Abstract: A portable, hand held hydraulic cutting tool having an in-line handle assembly and a working head assembly. The handle assembly has a tool frame portion and a neck portion. The working head assembly has a pair of jaw members joined so that they are movable relative to each other and held in place by a locking pin. Each jaw member has a cutting blade attached thereto. Each jaw member can be tapered and can include weight reducing pockets defined in respective sidewalls. Each jaw member includes a raised tab on an outside edge that mates with a respective tab notch in a yoke of the neck portion of the handle assembly. When the locking pin is in an extended position, the jaw members of the tool can separate and rotate away from one another until their respective locking tabs engage their respective locking tab opening, connecting the jaw members to the yoke of the neck portion of the handle assembly.

Abstract: The present invention relates to specific antibodies and use thereof, such as for identifying and/or quantifying liraglutide fibrils and/or semaglutide fibrils.

Abstract: A pore analysis method is described which comprises the steps of generating a model of a medium, the model comprising a regular array of pores, the pores being connected to adjacent ones of the pores by throats, modifying the sizes of the pores and throats until the model of the medium is representative of the medium, simulating, using the model, the effect of percolation of the medium using a fluid at a first pressure, repeating the simulation step with progressively increasing intrusion pressures and noting, for each pore, the intrusion pressure at which intrusion of that pore occurs, and identifying, from the information relating to the intrusion pressure at which intrusion of each pore occurs and from the shape of the void size distribution, at least one pore that should be treated, during further analysis, as comprising a cluster of voids.

Abstract: Aspects of the present disclosure include systems and methods for injecting content into a webpage at or local to a network access gateway. For example, in an embodiment, a network access gateway is provided for accessing the internet. A user logs onto the internet through the network access gateway and request a webpage. The gateway requests the webpage from the webpage provider. Before the gateway delivers the webpage to the user, the gateway, or a content injection engine local to the gateway, injects content, such as, for example, advertisements or other useful information, into the webpage and then sends the altered webpage to the user.

Abstract: The subject matter describes software, devices, networks, and methods to configure a non-cellular interface of a wireless device to establish two or more wireless links in a hybrid of cellular network and a non-cellular network. The advantage of concurrent uses of non-cellular interfaces maximizes the use of computing and communication resources to perform multi-hop communication and to expand the coverage of cellular networks.

Abstract: Semi-passive control system (10) comprises a pneumatic spring actuator (16), a pressure regulator (22) in communication with the pneumatic spring actuator (16), a hydraulic locking actuator (18), a hydraulic valve (20) in communication with actuator (18), a power source (14), a pulley wheel (42), and a cable (46) having a first end in contact with pulley wheel (42), first and second side portions (50, 56) extending from opposing sides of pulley wheel (42), and a second end adapted to connect to an orthosis device (76). At least one cable clamp (62) attaches to second side portion (56) of cable (46) and interconnects cable (46) to shafts (112b, 118b) of actuators (16, 18). A central control unit (12) includes a processor (13a) and a computer readable storage medium (13b) having program instructions stored thereon for execution by the central control unit to adjust stiffness, damping or stiffness and damping parameters.

Abstract: Trigger activated tools are provided that have one or more activation lockouts. The activation lockouts include electrical resets, variable position lockouts, mechanical lockouts, shield lockouts, and any combinations thereof.

Abstract: The subject matter describes devices, networks, systems, media, and methods to create secure communications between wireless devices and cellular networks, where the wireless devices communicate with the cellular networks via multi-hopping methods in non-cellular networks.

Abstract: A crimp tool includes a frame, a lead screw and a nut assembly connected to the lead screw. A spring member is connected to the frame and movable with rotation of the lead screw. A first transducer is connected to the nut assembly to measure a first force applied on the nut assembly. A second transducer is connected to the spring member to measure a second force applied thereon by the spring member.

Abstract: Trigger activated tools are provided that have one or more activation lockouts. The activation lockouts include electrical resets, variable position lockouts, mechanical lockouts, shield lockouts, and any combinations thereof.

Abstract: The subject matter describes devices, networks, systems, media, and methods to create secure communications between wireless devices and cellular networks, where the wireless devices communicate with the cellular networks via multi-hopping methods in non-cellular networks.

Abstract: An in-line portable, handheld hydraulic scissor-type action crimping tool having a handle assembly and a working head assembly is provided. The handle assembly has a tool frame portion and a neck portion. The working head assembly has a pair of jaw members joined so that they are movable relative to each other and held in place by a locking pin. One jaw member has a nest secured to or directly formed into the jaw member. The other jaw member has an indentor secured to or directly formed into the jaw member.

