Abstract: The present invention relates to a novel process for the preparation of compounds of formula (I) wherein X, Q, R1 and R2 are as defined in the specification, the compounds being useful in the preparation of therapeutic agents. The invention further relates to novel intermediates useful in the preparation of the therapeutic agents.

Abstract: A window frame including a pair of identical frame halves that can be interconnected without fasteners. Two different connector systems are integrally formed with the frame halves, and the frame halves have two possible orientations with respect to one another—a ship orientation and an install orientation. The first connector system releasably interconnects the frame halves in either orientation. The second connector system essentially permanently interconnects the frame halves only in the install orientation—not in the ship orientation.

Abstract: The invention provides anhydrous and hydrated forms of sodium salt of N-[[4-(3,4-dichlorophenoxy)[1,4?-bipiperidin]-1?-yl]carbonyl]-4-methyl-benzenesulfonamide and crystalline forms of N-[[4-(3,4-dichlorophenoxy)[1,4?-bipiperidin]-1?-yl]carbonyl]-4-methyl-benzenesulfonamide; and such compounds are modulators of chemokine (especially CCR3) activity and are especially useful for treating asthma and/or rhinitis.

Abstract: The present invention concerns a process for preparing 4-(hydroxy)-[1,4?]bipiperidinyl-1?-carboxylic acid tert-butyl ester, comprising hydrogenating a mixture of 4-hydroxypiperidine and 1-tert-butoxycarbonyl-4-piperidone in a suitable solvent, in the presence of a suitable catalyst and at a suitable pressure.

Abstract: The invention is directed to compositions containing one or more proteases that are beneficial in the treatment of damaged tissue, wounds and inflammation. The compositions of the invention modulate the levels and activity of proteins that are present at wound and inflammation sites and promote the repair of damaged tissue.

Abstract: A method for radar protection. The method includes recording energy events and calculating differences in recorded energy events to determine pulses. The method further includes sorting intervals between pulses into histogram bins, each bin representing a range of time intervals between two pulses, each pulse indicative of a radar frequency and limiting network traffic on a frequency based on a selected bin count.

Abstract: A high efficiency electrosurgical electrode with an advanced electrically conductive tip and aspiration port, and a method of conducting an electrosurgical procedure with such electrode. The electrosurgical electrode comprises an electrically conductive tip with a central lumen or “chimney” surrounded by a plurality of protuberances. The central lumen or “chimney” is “self-cleaning” and/or “self-clearing” in that any tissue passing through the central lumen that might cause a clog is quickly denatured by the surrounding electrode and aspirated from the ablation site, so that the probe does not require special consideration by the user (for example, replacement due to total loss of suction). The plurality of protuberances have various forms and geometries that define a plurality of recesses and that, in one embodiment, are provided in a “star-shaped” or partial “star-shaped” pattern.

Abstract: A method for radar protection. The method includes recording energy events and calculating differences in recorded energy events to determine pulses. The method further includes sorting intervals between pulses into histogram bins, each bin representing a range of time intervals between two pulses, each pulse indicative of a radar frequency and limiting network traffic on a frequency based on a selected bin count.

Abstract: A composite wheel that includes a wheel having an outer surface, a plurality of exposed apertures formed in a circular pattern in a central hub region of the wheel, and a centrally-located hub aperture extending through the wheel. The composite wheel also includes a wheel cladding having a body conforming to the outer surface of the wheel, an exposed outer surface, and an inner surface facing the wheel when the wheel cladding is attached to the wheel. The wheel cladding includes at least one alignment tab extending from the inner surface and engaging the hub aperture and aligning the cladding with respect to the hub aperture, and at least one support post extending from the inner surface substantially proximate the hub aperture and structurally supporting the wheel cladding with respect to the wheel.

Abstract: A rotary abrader allowing for improved visibility during surgery and improved aspiration of waste material. This is accomplished by providing a hood or sheath formed of a clear material and is available in various shapes and sizes. Slots are provided on the cannulated tube to provide aspiration of waste material and used to attach the hood to the cannulated tube.

Abstract: This invention relates to an image processing system for capturing images from an event and for distributing images so obtained to one or more clients. The system may comprise a terminal associated with a camera and a first editing facility, wherein the terminal is configured to receive a master image file corresponding to an image of the event captured by the camera to store the master image file, to create a preview image file of a smaller file size, and to transmit the preview image file to the first editing facility, and wherein the first editing facility is configured to transmit a preview image file to a client.

