Abstract: Described herein are markers, conjugates, compositions and methods for hypoxia imaging, mapping, and therapy. A compound comprising bio-reductively activated (BA) arm, linker arm and a mapping click wherein BA contains one for more of substituted or unsubstituted 2/4/5-substituted nitroimidazoles, or substituted benzotriazene-1,4-dioxides, or substituted 1,2,3/1,2,4-triazoles, or substituted 1,4-benzoquinones, or a combination of two homo-or hetero BA moieties, wherein linker arm contains C1-16 alkane, alkene, alkyne, alicyclic or aromatic linkers with or without hetero atoms as in ethers, amine, esters, acid, amides, 5 and 6 membered sugar sings with the substitution as described above, both monosaccharides and disaccharides, wherein mapping click contains one of substituted or unsubstituted —N3-, CN, SCN, substituted alkynes for click chemistry.

Abstract: A portable utensil holder for providing a utensil setting for a single diner, to serve as a convenient place to place a set of dining utensils for the diner that minimizes contact between the utensils and potentially unsanitary surfaces, for a healthier and more convenient dining experience. The utensil holder includes a set of recesses formed thereon, each shaped to accommodate a utensil of a corresponding type. The recesses are oriented parallel to each other and separated by intervening side walls, giving each utensil its own dedicated spot within the utensil holder. The recesses are connected by a groove oriented orthogonally to the recesses, allowing for utensils to be placed and retrieved while minimizing contact of the utensil head with potentially unsanitary surfaces.

Abstract: A digital steganography system comprises a message sender in electronic communication with a message receiver through a social media platform. The message sender uses a compute device configured to conceal a secret digital message in the semantic components of a digitally synthesized image which is uploaded onto the social media platform and published in a social media post. As part of the message encoding process, the compute device for the message sender coverts the digital message into binary code, applies encryption and error-correction algorithms, and then implements image synthetization operations to yield the digitally synthesized image. The message receiver is provided with a compute device configured to identify the social media post, automatically download the synthesized image, and apply an inverse set of the image synthetization operations to yield binary code which is subsequently decoded and decrypted in order to extract the original covert message.

Abstract: Methods and apparatuses for controlling a satellite antenna based on its motion are disclosed. In some embodiments, the method comprises determining a motion state of an antenna for communication with a satellite, determining a motion profile for the antenna based on the motion state, and controlling the antenna based on the motion profile.

Abstract: Described herein are bioreductively-activated compounds, their prodrugs, radiopharmaceuticals, the compositions, and their application in multimodal theranostic management of hypoxia diseases including cancer.

Abstract: A nanoparticle includes a nanocarrier encapsulating a nanoscintillator capable of emitting light upon exposure to radiation; a photosensitizer capable of absorbing the light from the nanoscintillator to generate singlet oxygen species; and optionally, one or more diagnostic agents, therapeutic agents, or a combination thereof.

Abstract: Described herein are bioreductively-activated compounds, their prodrugs, radiopharmaceuticals, the compositions, and their application in multimodal theranostic management of hypoxia diseases including cancer.

Abstract: Described herein are markers, conjugates, compositions and methods for hypoxia imaging, mapping, and therapy. A compound comprising bio-reductively activated (BA) arm, linker arm and a mapping click wherein BA contains one for more of substituted or unsubstituted 2/4/5-substituted nitroimidazoles, or substituted benzotriazene-1,4-dioxides, or substituted 1,2,3/1,2,4-triazoles, or substituted 1,4-benzoquinones, or a combination of two homo-or hetero BA moieties, wherein linker arm contains C1-16 alkane, alkene, alkyne, alicyclic or aromatic linkers with or without hetero atoms as in ethers, amine, esters, acid, amides, 5 and 6 membered sugar sings with the substitution as described above, both monosaccharides and disaccharides, wherein mapping click contains one of substituted or unsubstituted —N3-, CN, SCN, substituted alkynes for click chemistry.

Abstract: A method for localizing for GPS denied environments is provided with a plurality of broadcasting transmitters and a software-defined radio (SDR). A pre-processing stage and a query phase is executed for localizing an unknown location. The results from the preprocessing stage are made available to the query stage. A simulated power spectrum is computed for a region of interest during the pre-processing phase via the plurality of broadcasting transmitters. A transmitter location, a radius of influence, and a power contour plot of each of the plurality of broadcasting transmitters are used for computing the simulated power spectrum. Next, a peak-finding process, a filtering process, and a localization process is executed during the query phase in order to identify the unknown location.

Abstract: Techniques for providing information about large data sets may be provided. For example, a summary of the data sets and of patterns between the data sets may be presented. Traffic associated with a network-based resource that includes a number of documents may be an example of large data sets. The traffic may be analyzed and traffic patterns may be determined. A structure may be generated based on the traffic patterns and may use nodes to represent the documents. Further, a visualization of the structure may be presented. The visualization may include recursive clusters of the nodes, where the clusters may be labeled based on the respective clustered nodes.

