Abstract: A computer keyboard is refurbished by applying to its keys stickers each bearing a character designating the action of a respective key. For application of the stickers to the keys, the stickers are configured and arranged on an application tape in a layout congruent with the layout of the keys by a digital scan of the keyboard. The stickers are temporarily attached to the application tape by a peelable adhesive and then permanently attached to the keys by a pressure-sensitive permanent adhesive.

Abstract: A method of method of processing optical coherence tomography, OCT, image data representing an OCT image of a retina of an eye, to generate mapping data which maps out a predetermined band of a plurality of distinct bands which extend across the OCT image and correspond to respective anatomical layers of the retina. The method comprises: receiving the OCT image data; processing A-scan data of the received OCT image data to generate data indicative of sequences of A-scan elements corresponding to the predetermined band of the plurality of distinct bands and having respective A-scan element values that vary in accordance with a predetermined pattern; and generating the mapping data by applying a line-finding algorithm to determine a line passing through the sequences of A-scan elements indicated by the generated data.

Abstract: A method of determining a minimum wall thickness for a pipe joint for use in a subsea pipeline comprises the steps of: i) determining an internal diameter of the pipe joint; ii) determining a minimum allowable hydrostatic pressure at the depth at which the pipe joint is to be used; iii) determining a target wall thickness for the pipe joint, the target wall thickness corresponding to the internal diameter and the minimum allowable hydrostatic pressure; iv) manufacturing a plurality of preliminary pipe joints having the internal diameter and the target wall thickness; v) carrying out external pressure collapse tests resulting in data representative of the hydrostatic collapse pressures at which the plurality of preliminary pipe joints collapse; vi) determining a probability distribution corresponding to the data based on a statistical tail model derived from Extreme Value Theory; vii) determining from the probability distribution a hydrostatic collapse pressure occurring with a probability of 10?5 or lower; an

Abstract: High performance modules for use in System-in-Package (SIP) devices, and methods of manufacture for such modules and SIPs. The modules employ one or more interposer substrates on which high performance components and/or devices are operatively mounted and interconnected.

Abstract: A system includes at least partially autonomous vehicles, at least partially separated interconnected roadways, and a management system. Each of the vehicles is configured to cooperate with another vehicle or an area controller. The management system is configured to receive requests to transport, which may have respective start points and respective destinations. Additionally, the management system is configured, responsive to receiving the request, to assign a vehicle to fulfill the request. The assigned vehicle is configured to transport a person from the respective start point, at least in part via the interconnected roadways, to the respective destination.

Abstract: This disclosure relates to a striking tool for use in a high velocity, high impact energy comminution mill. The tool comprises an elongate body attachable at a first end to the comminution mill, and further comprises a wear resistant element for improving the wear resistance of the striking tool. The wear resistant element comprises a plurality of individual units.

Abstract: An apparatus for cleaning a surface, the apparatus including a body defining a chamber, an inlet for liquid flow into the chamber, an outlet for liquid flow from the chamber, a nozzle connected to the outlet for generating an output flow of liquid for cleaning a surface, an acoustic transducer associated with the body to introduce acoustic energy into the liquid within the chamber whereby the acoustic energy is present in the liquid flowing out of the nozzle, and a gas bubble generator for generating gas bubbles within the liquid flowing out of the nozzle.

Abstract: A reaction vessel comprises a lower chamber with a first volume, and an upper chamber with a second volume greater than the first volume. A thermocycling system for heating the reaction vessel includes a lower heating zone to heat the lower chamber, an upper heating zone to heat the upper chamber, and a lid heater to heat an opening of the upper chamber. A method comprises loading a sample into a lower chamber of a reaction vessel, thermocycling the lower chamber using a lower heating zone of the thermo cycler, combining an additive into the sample to produce a combination filling the lower chamber and at least partially filling an upper chamber of the reaction vessel, and incubating the upper and lower chambers using the lower heating zone and an upper heating zone. The lower and upper chambers can have different wall thicknesses to facilitate heat transfer.

Abstract: A method for analyzing an analog circuit controlled by a plurality of digital inputs is presented. The circuit is represented with a data structure with nodes connected via edges, which represent a circuit component. The data structure can be traversed across all connected nodes; and said digital inputs can be toggled between two or more input states. The method steps include identifying a set of boundary nodes in the data structure which are at a digital-analog boundary of the data structure; for each digital input, identifying associated boundary nodes which are coupled with the digital input; grouping digital inputs into input sets, where each of the different input sets are associated with mutually exclusive sets of associated boundary nodes, and analyzing the circuit by successively analyzing one or more of the input sets for all possible combinations of inputs states within that set.

