Patents by Inventor Peter David

Peter David has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic amine derivatives as inhibitors of class 1 receptor tyrosine kinases
    Publication number: 20030153755
    Abstract: Fused bicyclic amines of formula (1) are described wherein Ar is an aryl or heteroaryl group; Y is a —S(O2)— or —C(O)— group; R1 is a hydrogen or halogen atom or an alkyl, haloalkyl, alkoxy, haloalkoxy or cyano group; X is a nitrogen atom or a C(R1a) group where R1a is as defined for R1 and may be the same or different; W and Z are each a carbon atom and together with U form an optionally substituted five- or six-membered monocyclic aromatic or heteroaromatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the activity of Class I receptor tyrosine kinases and are of use in the prophylaxis and treatment of hyperproliferative disorders such as cancer, psoriasis, restenosis, atherosclerosis and fibrosis.
    Type: Application
    Filed: February 4, 2003
    Publication date: August 14, 2003
    Inventors: David Festus Charles Moffat, Peter David Davis
  • Substituted isoquinoline derivatives and their use as anticonvulsants
    Publication number: 20030144320
    Abstract: This invention relates to substituted isoquinoline derivatives and their use as anticonvulsants.
    Type: Application
    Filed: January 29, 2003
    Publication date: July 31, 2003
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Mervyn Thompson, Robert William Ward, Peter David Edwards
  • Fused polycyclic 2-aminopyrimidine derivatives
    Patent number: 6599908
    Abstract: Fused polycyclic 2-aminopyrimidines of formula (1): wherein Ar is an optionally substituted aromatic or heteroaromatic group; X is a carbon or nitrogen atom; Y is a carbon or nitrogen atom; Z is a linker group; A together with X and Y forms an optionally substituted monocyclic or bicyclic aromatic or heteroaromatic group; and the salts, solvates, hydrates and N-oxides thereof are described. The compounds are potent and selective inhibitors of the protein tyrosine kinases p56lck and p59fyn and are of use in the prophylaxis and treatment of immune diseases, hyperproliferative disorders and other diseases in which inappropriate p56lck and/or p59fyn activity is believed to have a role.
    Type: Grant
    Filed: March 2, 2000
    Date of Patent: July 29, 2003
    Assignee: Celltech R & D Limited
    Inventors: Jeremy Martin Davis, Peter David Davis, David Festus Charles Moffat, Mark James Batchelor
  • Cell production
    Publication number: 20030134413
    Abstract: A method of producing neurectoderm cells, which method includes providing a source of early primitive ectoderm-like (EPL) cells; a conditioned medium as hereinbefore defined; or an extract therefrom exhibiting neural inducing properties; and contacting the EPL cells with the conditioned medium, for a time sufficient to generate controlled differentiation to neurectoderm cells.
    Type: Application
    Filed: December 3, 2002
    Publication date: July 17, 2003
    Inventors: Peter David Rathjen, Joy Rathjen
  • Method and apparatus for a redundant clock
    Publication number: 20030128782
    Abstract: A redundant clock system and communications cards for utilizing the system, the system including a clock source for providing a reference signal for communication cards; an alternate clock source, coupled to the clock source, for providing an alternate reference signal for the communication cards; each of the communication cards including a clock generator, referenced to one of the reference signals for providing clock signals at frequencies corresponding to functions provided by each of the communications cards, and each of the communication cards arranged to couple to a surviving one of the reference signals when a failure of the other is detected.
    Type: Application
    Filed: January 8, 2002
    Publication date: July 10, 2003
    Applicant: MOTOROLA, INC.
    Inventors: Peter David Novak, Angela Carol McCrory, Dale Emerson Ray, Toni Ann Long
  • Chrysanthemum variety 95-105-6
    Publication number: 20030126651
    Abstract: The present invention relates to new, distinct and stable cultivar of chrysanthemum.
    Type: Application
    Filed: February 14, 2000
    Publication date: July 3, 2003
    Inventors: Neil Owen Anderson, Peter David Ascher
  • CHRYSANTHEMUM PLANT NAMED 'MN95-105-6'
    Publication number: 20030126660
    Abstract: A new and distinct Chrysanthemum plant named 95-105-6 is provided. This new cultivar was the result of a unique cross between Dendranthema weyrichii and Dendranthema grandiflora.
