Patents by Inventor Paul Jansen

Paul Jansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230417755
    Abstract: A method for increasing the light emission produced by the chemiluminescent reaction of 8-amino-5-chloro-7-phenylpyrido[3,4-d]pyridazine-1,4(2H,3H)-dione, a peroxidase enzyme or a conjugate thereof, an enhancer, a co-enhancer and a peroxide oxidizer, wherein the enhancer is an anionic N-alkylphenothiazine and the co-enhancer is selected from a 4-dialkylaminopyridine or an N-azole, and wherein the method comprises the following steps: i. realizing a chemiluminescent substrate by means of mixing together 8-amino-5-chloro-7-phenylpyrido[3,4-d]pyridazine-1,4(2H,3H)-dione, the enhancer, the co-enhancer and the peroxide oxidizer, and ii. adding the peroxidase enzyme or a conjugate thereof to the chemiluminescent substrate.
    Type: Application
    Filed: September 8, 2023
    Publication date: December 28, 2023
    Inventors: Leopoldo DELLA CIANA, Lorenzo BIAGINI, Thomas Paul JANSEN, Rossana PERCIACCANTE, Manuela VARGIOLU, Marina Eleonora VETTRAINO
  • Patent number: 11761964
    Abstract: A method for increasing the light emission produced by the chemiluminescent reaction of 8-amino-5-chloro-7-phenylpyrido[3,4-d]pyridazine-1,4(2H,3H)-dione, a peroxidase enzyme or a conjugate thereof, an enhancer, a co-enhancer and a peroxide oxidizer, wherein the enhancer is an anionic N-alkylphenothiazine and the co-enhancer is selected from a 4-dialkylaminopyridine or an N-azole, and wherein the method comprises the following steps: i. realizing a chemiluminescent substrate by means of mixing together 8-amino-5-chloro-7-phenylpyrido[3,4-d]pyridazine-1,4(2H,3H)-dione, the enhancer, the co-enhancer and the peroxide oxidizer, and ii. adding the peroxidase enzyme or a conjugate thereof to the chemiluminescent substrate.
    Type: Grant
    Filed: January 22, 2020
    Date of Patent: September 19, 2023
    Assignee: CYANAGEN S.r.l.
    Inventors: Leopoldo Della Ciana, Lorenzo Biagini, Thomas Paul Jansen, Rossana Perciaccante, Manuela Vargiolu, Marina Eleonora Vettraino
  • Patent number: 11573183
    Abstract: A kit for performing an assay for determining an analyte in a sample with an extended shelf-life, wherein the kit comprises a chemiluminescent cyclic dihydrazide, an enhancer, a co-enhancer, and a peroxide oxidizer. The kit is useful in blot assays and immunoassays for the detection of proteins and nucleic acid molecules.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: February 7, 2023
    Assignee: CYANAGEN S.r.l.
    Inventors: Leopoldo Della Ciana, Lorenzo Biagini, Thomas Paul Jansen, Rossana Perciaccante, Manuela Vargiolu, Marina Eleonora Vettraino
  • Patent number: 11140881
    Abstract: There is provided an illumination system (100) for cultivation of aquatic animals. The illumination system (100) comprises at least one light source (110) emitting light, at least one light driver (120) arranged to drive the at least one light source (110), at least one light sensor (130) providing illuminance data for at least one point of interest (50) in said illumination system (100), and a controller (140). The controller (140) is adapted to provide control signals to the at least one light driver (120) driving the at least one light source (110) to emit light of a desired illuminance at the at least one point of interest (50). An ambient light sensor may be applied to determine control signals also in accordance with ambient light data.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: October 12, 2021
    Assignee: SIGNIFY HOLDING B.V.
    Inventors: Erik Paul Boonekamp, Christina Tanase, Martijn Evert Paul Jansen, Willem Franke Pasveer, Hilbrand Vanden Wyngaert, René Van Honschooten, Peter Johannes Martinus Bukkems
  • Publication number: 20210231572
    Abstract: A kit for performing an assay for determining an analyte in a sample with an extended shelf-life, wherein the kit comprises a chemiluminescent cyclic dihydrazide, an enhancer, a co-enhancer, and a peroxide oxidizer. The kit is useful in blot assays and immunoassays for the detection of proteins and nucleic acid molecules.
    Type: Application
    Filed: January 22, 2021
    Publication date: July 29, 2021
    Inventors: Leopoldo DELLA CIANA, Lorenzo BIAGINI, Thomas Paul JANSEN, Rossana PERCIACCANTE, Manuela VARGIOLU, Marina Eleonora VETTRAINO
  • Publication number: 20210153820
    Abstract: A modular patient monitor has a docking station configured to accept a handheld monitor. The docking station has standalone patient monitoring functionality with respect to a first set of parameters. At least some of the first parameter set are displayed simultaneously on a full-sized screen integrated with the docking station. The handheld monitor also has standalone patient monitoring functionality with respect to a second set of parameters. At least some of the second set of parameters are displayed simultaneously on a handheld-sized screen integrated with the handheld monitor. The docking station has a port configured to accept the handheld monitor. While the handheld monitor is docket in the port, the docking station functionally combines the first set of parameters and the second set of parameters, and at least some of the combined first and second sets of parameters are displayed simultaneously on the full-sized screen.
