Abstract: This invention relates to thermoresponsive hydrogels. Particularly, the invention relates to a thermoresponsive hydrogel comprising copolymer polyethylene glycol (PEG)-polycaprolactone (PCL)-polyethylene glycol (PEG) and polypropylene fumerate (PPF). The thermoresponsive hydrogel may further comprise a poloxamer, particularly Pluronic F-127. The invention extends to a method of manufacturing thermoresponsive hydrogels, also extends to an ink for a three dimensional (3D) printer including the thermoresponsive hydrogels. The invention further extends to a thermoresponsive hydrogel for use in the treatment of a bone injury and/or a bone defect, and/or to a method of treating a bone injury and/or a bone defect. The thermoresponsive hydrogels may include dispersed therein an active pharmaceutical ingredient (API), preferably an API falling in the Biopharmaceutics Classification System (BCS) class II, further preferably a statin type drug, most preferably simvastatin.

Abstract: Systems and methods are provided for assigning and associating resources in a cloud computing environment. Virtual machines in the cloud computing environment can be assigned or associated with pools corresponding to users as dedicated, standby, or preemptible machines. The various states provide users with the ability to reserve a desired level of resources while also allowing the operator of the cloud computing environment to increase resource utilization.

Abstract: A soft card provisioning application is instantiated on a device with wireless communications capabilities. A card number for a soft card desired to be provisioned on the device is obtained from a user of the device. An issuer identification number retrieved from the card number is communicated to a provisioning configuration server over an air interface. A provisioning issuer server network address is obtained from the provisioning configuration server based on the issuer identification number. Card issuer specific challenges are presented to the user, and the user's responses to the challenges are received. The challenge responses are communicated to the provisioning issuer server. Soft card image data and personalization data, where the personalization data includes personalized embossed and pre-printed data, are received from the provisioning issuer server over the air interface. The soft card is provisioned for use on the device based on the data received over the air interface.

Abstract: The invention provides compounds of formula (I): and salts thereof wherein R1-R5 have any of the meanings described in the specification. The compounds are useful for treating bacterial infections (e.g. tuberculosis).

Abstract: A method for optimizing power of a ranging sequence includes counting at least one cycle of a first clock during a Crystal Oscillator (XO)-mode to generate a first cycle count. A second clock is activated at an end of the XO-mode. The first cycle count is converted into a fractional correction value by multiplying the first cycle count by a ratio of a second period of the second clock divided by a first period of the first clock. A first alignment of the first clock to the second clock is determined at a beginning of the XO-mode. A second alignment of the first clock to the second clock is determined at the end of the XO-mode. An adjusted cycle count is determined by summating the fractional correction value with a summation of the first alignment and the second alignment divided by the first period.

Abstract: An apparatus is provided which comprises: a first network interface (NI) to receive data from a source; a second NI coupled to a target; and a circuitry to generate a sequence of source timestamps and a sequence of target timestamps, wherein the first NI is to receive the sequence of source timestamps, and associate a first source timestamp of the sequence of source timestamps with the data, and wherein the second NI is to receive: the data with the first source timestamp from the first NI and the sequence of target timestamps from the circuitry, the second NI to generate a timestamp for the data, based at least in part on the first source timestamp and a first target timestamp of the sequence of target timestamps.

Abstract: A method for compensation network design in a power converter design system is provided that includes computing optimal values for compensation components in a compensation network based on a plurality of loop specifications comprising crossover frequency (Fco), phase margin (PM), Gain Margin (GM), and low frequency gain (LFG), and applying changes to a power converter design comprising the compensation network based on the optimal values.

Abstract: Uninterruptible power supplies (UPSs) are provided including a processor and a voltage sensor circuit in communication with the processor. The voltage sensor circuit is configured to sense a center point voltage (CPV) of a battery module associated with the UPS and provide the sensed CPV to the processor. The processor is configured to receive the sensed CPV of the battery module, determine if the CPV is less than a predetermined voltage and turn off all battery chargers associated with the battery module if the CPV is determined to be less than the predetermined voltage.

Abstract: A caliper pig for detecting geometrical deformation of a pipeline is disclosed. The caliper pig includes a body and a first sensor arm assembly. The first sensor arm assembly includes a primary caliper sensor ring adapted to be mounted on the body. Further, the first sensor arm assembly includes a plurality of sensor arms adapted circumferentially distributed on the primary caliper sensor ring. Each of the plurality of sensor arms includes a sensing arm adapted to be in contact with an internal surface of the pipeline and a pair of magnets adapted to rotate along the sensing arm. Each of the plurality of sensor arms includes a sensing unit configured to detect a change in magnetic field based on the movement of the sensing arm. The sensing unit is configured to generate an output indicative of an angle of deflection of the sensing arm while traversing on the internal surface of the pipeline.

