Patents by Inventor Pei-Ying Lin

Pei-Ying Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11214774
    Abstract: The present disclosure includes a PINK1-C-terminal domain (PINK1-CTD) polypeptide that binds to ERBB tyrosine kinase domain (ERBB-TKD) and therefore impedes ERBB from dimerization and activation. The PINK1-CTD polypeptide inhibits, prevents and/or treats ERBB-expressing cancers. The disclosure demonstrates the anti-tumor function of the PINK1-CTD, which provides a new direction for ERBB-expressing cancer therapy.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: January 4, 2022
    Assignees: National Taiwan University, Academia Sinica
    Inventors: Pan-Chyr Yang, Pei-Ying Lin, Bo-Tsang Huang
  • Patent number: 10866281
    Abstract: A diagnostic system includes: a processor, arranged to extract a plurality of coordinates of a plurality of pins on an outer surface of a design layout according to a plurality of tagging texts labeling the plurality of pins respectively, and arranged to generate a design exchange format file according to the plurality of coordinates, wherein an order of the plurality of tagging texts are sorted by a predetermined scanning sequence; and a chip diagnostic tool, arranged to scan the plurality of scan components in a physical circuit on a testing platform through the plurality of pins on the outer surface of the physical circuit by following the predetermined scanning sequence to determine a defect component in the physical circuit according to the design exchange format file; wherein the physical circuit corresponds to the design layout.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: December 15, 2020
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD.
    Inventors: Wei-Pin Changchien, Hong-Chen Cheng, Pei-Ying Lin, Hsin-Wu Hsu
  • Publication number: 20200178684
    Abstract: The present invention is related to an adjustable desk, which includes a long desktop, a slide rail mounted on the bottom surface of the desktop along the length direction thereof, and a sliding member slidably arranged in the slide rail, which comprises a connector connected with the sliding member, and a replaceable and detachable office furniture unit, such as keyboard holder, drawer cabinet, and etc., connected with the connector of the sliding member. In this way, when the user changes his/her seating position or use of the desk, the sliding members allow the office furniture units, such as the keyboard holder, the drawer cabinet, and etc., to be moved along the slide rails along the length direction of the desktop or replaced, so as for flexibly adjusting the keyboard holder and drawer cabinet to the user's new seating position in order to allow the user to operate the keyboard or to reach the drawer cabinet without being limited in a certain location at the desk for work.
    Type: Application
    Filed: December 5, 2019
    Publication date: June 11, 2020
    Inventor: Pei Ying Lin
  • Publication number: 20200063181
    Abstract: A fluorescent probe is obtained via hydrolysis and condensation reaction using 3-glycidoxypropyl trimethoxysilane. The fluorescent probe includes a silicon oxide core and a self-assembled monolayer. The self-assembled monolayer has an epoxide group, and joins the silicone oxide core by a covalent bond. The epoxide group of the fluorescent probe can form a conjugated bond with a molecule with an amino group via an aminolysis reaction, forming a nanoparticle including the molecule and the fluorescent probe.
    Type: Application
    Filed: October 28, 2019
    Publication date: February 27, 2020
    Inventors: SHU-CHEN HSIEH, PEI-YING LIN
  • Publication number: 20190242943
    Abstract: A diagnostic system includes: a processor, arranged to extract a plurality of coordinates of a plurality of pins on an outer surface of a design layout according to a plurality of tagging texts labeling the plurality of pins respectively, and arranged to generate a design exchange format file according to the plurality of coordinates, wherein an order of the plurality of tagging texts are sorted by a predetermined scanning sequence; and a chip diagnostic tool, arranged to scan the plurality of scan components in a physical circuit on a testing platform through the plurality of pins on the outer surface of the physical circuit by following the predetermined scanning sequence to determine a defect component in the physical circuit according to the design exchange format file; wherein the physical circuit corresponds to the design layout.
    Type: Application
    Filed: April 19, 2019
    Publication date: August 8, 2019
    Inventors: WEI-PIN CHANGCHIEN, HONG-CHEN CHENG, PEI-YING LIN, HSIN-WU HSU
  • Patent number: 10267853
    Abstract: A diagnostic system includes a location extractor, a file generator, and a chip diagnostic tool. The location extractor is arranged to extract at least a coordinate of at least one component in an intellectual property design layout of an integrated circuit design layout according to at least one tagging text labeling the at least one component in the intellectual property design layout. The file generator is arranged to generate a format file according to the at least coordinate. The chip diagnostic tool is arranged to scan a physical intellectual property circuit in a physical integrated circuit to determine a defect component in the physical intellectual property circuit according to the format file. The physical intellectual property circuit corresponds to the intellectual property design layout, and the physical integrated circuit corresponds to the integrated circuit design layout.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: April 23, 2019
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD.
