Abstract: A crosstalk-suppressing image sensor includes a semiconductor substrate, an opaque layer, and a spectral filter. The semiconductor substrate includes a photodiode therein and is located beneath a light-exposure region of a back surface of the semiconductor substrate. The opaque layer is on the back surface, partially covers the light-exposure region, and has an opaque-layer thickness perpendicular to an image-plane direction parallel to the back surface. The spectral filter is adjacent to the opaque layer in the image-plane direction, and partially covers the light-exposure region.

Abstract: The invention relates to a method for preparing nicotinamide mononucleotide by using nicotinamide as a raw material, which comprises: in acetonitrile, dichloromethane, 1,2-dichloroethane or liquid sulfur dioxide as a solvent, allowing nicotinamide and tetraacetyl ribose to react as catalyzed by trimethylsilyl trifluoromethanesulfonate or tin tetrachloride, adjusting a pH value thereof to 3-5, adding a sodium methoxide solution thereto to react at ?15° C. to 5° C., adjusting a pH value thereof to 3-5, and subjecting the reaction mixture to microfiltration and nanofiltration using a membrane concentrator, thereby obtain a nicotinamide ribose solution; allowing the nicotinamide ribose solution to react as catalyzed by nicotinamide ribokinase in the presence of Mg ions, ATP and a buffer, thereby obtaining nicotinamide mononucleotide.

Abstract: A conductive terminal to be mated with a mating terminal includes: a base; and a mating end at a front of the base for mating with the mating terminal, the mating end including a first mating portion for contacting with the mating terminal and a second mating portion arranged in front of the first mating portion for contacting with the mating terminal, wherein the first mating portion includes a first protrusion, the second mating portion includes a second protrusion, the first protrusion and the second protrusion protrude toward same side of the conductive terminal, the contacting direction and manner between the first protrusion and the mating terminal are different from the contacting direction and manner between the second protrusion and the mating terminal.

Abstract: A fixed cutting structure-composite cone drill bit includes a drill bit body, a fixed cutting structure, and at least one cone. The cone and the fixed cutting structure are disposed on the drill bit body. The cone is rotatably connected to the drill bit body by means of a bearing structure. The distance from the outermost tooth or back cone of the at least one cone to the front side surface of the fixed cutting structure La??R/3, and the distance from the outermost tooth or back cone of the at least one cone to the rear side surface of the fixed cutting structure Lb??R/3. In the composite drill bit, the distance from the cone to the front/rear side surface of the fixed cutting structure is short, the gap between the cone and the fixed cutting structure is small, transition between cutting structure is smooth.

Abstract: A Quantum Digital Signature (QDS)-based mail system and a transceiving method are provided. The system is a three-layer structure formed by a physical layer, a key layer, and an application layer. The physical layer is a key generation terminal and is used to generate a key string for signature in real time; the key layer is used to store the key string generated by the physical layer and provide a required key to the upper layer, namely, the application layer when required; and the application layer is a transceiving software part in the mail system, and is used to extract keys generated by the physical layer from the key layer so as to encrypt information to be sent. The mail transceiving method comprises: a quantum key distribution (QKD) phase, a mail signature phase, and a signature verification phase.

Abstract: An electrical connector includes: an insulative housing having a slot; plural contacts secured in the insulative housing and exposed to the slot; and a metallic shell mounted to the insulative housing and having a top plate, a bottom plate, and a connecting part connected to the top plate at an upper end thereof and connected to the bottom plate at a lower end thereof, wherein the top plate has a pair of actuating arms and the connecting part has a pair of locking arms, and the top plate is movable about the upper end of the connecting part to actuate the pair of locking arms by the pair of actuating arms.

Abstract: An information handling system includes a processor, a system baseboard management controller (BMC), and a field-programmable gate array (FPGA) add-in card. The FPGA add-in card includes an FPGA and a card BMC. The FPGA is programmed with a plurality of accelerated function units (AFUs) to perform processing tasks for the processor. The card BMC receives a first indication from the system BMC, the first indication to halt a first processing task associated with a first AFU, halts the first processing task in response to the first indication, receives a second AFU from the system BMC, and reprograms the FPGA with the second AFU.

