Abstract: An analysis instrument comprises plural modules connected together over a data network, each module comprising an analysis apparatus operable to perform biochemical analysis of a sample. Each module comprises a control unit that controls the operation of the analysis apparatus. The control units are addressable to select an arbitrary number of modules to operate as a cluster for performing a common biochemical analysis. The control units communicate over the data network, repeatedly during the performance of the common biochemical analysis, to determine the operation of the analysis apparatus of each module required to meet the global performance targets, on the basis of measures of performance derived from the output data produced by the modules. The arrangement of the instrument as modules interacting in this manner provides a scalable analysis instrument.

Abstract: A method for separating a parent isotope from a daughter isotope is provided, the method comprising supplying irradiated target; dissolving the irradiated target; treating the dissolved irradiated target to a precipitation step to form a first solid phase of the parent isotope and a first liquid phase of the daughter isotope; filtering the first liquid phase of daughter isotope to create a first purified fraction of the daughter isotope to create a second solid phase of the parent isotope and a second liquid phase of the daughter isotope; and filtering the second liquid phase to create a second liquid fraction of the daughter isotope. The process can be repeated until the 99Mo is exhausted and the enriched target material 98Mo or 100Mo can be easily re-used.

Abstract: When generating a stimulation signal comprising stimulation pulses delivered to a target area of a human or animal body, an electrophysiological signal measured from the body for closed-loop control of the stimulation signal, is sampled, at a sampling frequency in an analogue-to-digital converter for deriving a feedback signal for closed-loop control of the stimulation signal. The generation of the stimulation signal and the sampling of the electrophysiological signal are synchronised and have a relative phase selected to cause the sampling to occur outside the stimulation pulses, which prevents the effect of the stimulation pulses from interfering with the digital electrophysiological signal, whiles allowing maintenance of Nyquist-Shannon rules and the integrity of the discrete Laplace transform (z-transform) required in discrete control theory.

Abstract: An emulation apparatus emulates an electrophysiological signal derived from a target area of a human or animal nervous system under the influence of a stimulation signal applied to the human or animal body. A prior signal generator generates a prior signal representing an electrophysiological signal in the absence of stimulation. A test signal representing a stimulation signal is received and used by a modelling unit to derive a modulation signal representing the degree of modulation of the electrophysiological signal, in accordance with a model of the temporal evolution of the modulation of the electrophysiological signal caused by the stimulation signal. A modulation unit modulates the prior signal in accordance with the modulation signal to output an emulation signal representing an electrophysiological signal derived under the influence of the stimulation signal. The emulation apparatus has wide use in neuroscience research, bioengineering and clinical applications.

Abstract: Systems, methods, architectures, mechanisms or apparatus for streaming content toward client devices, comprising a content delivery system configured to automatically ingest content asset packages and publish identifying data associated with content assets encrypted and stored therein at a content delivery network (CDN), a virtualized Digital Rights Management (DRM) platform configured to provide content encryption keys to the content delivery system and to authorized client devices, and a virtualized services platform configured to interact with client devices to authenticate client devices, receive client device content requests, and cause the CDN to transmit requested content to an authorized client device.

Abstract: An intravascular fluid movement device that includes an expandable member having a collapsed, delivery configuration and an expanded, deployed configuration, the expandable member having a proximal end and a distal end, a rotatable member disposed radially and axially within the expandable member, and a conduit coupled to the expandable member, the conduit at least partially defining a blood flow lumen between a distal end of the conduit and a proximal end of the conduit, the conduit disposed solely radially inside of the expandable member in a distal section of the expandable member.

Abstract: There is provided a hinge including a first hinge member that is L-shaped. The hinge includes a second hinge member hingedly coupled to the first hinge member and L-shaped at least in part. There is also provided a folding table with a tabletop. The folding table includes at least one leg. The folding table includes a hinge mechanism coupled to the tabletop and the leg so as to enable the leg to move from a stored position to a deployed position. The folding table includes one or more of: i) a brace configured to support the leg in the deployed position and integrally connected to and formed with the hinge mechanism; and ii) a locking mechanism which when actuated is configured to inhibit movement of the leg from the deployed position to the stored position, with the locking mechanism being integrally connected to and formed with the hinge mechanism.

Abstract: Systems and methods provide custom synchronization procedures in file synchronization. A primary agent is used to monitor for changes, create synchronization plans to synchronized changes, and execute the synchronization plan. The primary agent, however, interacts with one or more separate custom agents to customize the synchronization plans. One exemplary technique involves monitoring for local changes to a first copy of a file tree and updates from another computing device regarding remote changes to a second copy of the file tree. When a change to either copy is identified, a synchronization plan for the change is created based on a default synchronization procedure. The synchronization plan is sent to a custom agent for customization. The custom agent creates the custom synchronization plan by modifying the synchronization plan and sends the custom synchronization plan to the primary agent. The custom synchronization plan is then executed by the primary agent.

Abstract: There is provided a stimulation device for treatment of gait impairment of a patient. The stimulation device is configured to apply respective stimulation signals to electrodes bilaterally implanted in two subcortical regions of the left and right hemispheres of the brain of the patient, the subcortical regions being associated with motor control. The stimulation device is configured to apply respective stimulation signals having a rate of electrical energy delivered that is modulated with alternating waveforms at a gait frequency and out of phase with each other.

