Patents by Inventor Qiang Fan

Qiang Fan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of enhancing lysosomal alpha-Galactosidase A
    Publication number: 20140206718
    Abstract: A method of enhancing the activity of lysosomal ?-Galactosidase A (?-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.
    Type: Application
    Filed: December 20, 2013
    Publication date: July 24, 2014
    Applicant: Mount Sinai School of Medicine of New York University
    Inventors: Jian-Qiang Fan, Satoshi Ishii
  • Methods for treating obstructive sleep apnea
    Patent number: 8753327
    Abstract: The present invention relates to methods for treating obstructive sleep apnea (OSA), alleviating a negative OSA symptom, reducing snoring, or improving quality of life in a subject, comprising administering to the subject an effective amount of a pharmaceutical composition comprising pyridostigmine before sleep. Also provided are related medicaments as well as methods for preparing the medicaments.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: June 17, 2014
    Assignee: Pfantastic Medical Research Institute, LLC
    Inventor: Jian-Qiang Fan
  • Method and Apparatus for Controlling Terminal, and Terminal
    Publication number: 20140108491
    Abstract: The present invention provides a method and an apparatus for controlling a terminal, and a terminal. The method includes: receiving a terminal identity sent by a terminal; acquiring, according to the terminal identity, time control information that corresponds to an application identity of an application on the terminal; and sending the time control information to the terminal, so that the terminal controls, according to the time control information, use time of the application that corresponds to the application identity.
    Type: Application
    Filed: December 20, 2013
    Publication date: April 17, 2014
    Applicant: HUAWEI DEVICE CO., LTD.
    Inventors: Cunzhi Fan, Qiang Fan, Ling Zhang, Feilong Zhang
  • IMAGING DEVICE HAVING LIGHT FIELD IMAGE SENSOR
    Publication number: 20140097252
    Abstract: A method of imaging a target object with an imaging reader. The method includes the following: (1) detecting light from the target object through a lens arrangement with an image sensor to generate light-field data; (2) generating a stream of image data including image data representing an expected in-focus image of the target object, and (3) processing the expected in-focus image of the target object to decode a barcode on the target object. The image sensor includes an array of photosensitive elements and an array of microlenses that overlays the array of photosensitive elements located at a focus plane of the microlens.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 10, 2014
    Applicant: SYMBOL TECHNOLOGIES, INC.
    Inventors: Duanfeng He, Vladimir Gurevich, David P. Goren, Nong-Qiang Fan
  • Method of enhancing lysosomal ?-galactosidase A
    Patent number: 8633221
    Abstract: A method of enhancing the activity of lysosomal ?-Galactosidase A (?-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: January 21, 2014
    Assignee: Mount Sinai School of Medicine of New York University
    Inventors: Jian-Qiang Fan, Satoshi Ishii
  • Imaging device having light field sensor
    Patent number: 8602308
    Abstract: A method of imaging a target object with an imaging reader. The method includes the following: (1) detecting light from the target object through a lens arrangement with an image sensor to generate light-field data; (2) generating a stream of image data including image data representing an expected in-focus image of the target object, and (3) processing the expected in-focus image of the target object to decode a barcode on the target object. The image sensor includes an array of photosensitive elements and an array of microlenses that overlays the array of photosensitive elements located at a focus plane of the microlens.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: December 10, 2013
    Assignee: Symbol Technologies, Inc.
    Inventors: Duanfeng He, Vladimir P. Gurevich, David P. Goren, Nong-Qiang Fan
  • IMAGING DEVICE HAVING LIGHT FIELD SENSOR
    Publication number: 20130161399
    Abstract: A method of imaging a target object with an imaging reader. The method includes the following: (1) detecting light from the target object through a lens arrangement with an image sensor to generate light-field data; (2) generating a stream of image data including image data representing an expected in-focus image of the target object, and (3) processing the expected in-focus image of the target object to decode a barcode on the target object. The image sensor includes an array of photosensitive elements and an array of microlenses that overlays the array of photosensitive elements located at a focus plane of the microlens.
    Type: Application
    Filed: December 22, 2011
    Publication date: June 27, 2013
    Applicant: SYMBOL TECHNOLOGIES, INC.