Abstract: A system, method, and computer-readable storage medium configured to facilitate user purpose in a computing architecture.

Abstract: A power management device and microprocessor within a System-in-Package (SiP) are provided with communication signals externally available as outputs from the SiP so that they can be reconfigured by an external device. Methods for the configuration of SiPs and Power Management Integrated Circuits (PMICs) packaged within a SiP are also provided.

Abstract: The embodiments herein provide a secure computing resource set identification, evaluation, and management arrangement, employing in various embodiments some or all of the following highly reliable identity related means to establish, register, publish and securely employ user computing arrangement resources in satisfaction of user set target contextual purposes.

Abstract: Systems and methods of identifying reagents loaded into a fluid handling system can comprise programming a protocol for preparing a sample into a controller of the fluid handling system, loading multiple reagent vessels into a carousel of the fluid handling system, imaging individual labels of the multiple reagent vessels with an imaging device to produce label images, comparing information in the label images to identification information located in a database in communication with the controller, and determining if appropriate reagents have been loaded into the carousel to perform the protocol. A fluid handling system can include a deck, a tube holder, an imaging device, a pipettor, a non-transitory computer-readable storage medium and a processor configured to perform the method.

Abstract: The embodiments herein provide a secure computing resource set identification, evaluation, and management arrangement, employing in various embodiments some or all of the following highly reliable identity related means to establish, register, publish and securely employ user computing arrangement resources in satisfaction of user set target contextual purposes.

Abstract: Amino-pyrazinecarboxamide compounds, conjugates, and pharmaceutical compositions for use in the treatment of disease, such as cancer, are disclosed herein. The disclosed compounds are useful, among other things, in the treating of cancer and fibrosis and modulating TGF?R2. Additionally, compounds incorporated into a conjugate with an antibody construct are described herein.

Abstract: The present invention provides an article inverting and displacing apparatus and a machine for making sandwiches comprising the apparatus, wherein the apparatus comprises an engagement member (12) adapted to engage a lateral edge portion of a sandwich element; a drive unit (14) configured to drive the engagement member (12) to lift and turn the sandwich element engaged thereby about is opposite lateral edge to invert it; and a control unit configured to control the drive unit (14); wherein the control unit is configured to control the drive unit (14) to drive the engagement member (12) so that the opposite lateral edge of the sandwich element is caused to be raised to approximately at or above the level or height of the engaged lateral edge portion during the inverting step, and, optionally subsequently the sandwich element is caused to lie in a generally horizontal plane. The present invention also provides a process of automatically inverting and displacing articles.

Abstract: A server stores a set of laboratory applications to process batches of samples. The server receives, from a first lab administrator, a selection of a subset of the laboratory applications to process the batches of samples and an admin configuration for a laboratory application in the subset. The server receives configuration(s) of batch(es) to be used for running at least a portion of the subset of laboratory applications configured according to the admin configuration. The server receives, from a first scientific device, a request to run a laboratory application form the first subset to process a batch. The server provides the laboratory application(s) that are capable of being executed using the first scientific device. The server receives, from the first scientific device, a selected laboratory application. The server transmits, to the first scientific device, a signal for executing a first part of the selected laboratory application.

Abstract: The embodiments herein provide a secure computing resource set identification, evaluation, and management arrangement, employing in various embodiments some or all of the following highly reliable identity related means to establish, register, publish and securely employ user computing arrangement resources in satisfaction of user set target contextual purposes.

Abstract: A laboratory workstation for preparing a sample according to a programmed protocol. The laboratory workstation may include a display device configured to display an instruction for loading a first item of labware onto a deck of the laboratory workstation at a position on the deck specified by the programmed protocol; an imaging device configured to monitor the deck of the laboratory workstation by creating one or more images of the deck; and a processor configured to recognize, in the one or more images created by the imaging device, an item of labware loaded onto the deck by an operator. In some embodiments, the processor may be configured to indicate on the display device whether the recognized item of labware loaded by the operator is arranged on the deck in accordance with the programmed protocol.

Abstract: An apparatus for cleaning a surface includes a body defining a cavity and terminating in a distal end that is adapted, in use, to be in the vicinity of a surface to be cleaned such that the surface forms an end wall of a chamber including the cavity; at least one cleaning liquid inlet for flow of a cleaning liquid into the chamber; a divider located in or at the end of the cavity that divides the chamber into first and second portions, the second portion, in use, being in fluid communication with the surface to be cleaned; and an acoustic transducer associated with the first portion to introduce acoustic energy into the chamber; wherein the divider is adapted to permit the passage of acoustic energy therethrough from the first portion to the second portion of the chamber to thereby allow pressure fluctuations to be generated at the surface.