Abstract: The invention relates to a method for the operational analysis of an engine and/or for calibrating a controller of the engine, in particular an internal combustion engine, wherein run-up occurs of test points defined by values of a plurality of predetermined operating parameters and selected from a multidimensional test space using a statistical experiment design, whereby at least one operating parameter is in each case changed from one test point to the next test point in a plurality of steps in the run-up of the test points, wherein operational measurements are performed at measurement points resulting from a respective increment and at the actual test points, whereby measurement data from the operational measurements for the analysis and calibration of the controller are output and continuously stored, as well as a corresponding system.

Abstract: Data is received that specifies a bound for an adversarial posterior belief ?c that corresponds to a likelihood to re-identify data points from the dataset based on a differentially private function output. Privacy parameters ?, ? are then calculated based on the received data that govern a differential privacy (DP) algorithm to be applied to a function to be evaluated over a dataset. The calculating is based on a ratio of probabilities distributions of different observations, which are bound by the posterior belief ?c as applied to a dataset. The calculated privacy parameters are then used to apply the DP algorithm to the function over the dataset. Related apparatus, systems, techniques and articles are also described.

Abstract: The present invention relates to T cell receptors (TCRs) that bind the HLA-A*02 restricted peptide SLLQHLIGL (SEQ ID NO: 1) derived from the germline cancer antigen PRAME. Said TCRs may comprise non-natural mutations within the alpha and/or beta variable domains relative to a native PRAME TCR. The TCRs of the invention are particularly suitable for use as novel immunotherapeutic reagents for the treatment of malignant disease.

Abstract: A method includes determining a cluster reliability of a computing cluster including a maximum computing capacity and representative of a reliability of the computing cluster when utilizing an entirety of the maximum computing capacity. The operations include receiving a provisioning request of the computing cluster including a threshold reliability of the computing cluster. In response to the provisioning request, determining, using the cluster reliability, a reserved computing capacity of the computing cluster based on the threshold reliability. The reserved computing capacity is less than the maximum computing capacity. Based on the reserved computing capacity and the maximum computing capacity, the operations include determining an unreserved computing capacity of the computing cluster. The operations include provisioning the computing cluster for execution of a user workload. The user workload executes on the unreserved computing capacity.

Abstract: A vehicle includes first and second drive units, such as drive units that each include an electric motor and a gear train coupling the electric motor to one or more wheels. A first drive unit may be idled while the second drive unit continues to induce movement of the vehicle. Losses within the first drive unit while idled may be reduced by heating the first drive unit, such as with heat generated by the second drive unit. A cooling system is present and may be used to heat the first drive unit by directing fluid exiting the second drive unit into the first drive unit before entering the cooling system or bypassing the cooling system entirely. Oil circulation within the first drive unit may facilitate heating of the gear train by bypassing a heat exchanger receiving the oil and the fluid.

Abstract: Data is received that specifies a bound for an adversarial posterior belief ?c that corresponds to a likelihood to re-identify data points from the dataset based on a differentially private function output. Privacy parameters ?, ? are then calculated based on the received data that govern a differential privacy (DP) algorithm to be applied to a function to be evaluated over a dataset. The calculating is based on a ratio of probabilities distributions of different observations, which are bound by the posterior belief ?c as applied to a dataset. The calculated privacy parameters are then used to apply the DP algorithm to the function over the dataset. Related apparatus, systems, techniques and articles are also described.

Abstract: The present invention relates to T cell receptors (TCRs) that bind the HLA-A*02 restricted peptide SLLQHLIGL (SEQ ID NO: 1) derived from the germline cancer antigen PRAME. Said TCRs may comprise non-natural mutations within the alpha and/or beta variable domains relative to a native PRAME TCR. The TCRs of the invention are particularly suitable for use as novel immunotherapeutic reagents for the treatment of malignant disease.

Abstract: Data is received that specifies a bound for an adversarial posterior belief ?c that corresponds to a likelihood to re-identify data points from the dataset based on a differentially private function output. Privacy parameters ?, ? are then calculated based on the received data that govern a differential privacy (DP) algorithm to be applied to a function to be evaluated over a dataset. The calculating is based on a ratio of probabilities distributions of different observations, which are bound by the posterior belief ?c as applied to a dataset. The calculated privacy parameters are then used to apply the DP algorithm to the function over the dataset. Related apparatus, systems, techniques and articles are also described.

Abstract: An apparatus for manufacturing a composite article from a composite material. The apparatus comprising: a pulsed broadband radiation source comprising a flashlamp and a light guide adapted to guide light emitted by the pulsed broadband radiation source to a target area. The light guide comprises at least a portion ahead of the pulsed broadband radiation source, relative to the target area, comprising a light transmitting material.

Abstract: A method for removing a guided wave noise in a time-domain may include recording one or more acoustic signals with one or more receivers at a first location, wherein the one or more acoustic signals are raw data. The method may further include determining a slowness range, estimating a downward guided wave noise by stacking the one or more acoustic signals based at least in part on a positive slowness, estimating an upward guided wave noise by stacking the one or more acoustic signals based at least in part on a negative slowness, and identifying a dominant direction of propagation. The method may further include identifying a slowness from a highest stacked amplitude for the dominant direction of propagation, estimating a downward guided wave noise with the slowness, estimating an upward guided wave noise with the slowness, and subtracting the downward guided wave noise and the upward guided wave noise.