    Type: Application
    Filed: January 5, 2021
    Publication date: May 27, 2021
    Inventors: Ammar Al-Ali, Paul Jansen, Massi Joe E. Kiani, Anand Sampath
  • Patent number: 10912524
    Abstract: A modular patient monitor has a docking station configured to accept a handheld monitor. The docking station has standalone patient monitoring functionality with respect to a first set of parameters. At least some of the first parameter set are displayed simultaneously on a full-sized screen integrated with the docking station. The handheld monitor also has standalone patient monitoring functionality with respect to a second set of parameters. At least some of the second set of parameters are displayed simultaneously on a handheld-sized screen integrated with the handheld monitor. The docking station has a port configured to accept the handheld monitor. While the handheld monitor is docket in the port, the docking station functionally combines the first set of parameters and the second set of parameters, and at least some of the combined first and second sets of parameters are displayed simultaneously on the full-sized screen.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: February 9, 2021
    Assignee: Masimo Corporation
    Inventors: Ammar Al-Ali, Paul Jansen, Massi Joe E. Kiani, Anand Sampath
  • Patent number: 10863728
    Abstract: An illumination system for cultivation of aquatic animals is disclosed for cultivation of aquatic animals in a volume of water, the cultivation using a feeding system defining a feeding axis in the volume of water. The system comprises at least a first illumination surface positioned in the volume of water and arranged for illuminating the feeding axis. The system also comprises a second illumination surface positioned in the volume of water and arranged for illuminating the feeding axis. The first illumination surface and second illumination surface are different surfaces arranged to illuminate the feeding axis from substantially different directions.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: December 15, 2020
    Assignee: SIGNIFY HOLDING B.V.
    Inventors: Joris Jan Vrehen, Vincent Stefan David Gielen, Georges Marie Calon, Willem Franke Pasveer, Martijn Evert Paul Jansen, Erik Paul Boonekamp, Hilbrand Vanden Wyngaert
  • Patent number: 10793501
    Abstract: The invention pertains to a method for providing a succinic acid solution, comprising the steps of —providing a first magnesium succinate containing medium with a magnesium succinate concentration of 18-23 wt. % to a first acidification reactor where it is contacted with hydrogen chloride to form a solution of succinic acid, magnesium chloride and hydrogen chloride, —providing a second magnesium succinate containing medium with a magnesium succinate concentration of 25-50 wt. %, and contacting it in a second acidification reactor with the solution of succinic acid, magnesium chloride and hydrogen chloride withdrawn from the first acidification reactor, to form an aqueous mixture comprising magnesium chloride and succinic acid with a succinic acid concentration of at least 18 wt. %. The method according to the invention makes it possible to obtain a solution comprising succinic acid and magnesium 20 chloride with an increased succinic acid concentration.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: October 6, 2020
    Assignee: PURAC BIOCHEM B.V.
    Inventors: Peter Paul Jansen, Jan Van Breugel, Gerard Hendrik Van Bochove, Jose Maria Vidal Lancis, Tanja Dekic Zivkovic
  • Publication number: 20200232991
    Abstract: A method for increasing the light emission produced by the chemiluminescent reaction of 8-amino-5-chloro-7-phenylpyrido[3,4-d]pyridazine-1,4(2H,3H)-dione, a peroxidase enzyme or a conjugate thereof, an enhancer, a co-enhancer and a peroxide oxidizer, wherein the enhancer is an anionic N-alkylphenothiazine and the co-enhancer is selected from a 4-dialkylaminopyridine or an N-azole, and wherein the method comprises the following steps: i. realizing a chemiluminescent substrate by means of mixing together 8-amino-5-chloro-7-phenylpyrido[3,4-d]pyridazine-1,4(2H,3H)-dione, the enhancer, the co-enhancer and the peroxide oxidizer, and ii. adding the peroxidase enzyme or a conjugate thereof to the chemiluminescent substrate.