Abstract: The present disclosure relates to pharmaceutical salts and polymorphic forms of forms of pyrimidine derivatives that have inhibitory activities against mutant epidermal growth factor receptor (EGFR). The present disclosure further relates to the processes for the preparation of the pyrimidine derivatives and to the pharmaceutical salts and the polymorphic forms of the pyrimidine derivatives.

Abstract: The present technology discloses methods and systems for receiving a security profile request from an integrity verifier, the request including a nonce; requesting, from a trusted platform module, a new nonce, wherein the new nonce is generated at least in part by the nonce and a current timestamp from a clock in the trusted platform module; receiving, from the trusted platform module, the new nonce; requesting, from a cryptoprocessor, a set of platform configuration registers; receiving, from the cryptoprocessor, the set of platform configuration registers; and sending a response to the integrity verifier, the response including the new nonce and the set of platform configuration registers to verify a security status of the trusted platform module and the cryptoprocessor.

Abstract: A method includes receiving a circuit design including a plurality of components associated with a plurality of component parameters. The method further includes adjusting a value of a particular component parameter of the plurality of component parameters based on a tolerance to generate a modified plurality of component parameters. The method further includes determining, based on inputting the modified plurality of component parameters into a circuit calculator, that an operating value of the circuit design is sensitive to the particular component parameter. The method further includes selecting a simulation of the circuit design to perform based on the particular component parameter. The method further includes performing the simulation to determine whether the circuit design supports one or more design limits.

Abstract: Methods, systems, and devices for multi-subscription management are described. A user equipment (UE) supporting a dual-subscriber identify module (SIM) configuration may identify a message to disable a subscription associated with a first SIM of a dual-SIM universal SIM (USIM) card. Disabling the first SIM may include powering down a modem stack associated with the first SIM while maintaining power to the first SIM. The UE may configure a SIM toolkit manager associated with a SIM toolkit for the first SIM to a disabled state based at least in part on the message. The UE may then indicate to the first SIM that the SIM toolkit manager is in the disabled state.

Abstract: A mobile device may be configured to determine, in a secure portion of the mobile device, whether a non-volatile indication (e.g., a fuse or non-volatile bit or flag) allocated to lender binding has been set. A mobile device processor may query a payment server associated with a lender of the mobile device to determine a next payment due date in response to determining that the non-volatile indication allocated to lender binding has been set, and select an operating mode for the mobile device based on a difference between the next payment due date and the current date.

Abstract: Certain aspects of the present disclosure provide techniques for resource block assignment and packet collision avoidance in sidelink communications. A method that may be performed by a first user equipment (UE) generally includes determining at least a first set of resources for a second UE overlaps at least a second set of resources for a third UE. The method generally includes broadcasting an indication of overlapping resources to at least the second UE and the third UE.

Abstract: A computer-readable medium comprises instructions which, upon execution by a node in a multi-node data processing system, enable the node to serve as a first leader node by receiving system log data from multiple compute nodes in a first cluster of the multi-node data processing system, and by saving the system log data in shared storage that is also used by second and third leader nodes to save system log data for compute nodes in second and third clusters of the multi-node data processing system. The instructions further enable the node to respond to failure of either of the second and third leader nodes by automatically assuming system logging duties for the compute nodes in the cluster that was associated with the failed leader node. The instructions may also enable the node to serve as a console bridge and to save console log data in the shared storage.

Abstract: A method is provided to anonymize the media access control (MAC) address of a client device. The method involves generating a plurality of media access control (MAC) addresses for use by a client device in a network. Policies are defined that determine which one of the plurality of MAC addresses is to be used by the client device. The plurality of MAC addresses allocated for use by the client device are registered with a management entity in the network.

Abstract: A method includes inducing a first quantity of a feed fluid (28) to flow along a first direction (72) from a bioreactor (12) to a tangential flow filter (16) to separate the first quantity of the feed fluid (28) into a permeate fluid (42) and a retentate fluid (48). Further, the control unit (66) is operated to control at least one feed flow control device (24, 26) to inhibit the flow of first quantity of the feed fluid (28). Furthermore, the control unit (66) is operated to control the at least one feed flow control device (24, 26) to direct at least one of further flow of a second quantity of the feed fluid (28) from the bioreactor (12), a portion of the permeate fluid (42), and a portion of a nutrient fluid, along a second direction (74) opposite to the first direction (72) via the tangential flow filter (16).

Abstract: Provided are techniques for tracking a tagged object using a thermostat. The techniques include utilizing a controller that includes a display, wherein the controller is located in a thermostat and is configured to receive a scan request. The techniques also include a tag that is coupled to an object, where the tag is configured to transmit a beacon, and one or more sensors are configured to detect the beacon and transmit data associated with the tag to the controller, wherein each of the one or more sensors are located in one or more zones of a structure.

Abstract: A cloud security method implement web security at the application level by monitoring network traffic and detecting cloud activities related to web applications, and then classifying the detected cloud activities to map certain security-related cloud activities into activity categories to enable security policy to be applied. The application-level cloud security method enables policy enforcement rules to be established for cloud activity categories. The security policies are then applied based on activity categories.