Abstract: The invention relates to an X-ray image analysis system (4) comprising an X-ray image input interface (8) and a computing unit (9). The X-ray image input interface (8) is configured to receive X-ray images (14) taken by an X-ray imaging system (1) comprising an X-ray source (2) and an X-ray detector (3). The computing unit (9) is connected to the X-ray image input interface (8) and configured to obtain at least one X-ray image (14) from the X-ray image input interface (8) and perform a scapula position detection, including inputting the X-ray image (14) into a trained machine-learning system, running the trained machine-learning system, and obtaining a scapula position. The computing unit (9) is further configured to transmit scapula position information from a scapula position information output interface (10) to a display (5).

Abstract: A server rack is cabled to obviate the need for top-of-rack switches. Switches and severs are connected through de-mateable connection interfaces at distribution modules disposed along the raceway above the server cabinets. The distribution modules may have externally accessible ports, internally accessible ports, and/or payout spools for the switch cables and/or the server cables.

Abstract: The composition inhibits severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) via competitive binding to SARS-COV-2 spike protein. The composition includes a plurality of sulfated glycosaminoglycans which bind to SARS-COV-2 spike protein, preventing binding to and uptake by host cells. The sulfated glycosaminoglycans, including N-, 2-O, 3-O, or 6-O sulfate groups, or combinations thereof, include heparins and fucoidans, such as those isolated from brown seaweed. The compositions show antiviral activity, with EC50 as low as 0.08 ?M, and low cytotoxicity, making it promising for clinical use. While established SARS-COV-2 treatments such as remdesivir need to be administered intravenously, the compositions discussed herein are advantageously capable to being delivered as a nasal spray, metered dose inhaler, oral delivery, etc.

Abstract: A tissue repair assembly is disclosed, including a soft anchor body and at least a first suture operably coupled to the anchor body. Tensioning on first and/or second ends of first suture may deploy the anchor body to a second configuration, in which the anchor body is axially compressed and radially extended. The tissue repair assembly may also include a means to cinch around a portion of a first and/or second suture and knotlessly lock the tissue repair assembly. Some embodiments may include a pre-formed knot. In some embodiments, the preformed knot may be a nail knot, provided wrapped around an insertion instrument and configured to receive and cinch around a suture extending therethrough.

Abstract: The composition inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via competitive binding to SARS-CoV-2 spike protein. The composition includes a plurality of sulfated glycosaminoglycans which bind to SARS-CoV-2 spike protein, preventing binding to and uptake by host cells. The sulfated glycosaminoglycans, including N-, 2-O, 3-O, or 6-O sulfate groups, or combinations thereof, include heparins and fucoidans, such as those isolated from brown seaweed. The compositions show antiviral activity, with EC50 as low as 0.08 ?M, and low cytotoxicity, making it promising for clinical use. While established SARS-CoV-2 treatments such as remdesivir need to be administered intravenously, the compositions discussed herein are advantageously capable to being delivered as a nasal spray, metered dose inhaler, oral delivery, etc.

Abstract: Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-glycoprotein conjugate.

Abstract: System and method are provided for automation of placing and transporting of parcels or packages in containers. Aspects of disclosure provide automation for filling and manipulation of containers, and closure of filled containers, in systems where materials, products, packages, and other items may require containerization. Other aspects of disclosure provide automation for transport of one or more empty and/or filled containers from/to various staging areas of such systems.

Abstract: A bracket includes a first wing, a second wing and a bridge that connects the first wing to the second wing. The first wing has a first inner surface and a first outer surface. The second wing has a second inner surface and a second outer surface. The bridge extends from the first inner surface to the second inner surface thereby coupling the first wing to the second wing such that the first inner surface is normal to a first direction, and the first inner surface is parallel to the second inner surface. The bridge includes a front edge and a rear edge. The front edge forms a recess that extends into the bridge towards the rear edge along a second direction that is perpendicular to the first direction, and the recess terminates within the bridge prior to reaching the rear edge.

Abstract: A two-phase immersion cooling system for an integrated circuit assembly may be formed utilizing boiling enhancement structures formed on or directly attached to heat dissipation devices within the integrated circuit assembly, formed on or directly attached to integrated circuit devices within the integrated circuit assembly, and/or conformally formed over support devices and at least a portion of an electronic board within the integrated circuit assembly. In still a further embodiment, the two-phase immersion cooling system may include a low boiling point liquid including at least two liquids that are substantially immiscible with one another.

