Patents by Inventor Philip Wilson

Philip Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7265105
    Abstract: A compound of the formula II: wherein: R?2 is CHR?2, where R?2 is H. R6 and R9 are H and R7 is OMe and the compound is a dimer with each monomer being the same and being of formula II, where the R8 groups of the monomers form together a bridge having the formula —O—(CH2)p—O—, where p is 5, linking the monomers.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: September 4, 2007
    Assignee: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Patent number: 7067511
    Abstract: Compounds of the formulae Ia and Ib: wherein: A is CH2, or a single bond; R2 is selected from: R, OH, OR, CO2H, CO2R, COH, COR, SO2R, CN; R6, R7 and R9 are independently selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn; and R8 is selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn, where R is as defined above, or the compound is a dimer with each monomer being the same or different and being of formula Ia or Ib, where the R8 groups of the monomers form together a bridge having the formula —X—R?—X— linking the monomers, where R? is an alkylene chain containing from 3 to 12 carbon atoms, which chain may be interrupted by one or more hetero-atoms and/or aromatic rings and may contain one or more carbon-carbon double or triple bonds, and each X is independently selected from O, S, or N; except that in a compound of formula Ia when A is a single bond, then R2 is not CH?CH(CONH2) or CH?CH(CONMe2). Other related compounds are also disclosed.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: June 27, 2006
    Assignee: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Patent number: 7049311
    Abstract: Compounds of formula (Ia) and (Ib) wherein A is CH2, or a single bond; R2 is selected from: R, OH, OR, CO2H, CO2R, COH, COR, SO2R, CN; R6, R7 and R9 are independently selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn; and R8 is selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn, where R is as defined above, or the compound is a dimer with each monomer being the same or different and being of formula (Ia) or (Ib), where the R8 groups of the monomers form together a bridge having the formula —X—R?—X— linking the monomers, where R? is an alkylene chain containing from 3 to 12 carbon atoms, which chain may be interrupted by one or more hetero-atoms and/or aromatic rings and may contain one or more carbon—carbon double or triple bonds, and each X is independently selected from O, S, or N; except that in a compound of formula (Ia) when A is a single bond, then R2 is not CH?CH(CONH2) or CH?CH(CONMe2).
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: May 23, 2006
    Assignee: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Patent number: 6909006
    Abstract: Compounds of formula (III) or (V), wherein is a solid support; L is a linking group or a single bond; T is a combinatorial unit; n is a positive integer, where if n is greater than 1, each T may be different: X is an electrophilic leaving group; Y is selected from NH-Prot, O-Prot, S-Prot, NO2, —NHOH. N3, NHR, NRR, N?NR, N(O)RR, NHSO2R, N?N?PhR, SR or SSR, where Prot represents a protecting group; A and B collectively represent a fused benzene or pyrrole ring (in either orientation), which is optionally substituted by up to respectively 4 or 2 groups independently selected from R, OH, OR, halo, nitro, amino, Me3Sn, CO2H, CO2R, R1 is a nitrogen protecting group, where if Y includes a protecting group, these protecting groups are orthogonal and R2 and R7 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn, and other related compounds and collections of compounds.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: June 21, 2005
    Assignee: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Patent number: 6849716
    Abstract: The invention relates to methods for designing inhibitors of serine/threonine kinases and tyrosine kinases, particularly MAP kinases, through the use of ATP-binding site mutants of those kinases. The methods of this invention take advantage of the fact that the mutant kinases are capable of binding inhibitory compounds of other kinases with greater affinity than the corresponding wild-type kinase. The invention further relates to the mutant kinases themselves and crystallizable co-complexes of the mutant kinase and the inhibitory compound.
    Type: Grant
    Filed: August 18, 2000
    Date of Patent: February 1, 2005
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Michael Shin-San Su, Ted Fox, Keith Philip Wilson, Ursula A. Germann
  • Publication number: 20040259166
    Abstract: The invention relates to methods for designing inhibitors of serine/threonine kinases and tyrosine kinases, particularly MAP kinases, through the use of ATP-binding site mutants of those kinases. The methods of this invention take advantage of the fact that the mutant kinases are capable of binding inhibitory compounds of other kinases with greater affinity than the corresponding wild-type kinase. The invention further relates to the mutant kinases themselves and crystallizable co-complexes of the mutant kinase and the inhibitory compound.
