Patents by Inventor Peter Becker

Peter Becker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12252685
    Abstract: A feed control system and related methods for a heterologous product, such as a human milk oligosaccharide, fermentation system are disclosed. The feed control system comprises a feed controller. The feed controller comprises a processor and an interface. The processor is configured to obtain a biomass content in a fermentation broth. The processor is configured to determine a carbon input parameter based on the biomass content. The processor is configured to control a carbon input to the fermentation broth according to the carbon input parameter.
    Type: Grant
    Filed: November 10, 2022
    Date of Patent: March 18, 2025
    Assignee: DSM IP ASSETS B.V.
    Inventors: Natalia Chrapkova, Peter Becker, Ted Johanson, Mikael Jansen
  • Publication number: 20240409972
    Abstract: The present disclosure relates to the production of oligosaccharides, especially Human milk Oligosaccharides (HMOs) using a genetically engineered cell which has decreased or total loss of function of phosphoglycerol transferase I and II and/or phosphoethanolamine transferase and/or glucans biosynthesis protein C to reduce oligosaccharide by-products and/or increase oligosaccharide production.
    Type: Application
    Filed: June 6, 2024
    Publication date: December 12, 2024
    Inventors: Peter BECKER, Manos PAPADAKIS
  • Publication number: 20240327885
    Abstract: The present disclosure relates to a method for the production of a human milk oligosaccharide (HMO) blend with LNFP-I and 2?-FL as the predominant HMO's, the method comprising the steps of providing a genetically engineered cell, which comprises a heterologous ?-1,3-N-acetyl-glucosaminyltransferase protein, a heterologous ?-1,3-galactosyltransferase protein, a heterologous ?-1,2-fucosyltransferase protein, and expresses functionally the colanic acid gene cluster, comprises a native or heterologous regulatory or episomal element for controlling the expression of the proteins and optionally express a heterologous sugar transporter, and culturing the cell in a suitable cell culture medium to express said proteins and to produce an HMO blend.
    Type: Application
    Filed: May 17, 2022
    Publication date: October 3, 2024
    Inventors: Manos PAPADAKIS, Ted JOHANSON, Peter BECKER
  • Publication number: 20240327886
    Abstract: This invention relates to a method of producing mixtures of various human milk oligosaccharides (HMOs) with unique HMO blend profiles, consisting predominantly of LNFP-I and LNT and of other HMOs in less significant amounts. The less abundant HMOs might be 2?-FL, LNT-II or DFL. The strategies for achieving specific HMO blends include strain engineering and fermentation methods.
    Type: Application
    Filed: May 17, 2022
    Publication date: October 3, 2024
    Inventors: Manos PAPADAKIS, Ted JOHANSON, Peter BECKER
  • Publication number: 20240327777
    Abstract: A feed control system and related methods for a heterologous product, such as a human milk oligosaccharide, fermentation system are disclosed. The feed control system comprises a feed controller. The feed controller comprises a processor and an interface. The processor is configured to obtain a biomass content in a fermentation broth. The processor is configured to determine a carbon input parameter based on the biomass content. The processor is configured to control a carbon input to the fermentation broth according to the carbon input parameter.
    Type: Application
    Filed: November 10, 2022
    Publication date: October 3, 2024
    Inventors: Natalia CHRAPKOVA, Peter BECKER, Ted JOHANSON, Mikael JANSEN
  • Patent number: 11926858
    Abstract: The invention relates to a genetically modified microorganism for making a oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source.
    Type: Grant
    Filed: April 4, 2022
    Date of Patent: March 12, 2024
    Assignee: GLYCOM A/S
    Inventors: Margit Pedersen, Manos Papadakis, Peter Becker, Eric Samain, Pauline Peltier-Pain, Katrine Bych, Ted Johanson, Elise Champion, Gyula Dekany
  • Publication number: 20230016623
    Abstract: Herein is reported a method for determining methylation of a promoter nucleic acid operably linked to a nucleic acid encoding a polypeptide and thereby determining the long-term productivity of a cell. Also an aspect is a method for selecting a cell for producing a polypeptide by determining the methylation of the promoter nucleic acid operably linked to the structural gene encoding the polypeptide.
    Type: Application
    Filed: April 15, 2022
    Publication date: January 19, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Ulrich Goepfert, Peter Becker, Benjamin Moritz
  • Publication number: 20220235388
    Abstract: The invention relates to a genetically modified microorganism for making a oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source.
