Abstract: A diving computer is provided. The diving computer includes a computer connected to a dot matrix screen to display information concerning a dive. The computer has an interface to an external personal computer for reprogrammably configuring the information displayed on the screen. The user may customize the information on one or more views of the screen in several ways. The user may select the desired information to be displayed, and may customize the size and placement of the information on one or more views. The diving computer also has a number of pre-programmed displays that may be selected, each of which present different layouts and organizations of diving related information.

Abstract: The present invention relates to compounds that are capable of modulating CD154 mobilization and that are useful for stabilizing the thrombotic process and reducing the activation of cells involved in an inflammatory response. The present invention also relates to methods useful for identifying such compounds. The present invention also relates to the treatment of platelets for transfusion with metalloproteinase inhibitors to treat or prevent inflammation. The present invention also includes compositions and methods to treat injury and disease related to such biological processes.

Abstract: The invention relates to a support tube for a shrink sleeve for an electric cable joint, the tube serving to support a sleeve in an expanded state and then to be removed so as to allow the sleeve to shrink onto the joint. According to the invention, the support tube is constituted by an open tube fitted on its two longitudinal edges with mutual engagement means.

Abstract: An instrument for capturing an image of thrombus formation, blood coagulation, recruitment of circulating inflammatory or tumour cells in a blood sample. The instrument comprises a member defining a channel therethrough, a fluid handling assembly that permits the blood sample to move through the channel at a flow rate, and an imaging assembly including a microscopy device. The imaging assembly is disposed relative to the channel so as to capture light rays defining the image of thrombus formation in the channel.

Abstract: The present invention relates to methods and compositions for identifying and treating subjects in need of antithrombotic therapies but who are not responsive to aspirin.

Abstract: The present invention provides novel compositions and methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient undergoing a vascular intervention. More particularly, the present invention provides intravascular devices coated with one or more spleen tyrosine kinase (Syk) inhibitors. Methods for inhibiting restenosis, thrombosis, and/or inflammation in a patient by treatment with such intravascular devices are also provided. In addition, the present invention provides methods for treating sickle cell disease using Syk inhibitors.

Abstract: The present invention identifies P-selectin as a modulator of hemostasis. Accordingly, the present invention relates to methods for the identification and use of modulators of P-selectin activity as modulators of hemostasis. The invention also relates to methods and compositions for the diagnosis and treatment of hemostatic disorders, including, but not limited to, hemorrhagic disorders and thrombotic disorders. The present invention describes methods for the diagnostic evaluation and prognosis of various hemostatic conditions, and for the identification of subjects exhibiting a predisposition to such conditions. In addition, the present invention provides methods for the diagnostic monitoring of patients undergoing clinical evaluation for the treatment of a hemostatic or vascular disorders, and for monitoring the efficacy of compounds in clinical trials.

Abstract: The present invention relates to compounds that are capable of modulating CD154 mobilization and that are useful for stabilizing the thrombotic process and reducing the activation of cells involved in an inflammatory response. The present invention also relates to methods useful for identifying such compounds. The present invention also relates to the treatment of platelets for transfusion with metalloproteinase inhibitors to treat or prevent inflammation. The present invention also includes compositions and methods to treat injury and disease related to such biological processes.

Abstract: The present invention identifies P-selectin as a modulator of hemostasis. Accordingly, the present invention relates to methods for the identification and use of modulators of P-selectin activity as modulators of hemostasis. The invention also relates to methods and compositions for the diagnosis and treatment of hemostatic disorders, including, but not limited to, hemorrhagic disorders and thrombotic disorders. The present invention describes methods for the diagnostic evaluation and prognosis of various hemostatic conditions, and for the identification of subjects exhibiting a predisposition to such conditions. In addition, the present invention provides methods for the diagnostic monitoring of patients undergoing clinical evaluation for the treatment of a hemostatic or vascular disorders, and for monitoring the efficacy of compounds in clinical trials.

Abstract: The present invention relates to compounds that are capable of modulating CD154 mobilization and that are useful for stabilizing the thrombotic process and reducing the activation of cells involved in an inflammatory response. The present invention also relates to methods useful for identifying such compounds. The present invention also relates to the treatment of platelets for transfusion with metalloproteinase inhibitors to treat or prevent inflammation. The present invention also includes compositions and methods to treat injury and disease related to such biological processes.

Abstract: The invention relates to a novel method for evaluating the antiproliferative activity of compounds having MetAP inhibitory activity, as well as a method for screening compounds that inhibit angiogenesis or growth of tumors. The invention additionally provides a method for monitoring the progress of treatment for controlling angiogenesis or the growth of tumors.

Abstract: The invention relates to compounds that are capable of modulating CD154 mobilization and that are useful for stabilizing the thrombotic and/or coagulation process and/or reducing the activation of cells involved in an inflammatory response. The invention also relates to methods useful for identifying such compounds. The invention also relates to the treatment of platelets for transfusion with metalloproteinase inhibitors to treat or prevent inflammation. The present invention also includes compositions and methods to treat injury and disease related to such biological processes.

