Abstract: The present disclosure relates in some aspects to immunogenic compositions including recombinant peptides and proteins comprising coronavirus viral antigens and immunogens, e.g., coronavirus S protein peptides. In some aspects, the immunogenic composition comprises a secreted fusion protein comprising a soluble coronavirus viral antigen joined by in-frame fusion to a C-terminal portion of a collagen which is capable of self-trimerization to form a disulfide bond-linked trimeric fusion protein. In some aspects, the immunogenic compositions provided herein are useful for generating an immune response, e.g., for treating or preventing a coronavirus infection. In some aspects, the immunogenic compositions provided herein may be used in a vaccine composition, e.g., as part of a prophylactic and/or therapeutic vaccine. Also provided herein are methods for producing the recombinant peptides and proteins, prophylactic, therapeutic, and/or diagnostic methods, and related kits.

Abstract: A dimming module and method for manufacturing the same, and a dimming glass, relate to the field of smart glass technology. The dimming module includes: a first dimming structure (10) and a second dimming structure (20). Each of the first dimming structure (10) and the second dimming structure (20) includes a first substrate (1), a second substrate (2) and a liquid crystal layer (3), and a first flexible circuit board (4) and a second flexible circuit board (5). The first substrate (1) is provided with a first binding area (11), and a first electrode (6) on one side facing the liquid crystal layer (3). The second substrate (2) is provided with a second binding area (21), and a plurality of second electrodes (7) on one side facing the liquid crystal layer (3).

Abstract: A light adjustment device includes a first substrate and a second substrate that are arranged opposite to each other, a light adjustment module, and an ultraviolet light blocking layer. The light adjustment module is located between the first substrate and the second substrate. The ultraviolet light blocking layer is located between the first substrate and the light adjustment module or located inside the light adjustment module. A refractive index of the ultraviolet light blocking layer is greater than a refractive index of the first substrate.

Abstract: The present disclosure provides a dimming glass and a method for manufacturing the dimming glass. The dimming glass includes: at least one dimming functional layer sandwiched between two glass substrates, where a plurality of conductive leads is connected to a bonding circuit board, and a sealant filled between sealant regions of the two glass substrates. Each conductive lead includes a connecting end, a protruding end and an extension segment. The connecting end is connected to the bonding circuit board, the protruding end extends out of an outer side of an edge of the glass substrate, at least a part of the extension segment extends in a first direction which is an extension direction of an edge of the bonding side of the dimming functional layer, and the extension segment is located in the sealant region and is secured through the sealant.

Abstract: A light-adjusting glass is provided to include: a first toughened glass layer, a first adhesive layer, a first substrate, a second substrate, a second adhesive layer, a second toughened glass layer and supporting spacers between the first and second substrates, which are sequentially stacked; materials of the first and second adhesive layers are melted under the conditions that a temperature is in a range of 130° C. to 150° C. and a pressure is in a range of 12 bar to 14 bar, and are solidified after being cooled; the light-adjusting glass further includes an edge sealing structure around the first and second substrates, and the edge sealing structure, the first and second substrates are enclosed to form a gap filled with a liquid crystal; the edge sealing structure includes a liquid crystal pouring port therein; a sealing glue is at an opening of the liquid crystal pouring port and seals the opening.

Abstract: The present disclosure provides a method for preparing a catalyst for pyrolysis of waste plastics to produce oil, comprising: washing and modifying coal gangue powder with acid, and then placing in an alkaline solution, etching under magnetic stirring for 20-30 minutes, and washing with water until neutral; placing the catalyst washed until neutral in a metal solution, loading the metal by impregnation, and then filtering and washing; then placing the catalyst in the molding machine and adding adhesive and water, to compress into a suitable shape, drying, and finally calcinating to activate to obtain a product. The present disclosure not only solves the problem of waste plastic pollution, but also obtains fuel oil with high valuable products while reducing the cost of waste plastic treatment, and also improves the yield of fuel oil.

Abstract: A machine for smashing thermosetting materials includes a high-pressure direct drive pump assembly, a mixing tank, a chemical solution tank, a hydraulic-control solenoid valve, a low-pressure auxiliary pump, a directional valve set and a controller. The controller, connected signally with the high-pressure direct drive pump assembly, the mixing tank, the chemical solution tank, the hydraulic-control solenoid valve, the low-pressure auxiliary pump and the directional valve set, is used to control opens and closes of the first directional valve, the second directional valve, the third directional valve and the hydraulic-control solenoid valve so as to supply the chemical solution in the chemical solution tank to the mixing tank.

Abstract: The present disclosure provides a dimming glass and a method for manufacturing the dimming glass. The dimming glass includes: at least one dimming functional layer sandwiched between two glass substrates, where a plurality of conductive leads is connected to a bonding circuit board, and a sealant filled between sealant regions of the two glass substrates. Each conductive lead includes a connecting end, a protruding end and an extension segment. The connecting end is connected to the bonding circuit board, the protruding end extends out of an outer side of an edge of the glass substrate, at least a part of the extension segment extends in a first direction which is an extension direction of an edge of the bonding side of the dimming functional layer, and the extension segment is located in the sealant region and is secured through the sealant.

