Publication number: 20250017913
Abstract: The present application relates to the field of pharmaceutical preparations and relates to [1,2,4]triazolo [1,5-a]pyridine compounds and their isomers or pharmaceutically acceptable salts or their crystal forms, as well as local topical preparations and their applications in skin diseases. Specifically, it relates to a local topical formulations of compound (S)—N-(5-(2-(2,2-difluorocyclopropanecarbonyl)-2-nitrospiro[3.5]non-7-yl)-[1,2,4-triazole[1,5-a]pyridine-2-yl) cyclopropaneformamide and its isomers or pharmaceutically acceptable salts or crystal forms, and their applications in skin diseases. The preferred skin diseases include psoriasis, atopic dermatitis, vitiligo, lupus erythematosus, alopecia areata, eczema, contact dermatitis, urticaria, pompholyxs, dermatomyositis, scleroderma, acne, and seborrheic dermatitis.
Type:
Application
Filed:
August 18, 2022
Publication date:
January 16, 2025
Applicant:
ZHUHAI UNITED LABORATORIES CO., LTD.
Inventors:
Meiyue SHEN, Liwei MU, Tingting YU, Yujun HE, Chong SU, Peng GAO, Zheng WANG, Degang WANG