Abstract: The present disclosure relates to downhole fluid additives including a clay, a hydroxylated polymer, a cation, and water. The disclosure further relates to downhole fluids, including drilling fluids, spaces, cements, and proppant delivery fluids containing such as downhole fluid additive and methods of using such fluids. The downhole fluid additive may have any of a variety of functions in the downhole fluid and may confer any of a variety of properties upon it, such as salt tolerance or desired viscosities even at high downhole temperatures.

Abstract: A delivery system for an implantable medical device includes an outer shaft and an inner shaft translatable within the outer shaft. An internally exposed coil is disposed within the inner shaft and is electrically coupled to an externally exposed coil that can be used to inductively transmit a current flowing through the internally exposed coil. An actuation member extends within the inner shaft and includes a coupler, a force translation rod that extends proximally from the coupler and a plurality of push pull rods that extend distally from the coupler and that releasably couple to the implantable medical device. As the force translation rod moves relative to the internally exposed coil, an impedance varies in accordance with relative position.

Abstract: This disclosure describes an on-board oxygen generating system (OBOGS) using open loop control. An example OBOGS includes a concentrator comprising at least two beds and a controller. Each bed has a valve to pneumatically couple the bed between a supply gas source and a vent; The controller receives at least one input signal from at least one sensor aboard an aircraft, and determines a predicted oxygen concentration output from the at least two beds into the based on the received input signals. The controller controls the valves of the at least two beds based on the determined predicted oxygen concentration to adjust charge/vent ratios of the at least two beds.

Abstract: An attachment system for removably attaching together a first item and a second item, each having spaced parallel mounting strips, includes a track base, a mounting device, and a fastening blade. The track base includes two parallel rails, and at least one spanning plate connecting the rails for engaging a mounting strip of the first item to thereby attach the track base to the first item. The mounting device includes parallel rails, and at least one spanning plate connecting the rails, and a slot. The fastening blade is removably insertable into the slot to engage at least one mounting strip of the second item and attach the mounting device to the second item. The rails of the mounting device are configured to engage the rails of the track base to removably attach the mounting device to the track base.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating a mental health prediction for a patient. One of the methods includes obtaining brain data captured by one or more sensors characterizing a brain of a patient; determining a network graph from the brain data, wherein: a node of the network graph corresponds to a parcellation in the brain of the patient, and a subset of nodes of the network graph corresponds to a particular functional area of the brain; generating, for each of a plurality of nodes in the network graph, a measure of centrality of the node; generating, for the particular functional area of the brain and using the generated measures of centrality, a health score representing a measure of health of the functional area of the brain; generating a mental health prediction for the patient using the health score.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating a mental health prediction for a patient using a centrality ranking of the brain of the patient. One of the methods includes obtaining brain data of a patient, wherein the brain data comprises, for each of a plurality of pairs of parcellations formed from a set of parcellations where each pair comprises a first parcellation and a second parcellation, data characterizing a number of tracts connecting the first parcellation and the second parcellation; determining a network graph from the brain data; generating, for each of a plurality of nodes in the network graph, a measure of centrality of the node; determining a centrality ranking of the plurality of nodes of the network graph according to the respective measures of centrality; generating a mental health prediction for the patient using the determined centrality ranking.

Abstract: One axle of a hybrid vehicle is powered by an electric motor while a second axle of the vehicle is powered by a powertrain that includes an internal combustion engine. The electrically driven axle can be controlled in a speed control mode or in a torque control mode based on a driver demanded torque. The speed control mode is used when slip is detected at the electrically driven axle. The torque control mode is used when the electrically driven axle has traction. During a transition between these modes, the rate of change of torque is controlled to a predetermined level to mitigate noise, vibration, and harshness.

Abstract: A method of treating water includes directing a stream of water towards a lateral side of a water treatment substance body contained within a holder. The water stream serves to abrade the water treatment substance body, thereby to dose the water with the water treatment substance. Dosed water is thus formed. The dosed water is allowed to pass through at least one opening in the holder.

Abstract: Thermally broken fenestration systems are provided that improve performance characteristics or combinations thereof, including strength and thermal conductivity. Embodiments disclosed include one or more fenestration frame assemblies, each having an interior frame member and an exterior frame member. The interior frame members and exterior frame members are coupled together via a plurality of bridges distributed along the length of the respective fenestration frame assembly. The bridges provide structural rigidity, while providing a plurality of air gaps between interior frame member and the exterior frame member to provide a thermal break.

