Abstract: The present invention relates to pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula III: wherein the variables are as defined herein.

Abstract: Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system configured for placement within the porous scaffold, and a seal configured to enclose a proximal opening in the porous scaffold. The device may further comprise a cell delivery device for delivering cells into the porous scaffold. The method of cell transplantation comprises a two step process. The device is incubated in the host body to form a vascularized collagen matrix around a plug positioned within the porous scaffold. The plug is then retracted from the porous scaffold, and cells are delivered into the vascularized space created within the porous scaffold.

Abstract: A method of preparing a cryo-surgical system for treatment includes accessing a container containing a refrigerant, a delivery tube having a first end configured to be in flow communication with the container and a second end opposite the first end. The system further includes a plurality of flexible finger portions disposed proximate the second end of the delivery tube opposite the first end. A porous applicator bud is disposed proximate the second end of the delivery tube. The porous applicator bud includes a body portion disposed between the plurality of flexible finger portions and a contact surface extending from the plurality of flexible finger portions. An adjustment ring disposed along the delivery tube adjacent to the plurality of flexible finger portions can be used to adjust the size of the contact surface of the porous applicator bud.

Abstract: A traction battery includes a housing that has a tray and a cover, and a plurality of battery components supported by the tray and enclosed by the cover. A service disconnect base is disposed within the housing and is electrically connected with the components by a circuit. The housing includes an access panel with a service disconnect plug attached to the panel. The access panel is movable between open and closed positions. The service disconnect plug connects circuitry within the service disconnect base when the panel is in the closed position. The service disconnect plug is disconnected with the service disconnect base when the panel is in the open position to open the circuit.

Abstract: An example battery cell for an electric vehicle includes at least one conductive case, and an electrode structure in direct electrical contact with the at least one conductive case. The electrode structure is to selectively provide power to an electric vehicle.

Abstract: An example contactor weld detection method for an electric vehicle includes detecting that a contactor is welded closed when the contactor is commanded closed.

Abstract: Disclosed is an apparatus, system, and method to utilize a plurality of road markers to aid a vehicle in merging into a lane. The lane that the merging vehicle desires to merge into is determined. Further, the position of the merging vehicle is determined. Target vehicles are then notified about the merging vehicle utilizing the plurality of road markers.

Abstract: A structure comprises an elongate, resiliently deformable cable, a body section comprising a cable-receiving aperture, said aperture being dimensioned so as to retain a length of said cable within it in use while permitting relative movement of said cable relative to the aperture in a direction along the length of the cable upon application of a set manipulating force, and retaining means for retaining the cable at a set position relative to the body section absent application of said force, wherein the cable at least partially defines the shape of the structure, and said shape may be changed by application of said manipulating force thus causing relative movement between the cable and the body section in a direction along the length of the cable.

Abstract: The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula V: wherein the variables are as defined herein.

Abstract: An integrated cell separator/high voltage bus bar carrier assembly for a high voltage traction battery includes a cell separator having a plurality of cell separator walls and a plurality of bus bar retention walls carried by the plurality of cell separator walls. A high voltage bus bar is carried by the plurality of bus bar retention walls of the cell separator.

Abstract: A rotor assembly that includes at least one integral non-magnetic rotor retaining structure comprising a plurality of individual rotor retaining discs, the discs having predefined slots; and a plurality of magnetic segments retained within the slots of the discs of the respective integral non-magnetic rotor retaining structure.

Abstract: A battery discharge device according to an exemplary aspect of the present disclosure includes, among other things, a sensor configured to sense a parameter of a high voltage source, a controller in communication with the sensor and a discharge circuit that discharges energy stored on the high voltage source in response to a command signal from the controller. The discharge circuit includes a plurality of resistors connected in parallel to one another.

