Patents by Inventor Paul Young

Paul Young has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STEAM GENERATOR FLOW BY-PASS SYSTEM
    Publication number: 20100124303
    Abstract: A nuclear reactor module includes a reactor vessel and a reactor housing mounted inside the reactor vessel, wherein the reactor housing comprises a shroud and a riser located above the shroud. The nuclear reactor module further includes a heat exchanger proximately located about the riser, and a reactor core located in the shroud. A steam generator by-pass system is configured to provide an auxiliary flow path of primary coolant to the reactor core to augment a primary flow path of the primary coolant out of the riser and into the shroud, wherein the auxiliary flow path of primary coolant exits the reactor housing without passing by the heat exchanger.
    Type: Application
    Filed: November 17, 2008
    Publication date: May 20, 2010
    Applicant: NuScale Power, Inc.
    Inventors: Eric Paul Young, John T. Groome, Jose N. Reyes, JR.
  • 33 Human Secreted Proteins
    Publication number: 20090305991
    Abstract: The present invention relates to 33 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: August 10, 2009
    Publication date: December 10, 2009
    Applicant: Human Genome Sciences, Inc.
    Inventors: Daniel R. Soppet, Paul A. Moore, Yanggu Shi, Steven M. Ruben, Craig A. Rosen, David W. LaFleur, Henrik Olsen, Reinhard Ebner, Kimberly Florence, Paul Young, George Komatsoulis, Jian Ni
  • METHOD FOR DETERMINING ADEQUACY OF SEISMIC DATA COVERAGE OF A SUBSURFACE AREA BEING SURVEYED AND ITS APPLICATION TO SELECTING SENSOR ARRAY GEOMETRY
    Publication number: 20090279388
    Abstract: A method for marine seismic surveying includes towing a seismic sensors in a plurality of streamers in the water, actuating a seismic energy source in the water at selected times and detecting seismic signals at the sensors resulting from the actuation of the source. A data trace is created for each of the detected signals. At least one Fresnel zone is determined for at least some of the seismic data traces. A contribution of each of the traces to each one of a plurality of bins defined in a predetermined pattern is computed, based on the Fresnel zone associated with each trace. Based on the computed contributions, a maximum lateral distance between corresponding seismic sensors is determined that will result in a contribution sum above a selected threshold.
    Type: Application
    Filed: March 24, 2009
    Publication date: November 12, 2009
    Inventors: David Monk, Paul Young
  • Chemo-selective identification of therapeutics
    Publication number: 20090192046
    Abstract: Disclosed is the use of a therapeutic filter for simultaneous screening against multiple targets coupled with subsequent in silico drug discovery utilizing biologically active compounds for the identification and selection of gene sets having characteristic expression profiles for formation of an active compound database with subsequent identification of therapeutically effective agents by scanning and matching in said active compound database.
    Type: Application
    Filed: July 9, 2007
    Publication date: July 30, 2009
    Inventors: Daniel R. Soppet, Stephen K. Horrigan, Paul Young, James Meade
  • Hydroxypiperidine Derivatives and Uses Thereof
    Publication number: 20090036429
    Abstract: Chemical agents, such as derivatives of hydroxypiperidine moieties, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, especially where such agents modulate the activity of enzymes and structural polypeptides present in cells, such as cancer cells, or where the agents modulate levels of gene expression in cellular systems, including cancer cells, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents.
    Type: Application
    Filed: February 16, 2007
    Publication date: February 5, 2009
    Inventors: Norman E. Ohler, Jeffrey W. Watthey, Qin Zong, Paul Young, Kathryn J. Strand
  • Connective Tissue Growth Factor-4
    Publication number: 20090010847
    Abstract: The present invention relates to a novel human protein called Connective Tissue Growth Factor-4, and isolated polynucleotides encoding this protein. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to this novel human protein.
    Type: Application
    Filed: February 20, 2007
    Publication date: January 8, 2009
    Applicant: Human Genome Sciences, Inc.
    Inventors: Paul Young, Steven Ruben
  • COMPLIANCE CONTROL SYSTEM
    Publication number: 20080148346
    Abstract: A method comprises automatically obtaining network data, and automatically processing the network data to detect violation of a compliance control policy of an entity.
    Type: Application
    Filed: September 14, 2007
    Publication date: June 19, 2008
    Inventors: Ravinder Gill, Lee Cooper, Paul Young, Pankaj Srivastava, Boulos Aoun
  • Cancer gene determination and therapeutic screening using signature gene sets
    Publication number: 20080050379
    Abstract: Processes for assaying potential antitumor agents based on their modulation of the expression of specified genes, or sets, of suspected cancer cell genes are disclosed, along with methods for diagnosing cancerous, or potentially cancerous, conditions as a result of the expression, or patterns of expression, of such genes, or sets of genes. Also disclosed are methods for determining functionally related genes, or gene sets, as well as methods for treating cancer based on targeting expression products of such genes, or gene sets, and determining genes involved in the cancerous process.
    Type: Application
    Filed: July 26, 2007
    Publication date: February 28, 2008
    Inventors: Paul Young, Meena Augustus, Kenneth Carter, Reinhard Ebner, Gregory Endress, Stephen Horrigan, Daniel Soppet, Zoe Weaver
  • 98 Human Secreted Proteins
    Publication number: 20080051338
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 12, 2007
    Publication date: February 28, 2008
    Applicant: Human Genome Sciences, Inc.
