Abstract: A method includes: determining that at least one cylinder of a first cylinder bank of an engine is active; determining that at least one cylinder of a second cylinder bank of the engine is inactive; receiving an inlet temperature of a selective catalytic reduction system; comparing the inlet temperature to a temperature setpoint; and adjusting at least one of a first exhaust manifold pressure setpoint for the first cylinder bank or a second exhaust manifold pressure setpoint for the second cylinder bank based on the comparison.

Abstract: A stringed musical instrument saddle containing a plurality of electrically independent transducers and associated electrical conditioning components where each transducer is located within the saddle such that it is sensitive to the vibratory energy of a corresponding string or course and senses the vibratory energy in both vertical and horizontal modes. The saddle contains at least one multi-conductor connector which connects to a removable multi-conductor cable to convey the transducer signals out of the saddle to external receiving electronics. The saddle is constructed of workable materials such that its top and bottom can be fit to a particular instrument by a technician.

Abstract: A door closer, including: an anchor assembly, including: a frame mounting plate which is fixable relative to a door frame; and an adjustor plate; and an actuator assembly for mounting within the thickness of a door leaf to move the door leaf between open and closed configurations relative to the door frame, the actuator assembly including an operating member coupled by a link to the adjustor plate and mounted for a range of movements between a fully retracted position, in which the anchor assembly is held adjacent the actuator assembly when the door leaf is in the closed configuration, and an extended position, in which the anchor assembly is in spaced relation to the actuator assembly when the door leaf is in the open configuration, the link being configured to extend from the adjustor plate along a first axis, wherein the frame mounting plate is provided with one or more slot(s), the or each slot being elongated along a second axis, the second axis being generally orthogonal to the first axis.

Abstract: Methods, systems, and devices for automatically customizing operation of a robotic vehicle are described. The method may include identifying an operator, retrieving an operator profile and associated metadata for the operator from a database, where the metadata includes operator habit information, and configuring the robotic vehicle based on existing preference-based and performance-based settings, where the existing preference-based and performance-based settings are based on the metadata. The methods may include identifying operator habit information during operation of the robotic vehicle, deriving updated preference-based and performance-based settings for the operator based on the identified operator habit information, and providing, to the database, modifications to the metadata associated with the operator profile of the operator.

Abstract: Example electrosurgical devices and systems are disclosed. An example electrosurgical device includes a body, an electrosurgical electrode secured to the body, the electrosurgical electrode including a distal tip. The electrosurgical device also includes a shroud translatable relative to the electrosurgical electrode between a first position and a second position, a first magnetic component which is operably connected to the body, and a second magnetic component which is operably connected to the shroud, wherein the first and second magnetic components magnetically interact to releasably maintain the shroud in the first position.

Abstract: The present disclosure provides engineered polynucleotide sequences that form scaffolds and nucleoprotein complexes comprising such engineered polynucleotide sequences that form scaffolds and nucleic acid binding proteins. Nucleic acid sequences encoding the engineered polynucleotide sequences that form scaffolds, as well as expression cassettes, vectors and cells comprising such polynucleotide sequences, are described. A variety of methods for making and using the engineered polynucleotide sequences that form scaffolds are also disclosed.

Abstract: A method includes receiving an execute packet that includes a first instruction and a second instruction and executing the first instruction and the second instruction using a pipeline. Executing the first and second instructions includes storing a result of the first instruction in a holding register; determining whether an event that interrupts execution of the execute packet occurs prior to completion of the executing of the second instruction; and based on the event not occurring, committing the result of the first instruction after completion of the executing of the second instruction.

Abstract: A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, a needle insertion mechanism, a fluid flow connection, and a valve in fluid communication with the fluid flow connection and the needle insertion mechanism. The container has an inner volume to contain a medicament which is urged out of the container by the activation mechanism. The needle insertion mechanism is adapted to insert a needle and/or a cannula to deliver the medicament from the container via the fluid flow connection. The valve is in fluid communication with the fluid flow connection and needle insertion mechanism, and is movable between first and second positions. Upon insertion of the needle and/or the cannula, the valve remains in the first position whereby fluid flow is restricted. At a later time, the valve is urged to the second position whereby fluid may flow through the needle or cannula.

Abstract: A solar module mounting bracket system including a plurality of solar modules including mounting slots formed in a sidewall of the solar module, a torque tube configured to support the solar modules such that they can be rotated, a plurality of mounting brackets configured for integration with the torque tube and to which the plurality of solar modules are mounted, at least one first retainer assembly connected to one of the plurality of mounting brackets, the first retainer assembly including a through bolt, a spring, a mounting tab, and nut. When a solar module is placed on the mounting bracket and supported by the torque tube the mounting tab retainer assembly is received in the mounting slot of the solar module.

