Patents by Inventor Qian Shi

Qian Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6624317
    Abstract: Compounds according to formula I: T1—L—T2   (I), wherein T1 is a taxoid group, preferably of Formula II: wherein R1 is C6H5; R2 is O; L is a linking group; and T2 is a substituent selected from the group consisting of epipodophyllotoxin, amsacrine, ellipticine, anthracycline antibiotic, mitoxantrone, and colchicine groups, and pharmaceutically acceptable salts thereof, are provided herein. The compounds are useful in, among other things, treating tumors or cancer in subjects in need thereof, inducing cellular differentiation, and inhibiting cellular mitosis.
    Type: Grant
    Filed: September 25, 2000
    Date of Patent: September 23, 2003
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Kuo-Hsiung Lee, Qian Shi, Kenneth F. Bastow, Hui-Kang Wang
  • Patent number: 6265571
    Abstract: A process for purifying the bacterial fermentation product ivermectin, particularly for use as a reference standard compound in a governmental regulatory approval process. The process includes the use of reversed-phase flash column chromatography coupled with gradient elution. An exemplary eluent mixture includes acetonitrile, methanol and water.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: July 24, 2001
    Assignees: Magellan Laboratories, Inc., Blue Ridge Pharmaceuticals
    Inventors: Qian Shi, John A. Hill
  • Patent number: 6054659
    Abstract: Structures and fabrication methods of micromachined all-metal relays on silicon chips are described. The relay comprises a copper blade, electroformed into the lithographically patterned areas, with suitable dimensions of 1 mm.times.2 mm.times.0.01 mm (width.times.length.times.thickness) and a plurality of longitudinal slots to facilitate fabrication of the blade. The relay is actuated by electrostatic force, and no conduction current is required to hold the relay at either "on" or "off" state. Preferably, the relay is used in combination with a suitable arc suppression circuit.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: April 25, 2000
    Assignee: General Motors Corporation
    Inventors: Han-Sheng Lee, Chi Hung Leung, Qian Shi, Shih-Chia Chang, David Byrum Hicks, Samuel Lorincz, Iulian Nedelescu