Abstract: The present invention relates to a pharmaceutical combination which comprises (a) a phosphatidylinositol 3-kinase inhibitor or pharmaceutically acceptable salt thereof, and (b) at least one c-Met receptor tyrosine kinase inhibitor or pharmaceutically acceptable salt thereof, for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly a c-Met dependent proliferative disease; a pharmaceutical composition comprising such combination; a method of treating a subject having a proliferative disease comprising administration of said combination to a subject in need thereof; use of such combination for the treatment of proliferative disease; and a commercial package comprising such combination.

Abstract: The present invention relates to the combination of the HDM2-p53 interaction inhibitor drug (S)-5-(5-Chloro-1-methyl-2-oxo-1,2-dihydro-pyridin-3-yl)-6-(4-chloro-phenyl)-2-(2,4-dimethoxy-pyrimidin-5-yl)-1-isopropyl-5,6-dihydro-1H-pyrrolo[3,4-d]imidazol-4-one [HDM201] and an anti-TIM-3 antibody molecule as TIM-3 inhibitor. The present invention further relates to the use of said combination in the treatment of cancer, in particular hematological tumors. The present invention further relates to dose and dosing regimen related to this combination cancer treatment.

Abstract: A pixel circuit includes a trench etched into a front side surface of a semiconductor substrate. The trench includes a bottom surface etched along a <100> crystalline plane and a tilted side surface etched along a <111> crystalline plane that extends between the bottom surface and the front side surface. A floating diffusion is disposed in the semiconductor substrate beneath the bottom surface of the trench. A photodiode is disposed in the semiconductor substrate beneath the tilted side surface of the trench and is separated from the floating diffusion. The photodiode is configured to photogenerate image charge in response to incident light. A tilted transfer gate is disposed over at least a portion of the bottom surface and at least a portion of the tilted side surface of the trench. The tilted transfer gate is configured to transfer the image charge from the photodiode to the floating diffusion.

Abstract: An electrical connector includes: a housing; and plurality terminal groups held on the housing, each terminal group including a pair of signal terminals, a first shielding sheet for shielding the pair of signal terminals on at least one side, and a second shielding sheet for shielding the signal terminals on at least another side; wherein the first shielding sheet and the second shielding sheet of each terminal group are electrically connected, and the first shielding sheet of one of the terminal groups is electrically connected to the second shielding sheet of an adjacent terminal group.

Abstract: An information handling system includes a first device having a first data communication interface connected to a first socket area of a socket. A second device includes a second data communication interface connected to a second socket area of the socket. A host processor includes a third data communication interface connected to a third socket area of the socket. When an interposer is installed into the socket in a first orientation, the interposer connects the first data communication interface to the third data communication interface. When the interposer is installed into the socket in a second orientation, the interposer connects the first data communication interface to the second data communication interface.

Abstract: The present invention relates to the field of quantum communication, especially a quantum key distribution device that can be configured with multiple protocols. It uses the simplified Faraday-Michelson interference ring in combination with the intensity modulator to perform timestamp encoding in a chopping manner. The phase modulation is completed with a Sagnac ring device composed of a single-polarization phase modulator, a polarization beam splitter and a Faraday rotator, so as to achieve the purpose of composite encoding and decoding, thus realizing a quantum key distribution device which can be configured with multiple protocols and multiple decoy state schemes. This device can be compatible with multiple protocols including BB84 protocol, the reference frame-independent protocol, the six-state protocol and SARG protocol and is characterized with polarization-independent phase modulation and low system complexity.

Abstract: A pharmaceutical combination comprising an ALK inhibitor, in free form or a pharmaceutically acceptable salt thereof, and a SHP2 inhibitor, in free form or a pharmaceutically acceptable salt thereof, and optionally a pharmaceutically acceptable carrier, for simultaneous or sequential administration; the uses of such combination in the treatment of proliferative diseases; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.