Abstract: The present invention relates to T cell receptors (TCRs) that bind the HLA-A*02 restricted peptide SLLQHLIGL (SEQ ID NO: 1) derived from the germline cancer antigen PRAME. Said TCRs may comprise non-natural mutations within the alpha and/or beta variable domains relative to a native PRAME TCR. The TCRs of the invention are particularly suitable for use as novel immunotherapeutic reagents for the treatment of malignant disease.

Abstract: A method includes determining a cluster reliability of a computing cluster including a maximum computing capacity and representative of a reliability of the computing cluster when utilizing an entirety of the maximum computing capacity. The operations include receiving a provisioning request of the computing cluster including a threshold reliability of the computing cluster. In response to the provisioning request, determining, using the cluster reliability, a reserved computing capacity of the computing cluster based on the threshold reliability. The reserved computing capacity is less than the maximum computing capacity. Based on the reserved computing capacity and the maximum computing capacity, the operations include determining an unreserved computing capacity of the computing cluster. The operations include provisioning the computing cluster for execution of a user workload. The user workload executes on the unreserved computing capacity.

Abstract: The technology described herein helps a student learn how to read by determining a present reading level for the student and dynamically providing feedback that accurately identifies the specific oral reading errors made. The failure to identify oral reading mistakes, such as hesitations (‘uh-uh . . . pony’), word omissions, word or syllable insertions and other errors, results in inaccurate student assessment and proficiency scoring, as well as suboptimal learning feedback being provided back to the student. Allowing a student to understand the type of errors made helps the student avoid the same errors in subsequent efforts and helps the student understand what correct reading is. The system receives an oral reading attempt, identifies errors, classifies, the errors, and provides a proficiency score for the oral reading attempt. A report detailing the errors may also be generated.

Abstract: A drivetrain system includes a first drive gear driven by a first motor and a second drive gear driven by a second motor. The first drive gear and the second drive gear are arranged along the axis. The first drive gear includes a first extension and the second drive gear includes a second extension arranged radially within and axially overlapping the first extension. The drivetrain system includes a system of bearings arranged between the first drive gear and the second drive gear, either drive gear and a stationary component, or a combination thereof. In some embodiments, the drivetrain system includes a clutch assembly arranged between the first drive gear and the second drive gear that interfaces to the first drive gear and to the second drive gear. The clutch assembly allows the drive gears to be locked or otherwise engaged to improve torque transfer.

Abstract: The present invention relates to T cell receptors (TCRs) that bind the HLA-A*02 restricted peptide SLLQHLIGL (SEQ ID NO: 1) derived from the germline cancer antigen PRAME. Said TCRs may comprise non-natural mutations within the alpha and/or beta variable domains relative to a native PRAME TCR. The TCRs of the invention are particularly suitable for use as novel immunotherapeutic reagents for the treatment of malignant disease.

Abstract: The technology described herein helps a student learn how to read by providing text at a reading level suitable for learning. The technology described herein can take an input text and adjust the reading level to match the target reading level. The text can be adjusted through word substitution. Prior to outputting the complexified text, a grammar check can determine that the substitution did not generate a grammatically incorrect complexified text.

Abstract: A first signal is ready from a first machine-readable object, which may be part of a peg stored in a surgical asset tray. A first part number of a first surgical asset is identified based on the first signal. A label is printed to include a first machine-readable visual indicia representing the first part number. A second signal is optically read from the first machine-readable visual indicia. The first part number of the first surgical asset is identified based on the second signal. The first part number of the first surgical asset is stored in a non-transitory computer-readable medium. This method enables information about surgical assets used in the field to be transferred from machine-readable objects into electronic data stores efficiently, effectively, and semi-automatically.

Abstract: A drivetrain system includes a first drive gear driven by a first motor and a second drive gear driven by a second motor. The first drive gear and the second drive gear are arranged along the axis. The first drive gear includes a first extension and the second drive gear includes a second extension arranged radially within and axially overlapping the first extension. The drivetrain system includes a system of bearings arranged between the first drive gear and the second drive gear, either drive gear and a stationary component, or a combination thereof. In some embodiments, the drivetrain system includes a clutch assembly arranged between the first drive gear and the second drive gear that interfaces to the first drive gear and to the second drive gear. The clutch assembly allows the drive gears to be locked or otherwise engaged to improve torque transfer.

Abstract: A drivetrain system includes a first drive gear driven by a first motor and a second drive gear driven by a second motor. The first drive gear and the second drive gear are arranged along the axis. The first drive gear includes a first extension and the second drive gear includes a second extension arranged radially within and axially overlapping the first extension. The drivetrain system includes a system of bearings arranged between the first drive gear and the second drive gear, either drive gear and a stationary component, or a combination thereof. In some embodiments, the drivetrain system includes a clutch assembly arranged between the first drive gear and the second drive gear that interfaces to the first drive gear and to the second drive gear. The clutch assembly allows the drive gears to be locked or otherwise engaged to improve torque transfer.