Abstract: A method and system are provided for synchronizing local clocks more quickly in a telecommunication network using IEEE 1588. A network element that receives timing signals from one or more possible parent clocks considers a measure of the reliability of the timing signals contained in Announce messages from the parent clock or clocks. The clock uses this reliability information in selecting one of the possible parent clock or clocks to use as the actual parent clock. Once the selection is made, the clock adjusts the filtering characteristics applied to timing signals received from the selected parent clock. The adjustments reflect how confident the parent clock is as to how stable the timing information it provides has become. If the indication of reliability contained in Announce messages received from the parent clock indicates that the timing information is not very reliable, then a high filter bandwidth is used in filtering the timing signals.

Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclosed.

Abstract: The present invention relates to pellets for use in the manufacture of glass.

Abstract: Headwear reduces radiation exposure with a brim on a top crown that generally surrounds the head. The brim is above a bottom of the crown to avoid interfering with the ears, face, and/or adjustment strap of the cap, which may be of critical importance for those needing protection from sunlight. Brims are positionable a half-inch or more above the bottom of the crown and may completely or partially extend about the crown. Brims may extend at an angle of 20-degrees or more to provide clearance for the ears, face, and any adjustment structure. Brims may be integral with or nondestructively removable from the crown and may include bands or cut-outs for existing brims, bills, or adjustment structures for fitting of hats to which removable brims are added. Headwear may be rigid or a flexible canvas.

Abstract: The present invention generally relates to phenethyldihydrobenzodioxolone compounds and compositions useful for reducing or inhibiting tumor growth. It also relates to methods of use and the preparation of phenethyldihydrobenzodioxolone compounds.

Abstract: Novel forms of [R, (R*,R*)]-2-(4-Fluorophenyl)-?,?dihydroxy-5-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1-H-pyrrole-1-heptanoic acid hemi calcium salt designated Form XX, Form XXI, Form XXII, Form XXIII, Form XXIV, Forms XXV, Form XXVII, Form XXVIII, Form XXXIX, and Forms XXX, characterized by their X-ray powder diffractor, solid state NMR, and/or Raman spectroscopy are describes as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia (BPH) and Alzheimer) disease.

Abstract: A recliner mechanism for a seat. The recliner mechanism may include a first plate, a second plate, a set of pawls, and a driver. The driver may actuate the set of pawls when the driver rotates about the axis. A dump ramp protrusion may be provided to inhibit movement of the pawls from a refracted position to a locked position.

Abstract: This disclosure provides a multi-specific fusion protein composed of a CD86 antagonist binding domain and another binding domain that is an IL-10 agonist, an HLA-G agonist, an HGF agonist, an IL-35 agonist, a PD-1 agonist, a BTLA agonist, a LIGHT antagonist, a GITRL antagonist or a CD40 antagonist. The multi-specific fusion protein may also include an intervening domain that separates the other domains. This disclosure also provides polynucleotides encoding the multi-specific fusion proteins, compositions of the fusion proteins, and methods of using the multi-specific fusion proteins and compositions.

Abstract: The present disclosure concerns a spectrometer (10) and method for generating a two dimensional spectrum (S). The spectrometer (10) comprises a main grating (3) and cross dispersion element (2). An imaging mirror (4) is arranged for reflecting and focussing dispersed radiation (R3) from the main grating (3) towards an image plane (IP) for imaging the two dimensional spectrum (S) onto an image plane (IP) of the spectrometer (10). A correction lens (6) is arranged for correcting optical aberrations in the imaging of the two dimensional spectrum (S) in the image plane (IP). The imaging mirror (4) and correction lens (6) have a coinciding axis of cylindrical symmetry (AS).

Abstract: An end fitting (300), flexible pipe (100), riser (203), and method of producing the same are disclosed. A method of venting gas from annuli (312, 319) of a flexible pipe is also disclosed. The end fitting includes a first vent flow fluid communication path (311) and a further vent flow fluid communication path (318). The end fitting is capable of enabling gas to be vented from a flexible pipe body with two annulus regions (312, 319).

Abstract: Single chain fusion proteins that specifically bind to a TCR complex or a component thereof, such as TCR?, TCR?, or CD3?, along with compositions and methods of use thereof are provided.

