Abstract: A method for preparing a carboxylic acid, includes the steps of: providing magnesium carboxylate, wherein the carboxylic acid corresponding with the carboxylate is selected from the group made of 2,5-furandicarboxylic acid, fumaric acid, adipic acid, itaconic acid, citric acid, glutaric acid, maleic acid, malonic acid, oxalic acid and fatty acids having more than 10 carbon atoms; acidifying the magnesium carboxylate with hydrogen chloride (HCl), thereby obtaining a solution including carboxylic acid and magnesium chloride (MgCl2); optionally a concentration step, wherein the solution including carboxylic acid and MgCl2 is concentrated; and precipitating the carboxylic acid from the solution including the carboxylic acid and MgCl2, thereby obtaining a carboxylic acid precipitate and a MgCl2 solution.

Abstract: A modular patient monitor has a docking station configured to accept a handheld monitor. The docking station has standalone patient monitoring functionality with respect to a first set of parameters. At least some of the first parameter set are displayed simultaneously on a full-sized screen integrated with the docking station. The handheld monitor also has standalone patient monitoring functionality with respect to a second set of parameters. At least some of the second set of parameters are displayed simultaneously on a handheld-sized screen integrated with the handheld monitor. The docking station has a port configured to accept the handheld monitor. While the handheld monitor is docket in the port, the docking station functionally combines the first set of parameters and the second set of parameters, and at least some of the combined first and second sets of parameters are displayed simultaneously on the full-sized screen.

Abstract: The invention provides a method for preparing a succinic acid, which method includes the steps of: providing magnesium succinate; acidifying the magnesium succinate with hydrochloric acid (HCl), thereby obtaining a solution including succinic acid and magnesium chloride (MgCl2); optionally a concentration step, wherein the solution including succinic acid and MgCl2 is concentrated; precipitating succinic acid from the solution including succinic acid and MgCl2, thereby obtaining a succinic acid precipitate and a MgCl2 solution. The addition of HCl to a magnesium salt of succinic acid and subsequent precipitation of succinic acid from the solution leads to a very efficient separation of succinic acid from a magnesium succinate solution.

Abstract: A control solution packet for calibrating a bodily fluid sampling device includes a container, a control solution pressurized within the container, and a membrane for covering and sealing the container. The control solution can be pressurized before or during calibration so as to ensure the appropriate amount of control solution is delivered to the bodily fluid sampling device. The control solution is manufactured to have a viscosity that controls delivery of the control solution to the device. The membrane is permeable by a piercing device of the bodily fluid sampling device and seals around the piercing device during calibration. In another aspect, the container is in the form of a capsule or dosing attachment that contains the control solution along with a sponge-like material.

Abstract: The invention concerns an analytical instrument for assaying body fluids, the instrument having the following features: a) a housing provided with a receiving element for engaging a body part, b) an abutment for the body part which can be moved between a release position and an operating position relative to the receiving element, c) a lancing unit having a lancing element that can pierce the body part resting against the abutment in a linear lancing stroke, d) a test tape unit having a test tape for receiving body fluid issuing from the body part, and e) a detection unit for examining the body fluid applied to a section of the test tape.

Abstract: The invention relates to an analysis system for analyzing a sample on a test element. The system has an analysis unit for generating a signal as a function of an analyte contained in a sample, and a detection unit for detecting the signal. The analysis system further includes a test element holder into which the test element can be reversibly introduced and in which it can be positioned relative to the analysis unit and the detection unit. The test element contains at least one guide element, which is suitable for laterally guiding the test element, so that the test element in the test element holder is held and guided only on an outer region of the test element, and an inner region of the test element introduced into the test element holder remains free. The test element contains a sample application site in the inner region.

Abstract: A piston compressor with at least one compression cylinder having a piston, and with one suction port and one pressure port is described. The suction port and the pressure port are arranged at one end face of the compression cylinder.

Abstract: The invention relates to an analysis system for analyzing a sample on a test element. The system has an analysis unit for generating a signal as a function of an analyte contained in a sample, and a detection unit for detecting the signal. The analysis system further includes a test element holder into which the test element can be reversibly introduced and in which it can be positioned relative to the analysis unit and the detection unit. The test element contains at least one guide element, which is suitable for laterally guiding the test element, so that the test element in the test element holder is held and guided only on an outer region of the test element, and an inner region of the test element introduced into the test element holder remains free. The test element contains a sample application site in the inner region.

Abstract: A fermentation process includes contacting a carbohydrate source with a microorganism in an aqueous fermentation broth to form a fermentation product which is a salt or a product with a boiling point above the boiling point of water. The fermentation process is carried out at a pressure which is below atmospheric pressure and at least at the value where the reaction medium is at its boiling point at the fermentation temperature. Water is evaporated and removed from the reactor during the fermentation in an amount which is at least 20% of the volume of liquid present in the reactor at the start of the fermentation. A fermentation process at reduced pressure while removing a substantial amount of water removes a surplus of water in the system, ensures removal of reaction heat, and may lead to improved fermentation quality.

Abstract: A non-invasive electronic patient monitor tracks one or more physiological parameters of a patient, such as intravascular volume index (IVI), extravascular volume index (EVI), total hemoglobin (SpHb), impedance, and/or weight. The patient monitor determines if one or more of the physiological parameters are within a predetermined range. The patient monitor activates an alarm if one or more of the physiological parameters are outside the predetermined range and indicates a patient can be experiencing edema and/or heart failure, or sepsis.