Abstract: Disclosed is a method for securely presenting content in a mobile station. The mobile station may have a smart module, a security agent, and an air interface for communicating with a content provider and with a remote content rights manager. The smart module stores content presentation units and has a proxy content rights manager for when the mobile station is unable to receive secure content keys from the remote content rights manager using the air interface. In the method, content presentation units are transferred from the remote rights manager to the smart module for storage. Secure content keys are requested from the smart module for allowing presentation of content requested while the mobile station is unable to communicate with the remote rights manager. The secure content keys are transferred, based on a stored content presentation unit, from the proxy content rights manager to the security agent for allowing content presentation.

Abstract: A durable system is disclosed for controlling variable valve actuation of an engine valve corresponding to a cylinder of an automobile engine. The system is designed to have a durability that exceeds the expected life of a conventional automobile engine. The system includes first crowned cam having a first lift profile, a second crowned cam having a second lift profile, and a rocker arm assembly. The rocker assembly includes a first arm having an end connected to said engine valve, having a high impact roller following the first crowned cam operating the engine valves according to a first lift profile. The rocker arm assembly also includes a second arm having slider pads riding on the second crowned cam to operate said engine valve according to a second lift profile. The slider pads have a sliding surface covered with an impact-resistant multilayer coating with its outermost coating being a wear-resistant coating.

Abstract: Apparatus for use in the measurement of the API gravity of crude oil, comprises a conduit (1)for the oil, a thermo-couple (4) in the conduit for measuring temperature of the oil in contact therewith, a sapphire window (3) in the conduit, an infrared thermometer (5,6) for the measurement of the temperature of the oil through the window, and means (20) for comparing the measurements of temperature made by the thermometers to obtain a measure of the emissivity of the crude oil and thereby its API gravity.

Abstract: An integrated circuit includes core logic and a plurality of interface blocks disposed about a periphery of the core logic. A plurality of input or output (I/O) circuits is assigned to one of the plurality of interface blocks. The I/O circuits include external I/O circuits coupled to a device other than the integrated circuit and internal I/O circuits coupled to the integrated circuit. Each interface block includes a first plurality of I/O circuits disposed on a first side of the interface block and a second plurality of I/O circuits disposed on a second side of the interface block. Each interface block also includes interface logic for the interface block between the first plurality of I/O circuits and the second plurality of I/O circuits, and a logic hub that includes a clock distribution of minimal length that drives launch logic and capture logic to form the I/O circuits of the interface block.

Abstract: Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system configured for placement within the porous scaffold, and a seal configured to enclose a proximal opening in the porous scaffold. The device may further comprise a cell delivery device for delivering cells into the porous scaffold. The method of cell transplantation comprises a two step process. The device is incubated in the host body to form a vascularized collagen matrix around a plug positioned within the porous scaffold. The plug is then retracted from the porous scaffold, and cells are delivered into the vascularized space created within the porous scaffold.

Abstract: A micro-inverter assembly includes a housing having an opening formed in a bottom surface thereof, and a direct current (DC)-to-alternating current (AC) micro-inverter disposed within the housing at a position adjacent to the opening. The micro-inverter assembly further includes a micro-inverter DC connector electrically coupled to the DC-to-AC micro-inverter and positioned within the opening of the housing, the micro-inverter DC connector having a plurality of exposed electrical contacts.

Abstract: An alternating current (AC) harness for a photovoltaic (PV) system includes a wire assembly having a first end and a second end, the wire assembly having a plurality of lead wires, and at least one AC connection module positioned at a location along a length of the wire assembly between the first end and the second end. Further, the at least one AC connection module includes a first connection terminal electrically coupled to the plurality of lead wires of the wire assembly and constructed to electrically couple the wire assembly with an output of a first PV module of the PV system. The at least one AC connection module also includes a second connection terminal electrically coupled to the plurality of lead wires of the wire assembly and constructed to electrically couple the wire assembly with an output of a second PV module of the PV system.

Abstract: A turbine is provided and includes a rotor, which is rotatable about a centerline thereof, a sensor to measure a condition at a point of measurement interest defined on the rotor at a radial distance from the centerline, a communication system by which condition measurements are transmittable from the sensor to a non-rotating recording system and a probe holder to secure the sensor and a portion of the communication system on the rotor proximate to the point of measurement interest.