Abstract: Disclosed herein are methods and systems for monitoring and detecting changes in files attached to incoming emails. In one embodiment, if files are attached to an outgoing email, the change service uniquely tags each of the attached files and optionally stores local or remote copies of the tagged files. Additionally, in embodiments, the change service monitors and intercepts incoming emails. If files are attached to an incoming email, the change service identifies whether the files are tagged in a manner unique to the compare service. The change service then matches uniquely tagged files in the incoming email to corresponding files previously tagged by the change service. The change service then compares the two documents and generates reports that identify changes in the received document in relation to the transmitted document. Further, in embodiments, the change service provides visual indicators of the changes within the email application.

Abstract: A control method and related apparatus are disclosed for controlling actuation voltages applied to array elements of an element array on an electrowetting on dielectric (EWOD) device, wherein test metrics are determined and employed for optimizing subsequent droplet manipulation operations. The control method includes the steps of: receiving a liquid droplet onto the element array; applying an electrowetting actuation pattern of actuation voltages to actuate the droplet to modify a footprint of the droplet from a first state having an initial footprint to a second state having a modified footprint; sensing the modified footprint with a sensor; determining a test metric from sensing the modified footprint indicative of one or more droplet properties based on a droplet response of the liquid droplet to the electrowetting actuation pattern; and controlling actuation voltages applied to the array elements based on the test metric.

Abstract: Nucleic acid constructs and methods for rendering modifications to a genome are provided, wherein the modifications comprise null alleles, conditional alleles and null alleles comprising COINs. Multifunctional alleles (MFA) are provided, as well as methods for making them, which afford the ability in a single targeting to introduce an allele that can be used to generate a null allele, a conditional allele, or an allele that is a null allele and that further includes a COIN. MFAs comprise pairs of cognate recombinase recognition sites, an actuating sequence and/or a drug selection cassette, and a nucleotide sequence of interest, and a COIN, wherein upon action of a recombinase a conditional allele with a COIN is formed. In a further embodiment, action of a second recombinase forms an allele that contains only a COIN in sense orientation. In a further embodiment, action by a third recombinase forms an allele that contains only the actuating sequence in sense orientation.

Abstract: An apparatus including an open interconnected wall structure having one or more pores, the open interconnected wall structure including a first electrode material, the pores including an electrolyte and a second electrode material, wherein the electrolyte and second electrode material are supported on the first electrode material within the pores such that the first electrode material is separated from the second electrode material by the electrolyte to enable the generation and/or storage of electrical energy using the apparatus.

Abstract: A crimp tool includes a frame, a lead screw and a nut assembly connected to the lead screw. A spring member is connected to the frame and movable with rotation of the lead screw. A first transducer is connected to the nut assembly to measure a first force applied on the nut assembly. A second transducer is connected to the spring member to measure a second force applied thereon by the spring member.

Abstract: An apparatus including an open interconnected wall structure having one or more pores, the open interconnected wall structure including a first electrode material, the pores including an electrolyte and a second electrode material, wherein the electrolyte and second electrode material are supported on the first electrode material within the pores such that the first electrode material is separated from the second electrode material by the electrolyte to enable the generation and/or storage of electrical energy using the apparatus.

Abstract: Isoxazoles of formula (A) or (B) are inhibitors of HSP90 activity, and useful for treatment of, for example cancers: wherein R1, is a group of formula (IA): —Ar1-(Alk1)p-(Z)r-(Alk2)s-Q, wherein in any compatible combination Ar1 is an optionally substituted aryl or heteroaryl radical, Alk1 and Alk2 are optionally substituted divalent C1-C6 alkylene or C2-C6 alkenylene radicals, p, r and s are independently 0 or 1, Z is -0-, —S—, —(C?O)—, —(C?S)—, —SO.sub.

Abstract: Disclosed herein are methods and systems for monitoring and detecting changes in files attached to incoming emails. In one embodiment, if files are attached to an outgoing email, the change service uniquely tags each of the attached files and optionally stores local or remote copies of the tagged files. Additionally, in embodiments, the change service monitors and intercepts incoming emails. If files are attached to an incoming email, the change service identifies whether the files are tagged in a manner unique to the compare service. The change service then matches uniquely tagged files in the incoming email to corresponding files previously tagged by the change service. The change service then compares the two documents and generates reports that identify changes in the received document in relation to the transmitted document. Further, in embodiments, the change service provides visual indicators of the changes within the email application.