Abstract: A control solution packet for calibrating a bodily fluid sampling device includes a container, a control solution pressurized within the container, and a membrane for covering and sealing the container. The control solution can be pressurized before or during calibration so as to ensure the appropriate amount of control solution is delivered to the bodily fluid sampling device. The control solution is manufactured to have a viscosity that controls delivery of the control solution to the device. The membrane is permeable by a piercing device of the bodily fluid sampling device and seals around the piercing device during calibration. In another aspect, the container is in the form of a capsule or dosing attachment that contains the control solution along with a sponge-like material.

Abstract: A control solution packet for calibrating a bodily fluid sampling device includes a container, a control solution pressurized within the container, and a membrane for covering and sealing the container. The control solution can be pressurized before or during calibration so as to ensure the appropriate amount of control solution is delivered to the bodily fluid sampling device. The control solution is manufactured to have a viscosity that controls delivery of the control solution to the device. The membrane is permeable by a piercing device of the bodily fluid sampling device and seals around the piercing device during calibration. In another aspect, the container is in the form of a capsule or dosing attachment that contains the control solution along with a sponge-like material.

Abstract: A continuous process for the ring-opening polymerisation of cyclic ester monomers to form aliphatic polyesters at a temperature between 100-240° C. which includes a) continuously providing cyclic ester monomer and polymerisation catalyst to a continuous mixing reactor, the reactor being operated at conditions effective for polymerisation to form a pre-polymerised reaction mixture, b) continuously removing pre-polymerised reaction mixture from the continuous mixing reactor and continuously providing pre-polymerised reaction mixture to a plug flow reactor, the plug flow reactor being operated under polymerisation conditions, wherein the reaction mixture is polymerised to a degree of polymerisation of at least 90%, to form polymer, and c) continuously removing polymer from the plug flow reactor.

Abstract: The invention relates to a hand-held analytical device for analyzing a sample, in particular a biological fluid, for a medically significant component, comprising a housing comprising a loading opening for receiving a replaceable cartridge having multiple chambers that may contain analytical consumables, in particular test strips, and each chamber comprising an opening on at least one face of the cartridge and each opening may be sealed by a sealing foil, a removal facility for removing one of the analytical consumables from the cartridge. The removal facility can be used to remove one of the consumables from one of the chambers of the cartridge, in the process of which the opening sealed by the sealing foil is opened. A drive allows the cartridge to be moved in order to position one chamber in a removal position in which a consumable can be removed from the chamber by the removal facility.

Abstract: The invention refers to an injection device for the injection of a medical agent, in particular insulin, comprising: a housing, a reception compartment for a vial containing the agent to be injected, advancement mechanics for moving an injection needle that is inserted in the device in a direction of puncturing, and a pressing facility for pressing agent from a vial that is inserted in the reception compartment for the purpose of an injection process. The advancement mechanics, effects, in a first device function for an injection process, a first motion profile of an inserted injection needle, in which a resting phase follows after an advancement motion, during which resting phase the inserted injection needle for an injection process is at rest with respect to the device housing, and effects, in a second device function for obtaining a body fluid sample for diagnostic purposes, a second motion profile of an inserted injection needle, in which a returning motion follows immediately after a puncturing motion.

Abstract: A patient monitor system is configured to measure and display a hemoglobin concentration measurement to assist caregivers in providing care or treatment and/or to automatically control a fluid, blood, medicine, or dialysis administration system. The patient monitor can analyze the displayed hemoglobin concentration measurement and provide alarms and feedback to assist caregivers. Additional measurement can be combined with the hemoglobin concentration measurement to provide combined displays helpful to caregivers, such as, for example, a plethysmograph variability index v. SpHb display.

Abstract: A piston compressor with at least one compression cylinder having a piston, and with one suction port and one pressure port is described. The suction port and the pressure port are arranged at one end face of the compression cylinder.

Abstract: A method and system for proving a drug delivery device. The device comprises a drug delivery device housing and a medicament contained in the drug delivery device housing. A dose dial sleeve is positioned in the housing and is rotatable to set a non-inverted dose of the medicament contained in the medical delivery device. The non-inverted dose may be increased by turning the dose dial sleeve in a direction towards a user of the drug delivery device. The dose medicament may be decreased by rotating the dose dial sleeve in a direction away from the user.

Abstract: The invention relates to a method for the preparation of a stable alkali metal lactate in powder form, the product of said preparation, functional pre-mixes for foodstuff comprising said stable alkali metal lactate powder, and foodstuffs comprising said stable alkali metal lactate powder. In the method According to the invention, a concentrate that contains alkali metal lactate is processed, with cooling, in a mixer/extruder to form a powder of the alkali metal lactate. According to the invention the alkali metal lactates in powder form are stable for at least 48 hours.

Abstract: A medical device is provided, comprising a data management unit for providing patient data regarding a patient's health and/or treatment status, a display for displaying the patient data provided by the data management unit, and an actuator configured to cause one or both of activation and deactivation of the device. The patient data is displayed on the display in response to the initiation of activation and/or deactivation of the device.