Abstract: The present invention provides an anti-ovarian cancer bispecific antibody. Said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti-ovarian cancer antibody, or its Fab fragment, single complementarity determining region (CDR) antibody or single chain Fv (scFv) and the other is anti-CD3 antibody, or its Fab fragment, single CDR antibody or scFv. The present invention also provides DNA sequences encoding said antibody, an expression vector containing said DNA sequence, and a host cell containing said expression vector.

Abstract: A method to improve TCP throughput by separating TCP acknowledgment flow from TCP normal data flow in a wireless communications environment. This method creates dedicated signaling air interface link and signaling A10 link for TCP acknowledgment flow and assigns a higher priority value to TOS field of IP packets encapsulating TCP acknowledgments than those encapsulating TCP normal data.

Abstract: A method for controlling communications traffic on an inter-access-network link includes receiving a request for transmission of a traffic flow and determining a priority queue associated with the traffic flow. If the priority queue corresponds to the one of a first plurality of priority levels, the method further includes determining whether one or more predetermined criteria for the traffic flow are satisfied. If yes, the method additionally admitting the traffic flow, storing information associated with the traffic flow in the queue, and transmitting information associated with the traffic flow from the queue based on at least a strict priority process. If the queue corresponds to the one of a second plurality of priority levels, the method further admitting the traffic flow, storing information associated with the traffic flow in the queue, and transmitting information associated with the traffic flow from the queue based on at least an arbitrated priority process.

Abstract: A modular picket fence including a pair of vertical posts positioned at suitable distance and adapted to be secured to a suitable support surface. A pair of horizontal upper and lower rails extend between and secured to the vertical posts. The upper rail has a plurality of apertures which are aligned with a plurality of apertures on the lower rail. The apertures can be of any given shape including square, narrow rectangular, wide rectangular, oval, round, narrow polygonal and wide polygonal. A plurality of vertical pickets having a cross-sectional shape corresponding to the shape of the apertures in the horizontal rails are respectively inserted through into aligned apertures of the upper and lower rails. The end portion of each vertical picket has two transverse apertures.

Abstract: Embodiments include floral picks for use with decorative foliage. One embodiment includes a floral pick including a body comprising a first body member and a second body member. The second member has a recess configured to receive the first body member. At least one wing includes a central portion positioned between the first body member and the second body member. A shaft is coupled to the body.

Abstract: A tool chest assembly includes a lower cabinet and an upper cabinet. The upper cabinet is configured to fit inside the lower cabinet during shipping or storage to save space. The tool chest assembly is configured for easy set-up and handling.

Abstract: The present invention provides an anti-ovarian cancer bispecific antibody. Said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti-ovarian cancer antibody, or its Fab fragment, single complementarity determining region (CDR) antibody or single chain Fv (scFv) and the other is anti-CD3 antibody, or its Fab fragment, single CDR antibody or scFv. The present invention also provides DNA sequences encoding said antibody, an expression vector containing said DNA sequence, and a host cell containing said expression vector.

Abstract: The present invention according to certain embodiments is directed to a method, device and apparatus for repairing a plurality of memory locations. The present invention includes providing a plurality of memory locations, providing a plurality of fuses coupled to the memory locations and loading fuse data into a data register from a plurality of read-only memory (ROM) devices thereby creating loaded fuse data. The present invention also provides loading a programming sequence of the memory device, wherein the programming sequence includes a plurality of memory addresses, and reading the loaded fuse data from the fuse register to a plurality of memory locations corresponding to the plurality of memory addresses.

Abstract: A highly purified and specific glycosaminoglycan degrading enzyme, chondroitinase AC, and to a lesser extent, chondroitinase B, can be used in the treatment of metastatic cancers and in other disorders characterized by angiogenesis. The enzymatic removal of chondroitin sulfates A and C, and to a lesser extent, chondroitin sulfate B, from cell surfaces directly decreases the ability of tumor cells to invade blood vessels and thus prevents the formation of metastatic, or secondary tumors; inhibits tumor cell growth; and decreases angiogenesis by inhibiting both endothelial cell proliferation and capillary formation. Decreasing the formation of new blood vessels into the tumor in turn decreases the potential for tumor growth, and further decreases the ability of tumor cells to invade the bloodstream. These effects are opposite to the prometastatic effects of tumor-secreted heparanase.

Abstract: The present invention provides an anti-ovarian cancer bispecific antibody. Said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti-ovarian cancer antibody, or its Fab fragment, single complementarity determining region (CDR) antibody or single chain Fv (scFv) and the other is anti-CD3 antibody, or its Fab fragment, single CDR antibody or scFv. The present invention also provides DNA sequences encoding said antibody, an expression vector containing said DNA sequence, and a host cell containing said expression vector.

Abstract: Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer.

Abstract: The invention provides a cyclic single-chain trispecific antibody against human tumor. It comprises three parts. The first part is an anti-tumor Fab antibody, an anti-tumor single-domain antibody or an scFv. The second part is a reshaped Fab antibody against human CD3, a reshaped single-domain antibody against human CD3 or a reshaped scFv against human CD3. The third part is a reshaped Fab antibody against human CD28, a reshaped single-domain antibody against human CD28 or a reshaped scFv against human CD28. The present invention also offers the DNA sequence coding for this trispecific antibody, expression vectors containing this DNA sequence and host cells (E. coli) containing the vectors.

Abstract: A highly purified and specific glycosaminoglycan degrading enzyme, chondroitinase AC, and to a lesser extent, chondroitinase B, can be used in the treatment of metastatic cancers and in other disorders characterized by angiogenesis. The enzymatic removal of chondroitin sulfates A and C, and to a lesser extent, chondroitin sulfate B, from cell surfaces directly decreases the ability of tumor cells to invade blood vessels and thus prevents the formation of metastatic, or secondary tumors; inhibits tumor cell growth; and decreases angiogenesis by inhibiting both endothelial cell proliferation and capillary formation. Decreasing the formation of new blood vessels into the tumor in turn decreases the potential for tumor growth, and further decreases the ability of tumor cells to invade the bloodstream. These effects are opposite to the pro-metastatic effects of tumor-secreted heparanase.

Abstract: A slipper includes a sole body having a plurality of apertures defined through the sole body and a plurality of protrusions extend from a top surface of the sole body. A skirt flange extends from a periphery of the bottom of the sole body and a plurality of notches are defined in a lower edge of the skirt flange. A plurality of cylindrical rods extend from the bottom of the sole body and share a common axis with the protrusions on the top surface of the sole body.

Abstract: A sole for footwear includes a sole body having a plurality of protrusions extending from a top surface of the sole body so as to support the wearer's foot. A plurality of apertures are defined through said sole body and located between said protrusions.