Abstract: Methods and systems are provided for assessing compatibility between forms of medication in a clinical setting. Generally, a medical order for a patient is received, which specifies a task with an initial form of a medical agent to be administered to the patient. When a clinician attempts to administer the medical agent to the patient, a current form of the medical agent is received from a scanning device, for example. As such, it may be determined whether the current form is compatible with the initial form. When it is determined that the current form is not compatible with the initial form, an error may be generated and issued in an effort to prevent administration of the current form to the patient.

Abstract: A method for localizing for GPS denied environments is provided with a plurality of broadcasting transmitters and a software-defined radio (SDR). A pre-processing stage and a query phase is executed for localizing an unknown location. The results from the preprocessing stage are made available to the query stage. A simulated power spectrum is computed for a region of interest during the pre-processing phase via the plurality of broadcasting transmitters. A transmitter location, a radius of influence, and a power contour plot of each of the plurality of broadcasting transmitters are used for computing the simulated power spectrum. Next, a peak-finding process, a filtering process, and a localization process is executed during the query phase in order to identify the unknown location.

Abstract: An apparatus, program product and method for managing access to a secure, encrypted webserver. A user computer may communicate through a cloud server with the secure webserver via an End-To-End encrypted connection. The webserver being able to run applications, receive and distribute data with similarly secured webservers and receive and distribute data between the webserver and the client computer. The End-To-End Encrypted connection may remain open until the client computer disconnects and the identity of the user is authenticated by a cloud server.

Abstract: Techniques for providing information about large data sets may be provided. For example, a summary of the data sets and of patterns between the data sets may be presented. Traffic associated with a network-based resource that includes a number of documents may be an example of large data sets. The traffic may be analyzed and traffic patterns may be determined. A structure may be generated based on the traffic patterns and may use nodes to represent the documents. Further, a visualization of the structure may be presented. The visualization may include recursive clusters of the nodes, where the clusters may be labeled based on the respective clustered nodes.

Abstract: Provided in the following specification are precursors or synthons that are useful for the synthesis of various arabinose based chemical and radiochemical derivatives of nitroimidazole-containing azomycin arabinosides, such as radioiodinated 1-#-D-(5-deoxy-5-[I*]-iodoarabinofuranosyl)-2-nitroimidazole (*IAZA), and radiofluorinated 1-#-D-(5-deoxy-5-[18F]-iodoarabinofuranosyl)-2-nitroimidazole (18FAZA). Such compounds are useful in imaging, therapy, or radiotherapy. Further, various syntheses of said precursors/synthons and the incorporation of said precursors/synthons into kits is provided. The precursors/synthons provided herein allow for an improved and facile manufacturing process for nitroimidazole-containing azomycin arabinosides.

Abstract: A system and method of aggregating and predicting stock ranking stocks. The novel system and method uses a neighborhood model to aggregate a plurality of “neighboring” or related stocks having similar pricing trends. The system and method then uses a ranking optimization method to predict the ranking of each stock based on percentage change in price. The current invention facilitates investors trading by using a novel methodology to predict stock rankings and providing a neighborhood of related stocks, while having an easy-to-use interface.

Abstract: A system and method of aggregating and predicting stock ranking stocks. The novel system and method uses a neighborhood model to aggregate a plurality of “neighboring” or related stocks having similar pricing trends. The system and method then uses a ranking optimization method to predict the ranking of each stock based on percentage change in price. The current invention facilitates investors trading by using a novel methodology to predict stock rankings and providing a neighborhood of related stocks, while having an easy-to-use interface.

Abstract: Provided in the following specification are precursors or synthons that are useful for the synthesis of various arabinose based chemical and radiochemical derivatives of nitroimidazole-containing azomycin arabinosides, such as radioiodinated 1-#-D-(5-deoxy-5-[I*]-iodoarabinofuranosyl)-2-nitroimidazole (*IAZA), and radiofluorinated 1-#-D-(5-deoxy-5-[18F]-iodoarabinofuranosyl)-2-nitroimidazole (18FAZA). Such compounds are useful in imaging, therapy, or radiotherapy. Further, various syntheses of said precursors/synthons and the incorporation of said precursors/synthons into kits is provided. The precursors/synthons provided herein allow for an improved and facile manufacturing process for nitroimidazole-containing azomycin arabinosides.

Abstract: The present invention provides for compounds suitable for therapeutic treatment of hypoxic tissues, particularly for application in radiotherapy, chemosensitization, radiosensitization. The present invention further provides for compounds suitable for radioimaging of hypoxic cells.