Abstract: Methods of packaging a semiconductor light emitting device in a reflector having a moat positioned between a lower and an upper sidewall thereof, the upper and lower sidewall defining a reflective cavity, include dispensing encapsulant material into the reflective cavity including the light emitting device therein to cover the light emitting device and to form a convex meniscus of encapsulant material in the reflective cavity extending from an edge of the moat without contacting the upper sidewall of the reflector. The encapsulant material in the reflective cavity is cured. Packaged semiconductor light emitting devices and reflectors for the same are also provided.

Abstract: We describe a method to manipulate the phenotype of stem cells, preferably embryonic stem cells (ES), including nucleic acids and vectors used in said methods.

Abstract: We describe a method to manipulate the phenotype of stem cells, preferably pluripotential stem cells including nucleic acids and vectors used in said methods.

Abstract: Semiconductor light emitting devices, such as light emitting diodes, include a substrate, an epitaxial region on the substrate that includes a light emitting region such as a light emitting diode region, and a multilayer conductive stack including a reflector layer, on the epitaxial region. A barrier layer is provided on the reflector layer and extending on a sidewall of the reflector layer. The multilayer conductive stack can also include an ohmic layer between the reflector and the epitaxial region. The barrier layer further extends on a sidewall of the ohmic layer. The barrier layer can also extend onto the epitaxial region outside the multilayer conductive stack. The barrier layer can be fabricated as a series of alternating first and second sublayers.

Abstract: An aperture stop device is provided for use in a microscope with at least one adjustable observation parameter. The aperture stop device includes at least one aperture stop (50a, 50b) with an adjustable aperture, that is to say with an adjustable stop opening. The aperture stop (50a, 50b) is adapted to receive an aperture signal representative of an aperture to be adjusted. In addition the aperture stop device includes a control unit (52) for output of the aperture signal to the aperture stop (50a, 50b) in dependence at least on the respectively set value of the observation parameter of the microscope.

Abstract: An improved chuck with lift pins within a probe station.

Abstract: A method facilitates assembling a gas turbine engine. The method comprises providing a rotor assembly including a rotor shaft and a rotor disk that includes a radially outer rim, a radially inner hub, and an integral web extending therebetween, wherein the rotor assembly is rotatable about an axis of rotation extending through the rotor shaft, and coupling a disk retainer including at least one discharge tube to the rotor disk wherein the discharge tube extends outwardly from the disk retainer for pumping the air to a higher pressure before discharging cooling fluid therefrom in a direction that is substantially perpendicular with respect to the axis of rotation.

Abstract: A method for forming semiconductor devices using a semiconductor substrate having first and second opposed surfaces and including first and second device regions includes directing a beam of laser light at the substrate such that the beam of laser light is focused within the substrate between the first and second surfaces thereof and the beam of laser light forms a thermally weakened zone (TWZ) in the substrate. The TWZ extends between the first and second device regions and defines a break line.

Abstract: A positive working printing form precursor comprises a thermally imagable composition which includes a hydroxyl group-containing polymer, for example a novolak resin. The composition has a weight of less than 1.1 gm?2. It has been found that using a low weight of the composition on the precursor improves the properties of the precursor, in particular by rendering the sensitivity of the precursor to imaging radiation less variable over time.

Abstract: A submount for a semiconductor light emitting device includes a semiconductor substrate having a cavity therein configured to receive the light emitting device. A first bond pad is positioned in the cavity to couple to a first node of a light emitting device received in the cavity. A second bond pad is positioned in the cavity to couple to a second node of a light emitting device positioned therein. Light emitting devices including a solid wavelength conversion member and methods for forming the same are also provided.

Abstract: Broad spectrum light emitting devices and methods and semiconductor chips for fabricating such devices include a light emitting element, such as a diode or laser, which emits light in a predefined range of frequencies. The light emitting element includes a shaped substrate suitable for light extraction through the substrate and a cavity in the substrate proximate the light emitting element. For example, a trench adjacent at least a portion of the periphery of the light emitting element may be provided. The cavity/trench is configured to contain light conversion material such that light extracted from sidewalls of the cavity/trench passes through the light conversion material contained in the cavity/trench. Methods of fabricating such devices and/or chips are also provided.

