Patents by Inventor Philip Wilson
Philip Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 7265105Abstract: A compound of the formula II: wherein: R?2 is CHR?2, where R?2 is H. R6 and R9 are H and R7 is OMe and the compound is a dimer with each monomer being the same and being of formula II, where the R8 groups of the monomers form together a bridge having the formula —O—(CH2)p—O—, where p is 5, linking the monomers.Type: GrantFiled: March 2, 2006Date of Patent: September 4, 2007Assignee: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Patent number: 7067511Abstract: Compounds of the formulae Ia and Ib: wherein: A is CH2, or a single bond; R2 is selected from: R, OH, OR, CO2H, CO2R, COH, COR, SO2R, CN; R6, R7 and R9 are independently selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn; and R8 is selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn, where R is as defined above, or the compound is a dimer with each monomer being the same or different and being of formula Ia or Ib, where the R8 groups of the monomers form together a bridge having the formula —X—R?—X— linking the monomers, where R? is an alkylene chain containing from 3 to 12 carbon atoms, which chain may be interrupted by one or more hetero-atoms and/or aromatic rings and may contain one or more carbon-carbon double or triple bonds, and each X is independently selected from O, S, or N; except that in a compound of formula Ia when A is a single bond, then R2 is not CH?CH(CONH2) or CH?CH(CONMe2). Other related compounds are also disclosed.Type: GrantFiled: December 12, 2001Date of Patent: June 27, 2006Assignee: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Patent number: 7049311Abstract: Compounds of formula (Ia) and (Ib) wherein A is CH2, or a single bond; R2 is selected from: R, OH, OR, CO2H, CO2R, COH, COR, SO2R, CN; R6, R7 and R9 are independently selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn; and R8 is selected from H, R, OH, OR, halo, amino, NHR, nitro, Me3Sn, where R is as defined above, or the compound is a dimer with each monomer being the same or different and being of formula (Ia) or (Ib), where the R8 groups of the monomers form together a bridge having the formula —X—R?—X— linking the monomers, where R? is an alkylene chain containing from 3 to 12 carbon atoms, which chain may be interrupted by one or more hetero-atoms and/or aromatic rings and may contain one or more carbon—carbon double or triple bonds, and each X is independently selected from O, S, or N; except that in a compound of formula (Ia) when A is a single bond, then R2 is not CH?CH(CONH2) or CH?CH(CONMe2).Type: GrantFiled: August 27, 1999Date of Patent: May 23, 2006Assignee: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Patent number: 6909006Abstract: Compounds of formula (III) or (V), wherein is a solid support; L is a linking group or a single bond; T is a combinatorial unit; n is a positive integer, where if n is greater than 1, each T may be different: X is an electrophilic leaving group; Y is selected from NH-Prot, O-Prot, S-Prot, NO2, —NHOH. N3, NHR, NRR, N?NR, N(O)RR, NHSO2R, N?N?PhR, SR or SSR, where Prot represents a protecting group; A and B collectively represent a fused benzene or pyrrole ring (in either orientation), which is optionally substituted by up to respectively 4 or 2 groups independently selected from R, OH, OR, halo, nitro, amino, Me3Sn, CO2H, CO2R, R1 is a nitrogen protecting group, where if Y includes a protecting group, these protecting groups are orthogonal and R2 and R7 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn, and other related compounds and collections of compounds.Type: GrantFiled: February 22, 2000Date of Patent: June 21, 2005Assignee: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Patent number: 6849716Abstract: The invention relates to methods for designing inhibitors of serine/threonine kinases and tyrosine kinases, particularly MAP kinases, through the use of ATP-binding site mutants of those kinases. The methods of this invention take advantage of the fact that the mutant kinases are capable of binding inhibitory compounds of other kinases with greater affinity than the corresponding wild-type kinase. The invention further relates to the mutant kinases themselves and crystallizable co-complexes of the mutant kinase and the inhibitory compound.Type: GrantFiled: August 18, 2000Date of Patent: February 1, 2005Assignee: Vertex Pharmaceuticals IncorporatedInventors: Michael Shin-San Su, Ted Fox, Keith Philip Wilson, Ursula A. Germann
-
