Patents by Inventor Paul Edwards

Paul Edwards has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10526639
    Abstract: The present invention relates to the field of analysis of the three-dimensional structure of the genome, i.e., for genome architecture mapping (GAM). The invention provides a method of determining spatial proximity of a plurality of nucleic acid loci in a compartment such as the cell nucleus, by exploiting their co-segregation amongst fractions of that compartment, identified upon separation of the nucleic acid loci from each other depending on their localization in the compartment to obtain a collection of fractions, e.g., by cryo-sectioning or cryo-milling the compartment; determining the presence or absence of the plurality of loci in the fractions; and determining the co-segregation of the plurality of loci. Co-segregation may then be analysed with statistical methods to determine spatial proximity. The method can be used e.g., for determining physical distance between a plurality of loci; and mapping loci and/or genome architecture, e.g.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: January 7, 2020
    Assignees: MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT, CAMBRIDGE ENTERPRISE LTD.
    Inventors: Ana Pombo, Paul Edwards, Mario Nicodemi, Antonio Scialdone, Robert Beagrie
  • Patent number: 10531598
    Abstract: Method for and apparatus were fans and cable placed at the ends at the same end of a computer rack drawer. The cable ends are located between the fans and the computing elements. The bulk length of each cable passes through the region where the fans are located. Air, and optionally EMI, sealing are provided by an elastic material near the fans. In this way cables could exit the same tailstock of the drawer where fans are located. The cable ends can receive good cooling, and the distance between the cable ends and computing elements of the drawer is not lengthened by the fan position.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: January 7, 2020
    Assignee: International Business Machines Corporation
    Inventors: Paul W. Coteus, Todd Edward Takken, Shurong Tian, Yuan Yao, Lisha Zhang
  • Publication number: 20200000169
    Abstract: A garment worn by a wearer has an exterior shell and an interior shell with various impact absorbing material between the exterior shell and the interior shell. The impact absorbing material includes multiple structures, such as rods or filaments, capable of deforming when force is applied then returning to its state prior to application of the force. In various embodiments, a rate sensitive material (RSM) is positioned in one or more locations relative to the exterior shell and the interior shell of the garment to further attenuate impacts to the garment. The RSM changes its resistance to force based on a rate at which the material is loaded.
    Type: Application
    Filed: September 13, 2019
    Publication date: January 2, 2020
    Inventors: Per Reinhall, Paul C. Leonard, Travis Edward Glover, Andre Hunter Paggao Stone, Anton Perry Alferness, Kurt V. Fischer, Gary S. Kaplan, John T. Dardis, II, Samuel R. Browd
  • Publication number: 20200002950
    Abstract: A roof vent is made from convoluted filaments. The roof vent includes a center section, a first end section, and a second end section, all made from convoluted filaments. The first and second end sections each include a top layer made from convoluted filaments and a bottom layer made from convoluted filaments. The thickness of the first end section may be substantially the same as a thickness of the center section. A filter may cover the top of the center section, the tops, ends, sides, and bottoms of the first and second end sections, and a portion of a bottom of the center section, leaving a middle portion of the bottom of the center section uncovered by the filter.
    Type: Application
    Filed: August 20, 2019
    Publication date: January 2, 2020
    Inventors: Paul Edward Gassman, Jeffrey Wayne Smith, Jay D. Wagner
  • Publication number: 20200002609
    Abstract: A method of enhancing soil water infiltration (SWI) and/or reducing soil water repellency (SWR) comprising: treating an area of groundcover with a composition A comprising A1) a block polymer (P) comprising at least one polyethyleneoxide moiety and at least one polypropyleneoxide moiety, and A2) an alcohol alkoxylate (E), wherein the SWI of the area of groundcover is enhanced and/or the SWR of the area of groundcover is reduced after treatment with the composition A.
    Type: Application
    Filed: February 2, 2018
    Publication date: January 2, 2020
    Inventors: David Edward MAINWARING, Pandiyan MURUGARAJ, Rohan DAVIES, Paul KLINGELHOEFER, Alexander WISSEMEIER
  • Patent number: 10522050
    Abstract: An optimization engine builds a set of test forms, called a pallet for use in a qualification test setting. The pallet is generated using a optimization engine programmed with constraints and goals for each test form in the pallet and for the pallet in general. A test information floor is set at the cut point of the test which causes test items to be focused at the area of the test where the pass/fail decision is made. Further constraints may be programmed to maximize the item diversity, that is, to spread the use of available test items as uniformly as possible.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: December 31, 2019
    Assignee: National Assoc. of Boards of Pharmacy
    Inventors: Paul Edward Jones, Joy Lynn Matthews-López
  • Patent number: 10517874
    Abstract: Compounds of Formulae I? and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: December 31, 2019
    Assignee: Cyclerion Therapeutics, Inc.
