Abstract: Provided are an O-succinyl homoserine transferase variant, a polynucleotide encoding the variant, a microorganism comprising the variant, and a method of producing O-succinyl homoserine using the microorganism.

Abstract: A system receives operations data and determines operations indicator(s) from the operations data. An operator on a manufacturing line reports a downtime event via a human machine interface device. The system receives downtime event and uptime information. The system calculates an operations indicator, such as an overall equipment effectiveness indicator, from the downtime event and uptime information. A user interface of the system includes the operations indicator(s) and visualizations. Some visualizations include a timeline indicating downtime events and other operations events. Additional downtime and uptime information is received by the system in substantially real-time. The system dynamically calculates updated operations indicator(s) from the additional downtime and uptime information.

Abstract: A diaper includes a diaper body and a wet diaper monitoring device, which includes a disposable pouch and a monitoring device. The monitoring device includes a monitoring casing, a first sensor electrode, a second sensor electrode, a sensing circuitry and an indicator. The first sensor electrode and the second sensor electrode are provided on an inner surface of and received in the monitoring casing, and form a single planar capacitor when the diaper body is dry. When the diaper body becomes wet, a capacitance between the first sensor electrode and the second sensor electrode increases substantially so as to transform the single planar capacitor of the first sensor electrode and the second sensor electrode into two much larger series connected capacitors.

Abstract: This document relates to materials and methods for controlling ligand gated ion channel (LGIC) activity. For example, modified LGICs including at least one LGIC subunit having a modified ligand binding domain (LBD) and/or a modified ion pore domain (IPD) are provided. Also provided are exogenous LGIC ligands that can bind to and activate the modified LGIC, as well as methods of modulating ion transport across the membrane of a cell of a mammal, methods of modulating the excitability of a cell in a mammal, and methods of treating a mammal having a channelopathy.

Abstract: A charging and drying station includes a main casing having a receiving cavity, a drying arrangement and a charger accommodation arrangement. The charger accommodation arrangement includes a utility platform securely mounted on the main casing. The utility platform has a through charger accommodating slot, wherein the charger accommodating slot is shaped and sized to fittedly accommodate at least the charging terminal of the hearing aid charger when the hearing aid charger is detachably accommodated in the receiving cavity, so that the hearing aid device is capable of being disposed on the utility platform for being simultaneously recharged and dried by the hearing aid charger and the drying arrangement respectively.

Abstract: Foldable electrical vehicles and related charging infrastructure are described. The foldable electrical vehicle generally includes three structural members (front and rear wheel-bearing structural members and a seat-bearing structural member) that are pivotally interconnected along their lengths such that they may be pivoted between a closed position wherein the three structural members are disposed roughly parallel to each other in a compact folded configuration, and an open riding configuration wherein an angular relation is formed between the structural members.

Abstract: A display mounting system including a support column, a moving bracket, an arm assembly, and a tilt assembly is described. The display mounting system includes one or more display attachment brackets to support one or more electronic displays. The display mounting system is used to hold one or more electronic displays over a worksurface or in front of a wall, and it allows the user of the display mounting system to easily change the orientation of one or more electronic displays according to user's preferences.

Abstract: The present disclosure relates to a microorganism producing L-lysine and a method for producing L-lysine by using the same. More specifically, the present disclosure relates to a microorganism of the genus Corynebacterium, which is modified such that the activity of a protein involved in cell wall hydrolysis is inactivated in comparison with the endogenous activity thereof; and a method for producing L-lysine using the same.

Abstract: The present innovation is an innovative process for the manufacturing of jewelry or jewels with silver or gold adornments, such as bracelets, necklaces, earrings, pendants, among other artifacts, from the re-utilization of strings of tennis rackets disposed of by players, forming a polymer mass that is treated to generate the pieces, such as beads, which make up the final artifact.

Abstract: A display mounting system including a support column, a moving bracket, an arm assembly, and a tilt assembly is described. The display mounting system includes one or more display attachment brackets to support one or more electronic displays. The display mounting system is used to hold one or more electronic displays over a work surface or in front of a wall, and it allows the user of the display mounting system to easily change the orientation of one or more electronic displays according to user's preferences.

Abstract: This document relates to materials and methods for controlling ligand gated ion channel (LGIC) activity. For example, modified LGICs including at least one LGIC subunit having a modified ligand binding domain (LBD) and/or a modified ion pore domain (IPD) are provided. Also provided are exogenous LGIC ligands that can bind to and activate the modified LGIC, as well as methods of modulating ion transport across the membrane of a cell of a mammal, methods of modulating the excitability of a cell in a mammal, and methods of treating a mammal having a channelopathy.

