Patents by Inventor Philip A. Jones

Philip A. Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF METALLO-BETA-LACTAMASES
    Publication number: 20200375946
    Abstract: The present invention relates to certain compounds, in particular, indole derivatives that function as inhibitors of bacterial metallo-beta-lactamases. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of a bacterial infection.
    Type: Application
    Filed: November 30, 2016
    Publication date: December 3, 2020
    Inventors: Jürgen Brem, Anna M. Rydzik, Michael A. McDonough, Christopher J. Schofield, Angus Morrison, Joanne Hewitt, Andrew Pannifer, Philip Jones
  • Heterocyclic inhibitors of PTPN11
    Patent number: 10851110
    Abstract: The present invention relates to compounds which may be useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: December 1, 2020
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Philip Jones, Barbara Czako, Jason Cross, Paul Leonard, Faika Mseeh, Connor Austin Parker
  • HETEROCYCLIC INHIBITORS OF TYROSINE KINASE
    Publication number: 20200354343
    Abstract: The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of HER2 or EGFR for the treatment or prevention of disease, including cancer.
    Type: Application
    Filed: April 24, 2020
    Publication date: November 12, 2020
    Inventors: John HEYMACH, Jacqulyne ROBICHAUX, Monique NILSSON, Philip JONES, Jason CROSS, Jay THEROFF
  • Modifying virtual reality boundaries based on usage
    Patent number: 10832477
    Abstract: A method and system for modifying virtual reality (VR) boundaries based on usage includes defining, using a virtual reality system including a computer communicating with head set, a safe area defining a geographic location for a user. The safe area is monitored for when the user strays into a second area beyond the safe area. The second area is defined in relation to the safe area that the user strayed into beyond the safe area. The user interaction in the second area beyond the safe area for safety is assessed, and a determination is made when the second area is safe based on a criteria. In response to the determining that the second area is safe, not initiating an alert to the user of being outside the safe area.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: November 10, 2020
    Assignee: International Business Machines Corporation
    Inventors: Matthew Bailey, Andrew Daniel, Philip Jones, Richard Pilot
  • Heterocyclic inhibitors of ATR kinase
    Patent number: 10800774
    Abstract: The present invention relates to heterocyclic compounds and methods which may be useful as inhibitors of ATR kinase for the treatment or prevention of cancer.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: October 13, 2020
    Assignees: Board of Regents, The University of Texas System, ChemPartner Corporation
    Inventors: Maria Emilia Di Francesco, Philip Jones, Christopher Lawrence Carroll, Jason Bryant Cross, Zhijun Kang, Michael Garrett Johnson, Sarah Lively
  • Heterocyclic inhibitors of ATR kinase
    Patent number: 10800769
    Abstract: The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of ATR kinase for the treatment or prevention of cancer.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: October 13, 2020
    Assignees: Board of Regents, The University of Texas System, ChemPartner Corporation
    Inventors: Maria Emilia Di Francesco, Philip Jones, Christopher Lawrence Carroll, Jason Bryant Cross, Suyambu Kesava Vijayan Ramaswamy, Michael Garrett Johnson, Sarah Lively, David Lapointe
  • GLS1 inhibitors for treating disease
    Patent number: 10766892
    Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: September 8, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Maria Emilia Di Francesco, Philip Jones, Timothy Heffernan, Matthew M. Hamilton, Zhijun Kang, Michael J. Soth, Jason P. Burke, Kang Le, Christopher Lawrence Carroll, Wylie S. Palmer, Richard Lewis, Timothy McAfoos, Barbara Czako, Gang Liu, Jay Theroff, Zachary Herrera, Anne Yau
  • Tetrahydropyrido[4,3-d]pyrimidine inhibitors of ATR kinase
    Patent number: 10745420
    Abstract: The present invention relates to tetrahydropyrido[4,3-d]pyrimidine based compounds and methods which may be useful as inhibitors of ATR kinase for the treatment or prevention of cancer.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: August 18, 2020
    Assignees: Board of Regents, The University of Texas System, ChemPartner Corporation
    Inventors: Maria Emilia Di Francesco, Philip Jones, Christopher Lawrence Carroll, Jason Bryant Cross, Michael Garrett Johnson, Sarah Lively
  • GLS1 inhibitors for treating disease
    Patent number: 10738043
    Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: August 11, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Richard Thomas Lewis, Philip Jones, Alessia Petrocchi, Naphtali Reyna, Matthew Hamilton, Michael J. Soth, Timothy Heffernan, Michelle Han, Jason P. Burke