    Inventors: Duanfeng He, Vladimir Gurevich, David P. Goren, Nong-Qiang Fan
  • Method for increasing the activity of lysosomal enzymes
    Patent number: 8436018
    Abstract: Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method are imino sugars and related compounds. In particular, C8-12-alkyl derivatives of N-alkyl-deoxynojirimycin, isofagomine compounds, and calystegine compounds are effective to enhance glucocerebrosidase activity.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: May 7, 2013
    Assignee: Mount Sinai School of Medicine of New York University
    Inventors: Jian-Qiang Fan, Satoshi Ishii, Naoki Asano
  • Halogen-Free, Flame Retardant TPU Composite
    Publication number: 20130059955
    Abstract: Halogen-free TPU compositions comprise in weight percent based on the weight of the composition: A. 1 to 99% thermoplastic polyurethane (TPU), B. 1 to 50% tris(2-butoxyethyl)phosphate (TBEP), C. 1 to 70% metal hydrate, and D. 1 to 70% organic phosphate ester other than tris(2-butoxyethyl)phosphate. These compositions exhibit better smoke suppression as compared with conventional organic phosphate flame retardant TPU compositions such as those based on resorcinol bis(diphenyl phosphate) (RDP) and bisphenol-A bis(diphenyl phosphate) (BPADP) in the absence of TBEP.
    Type: Application
    Filed: June 3, 2010
    Publication date: March 7, 2013
    Inventors: Xiangyang Tai, Given Jing Chen, Yurong Cao, Li Qiang Fan
  • HALOGEN-FREE FLAME RETARDANT THERMOPLASTIC COMPOSITIONS FOR WIRE AND CABLE APPLICATIONS
    Publication number: 20120261163
    Abstract: Disclosed is a halogen-free, flame retardant thermoplastic resin composition based on polypropylene and one or more thermoplastic elastomers with an organic nitrogen- and/or phosphorus-based intumescent flame retardant comprising a piperazine component. The composition is processed easily to make a wire and cable sheath exhibiting a balance of high flame retardancy, good flexibility, high wet electrical resistance and excellent heat deformation properties, and which passes the VW-I flame retardancy test, the UL1581 heat deformation test at 150° C. and the wet electrical resistance test, and also exhibits good tensile and flexibility properties. Also disclosed is a wire and cable sheath made from the composition.
    Type: Application
    Filed: December 31, 2009
    Publication date: October 18, 2012
    Applicant: Dow Global Technologies Inc.
    Inventors: Xiang Yang Tai, Yabin Sun, Yurong Cao, Li Qiang Fan, Lin Fu, Geoffrey D. Brown, Manish Mundra
  • Thermoplastic Polymer Blends Comprising Dynamically Crosslinked Polyurethane in an Olefin Polymer Matrix
    Publication number: 20120238689
    Abstract: Compatibilized blends comprising a first phase comprising a thermoplastic olefin polymer and a second phase comprising a crosslinked, thermoplastic polyurethane are provided. The first phase is a continuous phase and the second phase can be co-5 continuous with the first phase, or dispersed as a non-continuous phase in the first phase. The blends further include a phenolic resole resin which at least partially crosslinks the thermoplastic polyurethane and acts as a compatibilizer for the olefin polymer and the thermoplastic polyurethane.
    Type: Application
    Filed: December 11, 2009
    Publication date: September 20, 2012
    Inventors: Yabin Sun, Xiang Yang Tai, Li Qiang Fan
  • METHODS FOR TREATING OBSTRUCTIVE SLEEP APNEA
    Publication number: 20120197235
    Abstract: The present invention relates to methods for treating obstructive sleep apnea (OSA), alleviating a negative OSA symptom, reducing snoring, or improving quality of life in a subject, comprising administering to the subject an effective amount of a pharmaceutical composition comprising pyridostigmine before sleep. Also provided are related medicaments as well as methods for preparing the medicaments.
    Type: Application
    Filed: January 27, 2012
    Publication date: August 2, 2012
    Inventor: Jian-Qiang FAN
  • METHOD FOR INCREASING THE ACTIVITY OF LYSOSOMAL ENZYMES
    Publication number: 20110076765
    Abstract: Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method are imino sugars and related compounds. In particular, C8-12-alkyl derivatives of N-alkyl-deoxynojirimycin, isofagomine compounds, and calystegine compounds are effective to enhance glucocerebrosidase activity.
