Abstract: Embodiments disclosed herein include a diagnostic substrate. In an embodiment, the diagnostic substrate comprises a substrate, a circuit board on the substrate, and a spectrometer coupled to the circuit board. In an embodiment, the diagnostic substrate further comprises a processor on the circuit board and communicatively coupled to the spectrometer.

Abstract: The present invention relates methods for treating thyroid cancer, renal cell carcinoma or hepatocellar carcinoma comprising orally administering to a patient in need of such therapy a therapeutic amount of cabozantinib lauryl sulfate salt, preferably in a capsule form. The method allows the administration of the therapeutic amount of cabozantinib lauryl sulfate salt in a fed state or a fasted state and the administration does not exhibit a food effect.

Abstract: The present invention relates methods for treating thyroid cancer, renal cell carcinoma or hepatocellar carcinoma comprising orally administering to a patient in need of such therapy a therapeutic amount of cabozantinib lauryl sulfate salt, preferably in a capsule form. The method allows the administration of the therapeutic amount of cabozantinib lauryl sulfate salt in a fed state or a fasted state and the administration does not exhibit a food effect.

Abstract: The present invention disclosed a 1,4-diheterocyclic substituted aromatic ring or aromatic heterocyclic compound represented by formula (I). The compound can effectively inhibit the generation of 20-HETE, and has high activity, high selectivity and good pharmacokinetic characteristics. By means of the inhibition on the generation of 20-HETE, the compound can be used for treating various diseases related to 20-HETE, and thus has a great application value.

Abstract: A portable electronic device, and an image-capturing device and an assembly method thereof are provided. The image-capturing device includes a carrier substrate, an image sensing chip, a filter element and a lens assembly. The carrier substrate has a through opening and a recessed space. The image sensing chip is disposed on the bottom side of the carrier substrate. The filter element is disposed in the recessed space of the carrier substrate, so that all or a part of the filter element is accommodated in the through opening. When at least one microparticle with a maximum particle size between 5 ?m and 25 ?m is located on the filter element, a shortest distance between the filter element and the image sensing chip is between 30 ?m and 200 ?m, so that the image sensing chip cannot capture a light spot generated due to blocking of the microparticle.

Abstract: A passive radiator module includes a cavity and two passive radiators, and the two passive radiators are disposed on an upper surface and a lower surface of the cavity respectively. Each of the two passive radiators includes a hang edge, a surrounding part and a diaphragm, the surrounding part surrounds the diaphragm, and the surrounding part is positioned between the hang edge and the diaphragm. Each of the upper surface and the lower surface includes a hollow part, the hang edge of any one of the two passive radiators is connected to a corresponding one of the upper surface and the lower surface, and the diaphragm of said any one of the two passive radiators is positioned in the hollow part of the corresponding one of the upper surface and the lower surface.

Abstract: The present subject matter relates to devices and techniques for preparing a sample. The disclosed device can include a mixer, a reaction channel, and a micro sprayer. The mixer can be configured to mix at least two components and perform a splitting and recombination (SAR) mixing. The micro sprayer can be configured to generate a droplet of the sample. The mixer and the micro sprayer can be coupled through the reaction channel. The reaction channel can be a microcapillary tubing or a yin-yang reaction channel.

Abstract: A SpyCatcher peptide-modified carrier, a protein immobilizing carrier, and a protein immobilizing method. The method comprises: linking a SpyCatcher peptide to a carrier so as to obtain a SpyCatcher peptide-modified carrier; and then based on a SpyCatcher-SpyTag reaction, immobilizing a target protein containing SpyTag to the SpyCatcher-modified carrier. A protein immobilization process in which the method is used is fast, a condition is mild, no extra chemical reagent is needed, the immobilization efficiency and an activity recovery rate are high, and the homogeneity is good.

Abstract: A microdevice for monitoring a target analyte is provided. The microdevice can include a field effect transistor comprising a substrate, a gate electrode, and a microfluidic channel including graphene. The microfluidic channel can be formed between drain electrodes and source electrodes on the substrate. The microdevice can also include at least one aptamer functionalized on a surface of the graphene. The at least one aptamer can be adapted for binding to the target analyte. Binding of the target analyte to the at least one aptamer can alter the conductance of the graphene.

Abstract: A silicone cup is provided. The silicone cup includes a body made of a silicone. The silicone cup also includes a plurality of concave measurement windows provided on an exterior surface of the body.

Abstract: A method for wafer image equalization includes obtaining a wafer image, converting the wafer image into bitmap data, generating a grayscale distribution of RGB pixels according to the bitmap data, generating a grayscale cumulative probability distribution of the RGB pixels according to the grayscale distribution, generating a mapping function according to the grayscale cumulative probability distribution of the RGB pixels, converting the grayscale distribution of the RGB pixels by the mapping function into an equalized grayscale distribution of the RGB pixels, and generating an equalized wafer image according to the equalized grayscale distribution of the RGB pixels.

Abstract: The present disclosure pertains to the technical field of electric motors, and discloses an electric motor and an electric toy. The electric motor includes a stator assembly, a rotor assembly, a front end cover assembly, a rear end cover assembly, a three-phase power line, and a data transmission line. The rotor assembly is sleeved on the stator assembly. The rotor assembly includes a magnetic ring, a magnetic knitting frame, an iron core, several tile-shaped magnets, a rotating shaft, and a rotor end plate. A positioning slot is arranged between adjacent tile-shaped magnets. The magnetic knitting frame is provided with a positioning boss that is inserted into the structure of the positioning slot. The electric motor allows the accurate positioning and assembling of the rotor assembly, so that the magnetic poles of the magnetic ring correspond to the magnetic poles of the tile-shaped magnet.

Abstract: An electric motor and an electric toy, wherein the electric motor includes a stator assembly, a rotor assembly, a front end cover assembly, a rear end cover assembly, a three-phase power line, and a data transmission line. The rotor assembly is sleeved on the stator assembly. The rotor assembly includes a magnetic ring, a magnetic knitting frame, an iron core, several tile-shaped magnets, a rotating shaft, and a rotor end plate. A positioning slot is arranged between adjacent tile-shaped magnets. The magnetic knitting frame is provided with a positioning boss that is inserted into the structure of the positioning slot. The electric motor allows the accurate positioning and assembling of the rotor assembly, so that the magnetic poles of the magnetic ring correspond to the magnetic poles of the tile-shaped magnet.

Abstract: A portable electronic device, and an image-capturing device and an assembly method thereof are provided. The image-capturing device includes a carrier substrate, an image sensing chip, a filter element and a lens assembly. The carrier substrate has a through opening and a recessed space. The image sensing chip is disposed on the bottom side of the carrier substrate. The filter element is disposed in the recessed space of the carrier substrate, so that all or a part of the filter element is accommodated in the through opening. When at least one microparticle with a maximum particle size between 5 ?m and 25 ?m is located on the filter element, a shortest distance between the filter element and the image sensing chip is between 30 ?m and 200 ?m, so that the image sensing chip cannot capture a light spot generated due to blocking of the microparticle.