Abstract: An intravascular fluid movement device that includes an expandable member having a collapsed, delivery configuration and an expanded, deployed configuration, the expandable member having a proximal end and a distal end, a rotatable member disposed radially and axially within the expandable member, and a conduit coupled to the expandable member, the conduit at least partially defining a blood flow lumen between a distal end of the conduit and a proximal end of the conduit, the conduit disposed solely radially inside of the expandable member in a distal section of the expandable member.

Abstract: A method is provided. The method includes determining whether second event data of a second data stream of the plurality of data streams is stored in a cache memory in accordance with a first key. The method further includes performing a join operation of the first event data and the second event data at least partially in view of whether the second event data is stored in the cache memory.

Abstract: Aluminum structures, such as tactical vehicle hulls, include plural aluminum components formed from a first alloy composition and joined by one or more welded seam(s). The welded seam(s) may be formed by friction stir welding and/or gas metal arc welding using welding wire made from the first alloy composition. In this manner, all component parts are made from the same alloy composition, providing a more homogeneous structure. The welded component parts then may be placed in a heat treatment furnace to temper the structure. Because essentially all of the aluminum structure before heat treating—the welded seam(s) and the individual component parts—is formed of the same starting material and these parts/seam(s) are simultaneously and evenly heat treated, the resultant hardened, heat-treated part (e.g., a vehicle hull) has a more homogeneous hardened/heat treated structure in the individual parts and across the welded seam(s).

Abstract: Systems and methods are described for a cross-site high availability distributed storage system. According to one embodiment, a computer implemented method includes providing a remote direct memory access (RDMA) request for a RDMA stream, and generating, with an interconnect (IC) layer of the first storage node, multiple IC channels and associated IC requests for the RDMA request. The method further includes mapping an IC channel to a group of multiple transport layer sessions to split data traffic of the IC channel into multiple packets for the group of multiple transport layer sessions using an IC transport layer of the first storage node and assigning, with the IC transport layer, a unique transaction identification (ID) to each IC request and assigning a different data offset to each packet of a transport layer session.

Abstract: Systems and methods for an interconnect layer send queue reservation system are provided. In one example, a method involves performing a transfer of data (e.g., an NVLog) from a storage system to a secondary storage system. A send queue having a fixed number of slots is maintained within an interconnect layer interposed between a file system and a Remote Direct Memory Access (RDMA) layer of the storage system. The interconnect layer implements an application programming interface (API) for the reservation system. A deadlock situation is avoided by, during a suspendable phase of a write transaction, making a reservation for slots within the send queue via the reservation system for the transfer of data. When the reservation is successful, the write transaction proceeds with a modify phase, during which the reservation is consumed and the interconnect layer is caused to perform an RDMA operation to carry out the transfer of data.

Abstract: The invention relates to a robot-mounted 3D printing apparatus for printing biocompatible materials for performing in-situ surgical repairs and comprises one UV curable reagent container and one cell supporting reagent container which are co-axially extruded from a tip and cured to perform in-situ repairs.

Abstract: A method and system are described for, based upon a plurality of previously-acquired directional LFP signals measured in a plurality of different directions at a directional sensor lead located in a predetermined region of a patient's brain, determining optimised patient-specific programming parameters for programming a directional stimulation lead with parameters for stimulating the said region. The method comprises a first step of determining, over at least one predetermined frequency range, a power-frequency variation curve of each of the directional LFP signals, a second step of identifying frequency peaks in the power-frequency variation curves, a third step of detecting one of the identified frequency peaks at which a maximum difference in signal power between the directional LFP signals occurs, and a fourth step of calculating a plurality of directional stimulation weighting factors on the basis of the relative signal powers of the directional LFP signals at the detected frequency peak.

Abstract: Adjacent tissue layers can be accessed using a catheter device with a distal tip having a conductive portion including a first cutting feature and one or more projections extending from the first cutting feature towards an outer diameter of the distal tip. Electrical energy can be supplied to the conductive portion of the device to cut tissue. A stent can be delivered to form a fluid communication between the adjacent tissue layers.

Abstract: An emulation apparatus emulates an electrophysiological signal derived from a target area of a human or animal nervous system under the influence of a stimulation signal applied to the human or animal body. A prior signal generator generates a prior signal representing an electrophysiological signal in the absence of stimulation. A test signal representing a stimulation signal is received and used by a modelling unit to derive a modulation signal representing the degree of modulation of the electrophysiological signal, in accordance with a model of the temporal evolution of the modulation of the electrophysiological signal caused by the stimulation signal. A modulation unit modulates the prior signal in accordance with the modulation signal to output an emulation signal representing an electrophysiological signal derived under the influence of the stimulation signal. The emulation apparatus has wide use in neuroscience research, bioengineering and clinical applications.

Abstract: Eyewear device includes an eyeglass frame, a temple, and a coupling device for hingedly coupling the temple to the eyeglass frame, formed of an elastically deformable material, and including a single flexible arm of an elongate shape and a front end portion positioned and retained against the front surface of the eyeglass frame. The single flexible arm extends from the front end portion into a slot in the frame and an internal elongate slot in the temple positioned in opposing alignment therewith. The elasticity of the coupling device flexibly, hingedly couples the temple to the eyeglass frame and allows a temple that has suffered inordinate bending moments and directions to instantly return to nominal use by retightening or replacing the coupling device, and/or by repositioning the temple to properly abut the eyeglass frame.