Abstract: The present disclosure is related to methods of screening for the onset or predisposition to the onset of or monitoring an esophageal or gastric neoplasm in an individual, said method comprising assessing the methylation status of a selected DNA region in a biological sample from said individual wherein a higher level of methylation of at least one of the DNA regions relative to control levels is indicative of an esophageal or gastric neoplasm or a predisposition to the onset of a esophageal or gastric neoplasm.

Abstract: A system for improving graft harvesting including a blade guide (320) having a handle (370) and a guide portion with an elongate slot (330). The system may also include a first blade assembly (750) that slides along the elongate slot (330), the blade assembly (750) having a cutting blade (765) rotatably coupled to a handle (780). The cutting blade (765) may include a leading cutting edge and a trailing cutting edge. The blade assembly (350, 750) and blade guide (320) may cooperate to control a depth of blade penetration into a tissue, as the blade slides along the elongate slot (330). The blade guide (320) may include means to stabilize the guide with the tissue.

Abstract: System and method are provided where parcels or packages are associated or grouped, into logical group or logical containerization of parcels or packages, without need for physical container, such that parcels or packages can be tracked as a group, for example with a unique group ID. Logical group may be tracked within a specified logical zone, transported, sorted and/or otherwise processed as unique logical group in container, or without need to be contained in physical container. System and method for automated sortation can accumulate set number or set volume of packages, and then process the accumulated set number or volume of packages.

Abstract: Various aspects of this disclosure relate to a prosthetic cover comprising an array of sensors, which transmit signals to an array of electrodes in a liner that fits over a residual limb of an amputee. Different interactions with the prosthetic cover cause different activation of the electrodes to transmit electrical current through different areas of the residual limb and modulate neurons differently within the residual limb. Various aspects of this disclosure also relate to a prosthetic liner with a substrate that includes electrodes for transcutaneous electrical nerve stimulation and/or electronic muscle stimulation for a residual limb.

Abstract: The disclosed system and method is directed to enhancing feasibility of virtual card numbers (VCNs), as secure transaction instruments in online electronic transaction, by incorporating an offline attribute value, which may correspond to an element of the users physical card such as the CVV code, into the validation parameters specified for a VCN. This functionality may be implemented, on the validation end, by modifying a VCN data object to include a reference to the corresponding data element. The proposed system and method provides a more flexible and feasible implementation for conducting VCN transactions without compromising authentication security across network connections.

Abstract: Systems and methods to provide secure cryptographic authentication, verification, functionality access, and payments between contactless cards and communication devices are provided. An exemplary communication device includes a system on a chip and generates a communication field, displays a prompt to tap a contactless card on the communication device, reads the contactless card after entry into the communication field, performs an authentication of the contactless card, and after a successful authentication of the contactless card, and performs a payment transaction.

Abstract: In particular embodiments, a computing system may collect, for each ride of a plurality of rides, first ride data associated with a user riding a personal mobility vehicle during a certain time period. The system may calculate, for each ride, an approximate load on the personal mobility vehicle based on at least the first ride data. The system may calculate a user profile of the user based on the approximate loads. The system may collect, for a subsequent ride, second ride data associated with the user riding a current personal mobility vehicle after the certain time period. The system may calculate, for the subsequent ride, a second approximate load on the current personal mobility vehicle based on at least the second ride data. The system may compare the second approximate load to the user profile and classify the subsequent ride as individual or tandem based on the comparison.

Abstract: Systems and methods include a group fund processor having a communications interface that receives account data associated with a primary account from a device over a network, creates a group fund account, and associate one or more limits with the group fund account, an alert interface that transmits an electronic invitation including a description of a first amount to an invited user and receives a response from the invited user to the at least one invitation, wherein the response includes account data associated with a respective group member account of the invited user; and an account processor that links the group fund account to the primary account, and links respective group member account of the invited user to the group fund account so that the first amount is transferred from the respective group member account of the invited user to the group fund account.

Abstract: An inhaler with an inner housing with a pressurised reservoir of an inhalable composition. A breath operated valve is operable by a user inhaling on an inhaling end of the inhaler. A composition flow path extends from the breath operated valve to the inhaling end via which the composition is dispensed when the breath operated valve is opened. The breath operated valve is biased closed by a biasing member contacting the breath operated valve at one end. A bung in the inner housing is positioned in an opening in the inner housing to support the end of the biasing member opposite to the breath operated valve. A rigid outer housing surrounds the inner housing and supports the bung.