Patents by Inventor Peter Ma
Peter Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250019756Abstract: A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the chemically-enhanced primer as well as a method of preparing DNA for sequencing, a method of sequencing DNA, and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition wherein excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.Type: ApplicationFiled: June 10, 2024Publication date: January 16, 2025Inventors: Linda LEE, Sam WOO, Peter MA
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Publication number: 20250019757Abstract: According to various embodiments described herein, a microfluidics-chip based purification device and system for Sanger-sequencing reactions is provided. The device and system allow for the introduction into a sequencing system of a cartridge containing purification technologies specific to the sequencing contaminants or sequencing method where the simplified purification solution of a cartridge allows automation of the sample purification process, reduced consumption of purification reagents, and consistency in sampling by reducing the sampling errors and artifacts. These various embodiments therefore solve the need for a microfluidics-chip-based, Sanger-sequencing reaction purification system for CE devices. The microfluidic chips described can be used as a PCR chip by reorganizing the on-chip reagents, reaction wells and work flow steps.Type: ApplicationFiled: January 5, 2024Publication date: January 16, 2025Inventors: Swati Goyal, Jonathan Wang, Hans Wenz, Peter Ma, Achim Karger, S. Jeffrey Rosner, Ian Walton
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Publication number: 20240293658Abstract: A device for coupling to a fluid connector of an IV administration set to resist contamination of the fluid connector and IV administration set and permit priming of the IV administration set. The device including a cover body having a cavity for receiving the fluid connector, a priming passage for priming fluid from the IV administration set through the fluid connector, and a coupling tab extending from the cover body, the coupling tab permitting the cover body to be coupled to a length of an IV line or other portion of the IV administration set to resist contamination and permit priming of the IV administration set.Type: ApplicationFiled: May 2, 2024Publication date: September 5, 2024Inventors: Soon Yong PARK, Siddarth SHEVGOOR, Peter MA, Jiagui LI
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Patent number: 12049637Abstract: The present invention relates to cytolytic bi-component protein complexes consisting of a plurality of molecules of a member of the aegerolysin family and a plurality of molecules of a member of the MACPF superfamily, and particularly to their use for controlling a plant pest, such as for controlling Colorado potato beetle (Leptinotarsa decemlineata) or Western corn rootworm (Diabrotica virgifera virgifera). More specifically, the invention relates to cytolytic bi-component protein complexes formed by a plurality of molecules of one of the aegerolysins ostreolysin A6 (OlyA6), pleurotolysin A2 (PlyA2) and erylysin A (EryA) with a plurality of molecules of pleurotolysin B (PlyB) or similar proteins, which have been shown to be toxic for the aforementioned agricultural pest insects.Type: GrantFiled: September 29, 2017Date of Patent: July 30, 2024Assignees: KMETIJSKI INSTITUT SLOVENIJE, Univerza v LjubljaniInventors: Anastasija Panevska, Jaka Razinger, Kristina Sep{hacek over (c)}ić, Peter Ma{hacek over (c)}ek, Matej Sko{hacek over (c)}aj, {hacek over (S)}pela Modic, Maru{hacek over (s)}a Novak, Matej Butala, Vesna Hodnik, Maja Grundner, Tom Turk
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Patent number: 12011565Abstract: A device for coupling to a fluid connector of an IV administration set to resist contamination of the fluid connector and IV administration set and permit priming of the IV administration set. The device including a cover body having a cavity for receiving the fluid connector, a priming passage for priming fluid from the IV administration set through the fluid connector, and a coupling tab extending from the cover body, the coupling tab permitting the cover body to be coupled to a length of an IV line or other portion of the IV administration set to resist contamination and permit priming of the IV administration set.Type: GrantFiled: December 1, 2022Date of Patent: June 18, 2024Assignee: CAREFUSION 303, INC.Inventors: Soon Yong Park, Siddarth Shevgoor, Peter Ma, Jiagui Li
