Abstract: The invention provides peptides that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the peptide not attached to the water soluble oligomer.

Abstract: One embodiment of the invention involves a model-based method of inverting electromagnetic data associated with a subsurface area that includes developing a three-dimensional electromagnetic property model of the area, and restricting changes that may be made to the model during the electromagnetic data inversion process. Other related embodiments of the inventive method are also described and claimed.

Abstract: Conjugates of a Factor VIII moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising the conjugates, methods of making the conjugates, and methods of administering compositions comprising the conjugates to a patient.

Abstract: A system, method, and computer program product are provided for handling bulk initial downloads of databases to mobile devices. Rather than straining the resources of a mobile device to recreate the database locally, a server can construct the database to the mobile device's requirements at the server by impersonating the mobile device. The server can then send the database, compressed and over an encrypted session, to the mobile device. The mobile device can then decrypt and uncompress the pages received, and then encrypt them using a local key for secure storage on a local storage device.

Abstract: The method for the model-based monitoring of a turbomachine by means of a monitoring unit which receives relevant process parameters of the turbomachine, carries out calculations on the basis of these parameters and, as a result, determines one or more state values, by means of which the state of the turbomachine can be assessed, the calculations of the state values being carried out on the basis of one or more physical models of at least one subsystem of the turbomachine, wherein the at least one subsystem is an axial bearing of the turbomachine, and the one or more state values are selected from the axial thrust force, the axial bearing load and the axial shaft attitude.

Abstract: The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.

Abstract: The present invention provides methods, compositions and kits for detecting the presence or absence of an integrated insertion polynucleotide.

Abstract: An computer program generation system (100) for creating a computer program includes: (a) a recorder module (103) capable of recording data comprising actions of a user of one or more applications; (b) a storage module (112) to store predefined portions of source code; and (c) a code generation module (105) capable of generating source code for the computer program using the data and the predefined portions of source code from the storage module (112).

Abstract: An integrated circuit structure is disclosed. The integrated circuit structure includes a first package substrate including a radiating element, the radiating element having a radiating element connection extending from the radiating element. The integrated circuit structure further includes a first chip positioned adjacent to the radiating element connection, the first chip having a first chip connection on a surface of the first chip, wherein the first chip connection forms a capacitive coupling with the radiating element connection. A method of forming an integrated circuit structure is also disclosed.

Abstract: Conjugates of a Factor VIII moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising the conjugates, methods of making the conjugates, and methods of administering compositions comprising the conjugates to a patient.

Abstract: For the present invention, a P-type thermo-electric thin-film layer and a N-type thermo-electric thin-film layer are respectively deposited on two sides of an insulating substrate. During the deposition, the P-type thermo-electric thin-film layer and the N-type thermo-electric thin-film layer are deposited and connected on the same exposed side of the insulating substrate, and then a PN junction is formed. This method makes the fabrication simplified without special process for connecting the P-type thermo-electric thin-film layer and the N-type thermo-electric thin-film layer. Due to the features of thin-film thermo-electric material, the performance of thermo-electric generator is improved. During the deposition, the P-type thermo-electric thin-film layer and the N-type thermo-electric thin-film layer are deposited and connected on the exposed side of the insulating substrate, so welding is not required in this heating surface side.

Abstract: The invention is directed to systems, methods, and apparatus for carrying out multi-stage amplification reactions, especially under fluidly closed conditions. In one aspect, methods of the invention are carried out in a fluidly closed reaction system that permits the isolation of a portion of a first (or prior) reaction mixture and its use as a sample or specimen in a second (or subsequent) reaction mixture, thereby substantially avoiding interfering effects that first reaction components may have in the second reaction if both reaction mixtures were simply combined together. In this aspect, systems, methods, and apparatus of the invention may be used with any amplification reaction that permits multiple stages of amplification based on the use of nested primers.

Abstract: Conjugates of a Factor VIII moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising the conjugates, methods of making the conjugates, and methods of administering compositions comprising the conjugates to a patient.

Abstract: The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided.

Abstract: A customer terminal is provided. The customer terminal includes a receiving module and a decryption module. The receiving module receives an encrypted digital content from a database server connected thereto. A predetermined encryption key encrypts the encrypted digital content. The decryption module decrypts the encrypted digital content utilizing hardware information from the customer terminal. A database server and a protection method are also provided to prevent an unauthorized customer terminal from copying digital contents.

Abstract: A method for parsing a text file defines a tree pattern and a plurality of character string patterns. A tree structure corresponding to the text file is determined according to the tree pattern, and the desired data are retrieved from the text file according to the character string patterns. The retrieved desired data are output into a storage system.

Abstract: Alert generation is managed. A frequency with which a performance metric satisfies a first condition is determined. It is determined whether the frequency satisfies a second condition. An alert is generated based on the determinations.

Abstract: There is provided an electronic device. The electronic device includes at least one epitaxial semiconductor layer disposed on a single crystal substrate comprised of gallium nitride having a dislocation density less than about 105 per cm2. A method of forming an electronic device is also provided. The method includes providing a single crystal substrate comprised of gallium nitride having a dislocation density less than about 105 per cm2, and homoepitaxially forming at least one semiconductor layer on the substrate.

Abstract: The present invention is directed to a method for making a tire having a foam noise damper, comprising the steps of: pressing a barrier layer onto an exposed virgin surface of a green tire innerliner to adhere the barrier layer to the virgin surface and thereby form a protected green innerliner; curing the protected green innerliner; removing the barrier layer to reveal the virgin surface; and securing a foam noise damper to the virgin surface.

Abstract: A tire carcass to be used with any type of tire is shown herein. A tire carcass includes a first ply portion, a second ply portion, each ply portion having an inner sidewall ply, an outer sidewall ply, a first end, a second end, and a bead core, a bridge portion, wherein the first ends of the ply portions are separated by the bridge portion, and at least two bridge plies, wherein the bridge plies span the bridge portion, wherein each of the bridge plies have a first end and a second end.