Abstract: A biological fluid filtration device, system, and method, for filtering a biological fluid, the device comprising a housing having an inlet, a first outlet and a second outlet, with a first fluid flow path defined between the inlet and the first outlet, with a second fluid flow path defined between the inlet and the second outlet, with a first biological fluid filtration media interposed between the inlet and the first outlet and across the first fluid flow path, with a second biological fluid filtration media interposed between the inlet and the second outlet and across the second fluid flow path, the housing essentially lacking a solid partition wall between the first biological fluid filtration media and the second biological fluid filtration media, a first flow restriction may be added downstream of the first biological fluid filtration media, and a second flow restriction may be added downstream of the second biological fluid filtration media, in another embodiment, the device comprises a housing having

Abstract: Biological fluid filtration systems including biological fluid filtration devices capable of filtering blood or blood products, including the removal of leukocytes from the blood or blood product. Each system includes a means to automatically drain the biological fluid upstream of the biological fluid filtration media disposed in the biological fluid filtration device. Both single sided and double sided biological fluid filtration devices are disclosed, including double sided biological fluid filtration devices with a solid partition wall with a first independent fluid flow path on one side of the partition wall, and a second independent fluid flow path on the other side of the partition wall. Draining means include vent filtration devices, diaphragm draining devices, and biological fluid filtration devices that include an integral diaphragm.

Abstract: A biological fluid filtration device, system, and method, for filtering a biological fluid, the device comprising a housing having an inlet, a first outlet and a second outlet, with a first fluid flow path defined between the inlet and the first outlet, with a second fluid flow path defined between the inlet and the second outlet, with a first biological fluid filtration media interposed between the inlet and the first outlet and across the first fluid flow path, with a second biological fluid filtration media interposed between the inlet and the second outlet and across the second fluid flow path, the housing essentially lacking a solid partition wall between the first biological fluid filtration media and the second biological fluid filtration media, a first flow restriction may be added downstream of the first biological fluid filtration media, and a second flow restriction may be added downstream of the second biological fluid filtration media, in another embodiment, the device comprises a housing having

Abstract: A flow diverter, vacuum control and tilting of the liquid filtering system are used alternatively or in conjunction to reduce foam production in a filtered liquid sample. A liquid filtering system includes an upper sample reservoir, a filter and a lower storage bottle. A vacuum is applied below the sample filter to draw sample liquid through the sample filter into the storage bottle. A flow diverter may be used to direct flow of the filtered liquid sample onto a sidewall of the storage bottle or guide flow to a bottom of the storage bottle. The vacuum may be regulated to reduce foaming. The liquid filtering system may be tilted to direct fluid to the sidewall of the lower storage bottle and reduce foaming.

Abstract: A liquid filtering system and methods for filtering are disclosed. One embodiment of the system includes a filtering apparatus having a receiving receptacle coupled with an adapter. The adapter has an adapter port for receiving a vacuum and an interface for coupling with an output receptacle that receives filtered liquid from the filtering apparatus. The adapter is between the receiving receptacle and output receptacle when the output receptacle is coupled with the adapter interface. The system also includes a base having a substantially rigid housing containing an internal vacuum channel terminating at a base vacuum delivery port. The adapter is couplable with the base to connect the adapter port to the base vacuum delivery port.

Abstract: Biological fluid filtration systems including biological fluid filtration devices capable of filtering blood or blood products, including the removal of leukocytes from the blood or blood product. Each system includes a mechanism to automatically drain the biological fluid upstream of the biological fluid filtration media disposed in the biological fluid filtration device. Both single sided and double sided biological fluid filtration devices are disclosed, including double sided biological fluid filtration devices with a solid partition wall with a first independent fluid flow path on one side of the partition wall, and a second independent fluid flow path on the other side of the partition wall. Draining mechanisms include vent filtration devices, diaphragm draining devices, and biological fluid filtration devices that include an integral diaphragm.

Abstract: Biological fluid filtration systems including biological fluid filtration devices capable of filtering blood or blood products, including the removal of leukocytes from the blood or blood product. Each system includes a means to automatically drain the biological fluid upstream of the biological fluid filtration media disposed in the biological fluid filtration device. Both single sided and double sided biological fluid filtration devices are disclosed, including double sided biological fluid filtration devices with a solid partition wall with a first independent fluid flow path on one side of the partition wall, and a second independent fluid flow path on the other side of the partition wall. Draining means include vent filtration devices, diaphragm draining devices, and biological fluid filtration devices that include an integral diaphragm.

Abstract: A liquid filtering system and methods for filtering are disclosed. One embodiment of the system includes a filtering apparatus having a receiving receptacle coupled with an adapter. The adapter has an adapter port for receiving a vacuum and an interface for coupling with an output receptacle that receives filtered liquid from the filtering apparatus. The adapter is between the receiving receptacle and output receptacle when the output receptacle is coupled with the adapter interface. The system also includes a base having a substantially rigid housing containing an internal vacuum channel terminating at a base vacuum delivery port. The adapter is couplable with the base to connect the adapter port to the base vacuum delivery port.

Abstract: A filtration funnel with integral prefilter usable for filtering fluids. The integral prefilter is disposed above the final filter which is sealed to the funnel. The prefilter may contain one or more layers of prefilter material, and is sealed to the funnel with one or more seal rings. The funnel may be used with either vacuum or pressure.

