Patents by Inventor Qing Shi

Qing Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10723851
    Abstract: A film comprising, consisting of, or consisting essentially of: a) a polyolefin component; b) an additive comprising i) a first polyethylene oxide/polyethylene copolymer having a HLB value in the range of from 1 to 7 and a structure selected from the group consisting of CH3CH2(CH2CH2)aCH2CH2(OCH2CH2)bOH and CH3CH2(CH2CH2)aCO(OCH2CH2)bOH wherein a is from 9 to 25 and b is from 1 to 10; and ii) a second polyethylene oxide/polyethylene copolymer having a HLB value in the range of from 7 to 18 and a structure selected from the group consisting of CH3CH2(CH2CH2)aCH2CH2(OCH2CH2)bOH and CH3CH2(CH2CH2)aCO(OCH2CH2)bOH wherein a is from 9 to 25 and b is from 1 to 10, is disclosed. The film is used in greenhouse applications.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: July 28, 2020
    Assignee: Dow Global Technologies LLC
    Inventors: Qing Shi, Hongliang Zhang, Hongyu Chen, Hong Zheng, Yong Chen
  • Publication number: 20200181832
    Abstract: A colorant catcher material includes a) a substrate and b) a colorant-catching additive. The colorant-catching additive is selected from the group consisting of polyvinylamines in form of homopolymers, copolymers and/or partial salts thereof, polyethylenimines in form of homopolymers, copolymers and/or partial salts thereof, and mixture thereof. The colorant-catching additive is fixed on the substrate by c) a fixing agent selected from the group consisting of dialdehydes with the carbon number of from 2 to 8. Also disclosed is a method for preparing the colorant catcher material and use of the same for catching colorants or removing dirt in an aqueous medium, particularly a laundry washing solution.
    Type: Application
    Filed: November 2, 2017
    Publication date: June 11, 2020
    Inventors: Si Jun ZHU, Laszlo SZARVAS, Yuan Zhuo LING, Qing SHI
  • Publication number: 20200163976
    Abstract: As disclosed herein, novel compositions including steroid hormones, such as trimegestone (TMG) and progesterone (P4), provide treatments for term and preterm labor with significant effects on the delay of delivery. Delay and block of delivery occurs when both P4 and TMG are administered late in gestation in pregnant rat and guinea pig animal models. TMG exhibits remarkable drug efficacy, achieving the same inhibition as P4, but at much lower doses. These hereto unknown effects of TMG on the processes of cervical ripening and uterine contraction provide a novel approach for extending pregnancy term, including reducing a likelihood of preterm and/or term labor, along with improved methods of administration. Other diseases and/or conditions may be treated with TMG, such as dysmenorrhea or luteal insufficiency for sustaining pregnancy.
    Type: Application
    Filed: January 30, 2020
    Publication date: May 28, 2020
    Inventors: Robert E. Garfield, Shao-Qing Shi, Leili Shi
  • Publication number: 20200123154
    Abstract: The present invention provides a compound of Formula (I), wherein X is H or C1-C3 alkyl optionally substituted with hydroxyl; Y is H, hydroxy, or methyl; R is ethyl, n-propyl, cyclopropyl, or Formula (II); and A is methyl, cyclopropyl or trifluoromethyl; or a pharmaceutically acceptable salt thereof; with the proviso that when X and Y are both H and R is n-propyl, then A is other than methyl; for use as a human PDE1 inhibitor.