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Patent number: 12006536Abstract: A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the chemically-enhanced primer as well as a method of preparing DNA for sequencing, a method of sequencing DNA, and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition wherein excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.Type: GrantFiled: August 11, 2021Date of Patent: June 11, 2024Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Linda Lee, Sam Woo, Peter Ma
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Patent number: 11905557Abstract: According to various embodiments described herein, a microfluidics-chip based purification device and system for Sanger-sequencing reactions is provided. The device and system allow for the introduction into a sequencing system of a cartridge containing purification technologies specific to the sequencing contaminants or sequencing method where the simplified purification solution of a cartridge allows automation of the sample purification process, reduced consumption of purification reagents, and consistency in sampling by reducing the sampling errors and artifacts. These various embodiments therefore solve the need for a microfluidics-chip-based, Sanger-sequencing reaction purification system for CE devices. The microfluidic chips described can be used as a PCR chip by reorganizing the on-chip reagents, reaction wells and work flow steps.Type: GrantFiled: March 5, 2021Date of Patent: February 20, 2024Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Swati Goyal, Achim Karger, Peter Ma, S. Jeffrey Rosner, Ian Walton, Jonathan Wang, Michael Wenz
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Publication number: 20230091073Abstract: A device for coupling to a fluid connector of an IV administration set to resist contamination of the fluid connector and IV administration set and permit priming of the IV administration set. The device including a cover body having a cavity for receiving the fluid connector, a priming passage for priming fluid from the IV administration set through the fluid connector, and a coupling tab extending from the cover body, the coupling tab permitting the cover body to be coupled to a length of an IV line or other portion of the IV administration set to resist contamination and permit priming of the IV administration set.Type: ApplicationFiled: December 1, 2022Publication date: March 23, 2023Inventors: Soon PARK, Siddarth Shevgoor, Peter Ma, Jiagui Li
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Patent number: 11529507Abstract: A device for coupling to a fluid connector of an IV administration set to resist contamination of the fluid connector and IV administration set and permit priming of the IV administration set. The device including a cover body having a cavity for receiving the fluid connector, a priming passage for priming fluid from the IV administration set through the fluid connector, and a coupling tab extending from the cover body, the coupling tab permitting the cover body to be coupled to a length of an IV line or other portion of the IV administration set to resist contamination and permit priming of the IV administration set.Type: GrantFiled: August 31, 2018Date of Patent: December 20, 2022Assignee: CareFusion 303, Inc.Inventors: Soon Park, Siddarth K. Shevgoor, Peter Ma, Jiagui Li
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Publication number: 20220049289Abstract: A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the chemically-enhanced primer as well as a method of preparing DNA for sequencing, a method of sequencing DNA, and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition wherein excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.Type: ApplicationFiled: August 11, 2021Publication date: February 17, 2022Inventors: Linda LEE, Sam WOO, Peter MA
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Publication number: 20220051089Abstract: The technology relates to a neural network dual in-line memory module (NN-DIMM), a microelectronic system comprising a CPU and a plurality of the NN-DIMMs, and a method of transferring information between the CPU and the plurality of the NN-DIMMS. The NN-DIMM may include a module card having a plurality of parallel edge contacts adjacent to an edge of a slot connector thereof and configured to have the same command and signal interface as a standard dual in-line memory module (DIMM). The NN-DIMM may also include a deep neural network (DNN) accelerator affixed to the module card, and a bridge configured to transfer information between the DNN accelerator and the plurality of parallel edge contacts via a DIMM external interface.Type: ApplicationFiled: August 17, 2020Publication date: February 17, 2022Inventors: Doe Hyun Yoon, Lifeng Nai, Peter Ma