Abstract: The present invention relates to compounds that are capable of modulating CD154 mobilization and that are useful for stabilizing the thrombotic process and reducing the activation of cells involved in an inflammatory response. The present invention also relates to methods useful for identifying such compounds. The present invention also relates to the treatment of platelets for transfusion with metalloproteinase inhibitors to treat or prevent inflammation. The present invention also includes compositions and methods to treat injury and disease related to such biological processes.

Abstract: The cardboard container is characterized in that it has folding panels (501 and 502) on substantially the same surface as the sidewalls (109 and 110), which are adapted to be disposed facing said sidewalls (109 and 110) parallel to them, and which are secured on the one hand to the closure panel (140) by one of their edges and on the other hand either to an adjacent wall (107-109-110) of the base (106), or to a securement flap (142) secured to the closure panel (140), or to both of these elements, by means of a bellows (503) formed from at least two tongues (504-505-506, 515-516) secured to each other by a bend line.

Abstract: The present invention identifies P-selectin as a modulator of hemostasis. Accordingly, the present invention relates to methods for the identification and use of modulators of P-selectin activity as modulators of hemostasis. The invention also relates to methods and compositions for the diagnosis and treatment of hemostatic disorders, including, but not limited to, hemorrhagic disorders and thrombotic disorders. The present invention describes methods for the diagnostic evaluation and prognosis of various hemostatic conditions, and for the identification of subjects exhibiting a predisposition to such conditions. In addition, the present invention provides methods for the diagnostic monitoring of patients undergoing clinical evaluation for the treatment of a hemostatic or vascular disorders, and for monitoring the efficacy of compounds in clinical trials.

Abstract: This invention discloses a radiation curable coating composition which is comprised of (1) a crosslinked polymeric resin which is comprised of repeat units which are derived from (a) at least one member selected from the group consisting of acrylate monomers and vinyl aromatic monomers and (b) a crosslinking monomer; (2) an acrylate diluting monomer; and (3) a photocatalyst.

Abstract: A ball nose end mill includes two identical cutting inserts which are clamped into two dissimilar insert seats. Each one of the two insert seats includes a narrower end and a wider end, the narrower end of one insert seat being located at the tip of the end mill, while the narrower end of the other insert seat is located at the end of the insert seat distal to the tip of the end mill. The inserts are correspondingly shaped with a wider end a narrower end, the ends being curved, and with rectilinear longitudinal sides. The inserts may be inclined axially negatively. The ball nose end mill permits two identical inserts to be used, permits large cutting depths to be obtained, and a negative axial inclination permits an impact point that is distanced from the tool tip.

Abstract: A known thermal actuator includes a capsule, which contains a diaphragm controlling the position of a stem. A thermal expansion substance like wax is contained in the capsule which operates as a thermostat in a thermostatically controlled valve such as a thermostatically controlled mixing valve. The stem of the actuator is connected with a valve body movable between two valve seats for a hot and cold medium, respectively, and the capsule is placed in the area of the mixed medium for transmitting the heat of the mixed medium to the thermal expansion substance. In order to present a simple and more effective actuator that can react promptly at changes of temperature and which does not require an extra temperature sensor, the capsule includes an oblong cuplike sensor body, the surface of which is at least partly deformed in such a way that its thermal transmittance area is increased.

Abstract: A multichamber container must have certain characteristics in order to uniformly dispense the contents of each chamber from the container. The outer wall of the container and the inner divider web walls must have certain characteristics. The inner divider web walls must be highly flexible while the outer container wall must be less flexible. The Deflective Force for the outer wall must be greater than the Deflective Force for the web walls. In addition, to alleviate the problem of suckback of air into the container chambers, the outer wall should exhibit a specific Retention Index. This is a measure of the outer wall to remain deflected after the removal of the deflecting force. The inner divider web wall will have a lower Retention Index than the outer wall. By the proper selection of outer wall and web walls, there can be uniform dispensing from the dispenser. The Stiffness of the outer wall also should be less than the Stiffness for the inner web divider walls.

Abstract: A multichamber container such as a multichamber tube or multichamber pump can deliver the contained products in varying arrays by the use of container shoulders of different channel configurations. The container body remains the same with chamber dividing walls extending from the container base to the container shoulder. The container shoulder attachment to the container walls and to the chamber dividing walls can remain essentially the same. Within the shoulder, channels direct the flow of each product so that it has a number of arrays from an A/B/A sandwich to axial arrays to semiconcentric arrays to fully concentric arrays. The channels that are a part of the shoulder will direct the product from each chamber to be dispensed in a single stream or multiple streams. Also, the streams can be shaped to many different shapes by the shape and the arrangement of the channels in the shoulder.