Abstract: A vacuum filtration apparatus for detecting microorganisms and particulates in liquid samples. The apparatus includes a base, an absorbent pad, a filter means, a funnel and a lid. The funnel is releasably attached to the base, and may contain an integral flexible seal for releasably sealing the filter means to the base. The outer wall of the lid may be segmented to make it flexible, this flexibility allows it to be releasably attached to the funnel or the base. The apparatus is designed so that any funnel will fit any base, and any lid will fit any base or any funnel when all parts are manufactured to normal tolerances. The apparatus may contain a means to keep the filter means wrinkle free in both the dry and wet states.

Abstract: A vacuum filtration apparatus (900) for detecting microorganisms and particulates in liquid samples. The apparatus includes a base (901), an absorbent pad (991), a filter (990), a funnel (930), and a lid (960). The funnel is releasably attached to the base, and may contain an integral flexible seal for releasably sealing the filter to the base. The outer wall of the lid may be segmented to make it flexible, this flexibility allows it to be releasably attached to the funnel or the base. The apparatus is designed so that any funnel will fit any base, and any lid will fit any base or any funnel when all parts are manufactured to normal tolerances. The apparatus may be configured to keep the filter wrinkle free in both the dry and wet states.

Abstract: A flow diverter, vacuum control and tilting of the liquid filtering system are used alternatively or in conjunction to reduce foam production in a filtered liquid sample. A liquid filtering system includes an upper sample reservoir, a filter and a lower storage bottle. A vacuum is applied below the sample filter to draw sample liquid through the sample filter into the storage bottle. A flow diverter may be used to direct flow of the filtered liquid sample onto a sidewall of the storage bottle or guide flow to a bottom of the storage bottle. The vacuum may be regulated to reduce foaming. The liquid filtering system may be tilted to direct fluid to the sidewall of the lower storage bottle and reduce foaming.

Abstract: A high capacity gravity feed filter for filtering blood and blood products or the like includes a body having an inlet port, an outlet port, two filter wells, at least one filter element disposed in each of said filter wells, between the inlet port and outlet port so as to filter liquid which flows into the filtration device via the inlet port. The filter elements divide each of said filter wells into a first chamber and a second chamber. The device allows gases to vent the filtration device through the outlet port. The means may include a through slot located at the top of each of said second chambers. The filtration device allows air therein to be purged downstream into a receiving blood bag without the manipulation of the height of the filtration device or the receiving blood bag.

Abstract: A filtration funnel with integral prefilter usable for filtering fluids. The integral prefilter is disposed above the final filter which is sealed to the funnel. The prefilter may contain one or more layers of prefilter material, and is sealed to the funnel with one or more seal rings. The funnel may be used with either vacuum or pressure.

Abstract: An apparatus and method for mixing a solvent with a solute to form a solution, and for separating said solution from excess solute so that a sample of solution less excess solute can be obtained, and for synthesizing drug compounds.

Abstract: A vacuum filtration apparatus (900) for detecting microorganisms and particulates in liquid samples. The apparatus includes a base (901), an absorbent pad (991), a filter (990), a funnel (930), and a lid (960). The funnel is releasably attached to the base, and may contain an integral flexible seal for releasably sealing the filter to the base. The outer wall of the lid may be segmented to make it flexible, this flexibility allows it to be releasably attached to the funnel or the base. The apparatus is designed so that any funnel will fit any base, and any lid will fit any base or any funnel when all parts are manufactured to normal tolerances. The apparatus may be configured to to keep the filter wrinkle free in both the dry and wet states.

Abstract: A high capacity gravity feed filter for filtering blood and blood products or the like includes a body having an inlet port, an outlet port, two filter wells, at least one filter element disposed in each of said filter wells, between the inlet port and outlet port so as to filter liquid which flows into the filtration device via the inlet port. The filter elements divide each of said filter wells into a first chamber and a second chamber. The device allows gases to vent the filtration device through the outlet port. The means may include a vertical channel within each of said second chambers. The filtration device allows air therein to be purged downstream into a receiving blood bag without the manipulation of the height of the filtration device or the receiving blood bag.

Abstract: An apparatus for mixing a solvent with a solute to form a solution, and for separating said solution from excess solute so that a sample of solution less excess solute can be obtained, and for synthesizing drug compounds.

Abstract: A filtration device for separating filtrate and concentrate from a solution that contains a dead stop feature. The dead stop volume is determined by the location of an outlet port. The apparatus includes a housing with a means for collecting filtrate and a filter unit insertable within the housing. The filter unit contains a semipermeable membrane thereon for separating filtrate from concentrate.

Abstract: An in-line liquid filtration device useable for filtration of blood, blood products or the like includes a housing having an inlet port, an outlet port, at least one filter element disposed in the housing between the inlet port and outlet port so as to filter liquid which flows into the filtration device via the inlet port. The filter element divides the housing into a first chamber and a second chamber. The device allows gases to vent the filtration device through the outlet port. The means may include a flow deflector within the first chamber and/or the second chamber. The means may also include a channel, preferably spiral, within either the first chamber and/or second chamber. The filtration device allows air therein to be purged downstream into either an air collecting bag or into the blood receiving bag without the manipulation of the height of the filtration device or the blood receiving bag.