Abstract: Described herein are devices, systems, and methods to facilitate cryopreservation of a cell or a mass of a plurality of cells such as oocytes or embryos. A device of the disclosure can, for example, store oocytes or embryos during the vitrification and/or warming processes of in vitro fertilization.

Abstract: This document relates to materials and methods for modulating ligand gated ion channel (LGIC) activity. For example, modified LGICs including at least one LGIC subunit having a modified ligand binding domain (LBD) and/or a modified ion pore domain (IPD) are provided. Also provided are exogenous LGIC ligands that can bind to and activate the modified LGIC, as well as methods of modulating ion transport across the membrane of a cell of a mammal, methods of modulating the excitability of a cell in a mammal, and methods of treating a mammal having a channelopathy.

Abstract: Foldable electrical vehicles and related charging infrastructure are described. The foldable electrical vehicle generally includes three structural members (front and rear wheel-bearing structural members and a seat-bearing structural member) that are pivotally interconnected along their lengths such that they may be pivoted between a closed position wherein the three structural members are disposed roughly parallel to each other in a compact folded configuration, and an open riding configuration wherein an angular relation is formed between the structural members.

Abstract: The present disclosure relates to an O-succinyl homoserine transferase mutant, a polynucleotide encoding the same, a microorganism including the mutant, and a method of producing O-succinyl homoserine using the microorganism.

Abstract: This document relates to materials and methods for controlling ligand gated ion channel (LGIC) activity. For example, modified LGICs including at least one LGIC subunit having a modified ligand binding domain (LBD) and/or a modified ion pore domain (IPD) are provided. Also provided are exogenous LGIC ligands that can bind to and activate the modified LGIC, as well as methods of modulating ion transport across the membrane of a cell of a mammal, methods of modulating the excitability of a cell in a mammal, and methods of treating a mammal having a channelopathy.

Abstract: The present disclosure provides methods and compositions for determining whether a patient exhibiting acute gastroenteritis will benefit from treatment with therapeutic agents that inhibit Norovirus genogroup I (GI) or Norovirus genogroup II (GII). The methods disclosed herein are based on detecting Norovirus genogroup I (GI) and Norovirus genogroup II (GII) in a stool sample without extracting viral nucleic acids from a clinical specimen prior to performing real-time reverse transcription PCR. Kits for use in practicing the methods are also provided.

Abstract: This document relates to materials and methods for modulating ligand gated ion channel (LGIC) activity. For example, modified LGICs including at least one LGIC subunit having a modified ligand binding domain (LBD) and/or a modified ion pore domain (IPD) are provided. Also provided are exogenous LGIC ligands that can bind to and activate the modified LGIC, as well as methods of modulating ion transport across the membrane of a cell of a mammal, methods of modulating the excitability of a cell in a mammal, and methods of treating a mammal having a channelopathy.

Abstract: A method of assembling an adjustable fluid-filled lens assembly comprising biaxially tensioning an elastomeric membrane to a surface tension of greater than 180 N/m, typically greater than 1000 N/m; thermally conditioning the tensioned membrane, e.g., for one hour at a temperature of about 80° C., to accelerate relaxation of the membrane; mounting the membrane to a peripheral support structure whilst maintaining the tension in the membrane; assembling the mounted membrane with one or more other components to form an enclosure with the membrane forming one wall of the enclosure; and thereafter filling the enclosure with a fluid. The membrane may be formed from an aromatic polyurethane, and the fluid may be a phenylated siloxane. In some embodiments, the membrane is able to hold a substantially constant surface tension of at least 180 N/m for a period of at least 12 months.

Abstract: A universal charging and drying station includes a main unit and a hearing aid charger. The main unit includes a main casing, a lid, a hearing aid dryer, and a control circuitry. The hearing aid charging includes at least one interchangeable adapter unit, which includes a receptacle connector, a charging adapter and a connecting module. The connecting module has an adapter terminal electrically connecting to the hearing aid, and a plurality of connecting members detachably connected to the receptacle connector of the main casing. The interchangeable adapter unit may be operated between a charging mode and an interchangeable mode, wherein in the charging mode, the connecting module is electrically connected to the receptacle connector through the connecting members for charging the hearing aid, wherein in the interchangeable mode, the connecting module is detached from the receptacle connector for interchange of the interchangeable adapter unit.