    Inventors: Takashi Nakai, Joel Moore, Nicholas Robert Perl, Rajesh R. Iyengar, Ara Mermerian, G-Yoon Jamie Im, Thomas Wai-Ho Lee, Colleen Hudson, Glen Robert Rennie, Paul Allan Renhowe, Timothy Claude Barden, Xiang Y. Yu, James Edward Sheppeck, Karthik Iyer, Joon Jung, George Todd Milne, Kimberly Kafadar Long, Mark G. Currie, James Jia
  • Patent number: 10518196
    Abstract: A separation device, system and associated method are provided herein for separation of particulates form a base fluid. The separation device comprises a first microchannel comprising a fluid inlet and a mesofluidic collection chamber. The mesofluidic collection chamber has a first side and a second side, wherein the mesofluidic collection chamber is operatively coupled to the first microchannel on the first side, and wherein the mesofluidic collection chamber comprises a first fluid outlet at the second side, such that the fluid inlet, first microchannel, and first fluid outlet are in fluidic communication via the mesofluidic collection chamber.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: December 31, 2019
    Assignee: General Electric Company
    Inventors: Christopher Michael Puleo, Craig Patrick Galligan, Gregory Andrew Grossman, Erik Leeming Kvam, Robert Scott Duthie, Kenneth Wayne Rigby, Paul Michael Smigelski, Jr., Victoria Eugenia Cotero, Jason William Castle, John Donald Burczak, James Edward Rothman
  • Patent number: 10507164
    Abstract: A coated glass container having a Type 1 chemical durability according to USP 660 (2011), a class A2 base resistance or better according to ISO 695, and a type HGB2 hydrolytic resistance or better according to ISO 719. The glass body having an interior surface and an exterior surface. A lubricous coating having a thickness of <100 microns positioned on the exterior surface. The portion of the exterior surface with the coating having a coefficient of friction that is at least 20% less than an uncoated glass container formed from the same glass composition and does not increase by more than 30% after undergoing depyrogenation at about 260° C. for 30 minutes. A horizontal compression strength of the coated glass container is at least 10% greater than an uncoated glass container formed from the same glass composition and is not reduced by more than 20% after heat treatment at about 260° C. for 30 minutes.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: December 17, 2019
    Assignee: CORNING INCORPORATED
    Inventors: Theresa Chang, Paul Stephen Danielson, Steven Edward DeMartino, Andrei Gennadyevich Fadeev, Robert Michael Morena, Santona Pal, John Stephen Peanasky, Robert Anthony Schaut, Christopher Lee Timmons, Natesan Venkataraman, Ronald Luce Verkleeren
  • Publication number: 20190375594
    Abstract: Described in detail herein is object storage and retrieval system. Each of multiple storage towers can store and dispense physical objects. The storage towers can be an octagonal prism-shaped housing, a shelving unit disposed within the housing, and one or more receptacles defining one or more openings in the housing. A loader disposed in the housing of each storage tower, can transfer one or more of the physical objects between the one or more receptacles and shelves of the shelving unit. An intermediate transport apparatus disposed external to the storage towers and positioned between two or more of the storage towers, can be aligned with one of the one or more receptacles of each of the two or more storage towers. The intermediate transport apparatus can transfer the one or more physical objects between the two or more towers via the one or more receptacle.
    Type: Application
    Filed: June 6, 2019
    Publication date: December 12, 2019
    Inventors: David G. Tovey, Paul Edward Durkee, Kurt William Robert Bessel
  • Patent number: 10500789
    Abstract: A system for de-powdering one or more objects within a powder print bed comprises a build box configured to contain the powder print bed, and a de-powdering subsystem configured to engage the build box. The de-powdering subsystem comprises a vacuum device configured to withdraw loose powder agitated by the air jet device, and a robotic arm configured to convey the vacuum device to one or more locations on the powder print bed. The system may further comprise an air jet device disposed on the robotic arm, the air jet device configured to agitate, with a jet of air, unbound powder within the powder print bed. The system may further comprise a mechanical agitation instrument configured to facilitate agitation of the unbound powder within the powder print bed. The mechanical agitation instrument may be used in conjunction with one or both of the vacuum device and the air jet device.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: December 10, 2019
    Assignee: Desktop Metal, Inc.
    Inventors: Ricardo Fulop, Robert Michael Shydo, Jr., Jonah Samuel Myerberg, Charles Edward Martin, Justin Cumming, Paul Hoisington, Emanuel M. Sachs
  • Patent number: 10494965
    Abstract: Various methods and systems are provided for an oil filter system for a vehicle system. In one example, an oil filter system comprises a housing within which a plurality of oil filter elements are disposed and a frame supporting the housing, the frame including one or more mountings configured to support one or more vehicle sub-assemblies.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: December 3, 2019
    Assignee: GE Global Sourcing LLC
    Inventors: Paul John Fontecchio, Gregory Alan Marsh, Mark Thomas Zysk, Paul James Wadding, Michael Edward Keverline
  • Patent number: 10493594
    Abstract: A peening device for treating a component includes a shot media propulsion source configured to propel a quantity of shot media. The device also includes a plurality of treatment enclosures each selectively coupleable to the shot media propulsion source. Each of the treatment enclosures has a shape complementary to a corresponding one of a plurality of portions of the component, such that each treatment enclosure and the corresponding portion cooperate to enclose the shot media.