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Publication number: 20210363063Abstract: A non-spray-dried, dry-granulated ceramic particulate mixture including at least 40 wt % coal combustion fly ash and from 4 wt % to 9 wt % water. At least 90 wt % of the particles have a particle size of from 80 ?m to 600 ?m.Type: ApplicationFiled: October 15, 2019Publication date: November 25, 2021Applicant: VECOR IP HOLDINGS LIMITEDInventors: Sandor Koszo, Peter Ma, Ahmed Badran
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Publication number: 20210323871Abstract: A non-spray-drying, dry-granulation process for making a ceramic particulate mixture including from 4 wt % to 9 wt % water. At least 90 wt % of the particles have a particle size of from 80 ?m to 600 ?m. The process includes the steps of: (a) forming a precursor material; (b) subjecting the precursor material to a compaction step to form a compacted precursor material; (c) subjecting the compacted precursor material to a crushing step to form a crushed precursor material; and (d) subjecting the crushed precursor material to at least two air classification steps. One air classification step removes at least a portion of the particles having a particle size of greater than 600 ?m from the crushed precursor material, and the other air classification step removes at least a portion of the particles having a particle size of less than 80 ?m from the crushed precursor material.Type: ApplicationFiled: October 15, 2019Publication date: October 21, 2021Applicant: VECOR IP HOLDINGS LIMITEDInventors: Sandor Koszo, Peter Ma, Ahmed Badran
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Publication number: 20210269871Abstract: According to various embodiments described herein, a microfluidics-chip based purification device and system for Sanger-sequencing reactions is provided. The device and system allow for the introduction into a sequencing system of a cartridge containing purification technologies specific to the sequencing contaminants or sequencing method where the simplified purification solution of a cartridge allows automation of the sample purification process, reduced consumption of purification reagents, and consistency in sampling by reducing the sampling errors and artifacts. These various embodiments therefore solve the need for a microfluidics-chip-based, Sanger-sequencing reaction purification system for CE devices. The microfluidic chips described can be used as a PCR chip by reorganizing the on-chip reagents, reaction wells and work flow steps.Type: ApplicationFiled: March 5, 2021Publication date: September 2, 2021Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Swati GOYAL, Achim KARGER, Peter MA, S. Jeffrey ROSNER, Ian WALTON, Jonathan WANG, Michael WENZ
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Patent number: 11104944Abstract: A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the chemically-enhanced primer as well as a method of preparing DNA for sequencing, a method of sequencing DNA, and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition wherein excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.Type: GrantFiled: January 14, 2019Date of Patent: August 31, 2021Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Linda Lee, Sam Woo, Peter Ma
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Publication number: 20200069933Abstract: A device for coupling to a fluid connector of an IV administration set to resist contamination of the fluid connector and IV administration set and permit priming of the IV administration set. The device including a cover body having a cavity for receiving the fluid connector, a priming passage for priming fluid from the IV administration set through the fluid connector, and a coupling tab extending from the cover body, the coupling tab permitting the cover body to be coupled to a length of an IV line or other portion of the IV administration set to resist contamination and permit priming of the IV administration set.Type: ApplicationFiled: August 31, 2018Publication date: March 5, 2020Inventors: Soon PARK, Siddarth K. SHEVGOOR, Peter MA, Jiagui LI
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Patent number: D892319Type: GrantFiled: August 31, 2018Date of Patent: August 4, 2020Assignee: CareFusion 303, Inc.Inventors: Soon Park, Siddarth K. Shevgoor, Peter Ma, Jiagui Li
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Patent number: D925734Type: GrantFiled: July 27, 2020Date of Patent: July 20, 2021Assignee: CareFusion 303, Inc.Inventors: Soon Park, Siddarth K. Shevgoor, Peter Ma, Jiagui Li
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Patent number: D958338Type: GrantFiled: July 16, 2021Date of Patent: July 19, 2022Assignee: CareFusion 303, Inc.Inventors: Soon Park, Siddarth K. Shevgoor, Peter Ma, Jiagui Li
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Patent number: D996613Type: GrantFiled: June 15, 2022Date of Patent: August 22, 2023Assignee: CareFusion 303, Inc.Inventors: Soon Park, Siddarth K. Shevgoor, Peter Ma, Jiagui Li