    Type: Application
    Filed: April 4, 2022
    Publication date: July 28, 2022
    Inventors: Margit Pedersen, Manos Papadakis, Peter Becker, Eric Samain, Pauline Peltier-Pain, Katrine Bych, Ted Johanson, Elise Champion, Gyula Dekany
  • Patent number: 11332797
    Abstract: Herein is reported a method for determining methylation of a promoter nucleic acid operably linked to a nucleic acid encoding a polypeptide and thereby determining the long-term productivity of a cell. Also an aspect is a method for selecting a cell for producing a polypeptide by determining the methylation of the promoter nucleic acid operably linked to the structural gene encoding the polypeptide.
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: May 17, 2022
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ulrich Goepfert, Peter Becker, Benjamin Moritz
  • Patent number: 11293042
    Abstract: The invention relates to a genetically modified microorganism for making a oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: April 5, 2022
    Assignee: GLYCOM A/S
    Inventors: Margit Pedersen, Manos Papadakis, Peter Becker, Eric Samain, Pauline Peltier-Pain, Katrine Bych, Ted Johanson, Elise Champion, Gyula Dekany
  • Patent number: 11234411
    Abstract: An odor eliminating pet bed assembly for absorbing odors associated with pet beds includes a pet bed that is positionable on a support surface for to have a pet lie thereon. The pet bed has a chamber is integrated therein for receiving an odor absorbing material. A permeable cushion is positioned within the pet bed to have the pet lie thereon when the pet is in the pet bed. The permeable cushion passes the odor absorbing material therethrough. An impermeable cushion is positioned within the pet bed to have the pet lie thereon. The impermeable cushion is comprised of a fluid impermeable material to inhibit the odor absorbing material from passing therethrough.
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: February 1, 2022
    Inventor: Peter Becker
  • Publication number: 20210243996
    Abstract: An odor eliminating pet bed assembly for absorbing odors associated with pet beds includes a pet bed that is positionable on a support surface for to have a pet lie thereon. The pet bed has a chamber is integrated therein for receiving an odor absorbing material. A permeable cushion is positioned within the pet bed to have the pet lie thereon when the pet is in the pet bed. The permeable cushion passes the odor absorbing material therethrough. An impermeable cushion is positioned within the pet bed to have the pet lie thereon. The impermeable cushion is comprised of a fluid impermeable material to inhibit the odor absorbing material from passing therethrough.
    Type: Application
    Filed: February 11, 2020
    Publication date: August 12, 2021
    Inventor: Peter Becker
  • Patent number: 11007925
    Abstract: An assistance method for a light control system in a motor vehicle, having a light controller for controlling a lighting unit in the motor vehicle for lighting a motor vehicle environment, a portable unit, at least one communication interface, and an evaluation unit for evaluating signals from the portable unit received via the communication interface. The lighting unit being controllable by the light controller and in accordance with the evaluation of the signals received from the portable unit in a first assistance function, such that at least one light beam emitted by the lighting unit can be positioned as a function of the position of the portable unit. The lighting unit is controlled via the light controller, such that when the first assistance function is switched on, the light beam emitted by the lighting unit automatically tracks the portable unit in accordance with the motion trajectory of the portable unit.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: May 18, 2021
    Assignee: Hella GmbH & Co. KGaA
    Inventors: Ludger Weghaus, Lars-Peter Becker
  • Publication number: 20200354761
    Abstract: The invention relates to a genetically modified microorganism for making a oligosaccharide, preferably of 3-8 monosaccharide units, more preferably of 3-5 monosaccharide units, particularly a HMO, which comprises one or more genes encoding a sucrose utilization system, so the microorganism can use sucrose as a carbon and energy source.
    Type: Application
    Filed: July 13, 2020
    Publication date: November 12, 2020
    Inventors: Margit Pedersen, Manos Papadakis, Peter Becker, Eric Samain, Pauline Peltier-Pain, Katrine Bych, Ted Johanson, Elise Champion, Gyula Dekany
  • Publication number: 20200291064
    Abstract: The present invention is directed to methods for the separation of a molecule of interest from a solution containing the molecule using dual stage tangential-flow ultrafiltration (“TFF”). In particular, the methods of the invention are directed to the processing of crude feed streams such as conditioned cell culture supernatant to dramatically reduce contaminant and/or impurity levels prior to subsequent, i.e., downstream, refining unit operations. The methods of the invention may be used in the processing of a crude feed stream from biological production systems such as fermentation or other cell culture process, and may further eliminate the need for time consuming impurity precipitation (e.g., pH driven) and/or precipitate filtration processes prior to downstream processes that are sensitive to high impurity loads such as chromatographic unit operations.