    Type: Application
    Filed: July 26, 2018
    Publication date: April 23, 2020
    Applicant: Eli Lilly and Company
    Inventors: Michael James Genin, William Glen Holloway, Richard Duane Johnston, John Richard Morphy, Qing Shi
  • Patent number: 10603877
    Abstract: A multi-layer film comprising: a) a first layer comprising i) a polyolefin component; and ii) a polyethylene oxide/polyethylene copolymer having a Hydrophile-Lipophile Balance value in the range of from 2 to 6; b) a second layer comprising i) a polyolefin component; ii) from 1 to 5 weight percent of an additive selected from the group consisting of sorbitan esters, polyoxyethylene esters, glycerol esters, polyglycerol esters, fluorine-based compounds and combinations thereof, wherein the additive has a Hydrophile-Lipophile Balance value in the range of from 7 to 18; and iii) an inorganic filler; wherein the second layer is adjacent to the first layer and c) a skin layer comprising a polyolefin component, is disclosed. The multi-layer film is used in greenhouse applications.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: March 31, 2020
    Assignee: Dow Global Technologies LLC
    Inventors: Qing Shi, Hongyu Chen, Daojin Hang, Libo Du, Andong Liu, Yong Chen
  • Patent number: 10561073
    Abstract: Embodiments of films, for example, infrared absorbing, heat retaining films, comprise at least one polymer selected from: a low density polyethylene (LDPE) having a density range of 0.900 g/cc to 0.930 g/cc and a melt index (I2) of 0.3 g/10 min to 2.0 g/10 min as measured in accordance with ASTM D1238; a linear low density polyethylene (LLDPE) having a density range of 0.900 g/cc to 0.930 g/cc and a melt index I2 of 0.3 g/10 min to 2.0 g/10 min; and a ethylene vinyl acetate copolymer having a vinyl acetate content ranging from 3 wt. % to 27 wt. % and a melt index I2 of 0.2 g/10 min to 10 g/10 min. The films also comprise a hybrid filler comprising (i) a layered double hydroxide, and (ii) an inorganic powder complex having a particle size distribution defined by a median diameter (D50) of 1.5 to 20 ?m.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: February 18, 2020
    Assignee: Dow Global Technologies LLC
    Inventors: Libo Du, Hongyu Chen, Qing Shi, Yong Chen, Hong Liang Zhang, Hong Zheng, QiQi Tang
  • Patent number: 10555955
    Abstract: As disclosed herein, novel compositions including steroid hormones, such as trimegestone (TMG) and progesterone (P4), provide treatments for term and preterm labor with significant effects on the delay of delivery. Delay and block of delivery occurs when both P4 and TMG are administered late in gestation in pregnant rat and guinea pig animal models. TMG exhibits remarkable drug efficacy, achieving the same inhibition as P4, but at much lower doses. These hereto unknown effects of TMG on the processes of cervical ripening and uterine contraction provide a novel approach for extending pregnancy term, including reducing a likelihood of preterm and/or term labor, along with improved methods of administration. Other diseases and/or conditions may be treated with TMG, such as dysmenorrhea or luteal insufficiency for sustaining pregnancy.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: February 11, 2020
    Assignee: Dignity Health
    Inventors: Robert E. Garfield, Shao-Qing Shi, Leili Shi
  • Publication number: 20200034135
    Abstract: Analyzing software change impact is provided. Feedback is received regarding a predicted impact of a software change to a set of components of a service. It is determined whether the predicted impact of the software change is correct based on the feedback. In response to determining that the predicted impact of the software change is correct based on the feedback, the software change is applied to the set of components of the service increasing performance of the service and a server computer hosting the service.