Publication number: 20040259166Abstract: The invention relates to methods for designing inhibitors of serine/threonine kinases and tyrosine kinases, particularly MAP kinases, through the use of ATP-binding site mutants of those kinases. The methods of this invention take advantage of the fact that the mutant kinases are capable of binding inhibitory compounds of other kinases with greater affinity than the corresponding wild-type kinase. The invention further relates to the mutant kinases themselves and crystallizable co-complexes of the mutant kinase and the inhibitory compound.Type: ApplicationFiled: July 15, 2004Publication date: December 23, 2004Inventors: Michael Shin-San Su, Ted Fox, Keith Philip Wilson, Ursula A. Germann
-
Publication number: 20040243351Abstract: A vehicle noise, vibration and harshness analysis tool according to the present invention comprises at least one sensor, each sensing a vibration or noise and generating a signal at a frequency related to the vibration or noise. A communication link with a vehicle is included to transmit data regarding the vehicle. A microprocessor system receives the signals generated by said at least one sensor and receives the vehicle data over said communication link. The microprocessor system conducts an analysis of the received sensor signals and vehicle data and identifies a vehicle component that is likely causing a vibration or noise. The microprocessor system also identifies the possible problems with the identified vehicle component. A user interface is also included with a display. The microprocessor system causes the display to list the likely vehicle components causing the vibration or noise and the possible problems with the components.Type: ApplicationFiled: June 30, 2004Publication date: December 2, 2004Applicant: VETRONIX CORPORATIONInventors: Thomas R. Calkins, Philip Wilson
-
Publication number: 20040198722Abstract: A compound of formula (I), wherein: R2 and R3 are independently selected from H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R, CH2—CO2H, CH2—SO2R, O—SO2R, CO2R, COR and CN, and there is optionally a double bond between C1 and C2 or C2 and C3; R6, R7, R8 and R9 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn; R11 is either H or R; Q is S, O or NH; L is a linking group, or a single bond; O is a solid support; or where one or more of R2, R3, R6, R7 and R8 are independently: H—(T)n—X—Y—A— where: X is CO, NH, S or O; T is a combinatorial unit; Y is a divalent group such that HY═R; A is O, S, NH, or a single bond and n is a positive integer.Type: ApplicationFiled: April 15, 2004Publication date: October 7, 2004Applicant: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Patent number: 6747144Abstract: A compound of formula (I), wherein: R2 and R3 are independently selected from H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R, CH2—CO2H, CH2—SO2R, O—SO2R, CO2R, COR and CN, and there is optionally a double bond between C1 and C2 or C2 and C3; R6, R7, R8 and R9 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn; R11 is either H or R; Q is S, O or NH; L is a linking group, or a single bond; O is a solid support; or where one or more of R2, R3, R6, R7 and R8 are independently: H—(T)n—X—Y—A— where: X is CO, NH, S or O; T is a combinatorial unit; Y is a divalent group such that HY=R; A is O, S, NH, or a single bond and n is a positive integerType: GrantFiled: February 26, 2001Date of Patent: June 8, 2004Assignee: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Publication number: 20040092736Abstract: A compound of formula (IV): O is a solid support; L is a linking group or a single bond; X′ is selected from CO, NH, S, or O; A is O, S, NH, or a single bond; R2 and R3 are independently selected from: H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R, CH2—CO2H, CH2—SO2R, O—SO2R, CO2R, COR, CN and there is optionally a double bond between C1 and C2 or C2 and C3; R6, R7, and R9 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn; R11 is either H or R; Q is S, O or NH; R10 is a nitrogen protecting group; and Y is a divalent group such that HY═R, and other related compounds and collections of compounds.Type: ApplicationFiled: June 24, 2003Publication date: May 13, 2004Applicant: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Publication number: 20030195196Abstract: A compound with formula (I) 1Type: ApplicationFiled: March 4, 2003Publication date: October 16, 2003Applicant: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Publication number: 20030165899Abstract: The invention relates to methods for designing inhibitors of serine/threonine kinases and tyrosine kinases, particularly MAP kinases, through the use of ATP-binding site mutants of those kinases. The methods of this invention take advantage of the fact that the mutant kinases are capable of binding inhibitory compounds of other kinases with greater affinity than the corresponding wild-type kinase. The invention further relates to the mutant kinases themselves and crystallizable co-complexes of the mutant kinase and the inhibitory compound.Type: ApplicationFiled: June 12, 2002Publication date: September 4, 2003Applicant: Vertex Pharmaceuticals, Inc.Inventors: Michael Shin-San Su, Ted Fox, Keith Philip Wilson, Ursula A. Germann
