Abstract: The present invention generally provides methods for the site-specific modification of peptides, polypeptides, and proteins, e.g., granulocyte macrophage colony-stimulating factor, human superoxide dismutase, annexin, leptin, antibodies and the like, cytokines and chemokines, at their N-termini and at sites at which unnatural aminoacids have been introduced along the protein framework. The modifications described herein can be used for the synthesis and application of the adducts in radio-labeling, molecular imaging and protein therapeutic applications, and the treatment of disorders such as rheumatoid arthritis, lupus erythematosus, psoriasis, multiple sclerosis, type-1 diabetes, Crohn's disease, and systemic sclerosis, Alzheimer disease, cancer, liver disease (e.g., alcoholic liver disease), and cachexia.

Abstract: An operation method to operate a tilt sensor with power-saving mechanism is provided. The operation method comprises the steps as follows. An accommodating space is provided such that a blocking object is displaceable in the accommodating space according to the gravity. A working mode is performed such that a light-emitting element emits light according to a first current and at least two first light sensors sense a light amount to determine a tilt angle of the tilt sensor. When the light amount doesn't change or when a light amount variation sensed by a second light sensor is smaller than the threshold value within a predetermined time period, a power-saving mode is performed such that the light-emitting element emits light according to a second current smaller than the first current. When the light amount variation is larger than the specific value during the power-saving mode, the working mode is performed.

Abstract: A tilt sensor with power-saving mechanism is provided. The tilt sensor includes a light-emitting element, a blocking object displaceable in an accommodating space on a baseboard, at least two first light sensors, a second light sensor and a control module. The first and the second light sensors respectively sense a light amount and a light amount variation according to the relative position of the light-emitting element and the blocking object. During a power-saving mode, when the light amount variation is larger than a specific value, the control module makes the light-emitting element work in a working mode to emit light according to a first current. During the work mode, when the light amount does not change or the light amount variation is smaller than a threshold value, the control module makes the light-emitting element work in the power-saving mode to emit light according to a second current.

Abstract: A generalized discriminative training framework for reconciling the training and evaluation objectives for document similarity is provided. Prior information about document relations and non-relations, are used to discriminatively train an ensemble of document similarity classification models. This result is a model set that can be used to compute similarity between seen documents in the training sets and new documents. The measure of similarity forms the basis of recommending documents to a user as well as being able to obtain metadata information such as keywords and tags for new documents not having such information.

Abstract: A method for indicating storage capacity is applied in a storage device. The storage device includes a main storage unit, a capacity indicator, a driver, and a secondary storage unit. The second storage unit stores a preset storage capacity value and a drive table recording relationship between storage capacity difference ranges and rotation angles of the driver. The method includes: periodically obtaining a storage capacity value from a computer connected to the storage device; computing a difference between the obtained storage capacity value and the preset storage capacity value; determining the storage capacity difference range the difference falls within and the rotation angle the determined storage capacity difference range corresponds to in the drive table; and controlling the driver to rotate the determined rotation angle to drive the capacity indicator to indicate the obtained storage capacity value. A related storage device is also provided.

Abstract: An optical sensing device includes a shell, at least one light emitting member, a rotating type shading assembly and at least one optical sensing member. The shell is formed with a black-body condition space having a light emitting chamber, a shading chamber and at least one optical sensing chamber. The light emitting member projects a light beam. The rotating type shading assembly includes a pivot and a shading member. The shading member is pivotally connected to the pivot in the shading chamber, and has a weight center offset from the pivot center. When the optical sensing device is tilted, the shading member is rotated to make the weight center located in a lowering azimuth with respect to the pivot. The optical sensing member is arranged in the optical sensing chamber, and senses the light beam to accordingly send out a sensing signal.

Abstract: A holding assembly for a seat of a bicycle has a securing base and an engaging block. The securing base has a connecting segment, an engaging segment, a securing hole and a securing bolt. The connecting segment has a connecting device connected with the seat of the bicycle. The engaging segment is formed on and protrudes from the bottom of the connecting segment and has an engaging recess having an inclined top surface. The securing bolt is slidably and rotatably mounted in the securing hole, extends into the engaging recess and has a threaded portion. The engaging block is moveably mounted in the engaging recess and has an inclined top surface abutting with the inclined top surface of the engaging recess and a threaded portion engaging the threaded portion on the securing bolt.

Abstract: An optical sensing device, which includes a shell, at least one light emitting member, a shading member, at least one anti-static member and at least one optical sensing member, is disclosed. The shell is formed with a black-body condition space therein, and the black-body condition space has a light emitting chamber, a shading chamber and at least one optical sensing chamber. The light emitting member projects a light beam into the light emitting chamber. The shading member is movably restrained within the shading chamber, and generates a static electricity when moving therein. The anti-static member is arranged in the shading chamber to ground the static electricity. The optical sensing member is arranged in the optical sensing chamber, and senses the light beam to accordingly send out a sensing signal.