    Type: Application
    Filed: July 30, 2018
    Publication date: January 30, 2020
    Inventors: Hui Qing Shi, Yi Bin Wang, Yuan Yuan, Ya Pei Zhou, Wei Wang
  • Publication number: 20190382416
    Abstract: Disclosed are compounds of Formula (I) wherein: the two dotted lines represent either two single or two double bonds; Q is: R1 is F, Cl, —CN, or —CH3; R2 is Cl or —CH3; R3 is —C(CH3)2OH or —CH2CH2OH; Ra is H or —CH3; each Rb is independently F, Cl, —CH3, and/or —OCH3; and n is zero, 1, or 2. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
    Type: Application
    Filed: August 22, 2019
    Publication date: December 19, 2019
    Inventors: Douglas G. BATT, Myra Beaudoin Bertrand, George V. De Lucca, Michael A. Galella, Soo Sung Ko, Charles M. Langevine, Qingjie Liu, Qing Shi, Anurag S. Srivastava, Joseph A. Tino, Scott Hunter Watterson
  • Patent number: 10449183
    Abstract: The invention relates to methods and pharmaceutical compositions for inhibiting or preventing preterm birth, inhibiting or delaying cervical ripening, inhibiting myometrial contractility and treating or inhibiting uterine contractility disorders. The methods comprise administering an effective amount of a composition comprising steroid hormones such as soluble progesterone.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: October 22, 2019
    Assignee: Dignity Health
    Inventors: Robert Garfield, Shao-Qing Shi, Leili Shi
  • Publication number: 20190309378
    Abstract: The present invention relates to a process for producing leather in which methanesulfonic acid (MSA) is used in the pickling step at a high pH value, and the use of MSA is to improve the quality of the final leather product as well as to improve the environmental impact of the waste liquor.
    Type: Application
    Filed: June 12, 2017
    Publication date: October 10, 2019
    Applicant: BASF SE
    Inventors: Qing SHI, Laszlo SZARVAS, Biyu PENG, Chunxiao ZHANG
  • Patent number: 10435415
    Abstract: Disclosed are compounds of Formula (I) wherein: the two dotted lines represent either two single or two double bonds; Q is: R1 is F, Cl, —CN, or —CH3; R2 is Cl or —CH3; R3 is —C(CH3)2OH or —CH2CH2OH; Ra is H or —CH3; each Rb is independently F, Cl, —CH3, and/or —OCH3; and n is zero, 1, or 2. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: October 8, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Douglas G. Batt, Myra Beaudoin Bertrand, George V. De Lucca, Michael A. Galella, Soo Sung Ko, Charles M. Langevine, Qingjie Liu, Qing Shi, Anurag S. Srivastava, Joseph A. Tino, Scott Hunter Watterson
  • Publication number: 20190299925
    Abstract: A child transportation system is disclosed. The system includes a seating component and various other modules. The system can check whether a seating component is located in a vehicle, whether the seating component is a proper component given the weight and height of the child in the seat, that the seating component is properly secured in the vehicle, and that the system is operating correctly. The system can monitor various conditions of the seat and the environment, and can provide alarms to users when cheks are not completed or dangerous environmental conditions are present, or when a child is left behind in a vehicle.
    Type: Application
    Filed: March 12, 2019
    Publication date: October 3, 2019
    Inventors: Qing Shi, Nicolas Gonzalez Garrido, Vojislav Mokric, Srdjan Jovanovic
  • Publication number: 20190166208
    Abstract: Cognitively detecting cloud services and their associated status of a Virtual Machine and/or Container in a cloud platform to predict availability of cloud services preferably including the status of the services, a service object health map, and a service health status. The outputs are preferably sent to a user for feedback, which is sent back to the cognitive service.
    Type: Application
    Filed: November 28, 2017
    Publication date: May 30, 2019
    Inventors: Hui Qing Shi, Wei Wang, Yi Bin Wang, Yuan Yuan, Ya Pei Zhou
  • Publication number: 20190147354
    Abstract: A method for event identification including receiving event information pertaining to events occurring with respect to a computing environment, each event having a measurement metric; evaluating by a probability function the measurement metric for each event to determine when the measurement metric is above a predetermined probability threshold or below a probability threshold wherein above a probability threshold or below a probability threshold is classified as alarm data; processing the alarm data through a decision tree to determine based on historical data when the alarm data is significant or when the alarm data is not significant and to reduce the number of alarm data to a predetermined number of significant alarm data; and displaying the predetermined number of significant alarm data to a user.