    Type: Application
    Filed: February 21, 2020
    Publication date: September 17, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Peter Becker, Sebastian Neumann
  • Publication number: 20200079276
    Abstract: An assistance method for a light control system in a motor vehicle, having a light controller for controlling a lighting unit in the motor vehicle for lighting a motor vehicle environment, a portable unit, at least one communication interface, and an evaluation unit for evaluating signals from the portable unit received via the communication interface. The lighting unit being controllable by the light controller and in accordance with the evaluation of the signals received from the portable unit in a first assistance function, such that at least one light beam emitted by the lighting unit can be positioned as a function of the position of the portable unit. The lighting unit is controlled via the light controller, such that when the first assistance function is switched on, the light beam emitted by the lighting unit automatically tracks the portable unit in accordance with the motion trajectory of the portable unit.
    Type: Application
    Filed: November 12, 2019
    Publication date: March 12, 2020
    Applicant: Hella GmbH & Co. KGaA
    Inventors: Ludger WEGHAUS, Lars-Peter BECKER
  • Publication number: 20200079277
    Abstract: An assistance method for a light control system in a motor vehicle, having a light controller for controlling a lighting unit in the motor vehicle for lighting a motor vehicle environment, a portable unit, at least one communication interface, and an evaluation unit for evaluating signals from the portable unit received via the communication interface. The lighting unit being controllable by the light controller and based on evaluation of the signals received from the portable unit, such that at least one light beam emitted by the lighting unit can be positioned in accordance with signals from the portable unit. A first assistance function manually or automatically switches on, the lighting unit is controlled such that when the first assistance function is switched on, the light beam moves automatically as a function of the portable unit being actuated at a time that follows the switching on of the first assistance function.
    Type: Application
    Filed: November 12, 2019
    Publication date: March 12, 2020
    Applicant: HELLA GmbH & Co. KGaA
    Inventors: Ludger WEGHAUS, Lars-Peter BECKER
  • Patent number: 9851209
    Abstract: Systems, methods, and computing devices for building, operating and using map systems with signature-based map caches are disclosed. Based on the desired map properties included in a formatted map request, a map signature can be generated. The map signature can be used to access a signature based map cache to determine whether a map with identical map properties has been previously generated and stored in cache or otherwise available for retrieval. If the map signature exists in the map cache, the corresponding map can be delivered to a map client. If the map signature does not exist in the map cache, then a map can be generated or rendered based on the map properties in the map request. Once the map is generated, it can be saved to the map cache along with associated map signature for future retrieval.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: December 26, 2017
    Assignee: ENVIRONMENTAL SYSTEMS RESEARCH INSTITUTE, INC.
    Inventor: Peter Becker
  • Patent number: 9819964
    Abstract: Embodiments of the invention relate to an image or raster compression method for a multi-dimensional array of pixels. A user specifies a maximum error allowable per pixel for the compression algorithm. The raster is divided into a number of pixel blocks where each pixel is quantized and bit stuffed based on a number of block statistics including the maximum error allowable. The size of the pixel blocks is limited to two (e.g., 8×8 and 16×16) to save processing time with little difference in compression. A Look-Up Table (LUT) is used instead for certain types of data where it is more efficient.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: November 14, 2017
    Assignee: ENVIRONMENTAL SYSTEMS RESEARCH INSTITUTE, INC.
    Inventors: Thomas Maurer, Peng Gao, Peter Becker
  • Publication number: 20170081732
    Abstract: Herein is reported a method for determining methylation of a promoter nucleic acid operably linked to a nucleic acid encoding a polypeptide and thereby determining the long-term productivity of a cell. Also an aspect is a method for selecting a cell for producing a polypeptide by determining the methylation of the promoter nucleic acid operably linked to the structural gene encoding the polypeptide.
    Type: Application
    Filed: May 13, 2015
    Publication date: March 23, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Ulrich Goepfert, Peter Becker, Benjamin Moritz