Patents by Inventor Philip A. Jones

Philip A. Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10363248
    Abstract: The present disclosure relates to salts of heterocyclic compounds and methods that inhibit HIF pathway activity. The compounds are designed to treat or prevent cancer and other hypoxia-mediated diseases.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: July 30, 2019
    Assignee: Board of Regents, The University of Texas System
    Inventors: Philip Jones, Maria Emilia Di Francesco, Timothy McAfoos
  • Patent number: 10344025
    Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: July 9, 2019
    Assignee: Board of Regents, The University of Texas System
    Inventors: Maria Emilia Di Francesco, Philip Jones, Timothy Heffernan, Matthew M. Hamilton, Zhijun Kang, Michael J. Soth, Jason P. Burke, Kang Le, Christopher Lawrence Carroll, Wylie S. Palmer, Richard Lewis, Timothy McAfoos, Barbara Czako, Gang Liu, Jay Theroff, Zachary Herrera, Anne Yau
  • Publication number: 20190202569
    Abstract: A disconnect assembly configured to disconnect a parachute of an aerial delivery apparatus from a payload includes a detector device, a disconnect device, and a transmit cable. The detector device is configured to detect that the aerial delivery apparatus has landed, the disconnect device is configured to provide a releasable connection between the parachute and the payload, and the transmit cable is configured to transmit a mechanical trigger force from the detector device to the disconnect device. When the detector device detects that the aerial delivery apparatus has landed, the transmit cable transmits a mechanical trigger force from the detector device to the disconnect device and the disconnect device releases the connection between the parachute and the payload.
    Type: Application
    Filed: March 27, 2018
    Publication date: July 4, 2019
    Inventors: Martyn Philip JONES, Richard Anthony LAWS
  • Publication number: 20190204925
    Abstract: An acoustic field may be produced from a transducer array having known relative positions and orientations in this acoustic field, one or more control points may be defined. An amplitude may be assigned to the control point. Mid-air haptic effect for a virtual object on a human body part may be generated by moving the control point in a single closed curve comprising a plurality of curve segments. The single closed curve traverses at least one location where the human body part intersects with the virtual object. Additionally, a user may interact with virtual three-dimensional content using the user's hands while a tracking system monitoring the user's hands, a physics engine updates the properties of the virtual three-dimensional content and a haptic feedback system provides haptic information to the user.
    Type: Application
    Filed: March 7, 2019
    Publication date: July 4, 2019
    Inventors: Benjamin John Oliver Long, Philip Jones
  • Patent number: 10336968
    Abstract: Storage-stable compositions comprising soil release polymers. Compositions are described comprising A) of from 45 to 55% by weight of one or more polyesters according to the following formula (I) wherein R and R2 independently of one another are X—(OC2H4) n—(OC3H6)m wherein X is C1-4alkyl, the —(OC2H4) groups and the —(OC3H6) groups are arranged block-wise and the block consisting of the —(OC3H6) groups is bound to a COO group or are HO—(C3H6) n is based on a molar average a number of from 12 to 120, m is based on a molar average a number of from 1 to 10, and a is based on a molar average a number of from 4 to 9, and B) of from 10 to 30% by weight of one or more alcohols selected from the group consisting of ethylene glycol, 1,2-propylene glycol, 1,3 -propylene glycol, 1,2 -butylene glycol, 1,3 -butylene glycol, 1,4 -butylene glycol and butyl glycol and C) of from 24 to 42% by weight of water, the amounts in each case being based on the total weight of the composition.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: July 2, 2019
    Assignee: Conopco, Inc.