Abstract: A method and system are provided for synchronizing local clocks more quickly in a telecommunication network using IEEE 1588. A network element that receives timing signals from one or more possible parent clocks considers a measure of the reliability of the timing signals contained in Announce messages from the parent clock or clocks. The clock uses this reliability information in selecting one of the possible parent clock or clocks to use as the actual parent clock. Once the selection is made, the clock adjusts the filtering characteristics applied to timing signals received from the selected parent clock. The adjustments reflect how confident the parent clock is as to how stable the timing information, it provides has become. If the indication of reliability contained in Announce messages received from the parent clock indicates that the timing information is not very reliable, then a high filter bandwidth is used in filtering the timing signals.

Abstract: The invention relates to operating a Machine-Type Communication (MTC) device for communication with a cellular radio network. A transmission is made from the MTC device to the cellular radio network to register the MTC device with the cellular radio network. The transmission includes a message from the MTC device to the cellular radio network, identifying the MTC device as an MTC device to the cellular radio network. Also, the MTC device has an associated HPLMN. An instruction is received at the MTC device from the network not to make a transmission from the MTC device for accessing the network. The instruction specifies a criteria for the MTC device's HPLMN or preferred list of networks. The MTC Device compares the criteria with the HPLMN associated with the MTC device and avoids making a transmission to access the network for a period of time based on the result comparing step.

Abstract: This disclosure provides a multi-specific fusion protein composed of a CD86 antagonist binding domain and another binding domain that is an IL-10 agonist, an HLA-G agonist, an HGF agonist, an IL-35 agonist, a PD-1 agonist, a BTLA agonist, a LIGHT antagonist, a GITRL antagonist or a CD40 antagonist. The multi-specific fusion protein may also include an intervening domain that separates the other domains. This disclosure also provides polynucleotides encoding the multi-specific fusion proteins, compositions of the fusion proteins, and methods of using the multi-specific fusion proteins and compositions.

Abstract: A flame arrestor including a flame arrestor collar and a flame arrestor plug. The flame arrestor collar includes a flame path that may be defined by one or more modules. The flame arrestor plug may be configured for connection to the flame arrestor collar. Various embodiments of a flame arrestor, including those having venting and/or draining elements or capabilities are also disclosed.

Abstract: The present application relates to overcoming some of the physical problems associated with putting a biometric sensor into the body of an electronic card, such as a smart card. A disclosed method of manufacturing an electronic card including a biometric sensor may include providing a preformed card body including a circuit having contacts for connection to a biometric sensor, the contacts being embedded within the preformed card body, removing material from the preformed card body to form a cavity in the preformed card body to expose the contacts, coating walls of the cavity with an adhesive epoxy, and connecting a biometric sensor to the contacts using an conductive epoxy. Also disclosed is an electronic card including a biometric sensor manufactured by this method.

Abstract: A method and system are provided for synchronizing local clocks more quickly in a telecommunication network using IEEE 1588. A network element that receives timing signals from one or more possible parent clocks considers a measure of the reliability of the timing signals contained in Announce messages from the parent clock or clocks. The clock uses this reliability information in selecting one of the possible parent clock or clocks to use as the actual parent clock. Once the selection is made, the clock adjusts the filtering characteristics applied to timing signals received from the selected parent clock. The adjustments reflect how confident the parent clock is as to how stable the timing information, it provides has become. If the indication of reliability contained in Announce messages received from the parent clock indicates that the timing information is not very reliable, then a high filter bandwidth is used in filtering the timing signals.

Abstract: Prodrugs of an NMDA antagonist, (S)-1-phenyl-2-(pyridin-2-yl)ethanamine, useful for the treatment of depression (particularly major depressive disorder) or pain; compositions comprising them, and methods of making them.

Abstract: A system, method, and computer-readable storage medium configured to facilitate user purpose in a computing architecture.

Abstract: The present disclosure concerns a monolithic spectrometer (1) for spectrally resolving light (R). The spectrometer (1) comprises a body (2) of solid material having optical surfaces (3, 4, 5, 6, 8) arranged to guide the light (R) along an optical path (E1, E2, E3, E4) inside the body (2). A collimating surface (4) and focusing surface (6) are part of a single surface having a continuous optically functional shape. The surfaces (3,4,5,6,8) of the body (2) are arranged to have a third or fourth part (E3, E4) of the optical path between a grating surface (5) and an exit surface (8) cross (C) with a first part (E1) of the optical path between an entry surface (3) and a collimating surface (4).