Abstract: A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, and a needle insertion mechanism (NIM). The container has an inner volume to contain a medicament which is urged out of the container by the activation mechanism. The needle insertion mechanism (NIM) is operably coupled with the activation mechanism and includes an actuation assembly adapted to insert a needle and a cannula to deliver the medicament from the container. The actuation assembly is movable between a storage state, a first operational state, a second operational state, and a third operational state to selectively position the needle and the cannula.

Abstract: The present disclosure provides polynucleotide guides for use in CRISPR-Cas systems wherein such polynucleotides contain at least one CRISPR abasic restricted nucleotide (CABRNT) and/or at least one CRISPR accuracy via analogs (CAVA) nucleotide. CRISPR guides that contain at least one abasic site and/or at least one base analog, as well as nucleoprotein complexes of CRISPR-Cas proteins and CABRNT, CAVA, and CABRNT-CAVA guides are also described. Also disclosed are methods for making and using the CABRNT, CAVA, and CABRNT-CAVA polynucleotides and guides and the CABRNT/Cas, CAVA/Cas, and CABRNT-CAVA/Cas nucleoprotein complexes of the present invention.

Abstract: An adaptor includes a body defining a longitudinal axis, and a transverse axis that is normal to the longitudinal axis. The body also has a leading portion defining a lock receiving recess extending transversely at least partially through the leading portion. The leading portion defines at least one linear portion in the lock receiving recess that is configured to engage the power locking device.

Abstract: Systems, methods, and apparatuses are provided for increasing exhaust gas temperature. A system includes a valve and a controller coupled to the valve. The controller is structured to determine that a plurality of cylinders of an engine are active; compare an exhaust aftertreatment temperature to an exhaust aftertreatment temperature setpoint; and in response to the comparison, adjust an effective flow area for exhaust gas from the plurality of cylinders of the engine to increase an exhaust gas temperature.

Abstract: Disclosed is a method for converting cymene generated from renewable low value terpene streams into renewable benzene, toluene, xylenes, and cymene isomers (ortho and meta) under flow disproportionation reaction conditions, which compounds are basic building blocks for fragrance materials. This technology has potential to replace high volume petrochemical-based feedstocks with plant-based building blocks that can fill the renewability gap for key fragrance ingredients.

Abstract: The present disclosure provides DNA-guided CRISPR systems; polynucleotides comprising DNA, RNA and mixtures thereof for use with CRISPR systems; and methods of use involving such polynucleotides and DNA-guided CRISPR systems.

Abstract: Methods, devices and systems enable controlling an autonomous vehicle by identifying a vehicle that is within a threshold distance of the autonomous vehicle, determining an autonomous capability metric (ACM) the identified vehicle, determining whether the ACM of the identified vehicle is greater than a first threshold, determining whether the ACM of the identified vehicle is less than a second threshold, and adjusting a driving parameter of the autonomous vehicle so that the autonomous vehicle is more or less reliant on the capabilities of the identified vehicle based on whether the ACM of the identified vehicle exceeds the thresholds.

Abstract: Various embodiments include methods and interactive traffic control devices for interactively controlling traffic, which may include receiving refined location and state information associated with individual vehicles on a roadway, and determining customized dynamic traffic control instructions for a first one or more of the individual vehicles. The determined customized dynamic traffic control instructions may be based on the received refined location and state information and offer an optional route alternative to a set limited number of the individual vehicles. The first customized dynamic traffic control instructions may be transmitted by the interactive traffic control device to the first one or more of the individual vehicles.

Abstract: A battery cell stack casing includes casing walls defining a housing interior for receiving a battery cell stack; a first end plate provided between the walls at a first end of the casing to close a first end of the housing interior. The casing also include a second end plate provided between the walls at a second end of the casing to close a second end of the housing interior. The casing walls have a multi-layer structure include: an inner layer having a first side facing into the housing interior and a second opposite side; an outer layer spaced outwardly from the second side of the inner layer; a thermally insulating volume defined between the second side of the inner layer and the outer layer, the thermally insulating material containing a low density thermally insulative material e.g., foam or other insulative material; and a layer of intumescent material provided on the first side of the inner layer.

Abstract: A battery cell stack casing includes casing walls defining a housing interior for receiving a battery cell stack, a first end plate provided between the walls at a first end of the casing to close a first end of the housing interior, and a second end plate provided between the walls at a second end of the casing to close a second end of the housing interior. The casing walls have a multi-layer structure that includes, an inner layer having a first side facing into the housing interior and a second opposite side, an outer layer spaced outwardly from the second side of the inner layer, an air or vacuum-filled thermally insulating volume defined between the second side of the inner layer and the outer layer, and a layer of intumescent material provided on the first side of the inner layer.