Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.

Abstract: A method is provided of identifying a handover target femtocell base station from among multiple femtocell base stations.

Abstract: A device includes a sensor for measuring a parameter for tissue. The sensor includes a plurality of optical elements including a plurality of detectors and at least one emitter. Separation distances between the various optical elements are selected based on a depth corresponding to a region of interest in the tissue and based on a depth corresponding to an exclusion region in the tissue.

Abstract: A method of producing a flavoured tobacco smoke filter or filter element comprising a self sustaining longitudinally extending cylindrical core comprising fibres or filaments of tobacco smoke filtering material which are bonded at their points of contact; the method comprising a step of applying a flavouring agent to a longitudinally advancing flow of filters and/or filter elements and/or multiple filter rods. Filters and filter elements are also provided.

Abstract: A remote pulse TDR liquid level measurement system and method may include inserting a probe into a body of water. The probe has a probe/air interface, and the body of water includes an air/water interface. A narrow pulse is remotely transmitted to the probe via a coaxial cable. A first impedance mismatch is received from the probe/air interface in a form of a positive reflected pulse, and a second impedance mismatch is received from the air/water interface in a form of a negative reflected pulse. A time between the positive reflected pulse and the negative reflected pulse is calculated, and the time is converted to a distance, the distance being indicative of the water level.

Abstract: A device includes a sensor for measuring a parameter for tissue. The sensor includes a plurality of optical elements including a plurality of detectors and at least one emitter. Separation distances between the various optical elements are selected based on a depth corresponding to a region of interest in the tissue and based on a depth corresponding to an exclusion region in the tissue.

Abstract: A device includes a clamp and a sensor. The sensor can be attached to the clamp and tissue by the force exerted by the clamp. The clamp includes a first jaw member having a jaw face and a second jaw member having a complementary face. The first and second jaw members are held in alignment by a joint. The joint has an elastic member configured to exert a compressive force. The joint allows movement of the jaw face relative to the complementary face in directions corresponding to pitch, roll, yaw, and heave. The compressive force is distributed over a surface of the jaw face. The sensor is coupled to the jaw face or held in place by the compressive force of the jaw face. The sensor is configured to generate a sensor signal corresponding to a physiological parameter of tissue proximate the jaw face.

Abstract: An apparatus includes a first amplifier having a first input coupled to a first optical detector. The first amplifier includes a first output corresponding to a logarithm of the first input. The apparatus includes a second amplifier having a second input coupled to a second optical detector and having a second output corresponding to a logarithm of the second input. The apparatus includes a differential amplifier configured to amplify a difference between the first output and the second output.

Abstract: A computerized system and method for communicating about digital content. In one embodiment, the system allows users to view and post video comments about source digital content. Typically, the source digital content and associated videos comments are assigned unique identifications so the relationships among videos can be stored in a central database. This means that video comments about source digital content can be decentralized since the source digital content has unique identifiers throughout websites and the relationship with any associated videos can be determined based on relationships stored in the database.

Abstract: This invention provides a polyvalent vaccine comprising at least two conjugated antigens selected from a group containing glycolipid antigen, polysaccharide antigen, mucin antigen, glycosylated mucin antigen and an appropriate adjuvant. This invention also provides a multivalent vaccine comprising at least two of the following: glycosylated MUC-1-32mer, Globo H, GM2, Ley, Tn(c), sTN(c), and TF(c). This invention provides the vaccine above, wherein the adjuvant is saponin-based adjuvant. This invention provides a method for inducing immune response in a subject comprising administering an effective amount of the vaccine above to the subject. Finally, this invention provides a method for treating cancer in a subject comprising administering an appropriate amount of the vaccine above to the subject.

Abstract: Disclosed are 6-(morpholinoalkyl)-substituted pyridines, and pharmaceutically acceptable salts and prodrugs thereof, that are active against a range of mammalian therapeutic indications.

Abstract: The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive glycoconjugates as disclosed herein.

Abstract: Catalytic compositions for conversion of substituted aromatic feed materials to oxidized products comprising aromatic carboxylic acid derivatives of the substituted aromatic feed materials comprise solid particles comprising palladium in combination with at least one of antimony, bismuth and gold, and optionally, an additional metal or metalloid component effective to promote activity or selectivity of the palladium and antimony, bismuth or gold for oxidation to aromatic carboxylic acids. A process for oxidizing substituted aromatic feed materials comprises contacting the feed material with oxygen in the presence of such catalytic compositions in a liquid reaction mixture.

Abstract: A controller equipped with a user interface having multiple-day programming capabilities, including methods of programming such devices, are disclosed. The user interface may include one or more menus or screens that can be used to program a schedule for one or more selected days during the week. An illustrative method of programming the controller may include the steps of entering a scheduling routine, selecting multiple days for schedule modification, changing the schedule parameters for one or more periods during the selected days, and then exiting the scheduling routine.

Abstract: A non stick, heat resistant and washable door liner shield (2) may include a handle (4) or flap which is attached to the top of the door shield. The handle or flap (6) may include a picture of a pan or casserole dish with text. The handle may also include a magnet (5) or sucker to allow the fixing of the oven door shield to the oven door.

Abstract: This invention provides a polyvalent vaccine comprising at least two conjugated antigens selected from a group containing glycolipid antigen, polysaccharide antigen, mucin antigen, glycosylated mucin antigen and an appropriate adjuvant. This invention also provides a multivalent vaccine comprising at least two of the following: glycosylated MUC-1-32mer, Globo H, GM2, Ley, Tn(c), sTN(c), and TF(c). This invention provides the vaccine above, wherein the adjuvant is saponin-based adjuvant. This invention provides a method for inducing immune response in a subject comprising administering an effective amount of the vaccine above to the subject. Finally, this invention provides a method for treating cancer in a subject comprising administering an appropriate amount of the vaccine above to the subject.

Abstract: An apparatus and methods for forming a composite part are provided. A method for forming a composite part may include placing initial composite material on a base tool, placing a tooling mandrel on the composite material, placing additional composite material over the tooling mandrel, covering at least a portion of the composite material that overlays the tooling mandrel with a composite forming tool, heating the composite material to at least partially cure the composite material, and permitting a first portion of the composite forming tool to change size during the heating of the composite material to a greater degree than a second portion of the composite forming tool. In this regard, the second portion of the composite forming tool is closer to the base tool than the first portion of the composite forming tool. A composite forming tool is provided that permits differential expansion of different portions of the tool.

Abstract: Impure aromatic carboxylic acids such as are obtained by liquid phase oxidation of feed materials comprising aromatic compounds with substituent groups oxidizable to carboxylic acid groups, or comprising aromatic carboxylic acid and one or more aromatic carbonyl impurities that form hydrogenated species more soluble in aqueous solvents or with less color or color-forming tendencies than the aromatic carbonyl impurity, are purified to an aromatic carboxylic acid product with lower levels of impurities by a process comprising contacting an aqueous solution comprising the impure aromatic carboxylic acid with hydrogen at elevated temperature and pressure with an attrition-resistance, acid stable catalyst composition comprising at least one hydrogenation catalyst metal and a support comprising relatively high surface area silicon carbide.

Abstract: Disclosed are 6-(morpholinoalkyl)-substituted pyridines, and pharmaceutically acceptable salts and prodrugs thereof, that are active against a range of mammalian therapeutic indications.

Abstract: Glycopeptide conjugates comprising GM2 and/or Gb5 carbohydrate determinants, and methods of making and using such conjugates are disclosed. The immunogenicity of select glycopeptide conjugates is demonstrated.