Abstract: A process diagnosis system includes a digital twin calculation unit, a process diagnosis calculation unit, and a remote calculation analysis unit. The digital twin calculation unit obtains a vibration-related parameter and a cutting-related parameter of a processing device, and performs a simulation calculation for the vibration-related parameter, the cutting-related parameter and a three-dimensional model corresponding to the processing device to generate a three-dimensional calculation result. The process diagnosis calculation unit receives a three-dimensional calculation result and displays the three-dimensional calculation result. The remote calculation analysis unit receives the three-dimensional calculation result, and performs a simulation analysis for the three-dimensional calculation result to generate an analysis result.

Abstract: Compositions of TNF family of cytokines in covalently linked trimeric forms are disclosed. The resulting fusion proteins are secreted as disulfide bond—linked homotrimers, which are more stable in structure and therapeutically more efficacious than their native counterparts.

Abstract: Provided are immunogenic compositions including recombinant peptides and proteins comprising respiratory syncytial virus (RSV) viral antigens and immunogens, e.g., RSV F protein peptides. The immunogenic composition comprises a secreted fusion protein comprising a soluble RSV viral antigen joined by in-frame a disulfide bond-linked trimeric fusion protein. The immunogenic compositions are useful for generating an immune response, e.g., for treating or preventing an RSV infection. The immunogenic compositions may be used in a vaccine composition, e.g., as part of a prophylactic and/or therapeutic vaccine. Also provided herein are methods for producing the recombinant peptides and proteins, prophylactic, therapeutic, and/or diagnostic methods, and related kits.

Abstract: The present disclosure discloses recombinant peptides and proteins comprising coronavirus viral antigens and immunogens, e.g., coronavirus S protein peptides, useful for analyzing an analyte such as neutralizing antibodies. In some aspects, the recombinant peptides and proteins comprise a secreted fusion protein comprising a soluble coronavirus viral antigen joined by in-frame fusion to a C-terminal portion of a collagen which is capable of self-trimerization to form a disulfide bond-linked trimeric fusion protein. Diagnostic methods and related kits are also disclosed.

Abstract: The present invention discloses immunogenic compositions including recombinant peptides and proteins comprising human immunodeficiency viruses (HIV) antigens and immunogens, e.g., gp 120 protein peptides. In some aspects, the immunogenic composition comprises a secreted fusion protein comprising a soluble HIV viral antigen joined by in-frame fusion to a C-terminal portion of a collagen which is capable of self-trimerization to form a disulfide bond-linked trimeric fusion protein. In some aspects, the immunogenic compositions provided herein are useful for generating an immune response, e.g., for treating or preventing an HIV infection. In some aspects, the immunogenic compositions provided herein may be used in a vaccine composition, e.g., as part of a prophylactic and/or therapeutic vaccine. Also provided herein are methods for producing the recombinant peptides and proteins, prophylactic, therapeutic, and/or diagnostic methods, and related kits.

Abstract: Provided are immunogenic compositions comprising a secreted fusion protein, wherein the secreted fusion protein comprises a soluble influenza or rabies viral antigen joined by in-frame fusion to a C-terminal portion of a collagen which is capable of self-trimerization to form a disulfide bond-linked trimeric fusion protein. Also provided are uses of the immunogenic compositions for generating an immune response against influenza or rabies infection and in a vaccine composition. Also provided are methods for producing the recombinant peptides and proteins, prophylactic, therapeutic, and/or diagnostic methods, and related kits.

Abstract: The present disclosure relates to the field of carbonaceous composite materials, in particular to a silicon-carbon composite material and a preparation method and a use thereof. The silicon-carbon composite material comprises a composite carbon material and nanometer silicon dispersed therein, wherein the composite carbon material is consisting of a graphitic crystal phase and an amorphous carbon phase, wherein the ratio I002/Iamor of the peak intensity I002 of the graphite crystal phase (002) plane relative to the peak intensity Iamor of the amorphous carbon phase as measured by the X-Ray Diffraction (XRD) is within a range of 0.1-40, the graphite crystalline phase is uniformly dispersed in the composite material, the dispersion coefficient ? of the ratio Id/Ig of Id and Ig as measured by Raman data is less than 0.8.

Abstract: A process diagnosis system includes a digital twin calculation unit, a process diagnosis calculation unit, and a remote calculation analysis unit. The digital twin calculation unit obtains a vibration-related parameter and a cutting-related parameter of a processing device, and performs a simulation calculation for the vibration-related parameter, the cutting-related parameter and a three-dimensional model corresponding to the processing device to generate a three-dimensional calculation result. The process diagnosis calculation unit receives a three-dimensional calculation result and displays the three-dimensional calculation result. The remote calculation analysis unit receives the three-dimensional calculation result, and performs a simulation analysis for the three-dimensional calculation result to generate an analysis result.

Abstract: The present disclosure relates in some aspects to immunogenic compositions including recombinant peptides and proteins comprising coronavirus viral antigens and immunogens, e.g., coronavirus S protein peptides. In some aspects, the immunogenic composition comprises a secreted fusion protein comprising a soluble coronavirus viral antigen joined by in-frame fusion to a C-terminal portion of a collagen which is capable of self-trimerization to form a disulfide bond-linked trimeric fusion protein. In some aspects, the immunogenic compositions provided herein are useful for generating an immune response, e.g., for treating or preventing a coronavirus infection. In some aspects, the immunogenic compositions provided herein may be used in a vaccine composition, e.g., as part of a prophylactic and/or therapeutic vaccine. Also provided herein are methods for producing the recombinant peptides and proteins, prophylactic, therapeutic, and/or diagnostic methods, and related kits.