Abstract: The present invention provides novel ?-O-linked glycoconjugates such as ?-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the ?-O-linked glycoconjugates.

Abstract: This invention relates to control or removal of amounts of dissolved iron that may be present in liquid process streams in the manufacture of aromatic acids. The present invention further relates to the control or removal of dissolved iron contaminants present in liquid streams during the manufacture of a crude aromatic acid. The present invention also further relates to the control or removal of dissolved iron contaminants present in liquid streams during the purification of a crude aromatic acid. The present invention also further relates to controlling of decreasing the formation of iron oxides on the surfaces of equipment used during the manufacture of crude aromatic acid and/or purification of crude aromatic acid.

Abstract: A controller equipped with a user interface having multiple-day programming capabilities, including methods of programming such devices, are disclosed. The user interface may include one or more menus or screens that can be used to program a schedule for one or more selected days during the week. An illustrative method of programming the controller may include the steps of entering a scheduling routine, selecting multiple days for schedule modification, changing the schedule parameters for one or more periods during the selected days, and then exiting the scheduling routine.

Abstract: A single-mode optical waveguide with a core, surrounded by a cladding consisting of an inner soft layer and an outer harder layer is described. The outer layer has a grating structure on its inner surface, whose spatial frequency is the same as that of the guided mode. The thickness of the inner cladding is sufficient to keep the grating outside the mode field in undeformed regions of the waveguide, so that normally no out-coupling of the light results. Connections are made by crossing two such waveguides at an angle and pressing them together. This results in deformation of the two waveguides such that the gratings are brought into proximity with the cores. Light is coupled out of one waveguide and into the other in the deformed region, resulting in a self-aligning optical connection. The out-coupled light propagates normal to the waveguide axis, so errors in the crossing angle cause little change in efficiency.

Abstract: An endoscopic rotary abrader allowing for increased burr size while maintaining the required minimum clearance between the burr and the hood. This is accomplished either by an offset configuration of non-concentric inner and outer tubes, where the inner tube is shifted laterally away from the hood, or by employing an enlarged hood.

Abstract: Devices and methods for using multiple transformers to provide a power supply to a device or system. Included are systems for using multiple transformers and multiple fuses or circuit breakers to provide a power supply. In one embodiment two transformers and two fuses or circuit breakers are used to provide a power supply. Embodiments with greater numbers of fuses and transformers are also disclosed. Also illustrated are methods and devices using thermal circuit breakers to equalize current between multiple transformer sources or to compensate for differences between multiple transformers. Also included are switched schemes for assuring proper phasing of power supply transformers.

Abstract: A conservation tillage implement having three or more rows of individual coulter wheel assemblies laterally spaced apart and removably mounted on a cultivator frame, a coulter wheel assembly in a given row being staggered with respect to the coulter wheel assemblies in a longitudinally adjacent row. The coulter wheel assemblies may be laterally adjustable and may be mounted to the cultivator frame using a mounting means that permits rotation about a vertical axis. The coulter wheel assemblies may comprise a coil spring having a horizontal spring axis to permit upward deflection in response to impact with an obstacle. Leveling attachments may optionally be mounted to the cultivator frame, along with additional field working tools. The implement is used in the management of crop residue as part of a minimum tillage strategy. The implement is particularly resistant to plugging and can be operated at high speeds without undue damage upon impact with obstacles.

Abstract: A system, apparatus, and method for preventing thermal cycling of a ballast coupled to one or more lamps. A monitor circuit is provided to monitor for activation of the ballast's thermal protection mechanism. Such monitoring may include monitoring of the ballast's thermal protection mechanism itself, or monitoring lamp current and ambient temperature in the vicinity of the ballast to determine that the ballast's thermal protection mechanism has been activated. Power to the ballast is temporarily disabled when the ballast's thermal protection mechanism has been activated, thereby preventing thermal cycling of the ballast, and consequently of the lamps, when power to the ballast has been removed.

Abstract: A wheel center cap for a vehicle wheel includes a substantially planar body portion, and a plurality of flexibly resilient fingers extending substantially orthogonal to the body portion and adapted to be received within a central aperture of a wheel. Each finger includes a pair of sidewalls and an integrally formed outer wall, wherein the outer wall includes a centrally-located portion defining a first radius of curvature, and rounded abutment portions located proximate the sidewalls and having a second radius of curvature that is less than the first radius of curvature.