    Type: Grant
    Filed: April 12, 2016
    Date of Patent: December 3, 2019
    Assignee: General Electric Company
    Inventors: Michael Ericson Friedman, Colin Beckwith Spellmeyer, Bryan Edward Williams, Paul Lawrence Kalmar
  • Patent number: 10496878
    Abstract: An information processing apparatus, comprising: receiver circuitry configured to receive i) a video stream comprising a plurality of images, each image containing at least one object located at a position in a plane and the image having associated image timing information indicating its temporal position in the video stream and ii) a stream of object tracking information each having associated object timing information indicating its temporal position in the stream of object tracking information wherein the stream of object tracking information corresponds to the video stream and separately defines the position of the object in the plane captured in each image in the video stream; and controller circuitry configured to perform pattern matching on the position of each of the objects in the video stream and the object tracking information, and when there is a closest matching position, synchronising the image timing information and the object timing information.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: December 3, 2019
    Assignee: Sony Corporation
    Inventors: Michael John Williams, William Jack Leathers-Smith, Paul Edward Prayle
  • Publication number: 20190359692
    Abstract: A p38 MAPK inhibitor for use in the treatment or prevention of severe influenza in a human patient. In some embodiments, the severe influenza maybe characterised by hypercytokinemia involving elevated levels of one or more pro-inflammatory cytokines. The p38 MAP kinase inhibitor may act to inhibit the release of such pro-inflammatory mediators from endothelial cells. In some embodiments, the p38 MAP kinase inhibitor may inhibit the release of IP 10 from endothelial cells, preferably in a dose-dependent manner.
    Type: Application
    Filed: June 26, 2017
    Publication date: November 28, 2019
    Applicant: HVIVO SERVICES LIMITED
    Inventors: Paul Andrew Whittaker, Neil Edward Torbett
  • Patent number: 10487633
    Abstract: A system for producing hydrocarbons from a subterranean well including a wellbore extending from a surface into a subterranean formation includes a wellhead disposed at the surface. In addition, the system includes a production tree coupled to the wellhead and a casing coupled to the wellhead and extending into the wellbore. Still further, the system includes a first production tubing string extending into the casing from the wellhead to a first production zone and a second production tubing string extending into the casing from the wellhead to the first production zone. The first production tubing string and the second production tubing string are each configured to provide a fluid flow path for gases from the first production zone. The second production tubing string is radially spaced from the first production tubing string. The first production tubing string has an inner diameter D1 that is larger than an inner diameter D2 of the second production tubing string.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: November 26, 2019
    Assignee: BP Corporation North America Inc.
    Inventors: Michael Elgie Aman, Paul A. Edwards, Timothy Idstein
  • Patent number: 10486549
    Abstract: A vehicle system includes a camera and a display device. The camera is configured to capture an image and the display device is programmed to display the image. Each image includes a target, and the display device displays a virtual overlay on the image. The virtual overlay is displayed on the display device at a fixed location.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: November 26, 2019
    Assignee: FORD GLOBAL TECHNOLOGIES, LLC
    Inventors: Brad Alan Ignaczak, Ali Hassani, Adil Nizam Siddiqui, Paul Theodosis, Christopher W. Bell, Thomas Edward Pilutti, Brian Bennie
  • Publication number: 20190357282
    Abstract: Concepts and technologies disclosed herein are directed to session continuity between software-defined network (“SDN”) controlled and non-SDN controlled wireless networks. In one embodiment, an SDN controller can determine that a handover of a user equipment (“UE”) from a base station operating under control of the SDN-controlled network to a further base station operating under control of a non-SDN-controlled network has occurred. The SDN controller can establish over an interface between the SDN controller and a packet gateway (“P-GW”), a tunnel through which to exchange handover data associated with the handover and a session IP address for a session in which the UE is involved. The SDN controller can provide, over the interface and through the tunnel, the handover data and the session IP address to the P-GW.
    Type: Application
    Filed: August 5, 2019
    Publication date: November 21, 2019
    Applicant: AT&T Intellectual Property I, L.P.
    Inventors: Zhi Cui, Paul Edward Smith, JR., Sangar Dowlatkhah
  • Patent number: 10483870
    Abstract: A power conversion method comprising: charging a plurality of energy storage devices of a power converter from an input power source; and sequentially coupling and decoupling energy storage devices of the plurality of energy storage devices to an output. Charging the plurality of energy storage devices comprises maintaining at least two of the plurality of energy storage devices at substantially different potentials.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: November 19, 2019
    Assignee: Offshore Renewable Energy Catapult
    Inventors: Chong Hwa Ng, Paul McKeever, Michael Edward Smailes
  • Patent number: 10479802
    Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: November 19, 2019
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Samuel Coe, Jonathan Bard, Peter David Johnson, Michael Edward Prime, Christopher John Brown, Sébastien René Gabriel Galan, Paul Richard Giles, Elise Luciennen Paulette Gadouleau, Thomas Martin Krülle, Daniel Clark-Frew, John Wityak, Alex Kiselyov, Sarah Hayes