Abstract: A dimming window and a manufacturing method thereof, belong to the technical field of dimming glass. The dimming window includes: at least two chambers arranged in a stack, each of the chambers comprising two light-transmitting substrates arranged opposite to each other; the at least two chambers include a first chamber and a second chamber, a dinning structure is provided in the first chamber, and a first reflective film is provided in the first chamber and/or the second chamber; wherein the thickness of the second chamber is greater than or equal to the thickness of the first chamber, and the thickness of the chamber is a distance between two opposite surfaces of the two light-transmitting substrates of the chamber. The technical solution of the present disclosure can improve the shading effect of the dimming window.

Abstract: Compositions of TNF family of cytokines in covalently linked trimeric forms are disclosed. The resulting fusion proteins are secreted as disulfide bond—linked homotrimers, which are more stable in structure and therapeutically more efficacious than their native counterparts.

Abstract: The recombinant peptides and proteins having thrombopoietin (TPO) activities, e.g., thrombopoietin mimetic peptides that are TPO receptor (TPOR) agonists. The recombinant peptides or proteins include a recombinant human p75 TNF receptor and TPO mimetic peptides linked by an Fc fragment of IgG1. The recombinant peptides form a homodimer by inter-chain disulfide bond in the Fc region and include six TPOR binding and/or activating domain in the C-terminus. The recombinant peptides or proteins provided herein are useful for increasing platelet count, e.g., for treating thrombocytopenia. The methods for producing the recombinant peptides and proteins, formulations, and therapeutic methods.

Abstract: Disclosed herein are a process of preparing a polyurethane elastomer foam, a polyurethane elastomer foam prepared by the process, and a method of using the polyurethane elastomer foam.

Abstract: The present disclosure provides methods and compositions for affinity purification of proteins containing a C-terminal polypeptide sequence of a procollagen, such as trimeric fusion proteins. Also provided are polypeptides, fusion proteins, and recombinant polypeptides containing an Endo 180 ecto-domain or portion thereof capable of reversibly binding a C-terminal polypeptide sequence of a procollagen. Also provided are articles of manufacture, kits, and apparatus related to the Endo 180 ecto-domain polypeptides.

Abstract: A dimming module and method for manufacturing the same, and a dimming glass, relate to the field of smart glass technology. The dimming module includes: a first dimming structure (10) and a second dimming structure (20). Each of the first dimming structure (10) and the second dimming structure (20) includes a first substrate (1), a second substrate (2) and a liquid crystal layer (3), and a first flexible circuit board (4) and a second flexible circuit board (5). The first substrate (1) is provided with a first binding area (11), and a first electrode (6) on one side facing the liquid crystal layer (3). The second substrate (2) is provided with a second binding area (21), and a plurality of second electrodes (7) on one side facing the liquid crystal layer (3).

Abstract: The present disclosure provides a dimming substrate, a manufacturing method of the dimming substrate, a dimming structure and a dimming module, and relates to the technical field of display. According to the present disclosure, a bonding layer, a flexible base plate, an electrode layer and an orientation layer are sequentially arranged on a rigid carrier plate, and the bonding layer includes one or more adhesive layers. By removing flexible base films from the bonding layer, the bonding layer only includes one or more adhesive layers, such that the dimming substrate includes less flexible base films.

Abstract: A semiconductor device includes a conductive can include a flat portion and at least one peripheral rim portion extending from an edge of the flat portion, a semiconductor die comprising a first main face and a second main face opposite to the first main face, a first contact pad disposed on the first main face and a second contact pad disposed on the second main face, wherein the first contact pad is electrically connected to the flat portion of the can, an electrical interconnector connected with the second contact pad, and an encapsulant disposed under the semiconductor die so as to surround the electrical interconnector, wherein an external surface of the electrical interconnector is recessed from an external surface of the encapsulant.

Abstract: An inner frame of a door or a window is disclosed. The inner frame is disposed at an inner side of a window sash, and is connected between a jamb of the door or the window sash and a door frame or a window frame. The inner frame includes a fixing portion for fixing to the jamb, a water baffle, and a connecting portion for connecting with the door frame or the window frame. One side of the fixing portion is fixed to the jamb, the water baffle is integrally disposed on the other side of the fixing portion opposite to the one side, and the connecting portion is integrally disposed on a side of the water baffle facing away from the fixing portion and is connected to the door frame or the window frame.

Abstract: Described herein is a method for producing a PU foam insole, including the following steps of: (1) pouring the raw materials used to form a PU foam into a mould, reacting to obtain a PU sheet, where the height of the mould cavity is from about 1.0 to about 1.6 times of the total thickness of two finished insoles; (2) splitting the PU sheet into two halves in the horizontal direction to obtain two pieces of PU insole material, where one surface of the material has open pores, and the other surface of the material has a skin; and (3) attaching a piece of fabric onto the surface having open pores of the material obtained in step (2). Also described herein is a PU foam insole produced by the method.

Abstract: A process diagnosis system includes a digital twin calculation unit, a process diagnosis calculation unit, and a remote calculation analysis unit. The digital twin calculation unit obtains a vibration-related parameter and a cutting-related parameter of a processing device, and performs a simulation calculation for the vibration-related parameter, the cutting-related parameter and a three-dimensional model corresponding to the processing device to generate a three-dimensional calculation result. The process diagnosis calculation unit receives a three-dimensional calculation result and displays the three-dimensional calculation result. The remote calculation analysis unit receives the three-dimensional calculation result, and performs a simulation analysis for the three-dimensional calculation result to generate an analysis result.