Abstract: A middle layer network protocol enhancement, virtual connectivity (VC) makes the network attachment point changes of local and remote peers transparent to applications that use network services. A virtual connectivity module local to each peer translates communication connection parameters from apparent to real and vice versa, as well as sending and receiving secure connection updates directly to and from peers. Unlike Mobile IP, no routing infrastructure modifications are required. A subscribe-notify service provides connection update notifications when direct peer-to-peer connection updates are not possible, for example, when two communicating peers move simultaneously or when the moving peer is communicating with a peer behind network address translation (NAT). Methods for detecting these conditions are disclosed, as is a virtual connectivity protocol and virtual connectivity module architecture.

Abstract: Therapeutic methods and microorganisms therefor are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proferating proliferating tissues, particularly tumors, to produce selected proteins and other products. Vaccines containing the microorganisms are provided. Combinations of the microorganisms and anti-cancer agents and uses thereof for treating cancer also are provided.

Abstract: A network device for accelerating internet small computer systems interface (iSCSI) packet processing is described, which includes a host and a network card. The host includes an online command descriptor block queue, an iSCSI host manager, and an SCSI module. SCSI commands in a CDB are processed through these modules. The network card includes an LLP module and a microprocessor. Through a protocol data unit descriptor, a PDU generator and an iSCSI network card manager in the microprocessor, protocol data units in network packets can be resolved in advance, so that the host can concentrate on executing SCSI commands, thereby accelerating the network packet processing efficiency of the network device.

Abstract: Wireless network interference is mitigated with client devices having wireless network interference mitigation logic and/or utilizing a usable bandwidth channel quality metric. In a described example implementation, a client device includes wireless network interference mitigation logic that monitors at least one channel condition of a wireless network and participates in a wireless network interference mitigation procedure based on the at least one channel condition. In another described example implementation, a usable bandwidth of a wireless channel is ascertained with respect to a native network, the usable bandwidth reflecting a difference between (i) a total channel capacity of the wireless channel and (ii) a portion of the total channel capacity that is consumed by wireless communications of one or more foreign networks. By way of example only, the at least one channel condition may be usable bandwidth. The wireless network interference mitigation logic may also be employed in non-client devices.

Abstract: The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.

Abstract: The present disclosure provides drug-ligand conjugates that are potent cytotoxins and include a linker between the drug and ligand where the linker has a single amino acid. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.

Abstract: A peer-to-peer (P2P) probing/network quality of service (QoS) analysis system utilizes a UDP-based probing tool for determining latency, bandwidth, and packet loss ratio between peers in a network. The probing tool enables network QoS probing between peers that connect through a network address translator. The list of peers to probe is provided by a connection server based on prior probe results and an estimate of the network condition. The list includes those peers which are predicted to have the best QoS with the requesting peer. Once the list is obtained, the requesting peer probes the actual QoS to each peer on the list, and returns these results to the connection server. P2P probing in parallel using a modified packet-pair scheme is utilized. If anomalous results are obtained, a hop-by-hop probing scheme is utilized to determine the QoS of each link. In such a scheme, differential destination measurement is utilized.

Abstract: Therapeutic methods and microorganisms therefor are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proferating proliferating tissues, particularly tumors, to produce selected proteins and other products. Vaccines containing the microorganisms are provided. Combinations of the microorganisms and anti-cancer agents and uses thereof for treating cancer also are provided.

Abstract: A method and system for encoding a mark-up language document is provided, in which, the structure of the mark-up language document is condensed by removing those parts of the structure that are fixed, and by expressing the variable parts of the structure in terms of whether or how often they occur. A template that specifies which parts of the structure are fixed and which parts are variable may be provided to both the device that is transmitting the mark-up language document and the device that is receiving the mark-up language document.

Abstract: Therapeutic methods and microorganisms therefor are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proliferating tissues, particularly tumors, to produce selected proteins and other products. Vaccines containing the microorganisms are provided. Combinations of the microorganisms and anti-cancer agents and uses thereof for treating cancer also are provided.

