Abstract: Modified viruses encoding transporter proteins and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses also can be used in diagnostic methods, such detection and imaging of tumors. The viruses also can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including as anti-tumor agents.

Abstract: An application programming interface and related system is presented for a middleware communication space that provides asynchronous message delivery service for partially connected mobile ad hoc networks. Embodiments of the present invention use mobile devices to bridge separated islands of networks and store and propagate messages. The system and software architecture supports methods for messaging caching, transferring and routing. More specifically, embodiments provide methods and systems that extend a communication space concept into a distributed environment and combine it with the standard Web Services technologies, i.e, SOAP, and WS series protocols. The communication space provides an extension of Web Services to mobile ad hoc networks and provides asynchronous message caching, transferring and routing.

Abstract: A system is presented for providing a middleware communication space that provides asynchronous message delivery service for partially connected mobile ad hoc networks. Embodiments of the present invention use mobile devices to bridge separated islands of networks and store and propagate messages. The system and software architecture supports methods for messaging caching, transferring and routing. More specifically, embodiments provide methods and systems that extend a communication space concept into a distributed environment and combine it with the standard Web Services technologies, i.e, SOAP, and WS series protocols. The communication space provides an extension of Web Services to mobile ad hoc networks and provides asynchronous message caching, transferring and routing.

Abstract: Modified or attenuated viruses and methods for preparing the modified viruses and modulating attenuation are provided. Vaccines that contain the viruses are provided. The viruses can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including as anti-tumor agents. The viruses also can be used in diagnostic methods.

Abstract: The present invention discloses the usage of Poly-3-hydroxybutyrates P(3HB) in preparation of ?-lactam compounds and the method for the preparation of ?-lactam compounds of formula (I) using Poly-3-hydroxybutyrates P(3HB) as followed: wherein: R is R1, R2, R3 are lower linear or branched C1-C4 alkyl. It is convenient to synthesize the said compound of formula (I) with the present method. Compared with the previous ones, the present method has less steps and higher yields.

Abstract: A system and method for improved vertical handoff between different types of wireless network. Network allocation vector occupation and packet collision probability are used as quality of service measures, enabling vertical handoffs to be delayed until actually beneficial to quality of service. Improved wireless network cell boundary detection in vertical handoff scenarios is achieved with a Fourier-based technique in conjunction with an adaptively determined minimum operating signal strength threshold. Improved wireless network cell boundary detection enables vertical handoffs from high quality of service networks to be delayed as long as possible. Together, practical wireless network quality of service measures and improved detection of wireless network cell boundaries in vertical handoff scenarios reduce the rate of unnecessary vertical handoff resulting in higher overall quality of service experienced by a mobile computing device roaming between wireless network types.

Abstract: Modified viruses and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including as anti-tumor agents. The viruses also can be used in diagnostic methods.

Abstract: A method and system is presented for path discovery and asynchronous message transfer in a partially connected middleware communication space comprising mobile ad hoc networks. Embodiments of the present invention use mobile devices to bridge separated islands of networks and store and propagate messages. The system and software architecture supports methods for routing, messaging caching, and transferring. More specifically, embodiments provide methods and systems that extend a communication space concept into a distributed environment and combine it with the standard Web Services technologies, i.e., SOAP, and WS series protocols. The communication space provides an extension of Web Services to mobile ad hoc networks and provides asynchronous message caching, transferring and routing.

Abstract: Methods and systems for providing random access of structured media content are described. One aspect provides a novel file structure or “Vfile”, and method of using the same, for organizing and managing portions of a structured media content file that are or can be downloaded from a content provider such as a multimedia content server. The Vfile is configured to emulate a server file structure that a server uses to store structured media content files. The Vfile is established at a client location when a client accesses a structured media content file and is used to buffer and cache structured media content file portions. In addition, the Vfile includes one or more media management tags. The tags are used by the client to manage a cache of structured media content file portions that are downloaded from the server.

