Abstract: The present description concerns a clock signal generation device (902) comprising: a microelectromechanical resonant element (504); and at least one nanoelectromechanical transduction element (512).

Abstract: The present disclosure relates generally to dosage forms (e.g., oral dosage forms) and pharmaceutical compositions comprising a pharmaceutically active agent comprising pitolisant or a pharmaceutically acceptable salt, solvate, or hydrate thereof, an alkaline agent, a delayed-release coating, and optionally one or more pharmaceutically acceptable excipients; as well as methods of using the dosage forms and pharmaceutical compositions, and methods of making the same.

Abstract: The present disclosure relates to combinations, dosage forms, and pharmaceutical formulations that comprise an active pharmaceutical ingredient, such as pitolisant, and an alkalinizing agent for improving absorption of the active pharmaceutical ingredient.

Abstract: Localization of a user device in a mixed reality environment in which the user device obtains at least one keyframe from a server, which can reside on the user device, displays at least one of the keyframes on a screen, captures by a camera an image of the environment, and obtains a localization result based on at least one feature of at least one keyframe and the image.

Abstract: The present invention relates to method for medical imaging, the method being characterized in that it comprises the implementation, by a data processor (11b) of a second server (1b), of steps of: (a) Obtaining at least one candidate pre-contrast image and a candidate contrast image respectively depicting a body part prior to and after an injection of a first dose of contrast agent, wherein said first dose is higher than a predetermined low dose, the predetermined reduced dose being lower than a predetermined standard dose; a convolutional neural network, CNN, being trained to reconstruct, from at least a pre-contrast input image and a low dose contrast input image respectively depicting a body part prior to and after an injection of said low dose of contrast agent, a standard dose contrast image depicting said body part after an injection of said standard dose of contrast agent; (b) Simulating an injection of a second dose of contrast agent which is higher than the standard dose, wherein said simulating comp

Abstract: An aircraft floor including at least one hinge connecting movable and fixed floor parts, which has a pivot axis parallel to a longitudinal direction. The floor also includes at least two beams, each including first and second beam portions secured respectively to the fixed and movable floor parts and connected together by a pivot link, and at least one rail including at least one first rail portion secured to the movable floor part and at least one second rail portion secured to the fixed floor part of the floor, extending the first rail portion.

Abstract: A structural assembly for an aircraft having pairs of main gantries distributed in the longitudinal direction, two transverse panels fixed to the front and the rear of the pairs of main gantries to together define a compartment for a landing gear of the aircraft, at least one pair of secondary gantries between the main gantries, at least one crossmembers parallel to the transverse panels and that straddles at least one secondary gantry, and, for each secondary gantry and each crossmember straddling the secondary gantry, a connecting rod mounted to be able to freely rotate, via a first end, on a lower part of the crossmember and, via a second end, on an outer lateral part of the secondary gantry. Such an arrangement reduces the vertical bulk of the structural assembly.

Abstract: The present application concerns novel benzimidazole enantiomeric derivatives, their process of preparation and their therapeutical uses as dual H1 and H4 receptor ligands.

Abstract: An aircraft including a floor positioned above a central wing box and in a front fuselage portion positioned in front of the central wing box. The floor includes at least one rail which has at least first and second rail portions and at least one articulation connecting the first and second rail portions and configured to allow a pivoting movement, about a transverse and horizontal pivot pin, between the connected first and second rail portions. By virtue of this articulation, it is possible to integrate the rails into the floor and not to position them on the floor.

Abstract: A structural assembly for an aircraft having pairs of main gantries distributed in the longitudinal direction, two transverse panels fixed to the front and the rear of the pairs of main gantries to together define a compartment for a landing gear of the aircraft, at least one pair of secondary gantries between the main gantries, at least one crossmembers parallel to the transverse panels and that straddles at least one secondary gantry, and, for each secondary gantry and each crossmember straddling the secondary gantry, a connecting rod mounted to be able to freely rotate, via a first end, on a lower part of the crossmember and, via a second end, on an outer lateral part of the secondary gantry. Such an arrangement reduces the vertical bulk of the structural assembly.

Abstract: A method for processing a 3D scene, and corresponding device, system and computer program are disclosed. In an example embodiment, the disclosed method includes: obtaining an image comprising at least a nadir view of a 3D scene, captured by at least one camera; detecting, in the image, at least one shadow cast by at least one object of the 3D scene acting as a support for the at least one camera; and determining a direction of at least one real light source from the at least one detected shadow and at least information representative of the object.