Abstract: A process for the formation of a thread form in a substantially elongate member (1), wherein the thread form includes at least one rib (3) spaced apart from at least one other rib along the elongate member and wherein the thread form has a relatively coarse rib spacing but a fine thread pitch.

Abstract: A system is provided for comparing an input query with a number of stored annotations to identify information to be retrieved from a database. The comparison technique divides the input query into a number of fixed-size fragments and identifies how many times each of the fragments occurs within each annotation using a dynamic programming matching technique. The frequencies of occurrence of the fragments in both the query and the annotation are then compared to provide a measure of the similarity between the query and the annotation. The information to be retrieved is then determined from the similarity measures obtained for all the annotations.

Abstract: An indexing apparatus and method are described for use in identifying portions of data in a database for comparison with a query. In an embodiment, the index includes a key which comprises a sequence of phoneme classifications derived from the input query by classifying each of the phonemes in the input query with a number of phoneme classes, with the phonemes in each class being defined as those that are confusable with the other phonemes in the same class.

Abstract: A pump assembly and estimation and control system therefor, the pump adapted for continuous flow pumping of blood. In a particular form, the pump is a centrifugal pump wherein the impeller is entirely sealed within the pump housing and is exclusively hydrodynamically suspended therein against movement in three translational and two rotational degrees of freedom as the impeller rotates within the fluid urged by electromagnetic means external to the pump cavity. Hydrodynamic suspension is assisted by the impeller having deformities therein such as blades with surfaces tapered from the leading edges to the trailing edges of bottom and top surfaces thereof.

Abstract: Light emitting device die having a mesa configuration on a substrate and an electrode on the mesa are attached to a submount in a flip-chip configuration by forming predefined pattern of conductive die attach material on at least one of the electrode and the submount and mounting the light emitting device die to the submount. The predefined pattern of conductive die attach material is selected so as to prevent the conductive die attach material from contacting regions of having opposite conductivity types when the light emitting device die is mounted to the submount. The predefined pattern of conductive die attach material may provide a volume of die attach material that is less than a volume defined by an area of the electrode and a distance between the electrode and the submount. Light emitting device dies having predefined patterns of conductive die attach material are also provided.

Abstract: Light emitting diodes include a substrate, an epitaxial region on the substrate that includes therein a diode region and a multilayer conductive stack on the epitaxial region opposite the substrate. A passivation layer extends at least partially on the multilayer conductive stack opposite the epitaxial region, to define a bonding region on the multilayer conductive stack opposite the epitaxial region. The passivation layer also extends across the multilayer conductive stack, across the epitaxial region and onto the substrate. The multilayer conductive stack can include an ohmic layer on the epitaxial region opposite the substrate, a reflector layer on the ohmic layer opposite the epitaxial region and a tin barrier layer on the reflector layer opposite the ohmic layer. An adhesion layer also may be provided on the tin barrier layer opposite the reflector layer. A bonding layer also may be provided on the adhesion layer opposite the tin barrier layer.

Abstract: The functionality of a blade is expanded by the installation of an expansion unit including expansion components. The blade and expansion unit are provided with connectors allowing the blade components to access and utilize the expansion components when the connectors are mated. The blade and expansion unit include elements ensuring that the connectors align properly as the expansion unit is installed onto the blade, making the installation simple and quick. The blade and expansion unit also include elements securing the connection between the two, once made.

Abstract: The construction of transgenic animal models of human Alzheimer'disease, and methods of using the models to screen potential Alzheimer's disease therapeutics, are described. The models are characterized by pathologies similar to pathologies observed in Alzheimer's disease, based on expression of all three forms of the &bgr;-amyloid precursor protein (APP), APP695, APP751, and APP770, as well as various point mutations based on naturally occurring mutations, such as the London and Indiana familial Alzheimer's disease (FAD) mutations at amino acid 717, predicted mutations in the APP gene, and truncated forms of APP that contain the A&bgr; region. Animal cells can be isolated from the transgenic animals or prepared using the same constructs with standard techniques such as lipofection or electroporation.

Abstract: A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base.