Patents by Inventor Peter Ma

Peter Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200069933
    Abstract: A device for coupling to a fluid connector of an IV administration set to resist contamination of the fluid connector and IV administration set and permit priming of the IV administration set. The device including a cover body having a cavity for receiving the fluid connector, a priming passage for priming fluid from the IV administration set through the fluid connector, and a coupling tab extending from the cover body, the coupling tab permitting the cover body to be coupled to a length of an IV line or other portion of the IV administration set to resist contamination and permit priming of the IV administration set.
    Type: Application
    Filed: August 31, 2018
    Publication date: March 5, 2020
    Inventors: Soon PARK, Siddarth K. SHEVGOOR, Peter MA, Jiagui LI
  • Publication number: 20190211373
    Abstract: A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the chemically-enhanced primer as well as a method of preparing DNA for sequencing, a method of sequencing DNA, and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition wherein excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.
    Type: Application
    Filed: January 14, 2019
    Publication date: July 11, 2019
    Inventors: Linda Lee, Sam Woo, Peter Ma
  • Patent number: 9708650
    Abstract: A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the chemically-enhanced primer as well as a method of preparing DNA for sequencing, a method of sequencing DNA, and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition wherein excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.
    Type: Grant
    Filed: March 5, 2014
    Date of Patent: July 18, 2017
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Linda Lee, Sam Woo, Peter Ma
  • Publication number: 20170051344
    Abstract: According to various embodiments described herein, a microfiuidics-chip based purification device and system for Sanger-sequencing reactions is provided. The device and system allow for the introduction into a sequencing system of a cartridge containing purification technologies specific to the sequencing contaminants or sequencing method where the simplified purification solution of a cartridge allows automation of the sample purification process, reduced consumption of purification reagents, and consistency in sampling by reducing the sampling errors and artifacts. These various embodiments therefore solve the need for a microfiuidics-chip-based, Sanger-sequencing reaction purification system for CE devices. The microfiuidic chips described can be used as a PCR chip by reorganizing the on-chip reagents, reaction wells and work flow steps.
    Type: Application
    Filed: January 23, 2015
    Publication date: February 23, 2017
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Swati Goyal, Achim Karger, Peter Ma, S. Jeffrey Rosner, Ian Walton, Jonathan Wang, Michael Wenz
  • Publication number: 20170051342
    Abstract: A composition is provided comprising a negatively charged group, an oligonucleotide sequence and at least none or one nuclease-resistant linkage group to form a chemically-enhanced primer. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the primer as well as a method of preparing DNA for sequencing and a method of sequencing DNA and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition under conditions in which excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.
    Type: Application
    Filed: August 8, 2016
    Publication date: February 23, 2017
    Inventors: LINDA LEE, Sam WOO, Peter MA
  • Publication number: 20160321690
    Abstract: A method of providing advertising on a mobile device is provided. The method provides an advertising control interface area as a top layer on an application interface layer of an application executing on the mobile device. The user launches full advertisements which generally consume more display space than the advertising control interface area by performing an advertising control interface area selection gesture. A user advertisement queue is dynamically updated as the user views full advertisements. Once the user views all of the advertisements in the queue, the advertisement control interface area is removed from the display for a selected period of time, providing full access to the entirety of the application interface area, which incentivizes mobile device users to view the full advertisements in their queue.
    Type: Application
    Filed: April 30, 2015
    Publication date: November 3, 2016
    Inventor: Peter Ma
  • Patent number: 9410192
    Abstract: A composition is provided comprising a negatively charged group, an oligonucleotide sequence and at least none or one nuclease-resistant linkage group to form a chemically-enhanced primer. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the primer as well as a method of preparing DNA for sequencing and a method of sequencing DNA and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition under conditions in which excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: August 9, 2016
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Linda Lee, Sam Woo, Peter Ma
  • Publication number: 20160096153
    Abstract: Systems and methods of manipulating discrete volumes of a first fluid in a second fluid are provided. In some embodiments, discrete volumes can be formed in a conduit. In other embodiments, addition fluid can be added to a discrete volume in a first conduit by injecting the addition fluid at a relatively higher pressure. In some embodiments, discrete volumes that normally would not coalesce can be manipulated to be merged together.
    Type: Application
    Filed: September 11, 2015
    Publication date: April 7, 2016
    Inventors: Linda G. Lee, Mark F. Oldham, Sam L. Woo, David M. Cox, Richard T. Reel, Peter Ma, Ben Johnson, Dennis Lehto
  • Patent number: 9292264
    Abstract: A software development kit for providing advertising in a mobile device user interface is provided. The software development kit includes computer executable program instructions for generating a wrapper view object that wraps an advertising corner control view object. The kit allows an application developer to create an application interface and wrap it in the wrapper view object. When the resulting computer executable instructions are executed, a user interface is displayed with an advertising corner control interface area and an application interface area. The user can select the advertising corner control interface area using a first selection technique to display an advertising interface area and remove the advertising control interface area and the application interface area. The user can select the advertising corner control interface area using a second technique to remove the application corner control interface area while continuing to display the application interface area.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 22, 2016
    Assignee: Paschar LLC
    Inventor: Peter Ma
  • Publication number: 20150095160
    Abstract: A method of providing advertising on a mobile device having a plurality of applications is provided by executing a set of computer executable advertising instructions stored on the mobile device. The instructions are stored as part of an operating system or a secondary application that can run in the background and are capable of identifying an application executing in the foreground. The instructions are stored separately from the executable code for the applications on which advertising is displayed. As a result, application developers can subscribe to an advertising service that displays advertising on their application interfaces without creating any code.