    Inventors: Wei-Pin Changchien, Hong-Chen Cheng, Pei-Ying Lin, Hsin-Wu Hsu
  • Publication number: 20180327808
    Abstract: A nanodot for detecting glucose concentration includes a silicon oxide core, a self-assembled monolayer having a 3-glycidoxypropyl trimethoxysilane group, and a glucose oxidase particle. The self-assembled monolayer joins the silicon oxide core by a covalent bond, and the glucose oxidase particle joins the 3-glycidoxypropyl trimethoxysilane group of the self-assembled monolayer by a conjugated bond. Moreover, a method for detecting glucose concentration by the nanodot includes oxidizing a glucose molecule in a glucose solution by the glucose oxidase particle of the nanodot, producing a hydrogen peroxide molecule; fluorescent quenching the nanodot by the hydrogen peroxide molecule, resulting in a change in fluorescent intensity of the nanodot; and detecting the change in fluorescent intensity of the nanodot.
    Type: Application
    Filed: June 14, 2017
    Publication date: November 15, 2018
    Inventors: SHU-CHEN HSIEH, PEI-YING LIN
  • Publication number: 20180112192
    Abstract: The present disclosure includes a PINK1-C-terminal domain (PINK1-CTD) polypeptide that binds to ERBB tyrosine kinase domain (ERBB-TKD) and therefore impedes ERBB from dimerization and activation. The PINK1-CTD polypeptide inhibits, prevents and/or treats ERBB-expressing cancers. The disclosure demonstrates the anti-tumor function of the PINK1-CTD, which provides a new direction for ERBB-expressing cancer therapy.
    Type: Application
    Filed: May 2, 2016
    Publication date: April 26, 2018
    Inventors: Pan-Chyr Yang, Pei-Ying Lin, Bo-Tsang Huang
  • Publication number: 20170176525
    Abstract: A diagnostic system includes a location extractor, a file generator, and a chip diagnostic tool. The location extractor is arranged to extract at least a coordinate of at least one component in an intellectual property design layout of an integrated circuit design layout according to at least one tagging text labeling the at least one component in the intellectual property design layout. The file generator is arranged to generate a format file according to the at least coordinate. The chip diagnostic tool is arranged to scan a physical intellectual property circuit in a physical integrated circuit to determine a defect component in the physical intellectual property circuit according to the format file. The physical intellectual property circuit corresponds to the intellectual property design layout, and the physical integrated circuit corresponds to the integrated circuit design layout.
    Type: Application
    Filed: April 25, 2016
    Publication date: June 22, 2017
    Inventors: WEI-PIN CHANGCHIEN, HONG-CHEN CHENG, PEI-YING LIN, HSIN-WU HSU
  • Publication number: 20160331721
    Abstract: The present invention provides a composition for alleviating and preventing Alzheimer's disease. This composition comprises at least one yellow pigment extracted from a red mold product, and the said yellow pigment is Monascin or Ankaflavin. Moreover, after completing a variety of experiments, the composition has been proved possessing effects on alleviating and preventing AD by alleviating the symptoms of memory loss and learning disability resulted from the ?-amyloid accumulated in brain of rats as well as reducing the inflammation and the oxidative stress caused by the ?-amyloid in cerebral cortex and hippocampus tissue. Therefore, the experimental results have proved that this novel composition is indeed able to treat and prevent Alzheimer's disease.
    Type: Application
    Filed: April 26, 2016
    Publication date: November 17, 2016
    Inventors: TZU-MING PAN, Chun-Lin LEE, Pei-Ying Lin, Ya-Wen HSU
  • Patent number: 9303049
    Abstract: The present disclosure provides a method for manufacturing a nanodot, including: providing a hydrolysable silane, wherein the hydrolysable silane has one or more hydrolysable groups and one or more substituted or non-substituted hydrocarbon groups; and performing a one-step heat treatment to hydrolyze and condensate the hydrolysable silane to form a nanodot. The nanodot includes: a core, the core is selected from the group consisting of a semiconductor core or a metal core; and a self-assembled monolayer (SAM) including the substituted or non-substituted hydrocarbon groups, wherein the self-assembled monolayer is connected to the core by covalent bonds.
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: April 5, 2016
    Assignee: NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Shu-Chen Hsieh, Pei-Ying Lin
  • Publication number: 20150073167
    Abstract: The present disclosure provides a method for manufacturing a nanodot, including: providing a hydrolysable silane, wherein the hydrolysable silane has one or more hydrolysable groups and one or more substituted or non-substituted hydrocarbon groups; and performing a one-step heat treatment to hydrolyze and condensate the hydrolysable silane to form a nanodot. The nanodot includes: a core, the core is selected from the group consisting of a semiconductor core or a metal core; and a self-assembled monolayer (SAM) including the substituted or non-substituted hydrocarbon groups, wherein the self-assembled monolayer is connected to the core by covalent bonds.