    Inventors: Robert John Carswell, Carsten Cohrs, Richard Michael Craven, David Philip Jones, Peter Eugen Klug, Helen Elspeth Lyon, Peter Helmut Erich Naumann, Alyn James Parry, Henricus Wilhelmus Ida Peerlings, Alastair Richard Sanderson, Andrew Wynne
  • Patent number: 10331522
    Abstract: A facility for event failure management is provided, which includes providing a failed event database containing failed event information relating to failed events and one or more components associated with each of the failed events. Upon modification to a component associated with a failed event, the failed event is retried. Based on a result of retrying the failed event, failed event information of the failed event database is updated. The failed event database may therefore be dynamically and/or automatically updated so that it contains up-to-date and appropriate information for predicting and/or managing event failures.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: June 25, 2019
    Assignee: International Business Machines Corporation
    Inventors: Mark Allman, Andrew S. Edwards, Philip Jones, Doina L. Klinger, Martin A. Ross, Paul S. Thorpe
  • Publication number: 20190164343
    Abstract: A method and system for modifying virtual reality (VR) boundaries based on usage includes defining, using a virtual reality system including a computer communicating with head set, a safe area defining a geographic location for a user. The safe area is monitored for when the user strays into a second area beyond the safe area. The second area is defined in relation to the safe area that the user strayed into beyond the safe area. The user interaction in the second area beyond the safe area for safety is assessed, and a determination is made when the second area is safe based on a criteria. In response to the determining that the second area is safe, not initiating an alert to the user of being outside the safe area.
    Type: Application
    Filed: November 30, 2017
    Publication date: May 30, 2019
    Inventors: Matthew Bailey, Andrew Daniel, Philip Jones, Richard Pilot
  • Patent number: 10306315
    Abstract: Augmenting a video stream of an environment is provided, the environment containing a private entity to be augmented. Video of the environment is processed in accordance with an entity recognition process to identify the presence of at least part of an entity in the environment. It is determined whether the identified entity is to be augmented based on information relating to the identified entity and the private entity. Based on determining that the identified entity is to be augmented, the video stream is modified to replace at least a portion of the identified entity with a graphical element adapted to obscure the portion of the identified entity in the video stream. By modifying the video stream to obscure an entity, private or personal information in the environment may be prevented from being displayed to a viewer of the video stream.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: May 28, 2019
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Matthew C. Bailey, Andrew J. Daniel, Philip Jones, Richard W. Pilot
  • Publication number: 20190144425
    Abstract: Disclosed herein is the compound (R)-1-(4-(6-(2-(4-(3,3-difluorocyclobutoxy)-6-methylpyridin-2-yl)acetamido)pyridazin-3-yl)-2-fluorobutyl)-N-methyl-1H-1,2,3-triazole-4-carboxamide, and salt forms and polymorphs thereof demonstrating improved exposure after oral dosing. Methods of inhibition GLS1 activity in a human or animal subject are also provided.
    Type: Application
    Filed: January 7, 2019
    Publication date: May 16, 2019
    Inventors: Philip JONES, Michael J. SOTH, Jason P. BURKE, Kang LE, Gang LIU
  • Publication number: 20190135793
    Abstract: The present invention relates to compounds and methods useful as inhibitors of KDM5 for the treatment or prevention of cancer.
    Type: Application
    Filed: May 17, 2018
    Publication date: May 9, 2019
    Inventors: Alessia PETROCCHI, Maria Emilia DI FRANCESCO, Philip JONES, Richard Thomas LEWIS, Naphtali REYNA, Matthew HAMILTON, Michelle HAN
  • Patent number: 10280171
    Abstract: The present invention relates to compounds which may be useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: May 7, 2019
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Philip Jones, Barbara Czako, Jason Cross, Paul Leonard, Faika Mseeh, Connor Austin Parker
  • Patent number: 10268275
    Abstract: An acoustic field may be produced from a transducer array having known relative positions and orientations In this acoustic field, one or more control points may be defined. An amplitude may be assigned to the control point. Mid-air haptic effect for a virtual object on a human body part may be generated by moving the control point in a single closed curve comprising a plurality of curve segments. The single closed curve traverses at least one location where the human body part intersects with the virtual object. Additionally, a user may interact with virtual three-dimensional content using the user's hands while a tracking system monitoring the user's hands, a physics engine updates the properties of the virtual three-dimensional content and a haptic feedback system provides haptic information to the user.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: April 23, 2019
    Assignee: Ultrahaptics IP Ltd
    Inventors: Thomas Andrew Carter, Adam Daniel Harwood, Benjamin John Oliver Long, Philip Jones
  • Publication number: 20190092764
    Abstract: Disclosed herein are compounds which inhibit the kinase activity of dual leucine zipper (DLK) kinase (MAP3K12), pharmaceutical compositions, and methods of treatment of DLK-mediated diseases, such as neurological diseases that result from traumatic injury to central nervous system and peripheral nervous system neurons (e.g. stroke, traumatic brain injury, spinal cord injury), or that result from a chronic neurodegenerative condition (e.g. Alzheimer's disease, frontotemporal dementia, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, spinocerebellar ataxia, progressive supranuclear palsy, Lewy body disease, Kennedy's disease, and other related conditions), from neuropathies resulting from neurological damage (chemotherapy-induced peripheral neuropathy, diabetic neuropathy, and related conditions) and from cognitive disorders caused by pharmacological intervention (e.g. chemotherapy induced cognitive disorder, also known as chemobrain).
