Abstract: The present invention relates to electric drivetrain kits for converting all-terrain vehicles into hybrid or electric vehicles. In exemplary embodiments, a conversion kit replaces an existing standard single motor and transmission drive system with a dual set-up including a motor for each rear wheel and a split transmission that houses two sets of gear reduction components in a single housing or an all-wheel configuration with two transmission sets (front and rear). Dual output shafts in each transmission set drive the wheels independently to provide the torque needed as required and demanded by each wheel. System electronics send signals to the motors and other components to manage the system and independently control each wheel.

Abstract: Isoxazoles of formula (A) or (B) are inhibitors of HSP90 activity, and useful for treatment of, for example cancers: wherein R1, is a group of formula (IA): —Ar1-(Alk1)p-(Z)r-(Alk2)s-Q, wherein in any compatible combination Ar1 is an optionally substituted aryl or heteroaryl radical, Alk1 and Alk2 are optionally substituted divalent C1-C6 alkylene or C2-C6 alkenylene radicals, p, r and s are independently 0 or 1, Z is -0-, —S—, —(C?O)—, —(C?S)—, —SO.sub.

Abstract: Generally described, the present disclosure relates to communications and more particularly, to a system providing relevant services to transient devices in wireless networks and methods thereof. In one illustrative embodiment, a Unified Communications and Collaboration (UCC) client on a device can be synchronized with a network so that the device can appear as a local entity. The UCC client can facilitate exchange of data to ease the integration of the device into the local environment. After being synchronized, the UCC client can seek out available assistance from the local network and provide it to the user. Typically, the data retrieved from the local network pertains to the current location. The local network can be used to provide wireless service to mobile devices in order to remove them from their carrier network, including providing a local breakout via a Private Branch Exchange (PBX).

Abstract: A control method and related apparatus are disclosed for controlling actuation voltages applied to array elements of an element array on an electrowetting on dielectric (EWOD) device, wherein test metrics are determined and employed for optimizing subsequent droplet manipulation operations. The control method includes the steps of: receiving a liquid droplet onto the element array; applying an electrowetting actuation pattern of actuation voltages to actuate the droplet to modify a footprint of the droplet from a first state having an initial footprint to a second state having a modified footprint; sensing the modified footprint with a sensor; determining a test metric from sensing the modified footprint indicative of one or more droplet properties based on a droplet response of the liquid droplet to the electrowetting actuation pattern; and controlling actuation voltages applied to the array elements based on the test metric.

Abstract: The present invention relates to specific antibodies and use thereof, such as for identifying and/or quantifying liraglutide fibrils and/or semaglutide fibrils.

Abstract: Disclosed herein are methods and systems for monitoring and detecting changes in files attached to incoming emails. In one embodiment, if files are attached to an outgoing email, the change service uniquely tags each of the attached files and optionally stores local or remote copies of the tagged files. Additionally, in embodiments, the change service monitors and intercepts incoming emails. If files are attached to an incoming email, the change service identifies whether the files are tagged in a manner unique to the compare service. The change service then matches uniquely tagged files in the incoming email to corresponding files previously tagged by the change service. The change service then compares the two documents and generates reports that identify changes in the received document in relation to the transmitted document. Further, in embodiments, the change service provides visual indicators of the changes within the email application.

Abstract: A system for creating surrogate models is provided. The system includes a user computing device including a user interface, a database, and a processor. The processor is configured to receive, from the user computing device, a workflow request, determine at least one application in the database required to complete the workflow request, retrieve, from the database, the at least one application and meta-data associated with the at least one application, and determine that a user has proper tenancies to use the at least one application. The processor is further configured to execute, using the at least one application on an external computing device, a workflow associated with the workflow request based at least in part on the meta-data, generate, based on execution of the workflow request, new meta-data associated with the at least one application, and transmit the new meta-data to the database.

Abstract: The subject matter describes devices, networks, systems, media, and methods to create secure communications between wireless devices and cellular networks, where the wireless devices communicate with the cellular networks via multi-hopping methods in wireless networks.

Abstract: The present invention relates to electric drivetrain kits for converting all-terrain vehicles into hybrid or electric vehicles. In exemplary embodiments, a conversion kit replaces an existing standard single motor and transmission drive system with a dual set-up including a motor for each rear wheel and a split transmission that houses two sets of gear reduction components in a single housing or an all-wheel configuration with two transmission sets (front and rear). Dual output shafts in each transmission set drive the wheels independently to provide the torque needed as required and demanded by each wheel.

Abstract: A wireless broadcasting device, systems including the device, and methods of programming and using the device are disclosed. The wireless broadcasting device is powered using power over Ethernet and can be used to provide proximity-based capabilities to devices that otherwise do not have such functions.

Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to 5-[[4-[[morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2-pyridyl]amino]pyrazine-2-carbonitrile compounds (referred to herein as “TFM compounds”) which, inter alia, inhibit Checkpoint Kinase 1 (CHK1) kinase function. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit CHK1 kinase function, and in the treatment of diseases and conditions that are mediated by CHK1, that are ameliorated by the inhibition of CHK1 kinase function, etc., including proliferative conditions such as cancer, etc.

Abstract: The subject matter describes devices, networks, systems, media, and methods to create secure communications between wireless devices and cellular networks, where the wireless devices communicate with the cellular networks via multi-hopping methods in non-cellular networks.

Abstract: Disclosed herein are methods and systems for monitoring and detecting changes in files attached to incoming emails. In one embodiment, if files are attached to an outgoing email, the change service uniquely tags each of the attached files and optionally stores local or remote copies of the tagged files. Additionally, in embodiments, the change service monitors and intercepts incoming emails. If files are attached to an incoming email, the change service identifies whether the files are tagged in a manner unique to the compare service. The change service then matches uniquely tagged files in the incoming email to corresponding files previously tagged by the change service. The change service then compares the two documents and generates reports that identify changes in the received document in relation to the transmitted document. Further, in embodiments, the change service provides visual indicators of the changes within the email application.

Abstract: A drive assembly for portable, hand-held, battery powered tools is provided. The tool may be configured as a crimping tool, a cutting tool or other type of tool. The tool has an in-line handle assembly and a working head assembly. The drive assembly includes a drive assembly housing, a gear assembly, a lead drive shaft and a bearing system. The gear assembly is a multi-stage gear assembly having an input tier and an output tier. The input tier is operatively connected to a motor and the output tier is connected to a lead drive shaft. The lead drive shaft has a proximal end extending into a distal end portion of the drive assembly housing. The bearing system is positioned within the drive assembly housing adjacent the output tier of the gear assembly. The bearing system is interactive with the lead drive shaft enabling the drive assembly to withstand radial and axial loads as the lead drive shaft is rotated during an operation of the tool.

Abstract: Trigger activated tools are provided that have one or more activation lockouts. The activation lockouts include electrical resets, variable position lockouts, mechanical lockouts, shield lockouts, and any combinations thereof.

Abstract: A pore analysis method is described which comprises the steps of generating a model of a medium, the model comprising a regular array of pores, the pores being connected to adjacent ones of the pores by throats, modifying the sizes of the pores and throats until the model of the medium is representative of the medium, simulating, using the model, the effect of percolation of the medium using a fluid at a first pressure, repeating the simulation step with progressively increasing intrusion pressures and noting, for each pore, the intrusion pressure at which intrusion of that pore occurs, and identifying, from the information relating to the intrusion pressure at which intrusion of each pore occurs and from the shape of the void size distribution, at least one pore that should be treated, during further analysis, as comprising a cluster of voids.

Abstract: A portable, hand held hydraulic cutting tool having an in-line handle assembly and a working head assembly. The handle assembly has a tool frame portion and a neck portion. The working head assembly has a pair of jaw members joined so that they are movable relative to each other and held in place by a locking pin. Each jaw member has a cutting blade attached thereto. Each jaw member can be tapered and can include weight reducing pockets defined in respective sidewalls. Each jaw member includes a raised tab on an outside edge that mates with a respective tab notch in a yoke of the neck portion of the handle assembly. When the locking pin is in an extended position, the jaw members of the tool can separate and rotate away from one another until their respective locking tabs engage their respective locking tab opening, connecting the jaw members to the yoke of the neck portion of the handle assembly.

Abstract: Aspects of the present disclosure include systems and methods for injecting content into a webpage at or local to a network access gateway. For example, in an embodiment, a network access gateway is provided for accessing the internet. A user logs onto the internet through the network access gateway and request a webpage. The gateway requests the webpage from the webpage provider. Before the gateway delivers the webpage to the user, the gateway, or a content injection engine local to the gateway, injects content, such as, for example, advertisements or other useful information, into the webpage and then sends the altered webpage to the user.

Abstract: Trigger activated tools are provided that have one or more activation lockouts. The activation lockouts include electrical resets, variable position lockouts, mechanical lockouts, shield lockouts, and any combinations thereof.

Abstract: The subject matter describes software, devices, networks, and methods to configure a wireless device to establish two or more concurrent wireless links in a wireless network. Embodiments disclosed herein relate to use of computing and communication resources to perform multi-hop wireless communication and to expand the coverage of cellular networks.