  • Video stream augmenting
    Patent number: 10701444
    Abstract: Augmenting a video stream of an environment is provided, the environment containing a private entity to be augmented. Video of the environment is processed in accordance with an entity recognition process to identify the presence of at least part of an entity in the environment. It is determined whether the identified entity is to be augmented based on information relating to the identified entity and the private entity. Based on determining that the identified entity is to be augmented, the video stream is modified to replace at least a portion of the identified entity with a graphical element adapted to obscure the portion of the identified entity in the video stream. By modifying the video stream to obscure an entity, private or personal information in the environment may be prevented from being displayed to a viewer of the video stream.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: June 30, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Matthew C. Bailey, Andrew J. Daniel, Philip Jones, Richard W. Pilot
  • Method and system for displaying a virtual item in an augmented reality environment
    Patent number: 10699489
    Abstract: A method for displaying a virtual item, generated by a user, in a physical space shared with other users, in an augmented reality environment, comprising of forming segments in the physical space, designating a designated interaction type of the segment for placing the virtual item, placing the virtual item, generated by the user, into the segment based on a comparison between the interaction type of the virtual item and the designated interaction type of the segment, and updating a user-accessible repository comprising information on the interaction type of a virtual item and the segment the virtual item is placed in.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: June 30, 2020
    Assignee: International Business Machines Corporation
    Inventors: Richard Pilot, Philip Jones, Matthew Bailey, Andrew J. Daniel
  • COMPOSITIONS AND METHODS FOR TREATING WATER
    Publication number: 20200189934
    Abstract: Methods of treating water to promote the health of aquatic organisms are described. The method may include introducing pulverized kaolin into the water. The pulverized kaolin may have a particle size distribution such that at least 30% by weight of the particles pass through a 60 mesh screen. For example, the pulverized kaolin may be in the form of a dry powder having a d50 diameter less than 300 ?m. The pulverized kaolin may remain dispersed or suspended in the water without dispersants and/or surfactants, e.g., to reduce the amount of at least one pathogenic microorganism present in the water and/or to reduce or prevent exposure of aquatic organisms to the pathogenic microorganism(s).
    Type: Application
    Filed: March 16, 2018
    Publication date: June 18, 2020
    Inventors: Peter BIZA, Philip JONES, David CUMMINGS, Anthony LYONS, Christopher BOOTHBY, Marc DE SAILLY
  • SALTS OF HETEROCYCLIC MODULATORS OF HIF ACTIVITY FOR TREATMENT OF DISEASE
    Publication number: 20200171017
    Abstract: The present disclosure relates to salts of heterocyclic compounds and methods that inhibit HIF pathway activity. The compounds are designed to treat or prevent cancer and other hypoxia-mediated diseases.
    Type: Application
    Filed: June 24, 2019
    Publication date: June 4, 2020
    Inventors: Philip JONES, Maria Emilia DI FRANCESCO, Timothy MCAFOOS
  • HETEROCYCLIC INHIBITORS OF ATR KINASE
    Publication number: 20200102296
    Abstract: The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of ATR kinase for the treatment or prevention of cancer.
    Type: Application
    Filed: July 10, 2019
    Publication date: April 2, 2020
    Inventors: Maria Emilia DI FRANCESCO, Philip JONES, Christopher Lawrence CARROLL, Jason Bryant CROSS, Suyambu Kesava Vijayan RAMASWAMY, Michael Garrett JOHNSON, Sarah LIVELY, David LAPOINTE
  • METHOD AND SYSTEM FOR DISPLAYING A VIRTUAL ITEM IN AN AUGMENTED REALITY ENVIRONMENT
    Publication number: 20200105060
    Abstract: A method for displaying a virtual item, generated by a user, in a physical space shared with other users, in an augmented reality environment, comprising of forming segments in the physical space, designating a designated interaction type of the segment for placing the virtual item, placing the virtual item, generated by the user, into the segment based on a comparison between the interaction type of the virtual item and the designated interaction type of the segment, and updating a user-accessible repository comprising information on the interaction type of a virtual item and the segment the virtual item is placed in.