Abstract: Provided is a mobile water quality monitoring platform for a fishpond, belonging to the technical field of water quality monitoring devices. The mobile water quality monitoring platform for a fishpond includes a floating body, a first rotating shaft and a second rotating shaft are disposed on the floating body, the first rotating shaft is rotatably disposed on the floating body through two first support plates, two second support plates are vertically disposed on the floating body, an elongated chute hole is horizontally disposed on two second support plates respectively, both ends of the second rotating shaft are inserted into two chute holes respectively, the first rotating shaft and the second rotating shaft are connected through a connecting rod mechanism, a driving mechanism that enables the first rotating shaft and the second rotating shaft to rotate simultaneously is disposed on the connecting rod mechanism.

Abstract: A method and a system for recommending a target garment matching an inputted garment. The method includes: extracting attributes from text description and image of the inputted garment to obtain extracted attributes; querying a knowledge graph using the extracted attributes to obtain matched attributes; retrieving candidate products from a garment pool using the matched attributes; extracting features from the inputted garment and the candidate products; determining the target garment from the candidate products based on grading scores between the features of the inputted garment and the features of the candidate products; and recommending the target garment. The knowledge graph includes nodes corresponding to type of clothes, category of clothes, attribute keys, values of attribute keys, context keys, values of context keys, combination of the values of the attribute keys and the type of clothes, and combination of the value of the attribute keys and the category of clothes.

Abstract: An active feedback control method for a quantum communication system based on machine learning is disclosed. In the transmission process of a quantum key distribution system, the present invention uses a pre-trained double-layer LSTM network to predict, according to a real-time ambient temperature, humidity and laser light intensity fluctuation, as well as voltage changes in the past moment, a zero-phase voltage value of a phase modulator at a receiving end at the next moment, and updates the network at a fixed time interval, so that the LSTM network can accurately predict for a long time, ensuring that the quantum key distribution system operates stably and efficiently for a long time. The present invention greatly improves the transmission efficiency of the quantum key distribution system by method of active prediction and feedback control.

Abstract: Circuit integrated with voice wake-up function, television and voice control method. The circuit integrated with voice wake-up function comprises television mainboard and far-field voice module. The far-field voice module comprises: microphone unit for collecting voice simulation signal; analog-digital conversion unit for converting voice simulation signal to digital signal; main control unit for processing converted digital signal and outputting same to television mainboard; and voice wake-up unit for processing voice simulation signal and outputting wake-up signal to television mainboard. Microphone unit is connected to analog-digital conversion unit and voice recognition unit, respectively; analog-digital conversion unit is connected to main control unit and television mainboard, respectively; and television mainboard is connected to main control unit and voice wake-up unit, respectively.

Abstract: In accordance with one embodiment, a fan controller operates in a standard mode when main power is provided to the power supply unit in which speed of the fan is controlled in response to a primary pulse width modulation (PWM) signal from a power controller. A loss of the main power to the power supply unit may be detected at a logic circuit, which provides a secondary PWM signal to the fan controller in response to the loss of the main power. In certain embodiments, the fan controller is operated in a power loss mode in response to the secondary PWM signal to direct the speed of the fan to a low-power consumption target speed.

Abstract: The present invention provides a puncture support, including a support body and a soft support coating covering the outside of the support body, wherein a needle insertion channel is provided inside the support body. During use, the puncture support is fixedly connected to an ultrasonic probe by using the hard support body, and the soft support coating attached to the support body is in contact with a human body. Because the support coating is made of a soft material, people feel soft with reduced foreign body sensation when in contact with the support coating. In addition, the support body is made of a hard material, so that the puncture support can be firmly installed, ensuring safety. Therefore, the puncture support can be firmly and reliably installed like an existing puncture support, and also increases the comfort level of the product by taking user feelings into account.