Abstract: A drive assembly for use with a delivery catheter for delivering an implantable medical device includes a drive motor configured to be operably coupled to an inner shaft of the delivery catheter such that operation of the drive motor causes the inner shaft to translate relative to the outer shaft and a controller. The controller is configured to receive a position signal from a position sensor indicating a position of the implantable medical device relative to the outer shaft as well as a motor signal indicating a rotational position of an output shaft of the drive motor. The controller is configured to output a control signal instructing operation of the drive motor based upon the indicated rotational position of the output shaft of the drive motor and the indicated position of the implantable medical device relative to the outer shaft.

Abstract: Single chain polypeptide fusion protein, comprising: a non-cytotoxic protease capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a galanin targeting moiety; a protease cleavage site; a translocation domain; a first spacer located between the non-cytotoxic protease and the protease cleavage site; and a second spacer located between the galanin targeting moiety and the translocation domain.

Abstract: A system and method is disclosed for performing diagnostics on patient devices. The patient devices may include respiratory therapy devices that operate in accordance with instruction sets, such as software or firmware. A server may maintain a database of diagnostic data indicating faults in one or more of a plurality of patient devices. The server may transmit this diagnostic data to one or more computing devices, including identification of faults that have occurred. The server may also transmit service data to the plurality of patient devices in order to address the identified faults.

Abstract: In various embodiments methods are provided for identifying and/or quantifying one or more antigens of interest (biomarkers) on the surface of cell- or tissue-specific exosomes.

Abstract: A removable gas sensor module is provided for a therapeutic gas delivery device. The gas sensor module includes a sample chamber which receives a sample gas from the therapeutic gas delivery device. A gas detection unit includes a plurality of sensors operable to measure at least one property of the sample gas. The sensors include two or more of a gas detection sensor, a humidity sensor, a temperature sensor, or a combination thereof. The gas sensor module is self-contained within the therapeutic gas delivery device and swappable with another gas sensor module.

Abstract: A power distribution system can include a power source, a power distribution unit, and at least one electrical load supplied by the power distribution unit. A detection circuit can be utilized in the power distribution system to sense or detect the occurrence of an electrical failure within the power or electrical unit.

Abstract: The following provides an exemplary method. An image is generated. Scan data generated by the sensing of a subject brain is received and a sequence of volumetric-images are accessed. For at least some of the voxels in at least some of the volumetric images, a change value is determined for the voxel by comparing the current-intensity value of the voxel to the adjacent-intensity value of the comparison voxel. For at least some of the plurality volumetric images, a first-aggregate is determined using at least a mean value of change values of the volumetric image and a second-aggregate is determined using at least a median value of change values of the volumetric image. At least one, but not all, of the volumetric images is determined as invalid as a result of the aggregates.

Abstract: The present invention involves a method for anonymous contact tracing for a user with a mobile device in a location having an associated contract tracing system having a plurality of tokens. The user has a mobile device upon which the user obtains a token from the location and/or the contact tracing system. The mobile device stores the user's space-time coordinate information. There is a recording of space-time coordinate information of each mobile device that is traceable by the contact tracing system in association with one of the tokens. When a user reports the existence of an exposure event, the contact tracing system analyzes the token-coordinate information to determine which of the tokens have been subject to the exposure event. By notifying at least one of the users with an associated token that was subject to the exposure event, those users may also check to see if they have been subject to the same exposure event. The method may be implemented by a server and by software running on a mobile device.

Abstract: This provides a system and method for handling the interchange of trailers between an over the road (OTR) truck and an autonomous vehicle (AV) yard truck in a facility yard includes an interchange zone (IZ) that is bounded by a predetermined boundary structure, having an OTR entry gate and an OTR exit gate on a first side and an AV entry gate and an AV exit gate on a second side. The system and method further includes a management process that selectively opens and closes each of the OTR entry gate, the OTR exit gate, the AV entry gate and the AV exit gate according to a predetermined set of rules.

Abstract: An inter-spool energy transfer system is provided and includes a first spool, a second spool, which includes components that are rotatable at a different speed as compared to components of the first spool and an inter-spool interface system coupled to at least one of the components of the first spool and at least one of the components of the second spool. The inter-spool interface system includes a controller, which is configured to supply power to one of the first and second spools and to draw power from the other of the first and second spools.