    Type: Application
    Filed: February 14, 2000
    Publication date: July 3, 2003
    Inventors: Neil Owen Anderson, Peter David Ascher
  • CHRYSANTHEMUM PLANT NAMED '92-333-2'
    Publication number: 20030126661
    Abstract: A new and distinct Chrysanthemum plant named 92-333-2 is provided. This new cultivar was the result of a unique cross between Dendranthema weyrichii and Dendranthema grandiflora.
    Type: Application
    Filed: February 14, 2000
    Publication date: July 3, 2003
    Inventors: Neil Owen Anderson, Peter David Ascher
  • Cell production
    Publication number: 20030113901
    Abstract: A method for producing differentiated or partially differentiated neurons which method includes providing
    Type: Application
    Filed: October 24, 2001
    Publication date: June 19, 2003
    Inventors: Robert Anthony Hirst, Joy Rathjen, Peter David Rathjen
  • Methods using dry powder deposition apparatuses
    Publication number: 20030113474
    Abstract: Provided is, among other things, a dry deposition apparatus for depositing grains on a substrate comprising:
    Type: Application
    Filed: November 27, 2002
    Publication date: June 19, 2003
    Inventors: Eugene Samuel Poliniak, Hoi Cheong Steve Sun, Nitin Vithalbhai Desai, Nalin Kumar, William Ronald Roach, Lawrence Harrison Hammer, Peter David Southgate, Bawa Singh, Howard Christopher Rivenburg, Peter Zanzucchi, David Keller, Dominic Stephen Rosati
  • Method of polycarbonate preparation
    Patent number: 6576739
    Abstract: High molecular weight polycarbonates are prepared from hindered bisphenols in a reaction sequence involving conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and aqueous base to effect polymerization by hydrolysis and condensation of the bischloroformate groups. Tertiary aliphatic and cycloaliphatic amine catalysts bearing at least one methyl group are found to be especially effective in promoting this polymerization reaction. Reaction rates and selectivities are shown to be superior to known methods employing tertiary amines lacking methyl groups attached to nitrogen, such as triethylamine. The inclusion of chain stoppers allows the preparation of well defined mixtures of polycarbonate oligomers from hindered bisphenols. Additionally, the methodology may be used to prepare symmetrical diaryl carbonates from hindered phenols.
    Type: Grant
    Filed: December 14, 2000
    Date of Patent: June 10, 2003
    Assignee: General Electric Company
    Inventors: Peter David Phelps, Elliott West Shanklin, Daniel Joseph Brunelle
  • Hose and wand assembly
    Publication number: 20030101535
    Abstract: A vacuum cleaner (100) comprises a main body (3), separating apparatus, a flexible hose (20) having one end for coupling to an input of the separating apparatus and the other end terminating in a connecting part (40), a rigid pipe (9, 10) being selectively connectable to the main body (3) (see FIG. 2A) so as to provide a handle for the cleaner when connected to the main body (3), or a wand when released from the main body (3). The pipe (9) has an opening at each of first and second ends (16, 17) and a gripping portion (11) at the first end (17) for allowing a user to grasp the pipe (9). The hose connecting part (40) is connectable to the opening at either end (16, 17) of the pipe (9). Thus, the pipe (9) can be more conveniently used during a cylinder mode of cleaning.
    Type: Application
    Filed: October 28, 2002
    Publication date: June 5, 2003
    Inventors: Peter David Gammack, Jonathan Paul Taylor, Matthew James Roger Allard
  • Changover valve
    Patent number: 6572078
    Abstract: A changeover valve comprises a first valve member and a second valve member. The first value member has an aperture. The second valve member has first and second apertures. The first valve member is movable relative to the second valve member for selective alignment of the first value member aperture with one or other of the apertures of the second valve member. The value also has a ramp and follower means for automatically moving the valve member away from the one another during changeover movement of the first valve member relative to the second valve member so that wear on the surfaces of the valve members is minimized.