-
Patent number: 6608192Abstract: A compound of formula (IV): O is a solid support; L is a linking group or a single bond; X′ is selected from CO, NH, S, or O; A is O, S, NH, or a single bond; R2 and R3 are independently selected from: H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R′, CH2—CO2H, CH2—SO2R, O—SO2R, CO2R, COR, CN and there is optionally a double bond between C1 and C2 or C2 and C3; R6, R7, and R9 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn; R11 is either H or R; Q is S, O or NH; R10 is a nitrogen protecting group; and Y is a divalent group such that HY=R, and other related compounds and collections of compounds.Type: GrantFiled: February 26, 2001Date of Patent: August 19, 2003Assignee: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Publication number: 20030120069Abstract: Compounds of the formulae Ia and Ib: 1Type: ApplicationFiled: December 12, 2001Publication date: June 26, 2003Applicant: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Patent number: 6574377Abstract: A method and apparatus for storing and retrieving images of documents, e.g. checks.Type: GrantFiled: July 1, 1999Date of Patent: June 3, 2003Assignee: The Chase Manhattan BankInventors: Thomas Cahill, Louise A. McNulty, John J. McMonagle, Richard H. Sferra, Glenn Levine, Saul Goldfisher, Philip Wilson, Vladimir Koroteyev
-
Patent number: 6562806Abstract: A compound with formula (I) where R10 is a therapeutically removable nitrogen protecting group; R2 and R3 are independently selected from: H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R, CH2—CO2H, CH2—SO2R, O—SO2—R, CO2R, COR and CN; R6, R7 and R9 are independently selected from H, R, OH, OR, halo, amino, nitro, Me3Sn; X is S, O or NH; R11 is either H or R; and where there is optionally a double bond between C1 and C2 or C2 and C3; and R8 is selected from H, R, OH, OR, halo, amino, nitro, Me3Sn, or R7 and R8 together form a group —O—(CH2)p—O—, where p is 1 or 2. Such compounds may be used in methods of ADEPT, GDEPT, NPEPT or PDT.Type: GrantFiled: February 26, 2001Date of Patent: May 13, 2003Assignee: Spirogen LimitedInventors: David Edwin Thurston, Philip Wilson Howard
-
Publication number: 20030088346Abstract: A vehicle noise, vibration and harshness analysis tool according to the present invention comprises at least one sensor, each sensing a vibration or noise and generating a signal at a frequency related to the vibration or noise. A communication link with a vehicle is included to transmit data regarding the vehicle. A microprocessor system receives the signals generated by said at least one sensor and receives the vehicle data over said communication link. The microprocessor system conducts an analysis of the received sensor signals and vehicle data and identifies a vehicle component that is likely causing a vibration or noise. The microprocessor system also identifies the possible problems with the identified vehicle component. A user interface is also included with a display. The microprocessor system causes the display to list the likely vehicle components causing the vibration or noise and the possible problems with the components.Type: ApplicationFiled: October 25, 2002Publication date: May 8, 2003Applicant: VETRONIX CORPORATIONInventors: Thomas R. Calkins, Philip Wilson
-
Patent number: 6320287Abstract: A combination of a rotor and a stator assembly, the stator assembly having a first part and a second part, the first and second parts being generally concentric, the rotor being rotatably mounted in the stator assembly, the combination further including a plurality of elongate resilient damping elements which extend generally in an axial direction, and being located between and spacing apart the first part and the second part of the stator assembly.Type: GrantFiled: March 30, 1999Date of Patent: November 20, 2001Assignee: Normalair-Garret (Holdings) LimitedInventors: Stephen Richard Watson, Malcolm Philip Wilson
-
Patent number: D452910Type: GrantFiled: December 29, 2000Date of Patent: January 8, 2002Assignee: Innovata Biomend LimitedInventors: Philip Wilson Braithwaite, Steven Graham Williams
-
Patent number: D563788Type: GrantFiled: April 6, 2007Date of Patent: March 11, 2008Assignee: JohnsonDiversey, Inc.Inventors: Kirk M. Reimann, Daniel Newman, Philip Wilson, Rajnikant Desai, Darold Faurot, Eric Weldzius