Abstract: An optical sensing device includes a shell, at least one light emitting member, a rotator type shading member and at least one optical sensing member. The shell is formed with a black-body condition space having a light emitting chamber, a shading chamber and at least one optical sensing chamber. The light emitting member projects a light beam. The rotator type shading member is rotatably restrained within the shading chamber, and has a geometric center and a weight center offset from the geometric center. When the optical sensing device is lifted in a lifting azimuth or lowered in a lowering azimuth, the rotator type shading member is rotated by the geometric center to make the weight center located in the lowering azimuth with respect to the geometric center. The optical sensing member is arranged in the optical sensing chamber, and senses the light beam to accordingly send out a sensing signal.

Abstract: A method for inter-network communication between a first and second user. The method includes receiving a first request for a location associated with the second user from a first switching system for a first network in response to a second request. The method processes information associated with the first request and determines a network identifier for a second network related to the location associated with the second user, and sends the first switching system a location message, including the network identifier for the second network. The method includes receiving a third request for routing information associated with the second user from a second switching system for the second network. The method determines a location directory in the second network for the second user and receives the roaming information for the second user from the location directory. The method then sends the roaming information to the second switching system.

Abstract: A chip testing circuit is disclosed. The chip testing circuit uses a judging circuit to switch the connection of the data compressing circuit between data compressing base units which compresses 4 XIOs, so as to obtain testing data by one single interface circuit and to increase the testing throughput.

Abstract: This invention relates to a mobile electronic device and a power management method of a battery module thereof. The mobile electronic device includes a battery module, a charging/discharging module, and a control module. The charging/discharging module is coupled with the battery module. The control module is coupled with the battery module and the charging/discharging module. When the power supply is coupled with the mobile electronic device and the system time is not within a maintenance period, the control module controls the charging/discharging module to maintain capacity of the battery module within a first capacity range. When the power supply is coupled with the mobile electronic device and the system time is within the maintenance period, the control module controls the charging/discharging module to maintain the capacity of the battery module within a second capacity range.

Abstract: A process for preparing polyoxymethylene dimethyl ethers from methanol is disclosed. For example, the process comprises contacting methanol with at least one oxidant in the presence of at least one catalyst wherein the at least one catalyst comprises at least one Group VIB metal component, such as in an amount of from about 0.5 to about 50 wt % (in terms of metal oxide) and at least one Group VIII metal component, such as in an amount of from about 0.2 to about 20 wt % (in terms of metal oxide), and at least one molecular sieve having acidic catalytic activity, such as in an amount of from about 40 to about 95 wt %, based on the total weight of the at least one catalyst for a time sufficient to obtain polyoxymethylene dimethyl ethers.

Abstract: A seat tube of a bicycle has a tubular body and a tightening block. The tubular body has an insertion hole and a stationary block. The insertion hole is defined in the tubular body and has an inner surface and a tightening recess. The inner surface is formed in the tubular body. The tightening recess is defined in the inner surface. The stationary block is embedded in the tightening recess and has an oblique surface and a fastener hole. The fastener hole is defined in the oblique surface. The tightening block is mounted slidably on the oblique surface and has a tightening surface, a through hole and a fastener. The tightening surface is shaped to correspond to the inner surface. The through hole is defined through the tightening block. The fastener is mounted through the through hole and engages the fastener hole.

Abstract: A PWM comprises a voltage transformation module, a voltage-sensing module and a timer. The voltage transformation module is configured to transform an input voltage into an output voltage. The voltage-sensing module is coupled to the voltage transformation module and configured to detect a voltage of a first terminal, wherein the voltage of the first terminal is proportional to the output voltage. The timer is configured to measure the time duration for which the voltage of the first terminal is lower than a reference voltage, wherein the timer initiates a short circuit signal when the time duration is greater than a predetermined value.

Abstract: An audio jack connector includes an insulative housing (1) having a main body (10) defining a pair of opposite front and rear faces (11, 12) and a pair of opposite first and second side walls (15, 16), a set of columned mating portions (17) extending forwardly on the front face, and a set of receiving chambers (111) extending in the main body and passing through the mating portions for insertion of plugs (200); and a plurality of contacts (3) retained in the first side wall and arranged in several different rows along a transverse direction so as to protrude into the receiving chambers respectively, each row of the contacts being arranged along a front-to-back direction in accordance with an insertion direction of the plug and perpendicular to the transverse direction.

Abstract: A computer-implemented method of indexing a speech lattice for search of audio corresponding to the speech lattice is provided. The method includes identifying at least two speech recognition hypotheses for a word which have time ranges satisfying a criteria. The method further includes merging the at least two speech recognition hypotheses to generate a merged speech recognition hypothesis for the word.

Abstract: Described is a technology that provides highly accurate speech-recognized text transcripts of conversations, particularly telephone or meeting conversations. Speech is received for recognition when it is at a high quality and separate for each user, that is, independent of any transmission. Moreover, because the speech is received separately, a personalized recognition model adapted to each user's voice and vocabulary may be used. The separately recognized text is then merged into a transcript of the communication. The transcript may be labeled with the identity of each user that spoke the corresponding speech. The output of the transcript may be dynamic as the conversation takes place, or may occur later, such as contingent upon each user agreeing to release his or her text. The transcript may be incorporated into the text or data of another program, such as to insert it as a thread in a larger email conversation or the like.