    Type: Application
    Filed: October 2, 2018
    Publication date: April 2, 2020
    Inventors: Richard Pilot, Philip Jones, Matthew Bailey, Andrew J. Daniel
  • COMPOSITIONS COMPRISING INTERCALATED MATERIALS AND METHODS OF USE THEREOF
    Publication number: 20200071238
    Abstract: Compositions of clay materials intercalated with urea and/or another material or combination of materials are discussed. For example, the composition may comprise from about 20% to about 65% by weight intercalated urea, with respect to the total weight of the composition. Intercalation may be achieved, for example, by grinding the clay particles with one or more other materials, such that the other material(s) are intercalated into the clay particles. The composition may be formed into pills formulated for controlled release of urea, e.g., for fertilizing soil.
    Type: Application
    Filed: February 28, 2018
    Publication date: March 5, 2020
    Inventors: David CUMMINGS, Anthony LYONS, Christopher BOOTHBY, Philip JONES
  • PTPN11 INHIBITORS
    Publication number: 20200048249
    Abstract: The present invention relates to compounds which are useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.
    Type: Application
    Filed: August 9, 2019
    Publication date: February 13, 2020
    Inventors: Philip JONES, Barbara CZAKO, Christopher L. CARROLL, Pijus MANDAL, Jason CROSS
  • COMPOUNDS USEFUL AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN DIOXYGENASE
    Publication number: 20200024236
    Abstract: The present invention relates to bicyclic compounds and compositions and methods which may be useful as inhibitors of IDO1, IDO2, and TDO for the treatment or prevention of diseases such as cancer.
    Type: Application
    Filed: July 17, 2019
    Publication date: January 23, 2020
    Inventors: Richard T. LEWIS, Matthew HAMILTON, Philip JONES, Alessia PETROCCHI, Naphtali REYNA, Timothy MCAFOOS, Jason Bryant CROSS, Michael J. SOTH
  • WATERBORNE COMPOSITIONS CONTAINING ORGANIC ION-EXCHANGERS TO IMPROVE CORROSION RESISTANCE
    Publication number: 20190390065
    Abstract: The present invention provides an anti-corrosion composition comprising an organic ion-exchanger; and a waterborne resin, wherein a substrate exposed to a halide-containing environment and having the anti-corrosion composition applied thereto has a reduced level of corrosion compared to the substrate exposed to the halide-containing environment without the anti-corrosion composition being applied. The inventive waterborne anti-corrosion composition may find use on substrates such as automotive vehicles, bridges, cranes, superstructures, offshore oil & gas rigs, pipes, tanks, ships, barges, boats, aircraft, concrete, and masonry that are exposed to halide-containing environments.
    Type: Application
    Filed: June 22, 2018
    Publication date: December 26, 2019
    Inventors: Makoto NAKAO, Philip JONES, Carol KNOX, Ilya Ilyin, Boris Tkachev
  • SOLVENTBORNE COMPOSITIONS CONTAINING INORGANIC ION-EXCHANGERS TO IMPROVE CORROSION RESISTANCE
    Publication number: 20190390064
    Abstract: The present invention provides an anti-corrosion composition comprising an inorganic ion-exchanger and a solventborne resin, wherein a substrate exposed to a halide-containing environment and having the anti-corrosion composition applied thereto has a reduced level of corrosion compared to the substrate exposed to the halide-containing environment without the anti-corrosion composition being applied. The inventive solventborne anti-corrosion composition may find use on substrates such as automotive vehicles, bridges, cranes, superstructures, offshore oil & gas rigs, pipes, tanks, ships, barges, boats, aircraft, concrete, and masonry that are exposed to halide-containing environments.
    Type: Application
    Filed: June 22, 2018
    Publication date: December 26, 2019
    Inventors: Makoto NAKAO, Philip JONES, Carol KNOX, Ilya Ilyin, Boris Tkachev