    Type: Application
    Filed: October 1, 2013
    Publication date: April 2, 2015
    Applicant: Paschar LLC
    Inventor: Peter Ma
  • Publication number: 20140377747
    Abstract: A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the chemically-enhanced primer as well as a method of preparing DNA for sequencing, a method of sequencing DNA, and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition wherein excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.
    Type: Application
    Filed: March 5, 2014
    Publication date: December 25, 2014
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Linda LEE, Sam Woo, Peter Ma
  • Publication number: 20140279029
    Abstract: A software development kit for providing advertising in a mobile device user interface is provided. The software development kit includes computer executable program instructions for generating a wrapper view object that wraps an advertising corner control view object. The kit allows an application developer to create an application interface and wrap it in the wrapper view object. When the resulting computer executable instructions are executed, a user interface is displayed with an advertising corner control interface area and an application interface area. The user can select the advertising corner control interface area using a first selection technique to display an advertising interface area and remove the advertising control interface area and the application interface area. The user can select the advertising corner control interface area using a second technique to remove the application corner control interface area while continuing to display the application interface area.
    Type: Application
    Filed: May 3, 2013
    Publication date: September 18, 2014
    Applicant: Paschar LLC
    Inventor: Peter Ma
  • Publication number: 20140282126
    Abstract: A software development kit for providing advertising in a mobile device user interface is provided. The software development kit includes computer executable program instructions for generating a wrapper view object that wraps an advertising corner control view object. The kit allows an application developer to create an application interface and wrap it in the wrapper view object. When the resulting computer executable instructions are executed, a user interface is displayed with an advertising corner control interface area and an application interface area. The user can select the advertising corner control interface area using a first selection technique to display an advertising interface area and remove the advertising control interface area and the application interface area. The user can select the advertising corner control interface area using a second technique to remove the application corner control interface area while continuing to display the application interface area.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: PASCHAR LLC
    Inventor: Peter Ma
  • Patent number: 8703925
    Abstract: A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the chemically-enhanced primer as well as a method of preparing DNA for sequencing, a method of sequencing DNA, and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition wherein excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: April 22, 2014
    Assignee: Life Technologies Corporation
    Inventors: Linda Lee, Sam Woo, Peter Ma
  • Publication number: 20140099645
    Abstract: A composition is provided comprising a negatively charged group, an oligonucleotide sequence and at least none or one nuclease-resistant linkage group to form a chemically-enhanced primer. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the primer as well as a method of preparing DNA for sequencing and a method of sequencing DNA and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition under conditions in which excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.
    Type: Application
    Filed: October 14, 2013
    Publication date: April 10, 2014
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Linda LEE, Sam WOO, Peter MA
  • Publication number: 20130344492
    Abstract: In one aspect, there are provided methods of amplifying and sequencing a polynucleotide. In some embodiments, the method includes (a) amplifying the polynucleotide with at least one amplification primer, a processive amplification polymerase, a sequencing primer, a sequencing polymerase, deoxynucleoside triphosphates suitable for template-dependent primer extension, and one or more terminating nucleotides, the incubation being carried out at a first temperature suitable for amplifying the polynucleotide with the processive amplification polymerase; (b) incubating the product of step (a) at a second temperature suitable for forming a plurality of differently-sized extended sequencing primers with the sequencing polymerase; (c) evaluating the extended sequencing primers in order to determine the sequence of the polynucleotide. The reactions at the first and second temperatures can be carried out in a single reaction vessel. In other aspects, compositions and kits for carrying out the methods are also provided.
    Type: Application
    Filed: June 12, 2013
    Publication date: December 26, 2013
    Inventor: Peter MA
  • Publication number: 20120270211
    Abstract: A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the chemically-enhanced primer as well as a method of preparing DNA for sequencing, a method of sequencing DNA, and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition wherein excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.
    Type: Application
    Filed: February 15, 2012
    Publication date: October 25, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Linda LEE, Sam WOO, Peter MA
  • Publication number: 20120135414
    Abstract: A composition is provided comprising a negatively charged group, an oligonucleotide sequence and at least none or one nuclease-resistant linkage group to form a chemically-enhanced primer. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the primer as well as a method of preparing DNA for sequencing and a method of sequencing DNA and kits containing the chemically-enhanced primer are also provided. The method of sequencing DNA can comprise contacting amplification reaction products with the composition under conditions in which excess amplification primer is degraded by the nuclease and the chemically-enhanced primer is essentially non-degraded.
    Type: Application
    Filed: October 28, 2011
    Publication date: May 31, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Linda LEE, Sam Lee Woo, Peter Ma
  • Publication number: 20110070580
    Abstract: In one aspect, there are provided methods of amplifying and sequencing a polynucleotide. In some embodiments, the method includes (a) amplifying the polynucleotide with at least one amplification primer, a processive amplification polymerase, a sequencing primer, a sequencing polymerase, deoxynucleoside triphosphates suitable for template-dependent primer extension, and one or more terminating nucleotides, the incubation being carried out at a first temperature suitable for amplifying the polynucleotide with the processive amplification polymerase; (b) incubating the product of step (a) at a second temperature suitable for forming a plurality of differently-sized extended sequencing primers with the sequencing polymerase; (c) evaluating the extended sequencing primers in order to determine the sequence of the polynucleotide. The reactions at the first and second temperatures can be carried out in a single reaction vessel. In other aspects, compositions and kits for carrying out the methods are also provided.
    Type: Application
    Filed: January 7, 2010
    Publication date: March 24, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventor: Peter Ma
  • Patent number: D892319
    Type: Grant
    Filed: August 31, 2018
    Date of Patent: August 4, 2020
    Assignee: CareFusion 303, Inc.
    Inventors: Soon Park, Siddarth K. Shevgoor, Peter Ma, Jiagui Li