    Type: Application
    Filed: July 15, 2004
    Publication date: December 23, 2004
    Inventors: Michael Shin-San Su, Ted Fox, Keith Philip Wilson, Ursula A. Germann
  • Publication number: 20040243351
    Abstract: A vehicle noise, vibration and harshness analysis tool according to the present invention comprises at least one sensor, each sensing a vibration or noise and generating a signal at a frequency related to the vibration or noise. A communication link with a vehicle is included to transmit data regarding the vehicle. A microprocessor system receives the signals generated by said at least one sensor and receives the vehicle data over said communication link. The microprocessor system conducts an analysis of the received sensor signals and vehicle data and identifies a vehicle component that is likely causing a vibration or noise. The microprocessor system also identifies the possible problems with the identified vehicle component. A user interface is also included with a display. The microprocessor system causes the display to list the likely vehicle components causing the vibration or noise and the possible problems with the components.
    Type: Application
    Filed: June 30, 2004
    Publication date: December 2, 2004
    Applicant: VETRONIX CORPORATION
    Inventors: Thomas R. Calkins, Philip Wilson
  • Publication number: 20040198722
    Abstract: A compound of formula (I), wherein: R2 and R3 are independently selected from H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R, CH2—CO2H, CH2—SO2R, O—SO2R, CO2R, COR and CN, and there is optionally a double bond between C1 and C2 or C2 and C3; R6, R7, R8 and R9 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn; R11 is either H or R; Q is S, O or NH; L is a linking group, or a single bond; O is a solid support; or where one or more of R2, R3, R6, R7 and R8 are independently: H—(T)n—X—Y—A— where: X is CO, NH, S or O; T is a combinatorial unit; Y is a divalent group such that HY═R; A is O, S, NH, or a single bond and n is a positive integer.
    Type: Application
    Filed: April 15, 2004
    Publication date: October 7, 2004
    Applicant: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Patent number: 6747144
    Abstract: A compound of formula (I), wherein: R2 and R3 are independently selected from H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R, CH2—CO2H, CH2—SO2R, O—SO2R, CO2R, COR and CN, and there is optionally a double bond between C1 and C2 or C2 and C3; R6, R7, R8 and R9 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn; R11 is either H or R; Q is S, O or NH; L is a linking group, or a single bond; O is a solid support; or where one or more of R2, R3, R6, R7 and R8 are independently: H—(T)n—X—Y—A— where: X is CO, NH, S or O; T is a combinatorial unit; Y is a divalent group such that HY=R; A is O, S, NH, or a single bond and n is a positive integer
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: June 8, 2004
    Assignee: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Publication number: 20040092736
    Abstract: A compound of formula (IV): O is a solid support; L is a linking group or a single bond; X′ is selected from CO, NH, S, or O; A is O, S, NH, or a single bond; R2 and R3 are independently selected from: H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R, CH2—CO2H, CH2—SO2R, O—SO2R, CO2R, COR, CN and there is optionally a double bond between C1 and C2 or C2 and C3; R6, R7, and R9 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn; R11 is either H or R; Q is S, O or NH; R10 is a nitrogen protecting group; and Y is a divalent group such that HY═R, and other related compounds and collections of compounds.
    Type: Application
    Filed: June 24, 2003
    Publication date: May 13, 2004
    Applicant: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Publication number: 20030195196
    Abstract: A compound with formula (I) 1
    Type: Application
    Filed: March 4, 2003
    Publication date: October 16, 2003
    Applicant: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Publication number: 20030165899
    Abstract: The invention relates to methods for designing inhibitors of serine/threonine kinases and tyrosine kinases, particularly MAP kinases, through the use of ATP-binding site mutants of those kinases. The methods of this invention take advantage of the fact that the mutant kinases are capable of binding inhibitory compounds of other kinases with greater affinity than the corresponding wild-type kinase. The invention further relates to the mutant kinases themselves and crystallizable co-complexes of the mutant kinase and the inhibitory compound.