Abstract: A framework and method for quality of service (QoS) aware resource discovery in mobile ad hoc networks are presented. Self-organized discovery agents manage the directory information that describes the network resources available for use by clients. In one embodiment, hash indexing of available resources is utilized. The discovery agents also partition the network into domains and collect intra- and inter-domain QoS information. This information is used to allow clients to select appropriate resource providers. This framework and method has low discovery latency and cost in terms of the number of packets for each resource discovery query.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: A system for content (e.g., streaming media) is presented comprising a server, to provide media content on request through a wireline network, coupled to a wireless host through a network gateway. The network gateway establishes a communication channel from the server to the wireless host through both a wireline network and a wireless network, wherein the communication channel includes a transport layer protocol with control parameters for network elements of each of the wireline network and the wireless network. This abstract itself is not intended to limit the scope of this patent. The scope of the present invention is pointed out in the appending claims.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: A method of forming a CBI CC-1065 analog utilizes NH2 as a starting material, where R3 is H or alkyl and R6 is H, substituted or unsubstituted lower alkyl, cyano, or alkoxy. Intermediates (I) are used and are claimed.

Abstract: A resource allocation of multiple compressed AV streams delivered over the Internet is disclosed that achieves end-to-end optimal quality through a multimedia streaming TCP-friendly transport (MSTFP) protocol that adaptively estimates the network bandwidth while smoothing the sending rate. Resources allocated dynamically according to a media encoding distortion and network degradation algorithm. A scheme is also disclosed for dynamically estimating the available network bandwidth for streaming of objects, such as MPEG4 multiple video objects, in conjunction with the MSTFP protocol. The scheme can account for packet-loss rates to minimize end-to-end distortion for media delivery.

Abstract: A network emulator provides both per-connection and non-connection-based emulation. The emulator includes a host computer, and a kernel-mode emulator driver and user-mode application component running on the host computer. The application component supplies configuration parameters to the driver. The driver includes a packet filter list that filters a captured packet, a virtual network link that receives the packet from the packet filter list, a link group list that applies an emulation procedure to the packet, a timer management component that manages a timer associated with the emulation procedure, and a packet dispatcher component that sends out the packet. A connection pool component facilitates per-connection emulation.

Abstract: A system and method for improved vertical handoff between different types of wireless network. Network allocation vector occupation and packet collision probability are used as quality of service measures, enabling vertical handoffs to be delayed until actually beneficial to quality of service. Improved wireless network cell boundary detection in vertical handoff scenarios is achieved with a Fourier-based technique in conjunction with an adaptively determined minimum operating signal strength threshold. Improved wireless network cell boundary detection enables vertical handoffs from high quality of service networks to be delayed as long as possible. Together, practical wireless network quality of service measures and improved detection of wireless network cell boundaries in vertical handoff scenarios reduce the rate of unnecessary vertical handoff resulting in higher overall quality of service experienced by a mobile computing device roaming between wireless network types.

Abstract: A fuel-fired water heater has a single pass condensing-type heat exchanger disposed within its water storage tank portion. The heat exchanger includes a primary non-condensing portion defined by a combustion chamber positioned in an upper interior portion of the tank and having a spaced series of vertical tubes depending therefrom. A secondary condensing portion of the heat exchanger is defined by a plenum having a top side connected to the bottom ends of the vertical tubes, and a bottom side from which a downwardly coiled flue tube depends. A fuel burner generates hot combustion gases that are sequentially flowed into the combustion chamber and then downwardly through the balance of the heat exchanger in a single pass.

Abstract: A method and system for emulating a network bandwidth condition includes maintaining a queue for holding packets that are received, maintaining a virtual time that is updated whenever a packet timer is scheduled, and, for a selected packet waiting in the queue, calculating a timer expiration time based on the virtual time. A bandwidth emulation module is controlled by an emulator link that comprises a virtual network link to which a first computer is connected. One or more computers may be linked to the first computer.

Abstract: A spurious timeout (STO) response allows a sending device to conservatively adjust congestion state parameters and maintain the packet flow, after detection of the STO. Since occurrence of an STO may be accompanied by data loss, the STO response couples the spurious timeout and the loss event by maintaining a value of previously available bandwidth and increasing a limit that a sending host can send based on a pattern of returned acknowledgements. In particular, the limit is increased by the maximum size of a data segment that the sending host can send each time an acknowledgement is received from the receiving host indicating a successful transmission of a data packet. Thus, a positive data flow may be maintained conservatively while avoiding further packet losses and an unnecessary re-transmission of data packets that may have been successfully received by the receiving host.