Abstract: A structural assembly for an aircraft having pairs of main gantries distributed in the longitudinal direction, two transverse panels fixed to the front and the rear of the pairs of main gantries to together define a compartment for a landing gear of the aircraft, at least one pair of secondary gantries between the main gantries, at least one crossmember parallel to the transverse panels and that straddles at least one secondary gantry, and, for each secondary gantry and each crossmember straddling the secondary gantry, a connecting rod mounted to be able to freely rotate, via a first end, on a lower part of the crossmember and, via a second end, on an outer lateral part of the secondary gantry. Such an arrangement reduces the vertical bulk of the structural assembly.

Abstract: Aspects of the disclosure relate to vehicles capable of autonomous driving. These vehicles may include seats for accommodating different numbers of passengers. In some cases, the seats may be reconfigurable. For instance, a vehicle may include a first row of seating having a first, passenger use configuration. The first row may allow a passenger to sit in a seat of the first row of seating and access user input controls for the vehicle. The first row of seating may also have a second, folded configuration where the first row is in a folded configuration and no longer usable for passenger seating. The vehicle may also have a second row of seating. When the first row of seating is in the second, folded configuration, the second row of seating may still be usable for seating and may include additional legroom for the passenger as compared to when the first row of seating is in the first passenger use configuration.

Abstract: The present invention relates to solid forms of (5S)-cyclopropyl-5-[3-[(3S)-4-(3,5-difluorophenyl)-3-methyl-piperazin-1-yl]-3 -oxo-propyl]imidazolidine-2,4-dione and to pharmaceutical preparations comprising them and methods of their manufacture, as well as the use of said solid forms or preparations for the prophylaxis and/or treatment of inflammatory conditions, muscular disease, fibrotic diseases, viral infection, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis, especially osteoarthritis.

Abstract: A transduction detection device includes a substrate, at least one movable ground relative to the substrate and a suspended stress gauge provided with a piezoresistive element which includes a first anchoring and a second anchoring, different from the first anchoring, relative to the movable ground, wherein it includes at least one thermal dissipator element thermally conductively connected: to a connection portion of the piezoresistive element located outside of the anchorings, and to a thermal discharge part.

Abstract: The present invention relates to a method for processing an inputted perfusion sequence, by means of a convolutional neural network, CNN, the method being characterized in that it comprises the implementation, by a data processor (11b) of a second server (1b), of steps of: (b) extracting, using an encoder branch of the CNN, a plurality of initial n+1-dimensional features maps representative of the inputted perfusion sequence at different scales, n?3, said CNN further comprising a decoder branch and skip connections between the encoder branch and the decoder branch, each skip connection projecting the initial n+1-dimensional features maps into initial n-dimensional feature maps; (c) generating, using said decoder branch of the CNN, a plurality of enriched n-dimensional feature maps also representative of representative of the inputted perfusion sequence at different scales, each enriched n-dimensional feature map incorporating the information from the initial n-dimensional feature maps of smaller or equal scal

Abstract: The present invention relates to a method for processing at least a pre-contrast image depicting a body part prior to an injection of contrast agent, the method being characterized in that it comprises the implementation, by a data processor (11b) of a second server (1b), of steps of: (a) Obtaining said pre-contrast image; (b) Determining candidate value(s) of at least one injection parameter of said injection of contrast agent by application of a prediction model to said pre-contrast image, such that a theoretical contrast image depicting said body part during injection of contrast agent in accordance with the determined candidate value(s) of said injection parameter(s) is expected to present a target quality level.

Abstract: A method and an apparatus for processing a 3D scene are presented. Techniques are disclosed for determining light source locations, including tracking a current viewpoint of a camera capturing object(s) in a 3D scene and determining a reference viewpoint relative to the current viewpoint of the camera. According to aspects, a light source location is determined by obtaining a registered map of real cast shadows of the object(s) from an input image captured by the camera, registered with respect to the reference viewpoint. Then, for candidates of light sources, obtaining respective maps of virtual shadows of the object(s) created with respect to the reference viewpoint, and determining the location of the light source based on the candidates of light sources with respective maps of virtual shadows that match the registered map of real cast shadows.

Abstract: A robot (20) includes a base (203, 204) and a detachable probe (205). The probe (205) includes at least one sensor of a least one type. Propulsion of the probe is provided by an ejection mechanism (204, 302) in the base. When the probe is ejected by the base, the probe captures data using its sensor(s) during its trajectory, according to an observation plan established by the base. The probe is recaptured by the base, probe data is transferred to the base, and the probe (205) is configured for a new observation.

Abstract: Estimating lighting conditions in a mixed reality scene is a challenging task. Adding shadows cast by virtual objects in the scene contributes significantly to the user experience. To this end, there is proposed, among others, a method for an autonomously movable device having a camera. The device may move to a first position in the scene and capture a first image of a shadow of the device cast by a light source. The device may move to a second position in the scene and capture a second image of a shadow of the device cast by a light source. Features of the light source may be determined at each of the first and the second positions, and a lighting model may be determined for the scene based on the determined features of the light source in the scene.