Abstract: The routing of traffic in wireless networks is performed in accordance with a routing metric. The routing metric can reflect the effects of future self-traffic of a forthcoming communication flow. In a described implementation, a routing decision is made for a forthcoming communication flow that is to propagate over multiple nodes of a multi-hop wireless network. The routing decision is based on at least one predicted effect on the wireless network from self-traffic of the forthcoming communication flow.

Abstract: Therapeutic methods and microorganisms therefor are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proferating proliferating tissues, particularly tumors, to produce selected proteins and other products. Vaccines containing the microorganisms are provided. Combinations of the microorganisms and anti-cancer agents and uses thereof for treating cancer also are provided.

Abstract: Systems and methods for compressing markup language data, such as XML data, are provided that utilize a finite state machine (FSM), which is representative of an XML schema, and a rule file. Information defined in an XML schema is abstracted into a finite state machine (FSM). The rule file ensures that a compressor and de-compressor have consistent FSMs when the compressor and de-compressor for XML data are not in the same location, such as is generally the case for Web Services scenarios or other client/server scenarios. With the rule file, FSMs can thus be be easily stored, transmitted and updated.

Abstract: In view of the foregoing, the present invention provides a unified software framework or architecture for distributed coordination of wireless devices and radios, referred to as Layer 2.5 Software MAC (or ‘SoftMAC’), which resides between the standard 802.11 MAC layer (Layer 2) and IP layer (Layer 3) to regulate and control the amount of traffic (both real-time and “best effort”) delivered to 802.11 MAC DCF interfaces. The software based design can be ported to different OS platforms and systems and is capable of handling new hardware interfaces and MAC mechanisms (e.g., 802.11e) with only a software upgrade. The invention thus provides a natural way to make end systems support coordination of different radios of device(s), achieving better performance. Advantages of the 2.5 layer software MAC in accordance with the invention include: (a) there are no hardware constraints; (b) heterogeneous wireless/radio support is provided at the 2.

Abstract: A method and system for controlling an ultrasound system are provided. The method includes processing image data received from an ultrasound system to obtain a time gain compensation correction curve, wherein the image data is internally time gain compensated. The method further includes processing the image data using the time gain compensation correction curve and user inputs parameters. The user input parameters include at least one of a user defined time gain compensation parameter and a user defined dynamic range parameter.

Abstract: A method provides differentiated quality of service (QoS) by providing adaptive updates to media access control (MAC) layer parameters on a distributed basis. The method includes calculating a failure probability for a transmission over the network, determining a target value for determining a contention window according to a mapped function of the failure probability, and altering the contention window according to a scaling function of the target value. The mapped function and the scaling can provide QoS differentiation. A wireless device ensures fairness in a wireless time slotted network and includes a network interface card (NIC), a network driver interface, a network monitor, a statistics engine, and an adaptive parameter engine for determining a target value for determining a contention window according to a mapped function of the one or more probabilities to enable an alteration of the contention window and provide new parameters for the MAC layer.

Abstract: A method provides differentiated quality of service (QoS) by providing adaptive updates to media access control (MAC) layer parameters on a distributed basis. The method includes calculating a failure probability for a transmission over the network, determining a target value for determining a contention window according to a mapped function of the failure probability, and altering the contention window according to a scaling function of the target value. The mapped function and the scaling can provide QoS differentiation. A wireless device ensures fairness in a wireless time slotted network and includes a network interface card (NIC), a network driver interface, a network monitor, a statistics engine, and an adaptive parameter engine for determining a target value for determining a contention window according to a mapped function of the one or more probabilities to enable an alteration of the contention window and provide new parameters for the MAC layer.

Abstract: Therapeutic methods and microorganisms therefor are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proliferating tissues, particularly tumors, to produce selected proteins and other products. Vaccines containing the microorganisms are provided. Combinations of the microorganisms and anti-cancer agents and uses thereof for treating cancer also are provided.

Abstract: Therapeutic methods and microorganisms therefore are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proliferating tissues, particularly tumors, to produce selected proteins and other products. Methods for making tumor specific antibodies and also methods of making gene products encoded by the microorganism as well as antibodies reactive therewith are provided.