    Type: Application
    Filed: June 12, 2002
    Publication date: September 4, 2003
    Applicant: Vertex Pharmaceuticals, Inc.
    Inventors: Michael Shin-San Su, Ted Fox, Keith Philip Wilson, Ursula A. Germann
  • Patent number: 6608192
    Abstract: A compound of formula (IV): O is a solid support; L is a linking group or a single bond; X′ is selected from CO, NH, S, or O; A is O, S, NH, or a single bond; R2 and R3 are independently selected from: H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R′, CH2—CO2H, CH2—SO2R, O—SO2R, CO2R, COR, CN and there is optionally a double bond between C1 and C2 or C2 and C3; R6, R7, and R9 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn; R11 is either H or R; Q is S, O or NH; R10 is a nitrogen protecting group; and Y is a divalent group such that HY=R, and other related compounds and collections of compounds.
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: August 19, 2003
    Assignee: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Publication number: 20030120069
    Abstract: Compounds of the formulae Ia and Ib: 1
    Type: Application
    Filed: December 12, 2001
    Publication date: June 26, 2003
    Applicant: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Patent number: 6574377
    Abstract: A method and apparatus for storing and retrieving images of documents, e.g. checks.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: June 3, 2003
    Assignee: The Chase Manhattan Bank
    Inventors: Thomas Cahill, Louise A. McNulty, John J. McMonagle, Richard H. Sferra, Glenn Levine, Saul Goldfisher, Philip Wilson, Vladimir Koroteyev
  • Patent number: 6562806
    Abstract: A compound with formula (I) where R10 is a therapeutically removable nitrogen protecting group; R2 and R3 are independently selected from: H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R, CH2—CO2H, CH2—SO2R, O—SO2—R, CO2R, COR and CN; R6, R7 and R9 are independently selected from H, R, OH, OR, halo, amino, nitro, Me3Sn; X is S, O or NH; R11 is either H or R; and where there is optionally a double bond between C1 and C2 or C2 and C3; and R8 is selected from H, R, OH, OR, halo, amino, nitro, Me3Sn, or R7 and R8 together form a group —O—(CH2)p—O—, where p is 1 or 2. Such compounds may be used in methods of ADEPT, GDEPT, NPEPT or PDT.
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: May 13, 2003
    Assignee: Spirogen Limited
    Inventors: David Edwin Thurston, Philip Wilson Howard
  • Publication number: 20030088346
    Abstract: A vehicle noise, vibration and harshness analysis tool according to the present invention comprises at least one sensor, each sensing a vibration or noise and generating a signal at a frequency related to the vibration or noise. A communication link with a vehicle is included to transmit data regarding the vehicle. A microprocessor system receives the signals generated by said at least one sensor and receives the vehicle data over said communication link. The microprocessor system conducts an analysis of the received sensor signals and vehicle data and identifies a vehicle component that is likely causing a vibration or noise. The microprocessor system also identifies the possible problems with the identified vehicle component. A user interface is also included with a display. The microprocessor system causes the display to list the likely vehicle components causing the vibration or noise and the possible problems with the components.
    Type: Application
    Filed: October 25, 2002
    Publication date: May 8, 2003
    Applicant: VETRONIX CORPORATION
    Inventors: Thomas R. Calkins, Philip Wilson
  • Patent number: 6320287
    Abstract: A combination of a rotor and a stator assembly, the stator assembly having a first part and a second part, the first and second parts being generally concentric, the rotor being rotatably mounted in the stator assembly, the combination further including a plurality of elongate resilient damping elements which extend generally in an axial direction, and being located between and spacing apart the first part and the second part of the stator assembly.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: November 20, 2001
    Assignee: Normalair-Garret (Holdings) Limited
    Inventors: Stephen Richard Watson, Malcolm Philip Wilson
  • Patent number: D452910
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: January 8, 2002
    Assignee: Innovata Biomend Limited
    Inventors: Philip Wilson Braithwaite, Steven Graham Williams
  • Patent number: D563788
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: March 11, 2008
    Assignee: JohnsonDiversey, Inc.
    Inventors: Kirk M. Reimann, Daniel Newman, Philip Wilson, Rajnikant Desai, Darold Faurot, Eric Weldzius