    Inventors: George Komatsoulis, Craig Rosen, Steven Ruben, Roxanne Duan, Paul Moore, Yanggu Shi, David LaFleur, Ying-Fei Wei, Jian Ni, Kimberly Florence, Paul Young, Laurie Brewer, Daniel Soppet, Gregory Endress, Reinhard Ebner, Henrik Olsen, Michael Mucenski
  • Cancer-linked genes as targets for chemotherapy
    Publication number: 20080025981
    Abstract: Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with methods for assaying for potential antitumor agents based on their modulation of the expression of these cancer-related genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing cancer using the gene sequences as well as the polypeptide sequences.
    Type: Application
    Filed: November 15, 2006
    Publication date: January 31, 2008
    Inventors: Paul Young, Reinhard Ebner, Zoe Weaver, Jeffrey Strovel, Stephen Horrigan, Martin Shea, Bernd Weigle, Michael Rieger, Jennifer Rick, Colyn Cain
  • Identification of Therapeutic Agents Using Genetic Fingerprinting
    Publication number: 20070270504
    Abstract: Methods for identifying compounds having similar biological activity based on similarity in genetic expression profile in cells contacted with one or more of said compounds, along with specifically identified compounds, are disclosed.
    Type: Application
    Filed: June 17, 2004
    Publication date: November 22, 2007
    Applicant: AVALON PHARMACEUTICALS, INC.
    Inventors: Paul Young, Qin Zong, Stephen Horrigan
  • 70 Human Secreted Proteins
    Publication number: 20070238664
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: May 22, 2007
    Publication date: October 11, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Craig Rosen, Carrie Fischer, Daniel Soppet, Kenneth Carter, Daniel Bednarik, Gregory Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul Young, John Greene, Ann Ferrie, Roxanne Duan, Jing-Shan Hu, Kimberly Florence, Henrik Olsen, Reinhard Ebner, Laurie Brewer, Yanggu Shi
  • Connective Tissue Growth Factor-4
    Publication number: 20070224121
    Abstract: The present invention relates to a novel human protein called Connective Tissue Growth Factor-4, and isolated polynucleotides encoding this protein. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to this novel human protein.
    Type: Application
    Filed: February 20, 2007
    Publication date: September 27, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Paul Young, Steven Ruben
  • 28 HUMAN SECRETED PROTEINS
    Publication number: 20070203070
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: May 4, 2007
    Publication date: August 30, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Craig Rosen, Steven Ruben, Yi Li, Zhizhen Zeng, Hla Kyaw, Carrie Fischer, Haodong Li, Daniel Soppet, Reiner Gentz, Ying-Fei Wei, Paul Moore, Paul Young, John Greene, Ann Ferrie, Gregg Hastings
  • 31 Human Secreted Proteins
    Publication number: 20070190612
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: April 23, 2007
    Publication date: August 16, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steven Ruben, Craig Rosen, Reinhard Ebner, Kimberly Florence, Paul Young, Charles Birse, Kenneth Carter, George Komatsoulis
  • Chemo-centric selection of disease-related genetic profiles
    Publication number: 20070184447
    Abstract: Methods for the identification of disease-related gene sets and expression nprofiles, based on common chemical modulation using a specific chemical compound are disclosed.
    Type: Application
    Filed: February 24, 2005
    Publication date: August 9, 2007
    Inventors: Jeffrey Strovel, David Bol, Paul Young
  • ANTIBODIES TO HHPEN62 POLYPEPTIDE
    Publication number: 20070172830
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: May 21, 2004
    Publication date: July 26, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Kimberly Florence, Jian Ni, Craig Rosen, Kenneth Carter, Paul Moore, Henrik Olsen, Yanggu Shi, Paul Young, Ying-Fei Wei, Laurie Brewer, Daniel Soppet, David LaFleur, Gregory Endress, Reinhard Ebner, Charles Birse
  • Delivery device for a powder aerosol
    Publication number: 20070151560
    Abstract: The invention provides a delivery device (10) for a medicament comprising: a housing (50), a receptacle (54) holding a medicament (80) in the form of a powder; and a source of propellant (53), characterized in that the housing (50) provides an inlet (63) and an outlet (56) for the receptacle (54) wherein the inlet (63) is in fluid communication with the source of propellant (53) and is directed against the medicament (80) and the outlet (56) is spaced from the medicament (80) to allow aerosolisation of the medicament (80); the device (10) provides improved delivery efficiency, particularly a delivered fine particle fraction of greater than 20% by weight.
    Type: Application
    Filed: June 14, 2004
    Publication date: July 5, 2007
    Inventors: Robert Price, John Stanifort, Derek Woodcock, Paul Young
  • 87 Human Secreted Proteins
    Publication number: 20070154912
    Abstract: The present invention relates to 87 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: December 4, 2006
    Publication date: July 5, 2007
    Applicant: Human Genome Sciences, Inc.
    Inventors: Paul Young, John Greene, Ann Ferrie, Steven Ruben, Craig Rosen, Roxanne Duan, Jing-Shan Hu, Kimberly Florence, Henrik Olsen, Reinhard Ebner, Laurie Brewer, Paul Moore, Yanggu Shi, David LaFleur, Jian Ni
  • Delivery device for a powder aerosol
    Publication number: 20070056586
    Abstract: A delivery device for a medicament including: a housing, a receptacle holding a medicament in the form of a power; and a source of propellant, wherein the housing provides an inlet and an outlet for the receptacle, wherein the inlet is in fluid communication with the source of propellant and is directed against the medicament and the outlet is spaced from the medicament to allow aerosolization of the medicament; the device provides improved delivery efficiency, particularly a delivered fine particle fraction of greater than 20% by weight.
    Type: Application
    Filed: April 21, 2006
    Publication date: March 15, 2007
    Inventors: Robert Price, John Staniforth, Derek Woodcock, Paul Young, James Byrnes, J. Cogburn, Douglas Dockhorn, Robert Dockhorn, Edgar Mitchell, Susan Prather