Abstract: This invention provides compounds, compositions and methods for treating a cognitive disorder or memory disorder in animals that result from aging or other neurodegenerative condition. In particular, compounds of this invention can stimulate neural cell growth, increased amounts of cells containing a key enzyme needed for production of the cholinergic neurotransmitter, and can improve memory and cognitive function in animals who have experienced a loss of memory or cognitive function.

Abstract: A fan assembly for creating an air current includes an air inlet, an air outlet, an impeller, a motor for rotating the impeller to create an air flow passing from the air inlet to the air outlet, the air outlet comprising an interior passage for receiving the air flow and a mouth for emitting the air flow, the air outlet defining an opening through which air from outside the fan assembly is drawn by the air flow emitted from the mouth, a control circuit for controlling the motor, a remote control for transmitting control signals to the control circuit, and at least one magnet for attaching the remote control to the air outlet.

Abstract: A damage sensor, for example a crack gauge, a method of providing the same, and a method of sensing damage using the same, are described. The damage sensor comprises at least one direct write resistive element applied to an area of a substrate by a direct write process. Conductive tracks may be connected along two separated portions of the perimeter of the area of the direct write resistive element. The damage sensor may comprise plural direct write resistive elements, for example rectangular-shaped elements, each extending between and connected to two conducting tracks. In a further damage sensor, plural annular resistive elements are positioned in an annular arrangement with respect to each other. In all the damage sensors, the resistive elements may be applied around a hole in a substrate, or extending over a bonded edge between two substrates.

Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.

Abstract: A bladeless fan assembly (100) for creating an air current comprises a nozzle (1) mounted on a base (16) housing for creating an air flow through the nozzle (1). The nozzle (1) comprises an interior passage (10) for receiving the air flow from the base (16) and a mouth (12) through which the air flow is emitted. The nozzle (1) extends about an axis to define an opening (2) through which air from outside the fan assembly (100) is drawn by the air flow emitted from the mouth (12). The nozzle (1) comprises a surface over which the mouth (12) is arranged to direct the air flow. The surface comprises a diffuser portion (46) tapering away from the axis, and a guide portion (48) downstream from the diffuser portion (46) and angled thereto.

Abstract: An upright surface treating appliance includes a main body having a user operable handle, and a support assembly for allowing the appliance to be rolled along a surface using the handle. The support assembly includes a yoke and a pair of wheels rotatably connected to the yoke, the yoke being shaped so that a section of the yoke lies between the rims of the wheels. A surface treating head is connected to the yoke. The main body is pivotably connected to the yoke for movement about a pivot axis passing between the wheels, and so that a part of the main body is located between the rims of the wheels. As the main body is pivoted about said axis from an upright position to a reclined position, the spacing between said section of the yoke and said part of the main body increases, and so a shield is provided for covering the gap so formed between said section of the yoke and said part of the main body to prevent dirt and dust from passing into the support assembly through the gap.

Abstract: An upright surface treating appliance includes a main body having a user operable handle, a surface treating head connected to a yoke moveable relative to the main body, a stand moveable relative to both the main body and the yoke between a supporting position for supporting the main body in an upright position, and a retracted position, and a stand retaining mechanism for releasably retaining the stand in the supporting position and from which the stand is releasable upon application of a force to one of the main body and the stand. The yoke is moveable relative to the main body in response to an impact on the surface treating head to apply said force to the stand. This allows the force of the impact on the surface treating head to be transferred through the stand to the stand retaining mechanism, which, depending on the magnitude of the impact, can release both the stand and the yoke for movement relative to the main body.

Abstract: An upright surface treating appliance includes a main body, a surface treating head connected to a yoke, and a stand. To provide a compact appliance the yoke and the stand are pivotable independently relative to the main body about a common pivot axis. This can also enable the yoke and the stand to be rotatably connected to the main body using one or more common connectors or bearings.

Abstract: An upright surface treating appliance includes a main body having a user operable handle, and a support assembly for allowing the appliance to be rolled along a surface using the handle. The support assembly includes a yoke pivotably connected to the main body, and a pair of domed-shaped wheels rotatably connected to the yoke. A surface treating head is connected to the yoke. The yoke is shaped so that a section of the yoke is located between the rims of the wheels. To afford a compact appearance to the appliance, the outer surfaces of the wheels and the section of the yoke together at least partially delimit a substantially spherical volume.

Abstract: An upright vacuum cleaning appliance includes a main body having a user operable handle, separating apparatus for separating dirt from a dirt-bearing air flow and a casing housing a fan unit for drawing the air flow through the separating apparatus. A support assembly is connected to the main body for allowing the appliance to be rolled along a surface using the handle. The support assembly includes a pair of domed-shaped wheels which each have a substantially circular rim. The overall size of the appliance is reduced by locating the casing between the wheels, and providing an air duct which extends between the rims of the wheels to convey the air flow from the separating apparatus to the casing.