    Type: Application
    Filed: January 22, 2020
    Publication date: July 23, 2020
    Inventors: Leopoldo DELLA CIANA, Lorenzo BIAGINI, Thomas Paul JANSEN, Rossana PERCIACCANTE, Manuela VARGIOLU, Marina Eleonora VETTRAINO
  • Patent number: 10508069
    Abstract: The invention provides a method for preparing a carboxylic acid, which method includes the steps of providing magnesium carboxylate, wherein the carboxylic acid corresponding with the carboxylate has a solubility in water at 20° C. of 80 g/100 g water or less; acidifying the magnesium carboxylate with HCl, thereby obtaining a solution comprising carboxylic acid and magnesium chloride (MgCl2); optionally a concentration step, wherein the solution comprising carboxylic acid and MgCl2 is concentrated; precipitating the carboxylic acid from the solution comprising the carboxylic acid and MgCl2, thereby obtaining a carboxylic acid precipitate and a MgCl2 solution.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: December 17, 2019
    Assignee: PURAC BIOCHEM B.V.
    Inventors: André Banier De Haan, Jan Van Breugel, Paulus Loduvicus Johannes Van Der Weide, Peter Paul Jansen, José Maria Vidal Lancis, Agustin Cerdà Baró
  • Patent number: 10160861
    Abstract: The present invention describes novel 7-alkylamino-3-(thienyl) coumarin fluorescent dyes of formula (I) These dyes are water soluble, can be excited by the 405 nm excitation source and exhibit a large Stokes shift (?80 nm). Furthermore, the dyes possess a reactive group for the labeling of biomolecules or other analytes.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: December 25, 2018
    Assignee: CYANAGEN S.r.l.
    Inventors: Thomas Paul Jansen, Giacomo Rodeghiero, Dario Foglietta, Rossana Perciaccante, Leopoldo Della Ciana
  • Publication number: 20180319731
    Abstract: The invention provides a method for preparing a carboxylic acid, which method includes the steps of providing magnesium carboxylate, wherein the carboxylic acid corresponding with the carboxylate has a solubility in water at 20° C. of 80 g/100 g water or less; acidifying the magnesium carboxylate with HCl, thereby obtaining a solution comprising carboxylic acid and magnesium chloride (MgCl2); optionally a concentration step, wherein the solution comprising carboxylic acid and MgCl2 is concentrated; precipitating the carboxylic acid from the solution comprising the carboxylic acid and MgCl2, thereby obtaining a carboxylic acid precipitate and a MgCl2 solution.
    Type: Application
    Filed: July 9, 2018
    Publication date: November 8, 2018
    Inventors: André Banier DE HAAN, Jan VAN BREUGEL, Paulus Loduvicus Johannes VAN DER WEIDE, Peter Paul JANSEN, José Maria VIDAL LANCIS, Agustin CERDÀ BARÓ
  • Patent number: 10093608
    Abstract: The invention pertains to a method for preparing succinic acid which comprises providing an aqueous magnesium succinate solution to an acidification step, wherein the magnesium succinate solution is acidified by the addition of hydrogen chloride, thereby obtaining an aqueous solution comprising succinic acid and magnesium chloride and subjecting the aqueous solution comprising succinic acid and magnesium chloride derived from the acidification step to a treatment step with active carbon followed by precipitating succinic acid from an aqueous mixture comprising succinic acid and magnesium chloride resulting from the active carbon treatment step in a precipitation step to form solid succinic acid. It has been found that the method according to the invention leads to succinic acid crystals with better properties than a comparable method wherein no active carbon treatment is used.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: October 9, 2018
    Assignee: PURAC BIOCHEM B.V.
    Inventors: Jan Van Breugel, Peter Paul Jansen, Jose Maria Vidal Lancis, Tanja Dekic Zivkovic, Adriaan Dirk Kon
  • Patent number: 10071948
    Abstract: The invention provides a method for preparing a carboxylic acid, which method includes the steps of providing magnesium carboxylate, wherein the carboxylic acid corresponding with the carboxylate has a solubility in water at 20° C. of 80 g/100 g water or less; acidifying the magnesium carboxylate with HCl, thereby obtaining a solution comprising carboxylic acid and magnesium chloride (MgCl2); optionally a concentration step, wherein the solution comprising carboxylic acid and MgCl2 is concentrated; precipitating the carboxylic acid from the solution comprising the carboxylic acid and MgCl2, thereby obtaining a carboxylic acid precipitate and a MgCl2 solution.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: September 11, 2018
    Assignee: PURAC BIOCHEM B.V.
    Inventors: André Banier De Haan, Jan Van Breugel, Paulus Loduvicus Johannes Van Der Weide, Peter Paul Jansen, José Maria Vidal Lancis, Agustín Cerdà Baró
  • Publication number: 20180208534
    Abstract: The invention pertains to a method for providing a succinic acid solution, comprising the steps of—providing a first magnesium succinate containing medium with a magnesium succinate concentration of 18-23 wt. % to a first acidification reactor where it is contacted with hydrogen chloride to form a solution of succinic acid, magnesium chloride and hydrogen chloride,—providing a second magnesium succinate containing medium with a magnesium 3 succinate concentration of 25-50 wt. %, and contacting it in a second acidification reactor with the solution of succinic acid, magnesium chloride and hydrogen chloride withdrawn from the first acidification reactor, to form an aqueous mixture comprising magnesium chloride and succinic acid with a succinic acid concentration of at least 18 wt. %. the method according to the invention makes it possible to obtain a solution comprising succinic acid and magnesium 20 chloride with an increased succinic acid concentration.