    Type: Application
    Filed: September 4, 2018
    Publication date: March 28, 2019
    Inventors: Michael J. SOTH, Gang LIU, Kang LE, Jason CROSS, Philip JONES
  • Publication number: 20190055240
    Abstract: The present invention relates to heterocyclic compounds and methods which may be useful as inhibitors of ATR kinase for the treatment or prevention of cancer.
    Type: Application
    Filed: August 17, 2018
    Publication date: February 21, 2019
    Inventors: Maria Emilia DI FRANCESCO, Philip JONES, Christopher Lawrence CARROLL, Jason Bryant CROSS, Zhijun KANG, Michael Garrett JOHNSON, Sarah LIVELY
  • Patent number: 10208059
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: February 19, 2019
    Assignee: Board of Regents, The University of Texas System
    Inventors: Philip Jones, Maria Emilia Di Francesco, Alessia Petrocchi, Christopher L. Carroll, Joe Marszalek, Barbara Czako, Ryan Johnson, Jay Theroff
  • Publication number: 20190040129
    Abstract: The invention relates to an antigen binding site for binding to a P2X7 receptor, the antigen binding site being defined by general formula 1: FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4
    Type: Application
    Filed: July 11, 2018
    Publication date: February 7, 2019
    Inventors: Julian Alexander Barden, Neil Brewis, Philip Jones, Steven Grant
  • Publication number: 20190040291
    Abstract: The present invention provides an aqueous polyurethane dispersion (PUD) comprising an amorphous polyester having a glass transition temperature (Tg) as determined by differential scanning calorimetry of less than ?30° C.; wherein the aqueous polyurethane dispersion (PUD) has a glass transition temperature (Tg) as determined by differential scanning calorimetry (DSC) of 0° C. to 20° C. and a hard block content of greater than 50%.
    Type: Application
    Filed: April 9, 2018
    Publication date: February 7, 2019
    Inventors: Stephanie Goldfein, Makoto Nakao, Lyubov Gindin, Hans Georg Grablowitz, Ronald Konitsney, Derick Henderson, Tina Kasardo, Philip Jones, Michael K. Jeffries
  • Publication number: 20190031651
    Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.
    Type: Application
    Filed: October 5, 2018
    Publication date: January 31, 2019
    Inventors: Richard Thomas LEWIS, Philip JONES, Alessia PETROCCHI, Naphtali REYNA, Matthew HAMILTON, Michael J. SOTH, Timothy HEFFERNAN, Michelle HAN, Jason P. BURKE
  • Publication number: 20190016713
    Abstract: The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of ATR kinase for the treatment or prevention of cancer.
    Type: Application
    Filed: July 13, 2018
    Publication date: January 17, 2019
    Inventors: Maria Emilia DI FRANCESCO, Philip JONES, Christopher Lawrence CARROLL, Jason Bryant CROSS, Suyambu Kesava Vijayan RAMASWAMY, Michael Garrett JOHNSON, Sarah LIVELY, David LAPOINTE
  • Publication number: 20180370990
    Abstract: The present invention relates to tetrahydropyrido[4,3-d]pyrimidine based compounds and methods which may be useful as inhibitors of ATR kinase for the treatment or prevention of cancer.
    Type: Application
    Filed: May 25, 2018
    Publication date: December 27, 2018
    Inventors: Maria Emilia DI FRANCESCO, Philip JONES, Christopher Lawrence CARROLL, Jason Bryant CROSS, Michael Garrett JOHNSON, Sarah LIVELY