Abstract: The disclosure discloses a catalyst capable of simultaneously removing COS and H2S in garbage gasification and a preparation method thereof, and belongs to the technical field of preparation of desulfurization catalysts. The method includes the following steps: pretreating an SBA-15 molecular sieve with a templating agent unremoved, which primarily includes the steps of removing the templating agent and introducing halogen atoms to modify the molecular sieve; then synthesizing an active component solution; and finally introducing active components into channels of the pretreated molecular sieve via surface tension by adopting an impregnation method, performing washing and drying, and performing calcining under an N2 atmosphere, so as to obtain the catalyst. The catalyst prepared according to the present disclosure can load the active components in fixed positions inside and outside the channels, and the components are easy to obtain, thereby having the advantages of low cost and good desulfurization effects.

Abstract: A switchable glass panel, a method of forming switchable glass panel and a method of forming switchable glass are provided. The method includes: forming a first electrode layer and a first alignment layer sequentially on a first substrate, and forming a second electrode layer and a second alignment layer sequentially on a second substrate; forming first sealants distributed along a first direction, second sealants distributed along a second direction and an edge sealant at the edge of the first alignment layer on the first alignment layer, where the first sealants and the second sealants form a grid with a plurality of openings; forming a plurality of liquid crystal layers corresponding to the plurality of openings on the second alignment layer; and oppositely arranging the first substrate and the second substrate to form a cell, and curing the first sealants and the second sealants.

Abstract: A motion control system and a motion control method are provided. The motion control method includes: sending a plurality of machining commands to a second controller by a first controller at a cloud; storing the plurality of machining commands in a buffer by the second controller; and operating the machine tool according to the plurality of machining commands stored in the buffer. As such, when poor communication occurs between the first controller and the second controller, the second controller causes the buffer to send a deceleration command to the machine tool so as to cause the machine tool to operate at a reduced speed, thereby avoiding unexpected motion such as sudden shutdown of the machine tool and damage to machined products.

Abstract: The disclosure discloses a catalyst capable of simultaneously removing COS and H2S in garbage gasification and a preparation method thereof, and belongs to the technical field of preparation of desulfurization catalysts. The method includes the following steps: pretreating an SBA-15 molecular sieve with a templating agent unremoved, which primarily includes the steps of removing the templating agent and introducing halogen atoms to modify the molecular sieve; then synthesizing an active component solution; and finally introducing active components into channels of the pretreated molecular sieve via surface tension by adopting an impregnation method, performing washing and drying, and performing calcining under an N2 atmosphere, so as to obtain the catalyst.

Abstract: A method for capturing a tool path, applicable to a machine tool having a controller and furnished with a tooling, includes the steps of: obtaining a data update frequency of the controller; calculating a feed rate of the controller, determining whether or not the feed rate is obtained, going to next step if positive, and going to the previous step if negative; reading G-codes of the controller to confirm the feed rate; and, based on the confirmed feed rate, recording machine coordinates transmitted from the controller for synthesizing a tool path file. The tool path file is used for simulation and analysis of machining of the machine tool. In addition, a device for capturing the tool path is also provided.

Abstract: Compositions of TNF family of cytokines in covalently linked trimeric forms are disclosed. The resulting fusion proteins are secreted as disulfide bond-linked homotrimers, which are more stable in structure and therapeutically more efficacious than their native counterparts.

Abstract: A switchable glass panel, a method of forming switchable glass panel and a method of forming switchable glass are provided. The method includes: forming a first electrode layer and a first alignment layer sequentially on a first substrate, and forming a second electrode layer and a second alignment layer sequentially on a second substrate; forming first sealants distributed along a first direction, second sealants distributed along a second direction and an edge sealant at the edge of the first alignment layer on the first alignment layer, where the first sealants and the second sealants form a grid with a plurality of openings; forming a plurality of liquid crystal layers corresponding to the plurality of openings on the second alignment layer; and oppositely arranging the first substrate and the second substrate to form a cell, and curing the first sealants and the second sealants.

Abstract: A shift register includes an input circuit, a compensation circuit, an output circuit, a pull-down control circuit, a pull-down circuit, and a reset circuit. During operation of a pixel driving circuit, if a display abnormality occurs in one or more pixels corresponding to the shift register, a compensation signal may be provided by the compensation circuit to a pull-up node according to specific condition of the display abnormality, so as to change a voltage of the pull-up node, and further change a delay time of waveform of the signal passing the switching element in the output circuit connected to the pull-up node.

Abstract: A high-barrier biodegradable Doypack and a preparation method therefor. The Doypack consists of two parts, a high-barrier biodegradable self-sealing strip and a five-layered composite high-barrier biodegradable Doypack body. The main base materials of the high-barrier biodegradable self-sealing strip are PLGA and PPC that have excellent barrier performance; and the five-layered composite high-barrier biodegradable Doypack body consists of single side glossy white Kraft paper, a bonding layer, a first barrier layer, a second barrier layer, and a heat-sealing layer, which are integrally formed by using a process combining four-layer co-extrusion and lamination. Compared to conventional non-degradable Doypacks, the high-barrier biodegradable Doypack is substantially equivalent in terms of the physical and mechanical performance and heat-sealing performance, but has a superior barrier performance, and is biodegradable.

Abstract: The present disclosure provides a dimming substrate, a manufacturing method of the dimming substrate, a dimming structure and a dimming module, and relates to the technical field of display. According to the present disclosure, a bonding layer, a flexible base plate, an electrode layer and an orientation layer are sequentially arranged on a rigid carrier plate, and the bonding layer includes one or more adhesive layers. By removing flexible base films from the bonding layer, the bonding layer only includes one or more adhesive layers, such that the dimming substrate includes less flexible base films.