Abstract: Pharmaceutical formulations comprising solid pharmaceutically acceptable organic acids, such as maleic acid or tartaric acid, that inhibit the disproportionation of pharmaceutically acceptable acid salts of active pharmaceutical ingredients, and methods of manufacturing such pharmaceutical compositions. The pharmaceutically acceptable acid salt of the active pharmaceutical ingredient has a pKa of less than about 6.0, and wherein the solid pharmaceutically acceptable organic acid has a pKa of less than about 4.0 and an aqueous solubility in the range of about 500 to about 2000 milligrams per milliliter. A pharmaceutical formulation comprising a pharmaceutical acceptable acid salt of pioglitazone, a solid pharmaceutically acceptable organic acid selected from the group consisting of maleic acid or tartaric acid, and an excipient that promotes disproportionation, wherein the ratio by weight of the solid pharmaceutically acceptable organic acid to excipient is from about 1:6 to about 1:1.

Abstract: Optical inks suitable for 3D printing fabrication of gradient refractive index (GRIN) optical components are composed of a monomer matrix material [100] in which ligand-functionalized nanoparticles [102] are well dispersed at more than 2% loading to induce a change in the index of refraction of the matrix of at least 0.02. The ligands are less than 1.2 nm in length and are covalently bonded to both the nanoparticles and the monomer matrix. The nanoparticles are less than 100 nm in size and the doped matrix material has a transmittance of at least 90% at wavelengths of interest. The matrix material has less than 20 cPoise viscosity and is UV crosslinkable to form a cured polymer.

Abstract: Gradient Refractive Index (GRIN) optical materials [100] composed of a polymer matrix doped with functionalized nanocrystals realize high values for Vgrin, and hence nearly uniform focal lengths regardless of the wavelength of light. GRIN optical materials having low Vgrin magnitudes less than 10 are also provided.

Abstract: The present invention is directed to a pharmaceutical composition comprising the compound suvorexant, or a pharmaceutically acceptable salt thereof, a concentration-enhancing polymer, and optionally a pharmaceutically acceptable surfactant. The concentration-enhancing polymer is a polymer that forms an amorphous dispersion with suvorexant, that is insoluble or almost completely insoluble in water by (a) dissolving the suvorexant or (b) interacting with the suvorexant in such a way that the suvorexant does not form crystals or crystalline domains in the polymer. A concentration-enhancing polymer is water soluble or readily disperse in water, so that when the polymer is placed in water or an aqueous environment (e.g. fluids in the gastrointestinal (GI) tract or simulated GI fluids), the solubility and/or bioavailability of suvorexant is increased over the solubility or bioavailability in the absence of the polymer.

Abstract: Embodiments of the present invention recite a data collector with expanded functionality and a method of enhancing revenue generation using a data collector with expanded functionality. In one embodiment, a central unit of a data collector is configured to receive a replaceable unit such that any one of a variety of replaceable units can be configure to be attached to said central unit.

Abstract: Pharmaceutical formulations comprising solid pharmaceutically acceptable organic acids, such as maleic acid or tartaric acid, that inhibit the disproportionation of pharmaceutically acceptable acid salts of active pharmaceutical ingredients, and methods of manufacturing such pharmaceutical compositions. The pharmaceutically acceptable acid salt of the active pharmaceutical ingredient has a pKa of less than about 6.0, and wherein the solid pharmaceutically acceptable organic acid has a pKa of less than about 4.0 and an aqueous solubility in the range of about 500 to about 2000 milligrams per milliliter. A pharmaceutical formulation comprising a pharmaceutical acceptable acid salt of pioglitazone, a solid pharmaceutically acceptable organic acid selected from the group consisting of maleic acid or tartaric acid, and an excipient that promotes disproportionation, wherein the ratio by weight of the solid pharmaceutically acceptable organic acid to excipient is from about 1:6 to about 1:1.

Abstract: Embodiments of the present invention recite a method and system for displaying data on a portable electronic device. In one embodiment, a first portion of accessed data is displayed on a portable electronic device. A motion detector responsive to motion in at least a single direction then detects a movement of the portable electronic device from a first position to a second position. In response to the motion detector detecting the movement, a second portion of the accessed data is automatically displayed by the portable electronic device.

Abstract: A mass storage device includes a probe that has a cantilever having a first end region operatively connected to a substrate and a second end region rotated in a direction such that the second end region is opposed to the first end region. A tip is disposed on the second end region, with the tip pointing in a direction opposed to the first end region.

Abstract: Embodiments of the present invention recite a data collector with expanded functionality and a method of enhancing revenue generation using a data collector with expanded functionality. In one embodiment, a central unit of a data collector is configured to receive a replaceable unit such that any one of a variety of replaceable units can be configure to be attached to said central unit.

Abstract: Embodiments of the present invention recite a method and system for displaying data on a portable electronic device. In one embodiment, a first portion of accessed data is displayed on a portable electronic device. A motion detector responsive to motion in at least a single direction then detects a movement of the portable electronic device from a first position to a second position. In response to the motion detector detecting the movement, a second portion of the accessed data is automatically displayed by the portable electronic device.

Abstract: An amplification apparatus is disclosed. The amplification apparatus includes a plurality of emitters formed on a first substrate, an anode formed adjacent to a second substrate, so that current can be conducted between the emitters of the first substrate and the anode of the second substrate. A lens is formed adjacent to the emitters for controlling a magnitude of the current, thereby providing amplification of a signal applied to the lens. An inter-substrate material connects the first substrate and the second substrate, forming a vacuum that includes the emitters, the anode and the lens. Either the first substrate or the second substrate includes solid state memory. An alternate embodiment includes a storage medium for receiving an electron beam from the electron emitter, the storage medium having a storage area, the storage area being in one of a plurality of states as determined by an electron beam generated by the electron emitter.