Abstract: A spring-applied parking brake with manual release and reapply. A gear box fixed relative to the rear wall of a cylinder has a manual crank. A pushrod extending through the cylinder and gear box is connected to provide braking force. A threaded collet surrounding helical threads on the pushrod has flexible radially expandable tines. When the gear box is manually cranked, the pushrod is rotated and due to interaction of the threads on the inside of the collet and on the pushrod, the pushrod is moved axially releasing or reapplying the brake.

Abstract: The path selection and wavelength assignment to a selected path are performed by mapping the wavelength reach to the demand distribution (agile reach) resulting in a 50-60% increase in the network reach. The network reach is further increased (about 2.2 times) when on-line measured performance data are used for path selection and wavelength assignment. The connections may be engineered/upgraded individually, by optimizing the parameters of the entire path or of a regenerator section of the respective path. The upgrades include changing the wavelength, adjusting the parameters of the regenerator section, controlling the launch powers, mapping a certain transmitter and/or receiver to the respective wavelength, selecting the wavelengths on a certain link so as to reduce cross-talk, increasing wavelength spacing, etc.

Abstract: A domestic appliance includes a head divided into a first rotatable member and a second rotatable member, and a drive mechanism for rotating the head about a first axis while simultaneously rotating the first rotatable member about a second axis and the second rotatable member about a third axis. Each of the second axis and the third axis is angled to and preferably intersects the first axis. When viewed in a direction extending along the second axis towards the first axis, the drive mechanism rotates the first rotatable member about the second axis in a first angular direction and the second rotatable member about the third axis in a second angular direction opposite to the first angular direction.

Abstract: A hydraulic valve includes a main body, a valve body, a piston, a valve sleeve, a spool and a resilient energy storage member. The valve body and the piston are disposed within the main body. The valve body defines a first chamber, a second chamber, and a cylindrical passage connecting the first chamber and the second chamber. The valve sleeve is moveably disposed in the cylindrical passage. The spool is moveably disposed within the bore of the valve sleeve. The resilient energy storage member may be disposed between the valve sleeve and valve spool. The resilient energy storage member is compressed as pressure is induced in one of the first chamber or the second chamber such that the valve sleeve and the spool move relative to one another so that at least a portion of the shaped aperture is exposed to the first chamber or second chamber to allow a proportional amount of hydraulic fluid to flow between the first chamber and the second chamber.

Abstract: A fan assembly for creating an air current, the fan assembly having a base including a system for creating an air flow and a side wall that, at least partially encloses the system for creating the air flow and has a plurality of air inlets, wherein the plurality of air inlets allow air to enter the base, and a nozzle, mounted on the base, having an interior passage for receiving the air flow from the base, and a mouth through which the air flow is emitted from the fan assembly.

Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.

Abstract: The invention concerns RAC-PK and fragments thereof, as well as activators and inhibitors of RAC-PK for use as medicaments, particularly in the treatment of diseases concerned with abnormalities in processes modulated by insulin, such as cellular proliferation, insulin deficiency and/or excess blood sugar levels. Moreover, the invention provides RAC-PK for use in screening potential mimics or modulators thereof. A method for screening for agents capable of affecting the activity of GSK3 is also disclosed. The invention further provides a screening kit comprising the RAC-PK as an active principle, and a method for screening compounds which are candidate mimics or modulators of RAC-PK activity comprising detecting specific interactions between the candidate compounds and RAC-PK. There is also provided a process for activating RAC-PK comprising treatment thereof with a phosphatase inhibitor.

Abstract: A method for managing rights in digital content includes generating rights data for a piece of digital content and forming a piece of rights managed digital content by associating the rights data with the piece of digital content. The rights data includes parameters that govern the terms on which the content may be licensed, and may include a list of entities to which the content may be licensed, a respective set of one or more rights that each such entity has in the digital content, and any conditions that may be placed on those rights. A method for licensing rights managed digital content includes receiving a license request for a license to use the piece of rights managed digital content, where the license request includes such a signed rights label. The digital signature on the signed rights label is validated to determine whether a trusted entity issued the signed rights label.

Abstract: The present subject matter relates generally to temperature sensors using a thin film element. Various embodiments of the present subject matter include a temperature sensor assembly. The temperature sensor assembly includes an enclosure having an inside surface and a thin film element housed in the enclosure. A thermally conductive material connects a surface of the thin film element directly to the inside surface of the enclosure in a side mounted manner to provide rapid thermal conduction from the enclosure to the thin film element. In various embodiments, the thin film element is a resistance temperature detector (RTD).

Abstract: To control privileges and access to resources on a per-process basis, an administrator creates a rule that may be applied to modify a token of a process. The rule may include an application-criterion set and changes to be made to the groups and/or privileges of the token. The rule may be set as a policy within a group policy object (GPO), where a GPO is associated with one or more groups of computers or users. When a GPO containing a rule is applied to a computer, a driver installed on the computer may access the rule(s) anytime a logged-on user executes a process. If the executed process satisfies the criterion set of a rule, the changes contained within the rule are made to the process token, and the user has expanded and/or contracted access and/or privileges for only that process.