    Type: Application
    Filed: November 13, 2017
    Publication date: May 16, 2019
    Inventors: Xue Feng Gao, Hui Qing Shi, James C. Thorburn, Yu Fen Yuan, Qing Feng Zhang
  • Publication number: 20190097942
    Abstract: An approach is provided for orchestrating computing resources between different computing environments. Data from first and second computing environments is monitored. The data specifies utilization of infrastructure, middleware, software testing tools, integrated development environments (IDEs), relationships among nodes, utilization of the nodes, and user behavior in the first and second computing environments. Based on the utilization of the infrastructure, middleware, tools, IDEs, node relationships and utilization, and user behavior, a pattern decision tree is updated, and unbalanced workloads are identified. Based on a comparison of the unbalanced workloads to patterns in the updated pattern decision tree, an orchestration topology is generated that specifies a new placement of the computing resources in the first and second computing environments.
    Type: Application
    Filed: November 26, 2018
    Publication date: March 28, 2019
    Inventors: Xue Feng Gao, Hui Qing Shi, Qing Feng Zhang, Zhi Feng Zhao
  • Patent number: 10214537
    Abstract: Disclosed are compounds of Formula (I) or a salt thereof; wherein: X is N or CH; Q1 is: (i) Cl, Br, I, —CN, —CH3, or —CF3; (ii) a 5-membered heteroaryl selected from pyrrolyl, pyrazolyl, imidazolyl, oxazolyl, thiazolyl, triazolyl, oxadiazolyl, and thiadiazolyl; (iii) a 6?membered heteroaryl selected from pyridinyl, pyridazinyl, and pyrimidinyl; or (iv) a bicyclic heteroaryl selected from indolyl, pyrrolopyridinyl, pyrazolopyridinyl and benzo[d]oxazolyl; wherein each of said 5-membered, 6-membered, and bicyclic heteroaryl is substituted with zero to 1 Ra and zero to 1 Rb; and R1, R2, R3, R4, R5, R6, Ra, and Rb are defined herein. Also disclosed are methods of using such compounds as modulators of PI3K, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: February 26, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Rajeev S. Bhide, Douglas G. Batt, Robert J. Cherney, Lyndon A. M. Cornelius, Qingjie Liu, David Marcoux, James Neels, Michael A. Poss, Zheming Ruan, Qing Shi, Anurag S. Srivastava, Lan-ying Qin, Joseph A. Tino, Scott Hunter Watterson
  • Publication number: 20190023719
    Abstract: Disclosed are compounds of Formula (I) wherein: the two dotted lines represent either two single or two double bonds; Q is: R1 is F, Cl, —CN, or —CH3; R2 is Cl or —CH3; R3 is —C(CH3)2OH or —CH2CH2OH; Ra is H or —CH3; each Rb is independently F, Cl, —CH3, and/or —OCH3; and n is zero, 1, or 2. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
    Type: Application
    Filed: September 25, 2018
    Publication date: January 24, 2019
    Inventors: Douglas G. Batt, Myra Beaudoin Bertrand, George V. De Lucca, Michael A. Galella, Soo Sung Ko, Charles M. Langevine, Qingjie Liu, Qing Shi, Anurag S. Srivastava, Joseph A. Tino, Scott Hunter Watterson
  • Patent number: 10171377
    Abstract: An approach is provided for orchestrating computing resources between different computing environments. Data from first and second computing environments is monitored. The data specifies utilization of infrastructure, middleware, software testing tools, integrated development environments (IDEs), relationships among nodes, utilization of the nodes, and user behavior in the first and second computing environments. Based on the utilization of the infrastructure, middleware, tools, IDEs, node relationships and utilization, and user behavior, a pattern decision tree is updated. Based on the updated pattern decision tree and a user request that specifies requirements of the computing resources, an orchestration topology is generated that specifies a placement of the computing resources in the first and second computing environments.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: January 1, 2019
    Assignee: International Business Machines Corporation
    Inventors: Xue Feng Gao, Hui Qing Shi, Qing Feng Zhang, Zhi Feng Zhao
  • Patent number: 10138244
    Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, for use as a human PDE1 inhibitor.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: November 27, 2018
    Assignee: Eli Lilly and Company
    Inventors: Mark David Rekhter, Qing Shi