    Type: Grant
    Filed: April 6, 2001
    Date of Patent: June 3, 2003
    Assignee: Dyson Limited
    Inventors: Andrew Walter McRae Thomson, Peter David Gammack, Robert Brian Seaman
  • Aqueous hexasubstituted guanidinium chlorides and methods for their preparation and use
    Patent number: 6570038
    Abstract: Hexasubstituted guanidinium chlorides are prepared by a method which affords them in high yield as aqueous solutions, optionally also containing alkali metal chlorides. The solutions may be employed as sources of hexasubstituted guanidinium salts useful as phase transfer catalysts for the reaction of alkali metal salts of dihydroxyaromatic compounds with substituted imides to form polyetherimides or their intermediates.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: May 27, 2003
    Inventors: Joseph John Caringi, Peter David Phelps, Thomas Link Guggenheim, Daniel Joseph Brunelle
  • Methods for microbial regulation
    Patent number: 6555356
    Abstract: A method and microbial culture medium for inhibiting homoserine lactone and/or acylated homoserine lactone regulated processes in microorganisms using furanone compounds.
    Type: Grant
    Filed: March 4, 1998
    Date of Patent: April 29, 2003
    Assignee: Unisearch Limited
    Inventors: Staffan Kjelleberg, Peter David Steinberg, Peter Canisius De Nys, Ria Maximilien, Michael Manefield, Michael Givskov, Lone Gram
  • Method and apparatus for preparing monofunctional aromatic chloroformates suitable for use as chainstopping agents
    Publication number: 20030078449
    Abstract: The specification describes a continuous process for the preparation of monofunctional aromatic chloroformates (MAC) having the structure (I) 1
    Type: Application
    Filed: May 8, 2002
    Publication date: April 24, 2003
    Applicant: General Electric Co.
    Inventors: James Manio Silva, David Michel Dardaris, Peter David Phelps
  • 2-pyrimidineamine derivatives and processes for their preparation
    Patent number: 6552029
    Abstract: Compounds of general formula (1) are described wherein: Ar is an optionally substituted aromatic group; R2 is a hydrogen or halogen atom or a group —X1—R2a where X1 is a direct bond or a linker atom or group, and R2a is an optionally substituted straight or branched chain alkyl, alkenyl or alkynyl group; R3 is an optionally substituted heterocycloalkyl group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are selective protein tyrosine kinase inhibitors, particularly the kinases ZAP-70 and syk and are of use in the prophylaxis and treatment of immune or allergic diseases and diseases involving inappropriate platelet activation.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: April 22, 2003
    Assignee: Celltech R&D Limited
    Inventors: Peter David Davis, David Festus Charles Moffat, Mark James Batchelor, Martin Clive Hutchings, David Mark Parry
  • Neuronal rescue agent
    Publication number: 20030060398
    Abstract: This invention includes embodiments comprising activin and analogs of activin for neuronal rescue in patients having neurons that are subject to death and/or degradation as a result of neurological diseases. In certain embodiments, an activin receptor agonist can be useful for treating neuralogical diseases such as Alzheimer's Disease, Parkinson's Disease or other diseases involving neural degeneration and loss of neural function.
    Type: Application
    Filed: May 28, 2002
    Publication date: March 27, 2003
    Inventors: Peter David Gluckman, Christopher Edward Williams, Dahao Wu, Paul Edmund Hughes, Maggie Lai
  • Divided dose therapies with vascular damaging activity
    Publication number: 20030055024
    Abstract: The invention concerns the use of a vascular damaging agent or a pharmaceutically acceptable salt thereof in the manufacture of a medicament for administration in divided doses for use in the production of a vascular damaging effect in a warm-blooded animal such as a human. In particular the vascular damaging agent is ZD6126, or a pharmaceutically acceptable salt thereof. The invention also relates to methods of treatment using a vascular damaging agent in divided doses.
    Type: Application
    Filed: September 26, 2002
    Publication date: March 20, 2003
    Inventor: Peter David Davis
  • Collection chamber for a vacuum cleaner
    Patent number: D471683
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: March 11, 2003
    Assignee: Dyson Limited
    Inventors: James Dyson, Alexander Stuart Knox, Peter David Gammack, Michael David Ganderton