    Type: Application
    Filed: September 24, 2010
    Publication date: March 31, 2011
    Applicant: Mount Sinai School of Medicine of New York University
    Inventors: Jian-Qiang Fan, Satoshi Ishii, Naoki Asano
  • Method for increasing the activity of acid-?-galactosidase
    Patent number: 7812033
    Abstract: Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method are imino sugars and related compounds. In particular, C8-12-alkyl derivatives of N-alkyl-deoxynojirimycin, isofagomine compounds, and calystegine compoiunds are effective to enhance glucocerebrosidase activity.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: October 12, 2010
    Assignee: Mount Sinai School of Medicine of New York University
    Inventors: Jian-Qiang Fan, Satoshi Ishii, Naoki Asano
  • HYDROXY PIPERIDINE DERIVATIVES TO TREAT GAUCHER DISEASE
    Publication number: 20100189708
    Abstract: The present invention provides novel hydroxy piperidine (HP) derivatives having (i) a positive charge at the position corresponding to the anomeric position of a pyranose ring; (ii) a short, flexible linker emanating from the corresponding position of the ring oxygen in a pyranose; and (iii) a lipophilic moiety connected to the linker and pharmaceutically acceptable salts thereof. The linker can be absent if the lipophilic moiety corresponds to a hydrocarbon chain with a linear length of 6 or more carbons. The present invention further provides a method for treating individuals having Gaucher disease by administering the novel HP derivative as “active-site specific chaperones” for the mutant glucocerebrosidase associated with the disease.
    Type: Application
    Filed: April 8, 2010
    Publication date: July 29, 2010
    Applicant: AMICUS THERAPEUTICS, INC.
    Inventors: Jian-Qiang Fan, Xiaoxiang Zhu, Kamlesh Sheth
  • Hydroxy piperidine derivatives to treat gaucher disease
    Patent number: 7741340
    Abstract: The present invention provides novel hydroxy piperidine (HP) derivatives having (i) a positive charge at the position corresponding to the anomeric position of a pyranose ring; (ii) a short, flexible linker emanating from the corresponding position of the ring oxygen in a pyranose; and (iii) a lipophilic moiety connected to the linker and pharmaceutically acceptable salts thereof. The linker can be absent if the lipophilic moiety corresponds to a hydrocarbon chain with a linear length of 6 or more carbons. The present invention further provides a method for treating individuals having Gaucher disease by administering the novel HP derivative as “active-site specific chaperones” for the mutant glucocerebrosidase associated with the disease.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: June 22, 2010
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Jian-Qiang Fan, Xiaoxiang Zhu, Kamlesh Sheth
  • Method Of Enhancing Lysosomal Alpha-Galactosidase A
    Publication number: 20100137229
    Abstract: A method of enhancing the activity of lysosomal ?-Galactosidase A (?-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.
    Type: Application
    Filed: November 23, 2009
    Publication date: June 3, 2010
    Inventors: Jian-Qiang Fan, Satoshi Ishii
  • PHARMACOLOGICAL CHAPERONES FOR TREATING OBESITY
    Publication number: 20090312345
    Abstract: The invention relates to methods of enhancing normal melanocortin-4 receptor (MC4R) activity, and to enhancing activity of an MC4R having a mutation which affects protein folding and/or processing of the MC4R. The invention provides a method of treating an individual having a condition in which increased activity of an MC4R at the cell surface would be beneficial, for example in obesity, by administering an effective amount of a pharmacological chaperone for the MC4R. The invention provides MC4R pharmacological chaperones which enhance the activity of MC4R. The invention further provides a method of screening to identify pharmacological chaperones which enhance folding of an MC4R in the endoplasmic reticulum (ER), in order to enhance the activity of the MC4R at the cell surface.
    Type: Application
    Filed: August 3, 2009
    Publication date: December 17, 2009
    Applicants: AMICUS THERAPEUTICS, INC., UNIVERSITE DE MONTREAL
    Inventors: Jian-Qiang Fan, Ken Valenzano, Gary Lee, Michel Bouvier
  • Method of enhancing lysosomal ?-galactosidase A
    Patent number: 7622485
    Abstract: A method of enhancing the activity of lysosomal ?-Galactosidase A (?-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.
    Type: Grant
    Filed: June 14, 2004
    Date of Patent: November 24, 2009
    Assignee: Mount Sinai School of Medicine of New York University
    Inventors: Jian-Qiang Fan, Satoshi Ishii
  • HOT FUNCTION SETTING METHOD AND SYSTEM
    Publication number: 20090160814
    Abstract: A method for setting a hot function for a user on an electronic device having a touch screen, hot function modules for providing hot functions, and a database storing recognizable traits, the recognizable traits being corresponding to the hot function modules. The function setting method includes the steps of: (i) recognizing traits input by the user through the touch screen; (ii) matching the input traits with at least one of the recognizable traits in the database; and (iii) activating at least one of the hot function modules to set at least one hot function, wherein the least one of the hot function modules corresponds to the least one of the recognizable traits.
    Type: Application
    Filed: December 19, 2008
    Publication date: June 25, 2009
    Inventors: Yuan LI, Qiang Fan