter-protein interaction. Collections of secondary structures identified according to the methods disclosed herein, and their use in identifying therapeutic drug candidates potentially effective in modulating a two-chain inter-protein interaction having a secondary structure at its interface, are also disclosed.
    Type: Application
    Filed: April 2, 2010
    Publication date: November 4, 2010
    Applicant: NEW YORK UNIVERSITY
    Inventors: Andrea L. JOCHIM, Paramjit S. ARORA