Abstract: A method for improving display functionality comprising: (A) detecting movement of a portable display over a physical area by using a motion detector; (B) obtaining a set of data related to the physical area by using an image device; (C) processing the set of data related to the physical area; and (D) displaying the set of data related to the physical area on the portable display, wherein a mode of display is based on a mode of movement of the portable display.

Abstract: Embodiments of the present invention recite a method and system for extending the lifespan of a touch screen assembly. In one embodiment, a signal is received indicating an input pressure is being applied to a touch screen assembly. It is then determined that the input pressure comprises a valid input event and the coordinates of the valid input event are received from the touch screen assembly.

Abstract: A system comprising an elongated member, sized and shaped to be inserted within a subject's trachea, the elongated member comprising proximal and distal ends; a seal, extending around the elongated member at or near the distal end of the elongated member; at least one wicking fluid pickup port, positioned near the distal end of the elongated member, the at least one wicking fluid pickup port located more proximal than at least a portion of the seal; and at least one lumen, coupled in fluid communication with the at least one wicking fluid pickup port and extending toward the proximal end of the elongated member, the seal comprising an inflatable cuff having a proximal surface, wherein the at least one wicking fluid pickup port is disposed near an inner tracheal wall when the distal end of the elongated member is positioned within a trachea of a person and the inflatable cuff is inflated.

Abstract: A system for scheduling a conference between callers includes a database that stores scheduling information indicating at least a start time, a duration, and a maximum number of callers for one or more scheduled conferences, the scheduling information reflecting available conferencing resources. A server complex coupled to the database communicates, to a requesting Internet Protocol (IP) user, at least one page including one or more scheduling input fields. The server complex receives scheduling input from the requesting IP user for a requested conference according to the scheduling input fields. The server complex accesses the database to determine, according to the scheduling input, whether sufficient resources are available for the requested conference. If so, the server complex allocates at least some available resources to the requested conference and generates confirmations of the requested conference for communication to the callers.

Abstract: An inkjet printer includes a printhead having a plurality of ink orifices formed therein. During printing, ink drops are ejected through the ink orifices into a print zone between the printhead and a print medium. An air current disruption system directs an air stream through the print zone as the ink drops are ejected so as to disrupt air currents acting on the ink drops during printing and prevent print defects caused by the air currents. The air stream, however, does not disrupt an intended trajectory of the ink drops during printing.

Abstract: A system for scheduling a conference between callers includes a database that stores scheduling information indicating at least a start time, a duration, and a maximum number of callers for one or more scheduled conferences, the scheduling information reflecting available conferencing resources. A server complex coupled to the database communicates, to a requesting Internet Protocol (IP) user, at least one page including one or more scheduling input fields. The server complex receives scheduling input from the requesting IP user for a requested conference according to the scheduling input fields. The server complex accesses the database to determine, according to the scheduling input, whether sufficient resources are available for the requested conference. If so, the server complex allocates at least some available resources to the requested conference and generates confirmations of the requested conference for communication to the callers.

Abstract: Described herein is a monolithic printhead formed using integrated circuit techniques. Thin film layers, including ink ejection elements, are formed on a top surface of a silicon substrate. The various layers are etched to provide conductive leads to the ink ejection elements. At least one ink feed hole is formed through the thin film layers for each ink ejection chamber. A trench is etched in the bottom surface of the substrate so that ink can flow into the trench and into each ink ejection chamber through the ink feed holes formed in the thin film layers. An orifice layer is formed on the top surface of the thin film layers to define the nozzles and ink ejection chambers. A phosphosilicate glass (PSG) layer, providing an insulation layer beneath the resistive layers, is etched back from the ink feed holes and is protected by a passivation layer to prevent the ink from interacting with the PSG layer. Other layers may also be protected from the ink by being etched back.

Abstract: Described herein is a monolithic printhead formed using integrated circuit techniques. Thin film layers, including ink ejection elements, are formed on a top surface of a silicon substrate. The various layers are etched to provide conductive leads to the ink ejection elements. At least one ink feed hole is formed through the thin film layers for each ink ejection chamber. A trench is etched in the bottom surface of the substrate so that ink can flow into the trench and into each ink ejection chamber through the ink feed holes formed in the thin film layers. An orifice layer is formed on the top surface of the thin film layers to define the nozzles and ink ejection chambers. A phosphosilicate glass (PSG) layer, providing an insulation layer beneath the resistive layers, is etched back from the ink feed holes and is protected by a passivation layer to prevent the ink from interacting with the PSG layer. Other layers may also be protected from the ink by being etched back.

Abstract: Described herein is a monolithic printhead formed using integrated circuit techniques. Thin film layers, including ink ejection elements, are formed on a top surface of a silicon substrate. The various layers are etched to provide conductive leads to the ink ejection elements. At least one ink feed hole is formed through the thin film layers for each ink ejection chamber. A trench is etched in the bottom surface of the substrate so that ink can flow into the trench and into each ink ejection chamber through the ink feed holes formed in the thin film layers. An orifice layer is formed on the top surface of the thin film layers to define the nozzles and ink ejection chambers. A phosphosilicate glass (PSG) layer, providing an insulation layer beneath the resistive layers, is etched back from the ink feed holes and is protected by a passivation layer to prevent the ink from interacting with the PSG layer. Other layers may also be protected from the ink by being etched back.