    Type: Application
    Filed: July 29, 2016
    Publication date: July 26, 2018
    Inventors: Peter Paul JANSEN, Jan VAN BREUGEL, Gerard Hendrik VAN BOCHOVE, Jose Maria VIDAL LANCIS, Tanja DEKIC ZIVKOVIC
  • Publication number: 20180194706
    Abstract: The invention pertains to a method for preparing succinic acid comprising the steps of —providing an aqueous magnesium succinate solution to an acidification step, wherein the magnesium succinate solution is acidified by the addition of hydrogen chloride, thereby obtaining an aqueous solution comprising succinic acid and magnesium chloride; —subjecting an aqueous solution comprising succinic acid and magnesium chloride derived from the acidification step to a treatment step with active carbon, —precipitating succinic acid from an aqueous mixture comprising succinic acid and magnesium chloride resulting from the active carbon treatment step in a precipitation step to form solid succinic acid and a magnesium chloride solution, —separating the solid succinic acid from the magnesium chloride solution —subjecting the magnesium chloride solution to a thermal decomposition at a temperature of at least 300° C.
    Type: Application
    Filed: July 14, 2016
    Publication date: July 12, 2018
    Inventors: Jan VAN BREUGEL, Peter Paul JANSEN, Jose Maria VIDAL LANCIS, Tanja DEKIC ZIVKOVIC, Adriaan Dirk KON
  • Patent number: 10017446
    Abstract: The invention provides a method for preparing a carboxylic acid, which method includes the steps of providing magnesium carboxylate, wherein the carboxylic acid corresponding with the carboxylate has a solubility in water at 20° C. of 80 g/100 g water or less; acidifying the magnesium carboxylate with HCl, thereby obtaining a solution comprising carboxylic acid and magnesium chloride (MgCl2); optionally a concentration step, wherein the solution comprising carboxylic acid and MgCl2 is concentrated; precipitating the carboxylic acid from the solution comprising the carboxylic acid and MgCl2, thereby obtaining a carboxylic acid precipitate and a MgCl2 solution.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: July 10, 2018
    Assignee: PURAC BIOCHEM B.V.
    Inventors: André Banier De Haan, Jan Van Breugel, Paulus Loduvicus Johannes Van Der Weide, Peter Paul Jansen, José Maria Vidal Lancis, Agustín Cerdà Baró
  • Patent number: 9923325
    Abstract: The present invention relates to an end cap (104) for a tubular light source the tubular light source configured to be arranged in a lighting fixture comprising a socket, wherein the end cap (104) comprises a housing portion having a connection end, two connector pins (116) at least partly arranged on an outside of the housing portion at the connection end, wherein the connector pins (116) are configured to fit in the sockets of the lighting fixture, a first spring loaded switching element (110) configured to be alternately positioned in an actuated state and a non-actuated state, wherein the first spring loaded switching element (110) protrudes at the connection end of the housing portion in the vicinity of the connector pins (116) when positioned in its non-actuated state, and a second spring loaded switching element (112) configured to be positioned in an actuated state and a non-actuated state, wherein the switching elements (110, 112) are configured to be individually positioned in their respective actua
    Type: Grant
    Filed: January 7, 2014
    Date of Patent: March 20, 2018
    Assignee: PHILIPS LIGHTING HOLDING B.V.
    Inventors: Martijn Evert Paul Jansen, Hongwu Wang, Mark Johannes Antonius Verhoeven, Liang Zhou, Vincent Stefan David Gielen, Peter Johannes Martinus Bukkems, Georges Marie Calon, Reinier Imre Anton Den Boer, Eugen Jacob De Mol
  • Patent number: 9890942
    Abstract: A lamp comprising a driver assembly, the driver assembly including a driver board with driver electronics, at least one point light source and a heat sink, the heat sink including a top side and a bottom side, a central space extending from the bottom side to the top side and adapted for receiving the driver board of the driver assembly, a zone provided at the top side and adapted for receiving the at least one point light source, wherein a plurality of fins adapted for dissipating heat are extending on opposite sides of the central space, and an extension of the central space in at least one radial direction of the heat sink is larger than an extension of the zone in the radial direction of the heat sink such that the central space is provided with at least one section arranged offset from and radially adjacent to the zone.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: February 13, 2018
    Assignee: PHILIPS LIGHTING HOLDING B.V.
    Inventors: Lihua Lin, Aldo Tralli, Theodoor Cornelis Treurniet, Aldegonda Lucia Weijers, Martijn Evert Paul Jansen, Sait Izmit