Abstract: Vascular access devices and methods of their use are provided. In one embodiment, a vascular access device includes a catheter (112) and at least one deployable wire (134). The catheter includes a primary lumen extending from a proximal end to a distal end of the catheter. The at least one deployable wire is secured to the catheter and configured to move relative to the catheter between a delivery configuration and a deployed configuration.

Abstract: A method of locating a substrate within a field of view of an imaging system includes acquiring an image of a first marker on a substrate in the field of view. The first marker has a first spatial pattern representing a position of the first marker relative to the substrate. The method also includes determining possible positions of the substrate based on the first spatial pattern and moving the substrate relative to the field of view based on the possible positions of the substrate. The method also includes acquiring an image of a second marker on the substrate in the field of view. The second marker has a second pattern representing a position of the second marker relative to the substrate. The method further includes determining the position of the substrate relative to the field of view based on the position of the second marker on the substrate.

Abstract: Formulations and methods are disclosed for the harvesting and subsequent passaging of human pluripotent stem cells without the use of enzymes and/or scraping to dislodge cells from cell culture vessels. The formulations and methods permit the harvesting of cells as large clusters from the surface of various cell culture vessels including multilayer cell culture vessels. Further, the formulations and methods provide high yields of harvested cells for subsequent passaging and high post-harvest cell viability. Pluripotent stem cells passaged with the formulations according to the methods remain undifferentiated and express typical stem cell markers, while, at the same time, they retain the differentiation capability and arc able to differentiate into the cells in all three germ layers and generate teratomas, even after numerous rounds of harvesting and passaging. These hPSCs also maintain normal karyotype after passaged with the formulations for extended period of time.

Abstract: A venue recommendation and alert system is disclosed for receiving vehicle attribute information, analyzing the vehicle attribute information, determining a recommended venue for listing the vehicle, presenting the recommended venue to a user, and alerting the user of any changes to the recommendation based on new information.

Abstract: A tubular duct member comprises a plurality of sheet metal panels 10, 12 joined along adjacent longitudinal edges by cooperating folded sheet metal catches 14, 16, the catches being pushed together such that respective detent surfaces 28, 30 on each catch engage behind one another to retain the edges of the sheets together. One of the catches 14 includes a body 36 of resilient material compressed between the catches and biasing the catches apart to maintain the detent surfaces 28, 30 bearing against one another.

Abstract: In an aspect, a neurological data collecting apparatus is described. A plurality of electronically interconnected interface panels configured to selectively display stimuli and accept input is provided. An interface panel frame supports the plurality of interface panels and aggregates the plurality of interface panels into a user interface screen 6 that extends into the user's peripheral vision when the user is standing within a predetermined distance from the user interface screen. A supporting stand is connected to the user interface screen. The supporting stand includes a height adjustment mechanism for adjusting the height of the user interface screen to eye level of the user. A control unit electronically connects the user interface screen to a computer.

Abstract: Formulations and methods are disclosed for the harvesting and subsequent passaging of human pluripotent stem cells without the use of enzymes and/or scraping to dislodge cells from cell culture vessels. The formulations and methods permit the harvesting of cells as large clusters from the surface of various cell culture vessels including multilayer cell culture vessels. Further, the formulations and methods provide high yields of harvested cells for subsequent passaging and high post-harvest cell viability. Pluripotent stem cells passaged with the formulations according to the methods remain undifferentiated and express typical stem cell markers, while, at the same time, they retain the differentiation capability and are able to differentiate into the cells in all three germ layers and generate teratomas, even after numerous rounds of harvesting and passaging. These hPSCs also maintain normal karyo-type after passaged with the formulations for extended period of time.

Abstract: Apparatus and methods for converting one type of speech processor unit into another type of speech processor unit.

Abstract: Apparatus and methods for converting one type of speech processor unit into another type of speech processor unit.

Abstract: A method of operating a gas turbine engine (20) comprising a variable geometry compressor (24), a variable geometry combustor (28), and a variable geometry turbine (30). The method comprises operating the variable geometry combustor (28) such that a corrected flow ?c through a combustion zone (46, 48) of the combustor (28) matches a predetermined value.

Abstract: Disclosed herein are schemes for the synthesis of novel hydrogen-bonded rare earth-BINOLate precatalyst complexes, the precatalysts, per se, and their application for the generation of anhydrous REMB catalysts by cation-exchange from metal halides.

Abstract: Apparatus and methods for converting one type of speech processor unit into another type of speech processor unit.

Abstract: A gas turbine engine (20) comprising a variable geometry engine compressor (24), a variable geometry engine turbine (30) coupled to the engine compressor (24) and a combustor (28). The combustor (28) has an inlet (34) arranged to receive air from a first engine compressor outlet (34), and an outlet arranged to deliver combustion products to the engine turbine (30); a combustor bypass passage (50) having an inlet (53) arranged to receive air from a second engine compressor outlet (53), and an outlet (54) in fluid communication with a main fluid flow path downstream of a combustion zone (46, 48) of the combustor (28), and upstream of a turbine inlet (31); wherein the combustor bypass passage (50) comprises a bypass control valve (52) configured to selectively modulate the ratio of air flowing to the combustor inlet (34) to air flowing through the bypass passage (50).

Abstract: Apparatus and methods for converting one type of speech processor unit into another type of speech processor unit.

Abstract: A process for producing L(+) lactic acid in high enatiopurity from lignocellulosic material which includes providing a hydrolysate of cellulose polymers prepared from said lignocellulosic material and comprising hexose and pentose sugars and contacting said hydrolysate with the bacterium Bacillus coagulans (ATCC 23498) strain designation M-39 in a fermentation reaction.

Abstract: A process for producing D(-) lactic acid in high enatiopurity from lignocellulosic material includes providing a hydrolysate of cellulose polymers prepared from the lignocellulosic material, which includes hexose and pentose sugars and contacting the hydrolysate with the bacterium Lactobacillus coryniformis subsp. Torquens, strain 30 (ATCC 25600) in a fermentation reaction.

Abstract: Described herein are methods for enhancing the nuclear reprogramming of somatic cells to become induced pluripotent stem cells. In particular, the methods disclosed herein involve the use of damage-associated molecular pattern molecules (DAMP). In certain embodiments the DAMPs are aluminum compositions such as aluminum hydroxide. Such DAMPs have unexpectedly and surprisingly been found to enhance the nuclear reprogramming efficiency of the reprogramming factors commonly used to induce somatic cells to become induced pluripotent stem cells. Accordingly, this disclosure describes methods of nuclear reprogramming as well as cells obtained from such methods along with therapeutic methods for using such cells for the treatment of disease amendable to treatment by stem cell therapy; as well as kits for such uses.

Abstract: Formulations and methods are disclosed for the harvesting and subsequent passaging of human pluripotent stem cells without the use of enzymes and/or scraping to dislodge cells from cell culture vessels. The formulations and methods permit the harvesting of cells as large clusters from the surface of various cell culture vessels including multilayer cell culture vessels. Further, the formulations and methods provide high yields of harvested cells for subsequent passaging and high post-harvest cell viability. Pluripotent stem cells passaged with the formulations according to the methods remain undifferentiated and express typical stem cell markers, while, at the same time, they retain the differentiation capability and are able to differentiate into the cells in all three germ layers and generate teratomas, even after numerous rounds of harvesting and passaging. These hPSCs also maintain normal karyo-type after passaged with the formulations for extended period of time.

Abstract: Apparatus and methods for converting one type of speech processor unit into another type of speech processor unit.