    Type: Application
    Filed: June 2, 2014
    Publication date: March 12, 2015
    Applicant: National Sun Yat-sen University
    Inventors: Shu-Chen HSIEH, Pei-Ying LIN
  • Patent number: 8384430
    Abstract: A die includes a plurality of through-substrate vias (TSVs) penetrating a substrate of the die, wherein the plurality of TSVs are grouped as a plurality of TSV pairs. A plurality of contact pads is coupled to the plurality of TSVs, wherein the plurality of contact pads is exposed on a first surface of the die. The die further includes a plurality of balanced pulse comparison units, wherein each of the plurality of balanced pulse comparison units includes a first input and a second input coupled to a first TSV and a second TSV of one of the plurality of TSV pairs. The die further includes a plurality of pulse latches, each including an input coupled to an output of one of the plurality of balanced pulse comparison units.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: February 26, 2013
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Nan-Hsin Tseng, Chin-Chou Liu, Wei-Pin Changchien, Pei-Ying Lin, Ta-Wen Hung
  • Patent number: 8127945
    Abstract: Disclosed is a vertical tool rack storage device which includes a hollow upright pivot shaft, a plurality of flat tool racks for holding tool bits and parts, and a plurality of connectors for pivotally coupling the flat tool racks to the hollow upright pivot shaft for enabling the tool racks to be arranged in a stack and individually turnable about the hollow upright pivot shaft.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: March 6, 2012
    Assignee: Steelworks Hardware, LLC
    Inventors: Chanwa Nguy, Pei-Ying Lin
  • Publication number: 20120038388
    Abstract: A die includes a plurality of through-substrate vias (TSVs) penetrating a substrate of the die, wherein the plurality of TSVs are grouped as a plurality of TSV pairs. A plurality of contact pads is coupled to the plurality of TSVs, wherein the plurality of contact pads is exposed on a first surface of the die. The die further includes a plurality of balanced pulse comparison units, wherein each of the plurality of balanced pulse comparison units includes a first input and a second input coupled to a first TSV and a second TSV of one of the plurality of TSV pairs. The die further includes a plurality of pulse latches, each including an input coupled to an output of one of the plurality of balanced pulse comparison units.
    Type: Application
    Filed: December 17, 2010
    Publication date: February 16, 2012
    Applicant: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Nan-Hsin Tseng, Chin-Chou Liu, Wei-Pin Changchien, Pei-Ying Lin, Ta-Wen Hung
  • Patent number: 8104620
    Abstract: A magnetic sweeper configured to collect magnetic metal debris, such as nails, screws, sheet metal fragments, staples, rivets and the like from a surface, and to permit easy removal of the collected debris from the sweeper is disclosed. The sweeper comprises a non-metallic body, a permanent magnet disposed within the body, a non-metallic cover hingably mounted to the underside of the body and an integrated latch configured to removably secure the cover to the body. The sweeper is configured to removably engage a handle for controlling the sweeper, and in another embodiment, an extendable, telescoping extender may be connected between the coupler and the handle to permit the sweeper to be used in a wide variety of locations. Preferably, the sweeper body is configured to swivel upon application of torque to the handle. In use, the sweeper is passed over metallic debris using the handle to guide the body.
    Type: Grant
    Filed: September 28, 2006
    Date of Patent: January 31, 2012
    Assignee: Steelworks Hardware, LLC
    Inventors: Pei-Ying Lin, Chanwa Nguy
  • Patent number: 8061536
    Abstract: Disclosed is a tool box set fastener, which include a first fastening structure, which has mounting base fixedly fastened to a vertical wall or upright support and a coupling unit formed integral with the mounting base, and a second fastening structure, which is connectable to a tool box set to secure the tool box set to the first fastening structure and has a coupling base connectable to the coupling unit of the first fastening structure.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: November 22, 2011
    Assignee: Steelworks Hardware, LLC
    Inventors: Pei-Ying Lin, Chanwa Nguy
  • Patent number: 8002124
    Abstract: Disclosed is a tool rack set fastener, which includes a first fastening structure, which has mounting base fixedly fastened to a vertical wall or upright support and a coupling unit formed integral with the mounting base, and a second fastening structure, which is connectable to a tool rack set to secure the tool rack set to the first fastening structure and has a coupling base connectable to the coupling unit of the first fastening structure.
    Type: Grant
    Filed: April 26, 2005
    Date of Patent: August 23, 2011
    Assignee: Steelworks Hardware, LLC
    Inventors: Pei-Ying Lin, Chanwa Nguy
  • Patent number: 7975855
    Abstract: A tool storage device includes comprises a hollow upright pivot shaft end capped at the top and bottom ends. Fastening and coupling structures are attached to the end caps. These have apertures, which are used to fasten the tool storage device to an upright surface, such as a wall.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: July 12, 2011
    Assignee: Steelworks Hardware, LLC
    Inventors: Pei-Ying Lin, Chanwa Nguy
  • Patent number: 7967355
    Abstract: The tool storage device includes a base having a top side, a bottom side, and a hollow upright pivot shaft with two ends. At the top end of the hollow upright pivot shaft is an end cap having a plughole and a connecting mechanism. The bottom end of the hollow upright pivot shaft is attached to the top side of the base. The bottom side of the base has a pole cover containing a plughole for receiving a connecting structure. Fastening structures are provided to facilitate fastening of the vertical tool storage device to a structure, such as a wall. The end cap and the pole cover of the tool storage device enable the vertical tool storage device to be connected to a fastening and connecting structure.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: June 28, 2011
    Assignee: Steelworks Hardware, LLC
    Inventors: Pei-Ying Lin, Chanwa Nguy