Abstract: A device includes a guard member, at least one bias sensor, a display, and a measurement sensor. The guard member includes an aperture on an axis. The at least one bias sensor is coupled to the guard member. The at least one bias sensor is configured to provide a bias signal corresponding to a bias force on the guard member. The bias force is aligned parallel with the axis. The display is coupled to the at least one bias sensor and is configured to provide a visible indication of the bias force. The measurement sensor is configured to provide an output signal corresponding to a measured force proximate the aperture.

Abstract: A device includes a clamp and a sensor. The sensor can be attached to the clamp and tissue by the force exerted by the damp. The clamp includes a first jaw member having a jaw face and a second jaw member having a complementary face. The first and second jaw members are held in alignment by a joint. The joint has an elastic member configured to exert a compressive force. The joint allows movement of the jaw face relative to the complementary face in directions corresponding to pitch, roll, yaw, and heave. The compressive force is distributed over a surface of the jaw face. The sensor is coupled to the jaw face or held in place by the compressive force of the jaw face. The sensor is configured to generate a sensor signal corresponding to a physiological parameter of tissue proximate the jaw face.

Abstract: The present invention relates to chemical processes useful in the manufacture of the compound 4-(6-chloro-2,3-methylenedioxyanilino)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-tetrahydropyran-4-yloxyquinazoline (the active entity within AZD0530), to intermediates useful in the manufacture of that compound and to processes for the manufacture of those intermediates. The invention also relates to particular crystalline forms of that compound such as a difumarate salt and a trihydrate and to pharmaceutical compositions containing such crystalline forms.

Abstract: This invention provides a polyvalent vaccine comprising at least two conjugated antigens selected from a group containing glycolipid antigen, polysaccharide antigen, mucin antigen, glycosylated mucin antigen and an appropriate adjuvant. This invention also provides a multivalent vaccine comprising at least two of the following: glycosylated MUC-1-32mer, Globo H, GM2, Ley, Tn(c), sTN(c), and TF(c). This invention provides the vaccine above, wherein the adjuvant is saponin-based adjuvant. This invention provides a method for inducing immune response in a subject comprising administering an effective amount of the vaccine above to the subject. Finally, this invention provides a method for treating cancer in a subject comprising administering an appropriate amount of the vaccine above to the subject.

Abstract: A system, method, and computer program for component scattering, comprising calculating a bounding box for each of a plurality of parts; calculating a centroid corresponding to each of said bounding boxes; placing a first part having a bounding box and a centroid at said start position, and; placing said plurality of parts in a pre-determined direction from said first part; whereby in a single operation said plurality of parts are logically added to an assembly view in a pre-determined manner, and appropriate means and computer-readable instructions.

Abstract: A system, method, and computer program for radial component scattering, comprising calculating a bounding box for each of a plurality of parts; calculating a centroid corresponding to each of said bounding boxes; calculating a scatter circle for placement of said plurality of parts; calculating a number of locations to place said plurality of parts on said scatter circle; whereby said plurality of parts are added to an assembly view in a single operation such that a largest of said plurality of parts is at a start point, and appropriate means and computer-readable instructions.

Abstract: A controller equipped with a user interface having multiple-day programming capabilities, including methods of programming such devices, are disclosed. The user interface may include one or more menus or screens that can be used to program a schedule for one or more selected days during the week. An illustrative method of programming the controller may include the steps of entering a scheduling routine, selecting multiple days for schedule modification, changing the schedule parameters for one or more periods during the selected days, and then exiting the scheduling routine.

Abstract: This invention provides a catalyst and the use thereof and a process for hydrogenating carboxyaryl aldehydes with selectivity to hydroxyalkylaryl monocarboxylic acids. The catalyst comprises iridium.

Abstract: A kitchen exhaust system includes a dispenser and a receiver, with a supply spool of grease absorbent material provided in the dispenser. In a process to replace the contaminated material, portions of the web can be selectively removed from the air flow path into the receiver while drawing uncontaminated portions of the web from the dispenser to the path of air flow.

Abstract: Catalytic compositions for conversion of substituted aromatic feed materials to oxidized products comprising aromatic carboxylic acid derivatives of the substituted aromatic feed materials comprise a combination comprising a palladium component, an antimony component and/or a bismuth component, and one or more Group 4, 5, 6 or 14 metal or metalloid components. A process for oxidizing substituted aromatic feed materials comprises contacting the feed material with oxygen in the presence of such a catalytic composition in a liquid reaction mixture.

Abstract: This invention provides a polyvalent vaccine comprising at least two conjugated antigens selected from a group containing glycolipid antigen, polysaccharide antigen, mucin antigen, glycosylated mucin antigen and an appropriate adjuvant. This invention also provides a multivalent vaccine comprising at least two of the following: glycosylated MUC-1-32mer, Globo H, GM2, Ley, Tn(c), sTN(c), and TF(c). This invention provides the vaccine above, wherein the adjuvant is saponin-based adjuvant. This invention provides a method for inducing immune response in a subject comprising administering an effective amount of the vaccine above to the subject. Finally, this invention provides a method for treating cancer in a subject comprising administering an appropriate amount of the vaccine above to the subject.

Abstract: Methods of securing a support beam to a structure such as a cargo roller tray or a passenger cabin is achieved using a shear fitting. The shear fitting has a back plate which fastens to the support beam. The shear fitting additionally has parallel lugs which extend from the back plate and fasten to the structure. Web extenders which extend from the shear fitting perpendicular to the lugs may additionally be used to further fasten the support beam to the structure.

Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.

Abstract: A controller equipped with a user interface having multiple-day programming capabilities, including methods of programming such devices, are disclosed. The user interface may include one or more menus or screens that can be used to program a schedule for one or more selected days during the week. An illustrative method of programming the controller may include the steps of entering a scheduling routine, selecting multiple days for schedule modification, changing the schedule parameters for one or more periods during the selected days, and then exiting the scheduling routine.

Abstract: An animal feeder which is adapted to simultaneously dispense feed and liquid onto a feed material receiving member.

Abstract: Systems and methods provide for more efficient cleaning and sterilizing of surgical handpieces by using a removable valve assembly. The valve assembly is removable to provide access to a first suction passageway and a second suction passageway for cleaning purposes. The first suction passageway may also be removable.

Abstract: A controller equipped with a user interface having multiple-day programming capabilities, including methods of programming such devices, are disclosed. The user interface may include one or more menus or screens that can be used to program a schedule for one or more selected days during the week. An illustrative method of programming the controller may include the steps of entering a scheduling routine, selecting multiple days for schedule modification, changing the schedule parameters for one or more periods during the selected days, and then exiting the scheduling routine.

Abstract: An apparatus and methods for forming a composite part are provided. A method for forming a composite part may include placing initial composite material on a base tool, placing a tooling mandrel on the composite material, placing additional composite material over the tooling mandrel, covering at least a portion of the composite material that overlays the tooling mandrel with a composite forming tool, heating the composite material to at least partially cure the composite material, and permitting a first portion of the composite forming tool to change size during the heating of the composite material to a greater degree than a second portion of the composite forming tool. In this regard, the second portion of the composite forming tool is closer to the base tool than the first portion of the composite forming tool. A composite forming tool is provided that permits differential expansion of different portions of the tool.

Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.

Abstract: A kitchen exhaust system includes a dispenser and a receiver, with a supply spool of grease absorbent material provided in the dispenser. In a process to replace the contaminated material, portions of the web can be selectively removed from the air flow path into the receiver while drawing uncontaminated portions of the web from the dispenser to the path of air flow.